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Europass Curriculum Vitae Personal information First name(s) / Surname(s) Address(es) Luca Pierelli Dipartimento Medicina Sperimentale Viale Regina Elena 324 Roma; Office at AO San Camillo Forlanini, Circonvallazione Gianicolense 87, 00152 Roma (Pad.A.Cesalpino) Occupational field Technical science of laboratory medicine (MED46) Page 1/7 - Curriculum vitae of Surname(s) First name(s) For more information on Europass go to http://europass.cedefop.europa.eu © European Union, 2004-2010 24082010 Dates 2010 until now Work experience Director of Transfusion Department Lazio Ovest at AO San Camillo Forlanini in convention with Sapienza University School of Medicine Dates 2008 until now Work experience Director of Immunohematology and Transfusion Medicine Unit at AO San Camillo Forlanini of Rome in convention with Sapienza University School of Medicine Dates 2008 Work experience Charged with the role of Associate Professor for the scientific area MED46/Technical Sciences of Laboratory Medicine at Sapienza University Medical School of Rome Dates 2007 Work experience Charged with the role of Director of Transfusion Department Roma Ovest Dates 2007 Work experience Charged with the role of Director of Immunohematology and Transfusion Medicine Unit at AO San Camillo Forlanini of Rome Dates 2006 Work experience Qualified in the role of Associate Professor for the scientific area MED46/Technical Sciences of Laboratory Medicine Dates 2006 Work experience Charged with the role of Director of Transfusion Department Lazio Nord Dates 2002 Work experience Charged with the role of Director of Immunohematology and Transfusion Medicine Unit at ASL Viterbo Dates 1998 Work experience Confirmed in the role of medical researcher in the area of Hematology (F07G) Dates 1995-1998 Work experience Medical Researcher at Medical Semiotics Institute of Catholic of Sacred Heart University of Rome and Medical Manager of 1st level at Medical Semiotics Institute of Catholic of Sacred Heart University of Rome Dates 1990-1995 Work experience Medical assistant at Laboratory Hematology and Transfusion Medicine Unit of Medical Semiotics Institute of Catholic of Sacred Heart University of Rome Occupation or position held Associate Professor for the scientific area Technical Sciences of Laboratory Medicine at Sapienza University of Rome; Director of Immunohematology and Transfusion Medicine Unit/Transfusion Department Lazio Ovest at AO San Camillo Forlanini in convention with Sapienza University School of Medicine Page 2/7 - Curriculum vitae of Surname(s) First name(s) For more information on Europass go to http://europass.cedefop.europa.eu © European Union, 2004-2010 24082010 Main activities and responsibilities Name and address of employer Sector Teaching activities at Nursing University School (Istology, Anatomy and Physiology; Nursing in Critic Area and Emergency) and Biomedical University School for Technicians (Laboratory Techniques of Clinical Pathology). Scientific activities in the field of hematopoietic stem cell collection and processing, GMP production and clinical use of lymphocyte with killer activity and mesenchymal stem cells. Scientific activities in the field of Immunohematology, Transfusion Medicine, Apheresis and Regenerative Medicine. Direction and general management of Lazio Ovest Transfusion Department and Immunohematology