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LIVER TRANSPLANT RECIPIENT DEMOGRAPHY Patient Demographics (Please fill up in capital letters) Name Age/Sex: Blood Group Address Contact Numbers: Primary (Mobile) Attendant (Mobile) Local contact Home email: Diagnosis For office use Hospital No MELD CTP Referring doctor name, address & contact nos. BMI Height Cms weight Kgs DOA DEPARTMENT OF SURGICAL GASTROENETEROLOG JIPMER, PONDICHERRY-9. LIST OF INVESTIGATION TO BE DONE S.no Departments 1 Microbiology 2 Immunology 3 Biochemistry 4 Nuclear Medicine 5 Pulmonary Medicine 6 Cardiology 7 Radiology 8 Virology 9 Pathology 10 Transfusion Medicine 11 General Medicine Reports collected Pending reports MULTIDISCIPLINARY REPORT SUMMARY CHECKLIST S.No Multidisciplinary Team Name of the Member 1 Microbiology Dr.Hidendran Dr.Rahul 2 Biochemistry Dr.Nivedita 3 Pathology Dr.S.K.Varma 4 Radiology Dr.Ramkumar 5 Nuclear Medicine DR.Dhanapathi halnaik 6 Cardiology Dr.Santhosh Satheesh 7 Pulmonology Dr.Manju Rajaram 8 Hepatology Dr.Palanivel 9 Dentist Dr.Krishnan 10 Psychiatry Dr Vikas Menon 11 Anesthetist Dr.Lenin babu Dr.Sathyaprakash 12 Dietician 13 Physiotherapy 14 OBG Dr Veena 15 Nephrology Dr.Priyamvada 16 Clinical Pharmacology Dr.Adithan 17 Endocrinology Dr.Jayaprakash 18 Transfusion Dr.Rajendra Kulkarni 19 Co-ordinator Mrs. Subalaxmi 20 Billing/Insurance 21 Consent Fitness Remarks Clinical Data Presenting complaints/ Reason for referral to transplant centre: 1. 2. 3. Specific complaints related to liver disease: 1. Jaundice- Yes/No.If yes, then a. Whether it was cholestatic b. Was it associated with cholangitis 2. Encephalopathy- Yes/No. If yes, then a. Severity; Slowing/slurring of speech, loss of consciousness b. Number of episodes c. Whether hospital admission was required d. Grade 3. Ascites- Yes/No. If yes, then a. Whether it required diuretics b. Whether it required paracentesis If yes no: of: episodes: c. Was there any complication to the above medication/procedure 4. Spontaneous Bacterial Peritonitis- Yes/No. If yes, then a. Number of episodes b. Last episode 5. Upper Gastrointestinal Bleed- Yes/No. If yes, then a. Number of episodes b. Severity of episodes c. Treatment; i. Medical ii. Endoscopic(Banding/Sclerotherapy, sessions) 6. Hepatitis diagnosed previously- Yes/No. If yes, then a. Hepatitis B or C b. Viral characterization; i. Viral load ii. Genotype 7. Any other complaints Review of systems (Please include treatment details) 1. Respiratory: a. Asthma b. COPD 2. Cardiovascular: a. Hypertension b. Coronary artery disease 3. Performance status: a. Good (Can walk 500 meters or a flight of stairs without stopping or getting breathless) b. Average (Able to walk but needs support or to stop in between) c. Poor (Unable to walk independently) 4. Nutritional status: a. Good (Intake normal or nearly normal, no significant loss of weight) b. Average (Intake less than usual, weight loss present but not significant) c. Poor (Poor intake, loss of more than 10% of pre-illness weight over the last 6 months) 5. Gastrointestinal: a. Appetite b. Bowel movements 6. Genitourinary: a. Urinary complaints: Urine output, burning, bleeding 7. Gynaecological a. Menstrual history, menopause, HRT, breakthrough bleeding 8. Medical History: a. Diabetes mellitus b. Tuberculosis c. Cancer 9. Surgical History: a. Prior surgeries b. Anesthesia c. Complications d. Blood transfusions 10. Alcohol intake: a. Duration of intake b. Amount & type of alcohol c. History of recidivism d. Duration of abstinence 11. Personal History: a. Smoking b. Intravenous drug abuse c. Indigenous systems of medication used 12. Family History: a. Any history of liver disease b. History of malignancy c. Married d. Children e. Type of Family: Nuclear/Joint f. Support system: Strong/Weak g. Evaluation and vaccination status of spouse and children in Hepatitis B 13. Allergies a. To medication b. To foodstuff c. 14. Medications INVESTIGATIONS MICROBIOLOGY S.no Investigation Results S.no Investigation 1 Ig M Anti-HAV 14 CMV IgG 2 HbsAg(Screening) 15 CMV Ig M 3 Anti HCV 16 HSV 1&2 Ig M Ab 4 HCV RNA Quantitative assay 17 Herpes Zoster Ig G 5 HCV Genotype 18 Herpes Zoster Ig M 6 Anti-HBs 19 HIV screening 7 HBV DNA Quantitative 20 Toxoplasma Ig G 8 Hbe Ag 21 EB Virus 9 Anti-Hbe 22 Stool opportunistic infection 10 Ig M –Anti HBc 23 MRSA Screen 11 Ig G- Anti HBc 24 Throat swab 12 Rubella Ig G 13 Rubella Ig M Results MICROBIOLOGY CULTURES SPECIMEN DATE ORGANISM ANTIBIOTIC COUIRSE BLOOD