and Transfusion Medicine Unit at AO San Camillo Forlanini of Rome. Sapienza University of Rome; Piazzale Aldo Moro 5, 00185 Roma Nursing School (Istology, Anatomy and Physiology; Nursing in Critic Area and Emergency) and Biomedical University School for Technicians (Laboratory Techniques of Clinical Pathology) Education and training Dates 1986-1989 Title of qualification awarded Specialization in Clinical and Laboratory Hematology Name and type of organisation providing Catholic University of Sacred Heart Medical School of Rome education and training Dates 1980-1986 Title of qualification awarded Degree in Medical Doctor Name and type of organisation providing education and training Sapienza University School of Medicine of Rome Personal skills and competences Hematopoietic stem cell collection and processing, GMP production and clinical use of lymphocyte with killer activity and mesenchymal stem cells. Immunohematology, Transfusion Medicine, Apheresis and Regenerative Medicine. Mother tongue(s) Italian Other language(s) Self-assessment English Understanding European level (*) Language English Listening Independent B2 user Speaking Reading Independent B2 user W r i t i n g Spoken interaction Spoken production Independent Independent B2 B2 user user Language (*) Common European Framework of Reference for Languages Additional information Receiving Annexes Wednesday 09.00-11.00 AM at his own office, AO San Camillo Forlanini, Circonvallazione Gianicolense 87, 00152 Roma (Pad.A.Cesalpino) List any items attached. Recent Scientific Publication (20052014) Page 3/7 - Curriculum vitae of Surname(s) First name(s) For more information on Europass go to http://europass.cedefop.europa.eu © European Union, 2004-2010 24082010 1: Perseghin P, Marchetti M, Pierelli L, Olivieri A, Introna M, Lombardini L, Accorsi P, Petrini C, Risso M, Bosi A; Società Italiana di Emaferesi e Manipolazione Cellulare (SIDEM), Gruppo Italiano Trapianto Midollo Osseo (GITMO) and Centro Nazionale Trapianti (CNT). A policy for the disposal of autologous hematopoietic progenitor cells: report from an Italian consensus panel. Transfusion. 2014 Mar 24. doi: 10.1111/trf.12619 2: Vacca M, Perseghin P, Accorsi P, Pierelli L; On the behalf of SIdEM Board. Central venous catheter insertion in peripheral blood hematopoietic stem cell sibling donors: The SIdEM (Italian Society of Hemapheresis and Cell Manipulation) point of view. Transfus Apher Sci. 2014 Feb 14. pii: S1473-0502(14)00029-9. doi: 10.1016/j.transci.2014.02.001. [ 3: Iudicone P, Fioravanti D, Bonanno G, Miceli M, Lavorino C, Totta P, Frati L, Nuti M, Pierelli L. Pathogen-free, plasma-poor platelet lysate and expansion of human mesenchymal stem cells. J Transl Med. 2014 Jan 27;12:28. doi: 10.1186/1479-5876-12-28. PubMed PMID: 24467837; 4: Siciliano C, Ibrahim M, Scafetta G, Napoletano C, Mangino G, Pierelli L, Frati G, De Falco E. Optimization of the isolation and expansion method of human mediastinal-adipose tissue derived mesenchymal stem cells with virally inactivated GMP-grade platelet lysate. Cytotechnology. 2013 Dec 4. 5: Olivieri J, Pierelli L, Introna M, Accorsi P, Bosi A, Perseghin P, Risso M, Pandolfi A, Mancini S, Marchetti M, Dal Pozzo S, Gotti E, Rambaldi A, Leoni P, Olivieri A; Gitmo (Gruppo Italiano Trapianto di Midollo Osseo)–SIDEM (Società Italiana di Emaferesi e Manipolazione Cellulare) Working Group on SCU Disposal. Kinetics of the use of cryopreserved autologous stem cell grafts: a GITMO-SIDEM survey. Cytotherapy. 2014 Jan;16(1):101-10. doi: 10.1016/j.jcyt.2013.07.001. 6: Matteocci A, Pierelli L. Red blood cell alloimmunization in sickle cell disease and in thalassaemia: current status, future perspectives and potential role of molecular typing. Vox Sang. 2014 Apr;106(3):197-208. doi: 10.1111/vox.12086. 7: Pierelli L, Berto P, Accorsi P, Milone G, Lopatriello S, Aiello A, Iacopino P, Olivieri A, Rambaldi A, Bosi A. The costs of mobilisation and collection of peripheral blood stem cells in multiple myeloma and lymphoma in an European country: results from The Gruppo Italiano Trapianto Midollo Osseo (GITMO) and Società Italiana di Emaferesi e Manipolazione Cellulare (SIdEM) survey. Transfus Apher Sci. 2013 Dec;49(3):615-22. doi: 10.1016/j.transci.2013.07.025. 8: Perseghin P, Marchetti M, Messina C, Mazzoni A, Carlier P, Perotti C, Salvaneschi L, Risso M, Fanin R, Olivieri A, Accorsi P, Locatelli F, Bacigalupo A, Pierelli L, Bosi A; Società Italiana di Emaferesi e Manipolazione Cellulare; Gruppo Italiano Trapianto di Midollo Osseo. Best practice recommendations in: (1) Peripheral blood stem cell mobilization and collection and (2) acute and chronic GvHD treatment using extracorporeal photopheresis. A joint effort from SIdEM (Società Italiana di Emaferesi e Manipolazione Cellulare) and GITMO (Gruppo Italiano Trapianto di Midollo Osseo). Transfus Apher Sci. 2013 Apr;48(2):195-6. doi: 10.1016/j.transci.2013.02.034. 9: Spoliti M, Iudicone P, Leone R, De Rosa A, Rossetti FR, Pierelli L. In vitro release and expansion of mesenchymal stem cells by a hyaluronic acid scaffold used in combination with bone marrow. Muscles Ligaments Tendons J. 2013 Jan 21;2(4):289-94. 10: Pierelli L, Perseghin P. Plerixafor (Mozobil) and other mobilizing agents. Page 4/7 - Curriculum vitae of For more information on Europass go to http://europass.cedefop.europa.eu Surname(s) First name(s) © European Union, 2004-2010 24082010 Transfus Apher Sci. 2013 Apr;48(2):133-5. doi: 10.1016/j.transci.2013.02.005. 11: Romanò L, Velati C, Cambiè G, Fomiatti L, Galli C, Zanetti AR; SIMTI study group for HBV infection among first-time blood donors. Hepatitis B virus infection among first-time blood donors in Italy: prevalence and correlates between serological patterns and occult infection. Blood Transfus. 2013 Apr;11(2):281-8. doi: 10.2450/2012.0160-12 12: Pierelli L, Perseghin P, Marchetti M, Messina C, Perotti C, Mazzoni A, Bacigalupo A, Locatelli F, Carlier P, Bosi A; Società Italiana di Emaferesi and Manipolazione Cellulare (SIdEM); Gruppo Italiano Trapianto Midollo Osseo (GITMO). Extracorporeal photopheresis for the treatment of acute and chronic graft-versus-host disease in adults and children: best practice recommendations from an Italian Society of Hemapheresis and Cell Manipulation (SIdEM) and Italian Group for Bone Marrow Transplantation (GITMO) consensus process. Transfusion. 2013 Oct;53(10):2340-52. doi: 10.1111/trf.12059. 13: Weltert L, Nardella S, Rondinelli MB, Pierelli L, De Paulis R. Reduction of allogeneic red blood cell usage during cardiac surgery by an integrated intraand postoperative blood salvage strategy: results of a randomized comparison. Transfusion. 