URINE SPUTUM ASCITIC FLUID IMMUNOLOGY S.no Investigation Results S.no Investigation 1 ASCA IgA 7 ANCA (P&C) 2 ASCA IgG 8 SMA 3 ANA by IFA 9 Anti-LKM 4 AMA 10 Anti-thyroid antibody 5 Serum Immunoglobulin profile 11 HLA typing 6 Serum IgG4 estimation Results BIOCHEMISTRY S.no INVESTIGATIONS 1 Liver Function Test REPORTS S.no INVESTIGATIONS 5 Thyroid profile T.Bilirubin FT3 Direct FT4 REPORTS Indirect Total protein TSH 6 Tumour Markers Albumin AFP Globulin CA 125 AST CA19.9 ALT 7 Alpha-1-anti-trypsin levels 2 3 GGT 8 Blood urea Alkaline phosphatase 9 Serum creatinine Lipid profile 10 Blood ammonia Total cholesterol 11 Iron&Copper studies Triglycerides Serum Iron HDL-Chol TIBC LDL-Chol Serum Ferritin VLDL-Chol Serum copper Serum electrolytes Ceruloplasmin Sodium 12 Serum Zinc Level Potassium 13 PT/INR Chloride 14 S.fibrinogen Calcium 15 Creatinine Clearance Phosphorus Magnesium 4. Blood Glucose HbA1C BIOCHEMISTRY- ABG: NUCLEAR MEDICINE S.No Investigation 1 DTPA Scan 2. HIDA Scan 3. Bone Scan Report PULMONARY MEDICINE S.no Investigation 1 Sweat chloride 2. Pulmonary Function Test CARDIOLOGY S.no Investigation 1 ECG 2 Echo 3 Cardiac Catheterization Report Report 4 Micro bubble Echo cardiography 5 DSA 6 Hepatic/mesenteric Angiography RADIOLOGY S.no Investigation 1 X-ray 2 USG Abdomen Report Gross status: IHBR: 3 Doppler –liver Portal flow: HA flow: Hepatic Venous Flow: 4 64 Slice CECT Status of the liver,spleen: Portal venous anatomy: Collaterals: Leino renal shunt: Hepatic artery : Celiac Ostium stenosis: Any other: 5 MRI 6 MRCP PATHOLOGY S.no Investigation 1 HistopathologyBowel, Liver 2 immunohistochemistry 3 Frozen section HPE 4 Luminal pathology for opportunistic infection 5 Blood group 6 Complete blood count 7 Peripheral smear 8 Coagulation Profile INR a PTT.D –dimer FDP Report TRANFUSION MEDICINE S.no Investigation 1 Blood group 2 Cross matching 3 Auto antibody Screen 4 Direct and indirect Coomb’s test Reports GENERAL MEDICINE S.no Investigation 1 Reports HbA1C ENDOCRINOLOGY S.no Investigation 1 Reports Bone densitometry Dental assessmentOPG Dental caries / Infectious risk that could cause peri-operative infectious problems Obstetrics & Gynecology Mammogram Gynaecology assessment / Pap smear Comments Anaesthetic assessment: PAH Malampatti score Cardiac risk Pulmonary risk Coagulopathy Nutrition risk & Extubation related risks (consider Tri-flometry performance) Nutritional assessment Pre-transplant assessment of deficiency Assess pre-morbid weight Calculate 125% caloric requirement based on pre-morbid weight Recommending, pep-talking & monitoring compliance related to the Recommended diet Salt restriction (2 / 1 gm salt per day for decompensated CLD) Water restriction (< 1 lit / day for ascites that may require diuretics) Physiotherapy assessment Assess strength and weaknesses of individual muscle groups and girdles. Teach Isometric limb and girdle exercises in the gym and for at home Incentive spirometry for gradual improvement up to 4 times a day in the pre-tx waiting period. Psychiatric assessment Motivation status Cognitive abilities to give informed consent For alcoholics : insight into the problem Motivation for quitting Social / family support Likelihood of recidivism Need for formal rehab services Need for neuro-cognitive assessment scores Fit / not Hematology Hemoglobinopathies Underlying prothrombotic states Additional assessment : if necessary for pancytopenia Nephrology Proteinuria Underlying chronic renal disease Hepato-renal syndrome Potential for long term renal complications secondary to surgical stress & CNIs Immunization: Assess viral antibody titres and immune status against, HBV, VZV, CMV, HAV Advise immunization against HBV and other bacterial infections Risk & preparation for TB Help in peri-operative management of prophylaxis & treatment of infectious issues. Hepatology (Medical) assessment Endoscopy OGD Colonoscopy for pts >50 years age (if not done within last 10 years). Ascites : sampled / not : Comments Overall assessment with risk factors, indications and urgency Surgical assessment Surgical candidacy status H/O previous surgery / major portal hypertension Surgical issues (portal vein thrombosis), SOL in Liver Severity of coagulopathy / presence of ongoing DIC / severity of hypersplenism & pancytopenia Severity of decompensation, MELD score, Organ suitability (LD /Cad) Co-Morbidities Nutrition status, overall fitness and timings of LT. Final Recommendation Checked by Hepatologist Surgeon