2013 Apr;53(4):790-7. doi: 10.1111/j.1537-2995.2012.03836.x. 14: Piccirillo N, Vacca M, Lanti A, Ipsevich F, Maresca M, Fiorelli E, Bianchi M, Adorno G, Pierelli L, Majolino I, Leone G, Zini G. Poor mobilizer: a retrospective study on proven and predicted incidence according to GITMO criteria. Transfus Apher Sci. 2012 Oct;47(2):217-21. doi: 10.1016/j.transci.2012.06.008. 15: Quaglietta A, Nicolucci A, Accorsi P, Pompa A, Pierelli L, Iacone A. Survey of current practice for monitoring and management of platelet refractoriness in Italy. Transfus Apher Sci. 2012 Dec;47(3):271-6. doi: 10.1016/j.transci.2012.04.003. 16: Rutella S, Iudicone P, Bonanno G, Fioravanti D, Procoli A, Lavorino C, Foddai ML, Lorusso D, Martinelli E, Vacca M, Ipsevich F, Nuti M, Scambia G, Pierelli L. Adoptive immunotherapy with cytokine-induced killer cells generated with a new good manufacturing practice-grade protocol. Cytotherapy. 2012 Aug;14(7):841-50. doi: 10.3109/14653249.2012.681038. 17: Napoletano C, Zizzari IG, Rughetti A, Rahimi H, Irimura T, Clausen H, Wandall HH, Belleudi F, Bellati F, Pierelli L, Frati L, Nuti M. Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation. Eur J Immunol. 2012 Apr;42(4):936-45. doi: 10.1002/eji.201142086. 18: Mancini R, Marinelli L, Mirante N, Gallo A, Matteocci A, Terlizzi F, Palange M, Fioravanti D, Donnini L, Pierelli L. Evaluation of haemoglobin, haematocrit, haemolysis, residual protein content and leucocytes in 345 red blood cell concentrates used for the treatment of patients with β-thalassaemia. Blood Transfus. 2012 Jan;10(1):39-44. doi: 10.2450/2011.0056-10. 19: Rondinelli MB, Pallotta F, Rossetti S, Musumeci F, Menichetti A, Bianco F, Gaffi M, Pierelli L. Integrated strategies for allogeneic blood saving in major elective surgery. Transfus Apher Sci. 2011 Dec;45(3):281-5. doi: 10.1016/j.transci.2011.10.009. 20: Pierelli L, Perseghin P, Marchetti M, Accorsi P, Fanin R, Messina C, Olivieri A, Risso M, Salvaneschi L, Bosi A; Società Italiana Di Emaferesi and Page 5/7 - Curriculum vitae of Surname(s) First name(s) For more information on Europass go to http://europass.cedefop.europa.eu © European Union, 2004-2010 24082010 Manipolazione Cellulare (SIDEM); Gruppo Italiano Trapianto Midollo Osseo (GITMO). Best practice for peripheral blood progenitor cell mobilization and collection in adults and children: results of a Società Italiana Di Emaferesi e Manipolazione Cellulare (SIDEM) and Gruppo Italiano Trapianto Midollo Osseo (GITMO) consensus process. Transfusion. 2012 Apr;52(4):893-905. doi: 10.1111/j.1537-2995.2011.03385.x. 21: Pierelli L, Fioravanti D, Patti D, Iudicone P, Scocchera R, Pandolfi A, Nuti M. Counting of leukocytes in samples from G-CSF mobilized donors, leukapheresis products, and cord blood: the performances of an analyzer with dedicated profiles. Int J Lab Hematol. 2012 Apr;34(2):154-63. doi: 10.1111/j.1751-553X.2011.01373.x. 22: Pierelli L, Zennaro F, Chiarioni S, Miceli M. The application of multiparameter reference intervals for pre-donation capillary blood counts: the experience of a single institution. Transfus Med. 2011 Oct;21(5):344-8. doi: 10.1111/j.1365-3148.2011.01094.x. 23: Bonanno G, Iudicone P, Mariotti A, Procoli A, Pandolfi A, Fioravanti D, Corallo M, Perillo A, Scambia G, Pierelli L, Rutella S. Thymoglobulin, interferon-γ and interleukin-2 efficiently expand cytokine-induced killer (CIK) cells in clinical-grade cultures. J Transl Med. 2010 Dec 7;8:129. doi: 10.1186/1479-5876-8-129. 24: Pierelli L, Zennaro F, Patti D, Miceli M, Iudicone P, Mannella E. Evaluation of the analytical performances of a portable, 18-parameter hemometric system using capillary blood samples for blood donor enrolment. Vox Sang. 2010 Feb;98(2):145-50. doi: 10.1111/j.1423-0410.2009.01256.x. 25: Bonanno G, Mariotti A, Procoli A, Corallo M, Scambia G, Pierelli L, Rutella S. Interleukin-21 induces the differentiation of human umbilical cord blood CD34-lineage- cells into pseudomature lytic NK cells. BMC Immunol. 2009 Aug 27;10:46. doi: 10.1186/1471-2172-10-46. 26: Rutella S, Bonanno G, Procoli A, Mariotti A, Corallo M, Prisco MG, Eramo A, Napoletano C, Gallo D, Perillo A, Nuti M, Pierelli L, Testa U, Scambia G, Ferrandina G. Cells with characteristics of cancer stem/progenitor cells express the CD133 antigen in human endometrial tumors. Clin Cancer Res. 2009 Jul 1;15(13):4299-311. doi: 10.1158/1078-0432.CCR-08-1883. 27: Iudicone P, Miceli M, Palange M, Agresti A, Gallo A, Isacchi G, Girolami E, Pierelli L, Mannella E. Hepatitis B virus blood screening: impact of nucleic amplification technology testing implementation on identifying hepatitis B surface antigen non-reactive window period and chronic infections. Vox Sang. 2009 May;96(4):292-7. doi: 10.1111/j.1423-0410.2009.01171.x. 28: Ferrandina G, Bonanno G, Pierelli L, Perillo A, Procoli A, Mariotti A, Corallo M, Martinelli E, Rutella S, Paglia A, Zannoni G, Mancuso S, Scambia G. Expression of CD133-1 and CD133-2 in ovarian cancer. Int J Gynecol Cancer. 2008 May-Jun;18(3):506-14. 29: Bonanno G, Mariotti A, Procoli A, Corallo M, Rutella S, Pessina G, Scambia G, Mancuso S, Pierelli L. Human cord blood CD133+ cells immunoselected by a clinical-grade apparatus differentiate in vitro into endothelial- and cardiomyocyte-like cells. Transfusion. 2007 Feb;47(2):280-9. 30: Pierelli L, Maresca M, Piccirillo N, Pupella S, Gozzer M, Foddai ML, Vacca M, Adorno G, Coppetelli U, Paladini U. Accurate prediction of autologous stem cell apheresis yields using a double variable-dependent method assures systematic efficiency control of continuous flow collection procedures. Vox Sang. 2006 Page 6/7 - Curriculum vitae of Surname(s) First name(s) For more information on Europass go to http://europass.cedefop.europa.eu © European Union, 2004-2010 24082010 Aug;91(2):126-34. 31: Ferrandina G, Perillo A, Distefano M, D'Agostino G, Gallotta V, Pierelli L, Scambia G. Carboplatin-based neoadjuvant treatment with peripheral blood stem cell and growth factor support in locally advanced cervical cancer patients with bulky metastatic lymph nodes. Eur J Obstet Gynecol Reprod Biol. 2007 Apr;131(2):236-8. 32: Rutella S, Bonanno G, Procoli A, Mariotti A, de Ritis DG, Curti A, Danese S, Pessina G, Pandolfi S, Natoni F, Di Febo A, Scambia G, Manfredini R, Salati S, Ferrari S, Pierelli L, Leone G, Lemoli RM. Hepatocyte growth factor favors monocyte differentiation into regulatory interleukin (IL)-10++IL-12low/neg accessory cells with dendritic-cell features. Blood. 2006 Jul 1;108(1):218-27. 33: Perillo A, Ferrandina G, Pierelli L, Bonanno G, Scambia G, Mancuso S. Stem cell-based treatments for gynecological solid tumors. Eur Rev Med Pharmacol Sci. 2005 Mar-Apr;9(2):93-102. Review. Roma 24/04/2014 Prof. Luca Pierelli Page 7/7 - Curriculum vitae of Surname(s) First name(s) For more information on Europass go to http://europass.cedefop.europa.eu © European Union, 2004-2010 24082010