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Team Members
Regulation of microtubule dynamics and functions
Carsten Janke CNRS Research Director
TEAM JANKE
Team Leader
[email protected] Tel: +33 1 69 86 31 27
1994: Diploma in Biochemistry, University of Leipzig, Germany
1998: PhD in Biochemistry-Neurochemistry, University of Leipzig, Germany
1998-1999: Postdoc in biophysics, CBM, CNRS Orléans, France
1999-2002: Postdoc in yeast cell biology, Beatson Institut for Cancer Research, Glasgow, UK
2002-2005: Postdoc & staff scientist (CR1), CRBM, CNRS Montpellier, France
2005-2010: Junior group leader, CRBM, CNRS Montpellier, France
2009: DR2 CNRS
2010 - today: Senior group leader at the Institut Curie, Orsay, France
2013: DR1 CNRS
Scientific achievements and prices
2008
2014
EMBO Young Investigator
EMBO member
Experience with network coordination and grant
applications
Coordinator of 8 research grants (HFSP, ANR, INCA, …).
Co-funder and scientific coordinator of a European Initial Training Network (ITN)
19 successful grant applications
20 successful applications for fellowships in the Janke team.
Implications in the scientific community
Established a large number of scientific collaborations
Organizer of an EMBO conference series (2010, 2012, 2016), and an EMBL/EMBO symposium
(2016) on Microtubules
Organizer of a French-Indian Cytoskeleton workshop (2015)
INSTITUT CURIE, 20 rue d’Ulm, 75248 Paris Cedex 05, France | 1
Team Members
Regulation of microtubule dynamics and functions
Reviewer for many grant agencies and scientific journals
Member for evaluation commissions, scientific advisory boards, editorial board of J Cell Science
Key publications
Year of publication 2017
Akendengue L., Trepout S., Grana M., Voegele A., Janke C., Raynal B., Chenal A., Marco S.,
Wehenkel A.M. (2017 Mar 30)
Bacterial kinesin light chain (Bklc) links the Btub cytoskeleton to membranes
SCIENTIFIC REPORTS : 7 : DOI : 10.1038/srep45668
Year of publication 2014
Olivia Tort, Sebastián Tanco, Cecilia Rocha, Ivan Bièche, Cecilia Seixas, Christophe Bosc, Annie
Andrieux, Marie-Jo Moutin, Francesc Xavier Avilés, Julia Lorenzo, Carsten Janke (2014 Oct 1)
The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational
removal of acidic amino acids.
Molecular biology of the cell : 3017-27 : DOI : 10.1091/mbc.E14-06-1072
Cecilia Rocha, Laura Papon, Wulfran Cacheux, Patricia Marques Sousa, Valeria Lascano, Olivia
Tort, Tiziana Giordano, Sophie Vacher, Benedicte Lemmers, Pascale Mariani, Didier Meseure, Jan
Paul Medema, Ivan Bièche, Michael Hahne, Carsten Janke (2014 Oct 1)
Tubulin glycylases are required for primary cilia, control of cell proliferation and
tumor development in colon.
The EMBO journal : 2247-60 : DOI : 10.15252/embj.201488466
Year of publication 2013
Montserrat Bosch Grau, Gloria Gonzalez Curto, Cecilia Rocha, Maria M Magiera, Patricia Marques
Sousa, Tiziana Giordano, Nathalie Spassky, Carsten Janke (2013 Aug 5)
Tubulin glycylases and glutamylases have distinct functions in stabilization and
motility of ependymal cilia.
The Journal of cell biology : 441-51 : DOI : 10.1083/jcb.201305041
Year of publication 2010
Krzysztof Rogowski, Juliette van Dijk, Maria M Magiera, Christophe Bosc, Jean-Christophe
INSTITUT CURIE, 20 rue d’Ulm, 75248 Paris Cedex 05, France | 2
Team Members
Regulation of microtubule dynamics and functions
Deloulme, Anouk Bosson, Leticia Peris, Nicholas D Gold, Benjamin Lacroix, Montserrat Bosch
Grau, Nicole Bec, Christian Larroque, Solange Desagher, Max Holzer, Annie Andrieux, Marie-Jo
Moutin, Carsten Janke (2010 Nov 12)
A family of protein-deglutamylating enzymes associated with
neurodegeneration.
Cell : 564-78 : DOI : 10.1016/j.cell.2010.10.014
Benjamin Lacroix, Juliette van Dijk, Nicholas D Gold, Julien Guizetti, Gudrun Aldrian-Herrada,
Krzysztof Rogowski, Daniel W Gerlich, Carsten Janke (2010 Jun 14)
Tubulin polyglutamylation stimulates spastin-mediated microtubule severing.
The Journal of cell biology : 945-54 : DOI : 10.1083/jcb.201001024
Year of publication 2009
Krzysztof Rogowski, François Juge, Juliette van Dijk, Dorota Wloga, Jean-Marc Strub, Nicolette
Levilliers, Daniel Thomas, Marie-Hélène Bré, Alain Van Dorsselaer, Jacek Gaertig, Carsten Janke
(2009 Jun 12)
Evolutionary divergence of enzymatic mechanisms for posttranslational
polyglycylation.
Cell : 1076-87 : DOI : 10.1016/j.cell.2009.05.020
Year of publication 2007
Juliette van Dijk, Krzysztof Rogowski, Julie Miro, Benjamin Lacroix, Bernard Eddé, Carsten Janke
(2007 May 11)
A targeted multienzyme mechanism for selective microtubule
polyglutamylation.
Molecular cell : 437-48 : DOI : 10.1016/j.molcel.2007.04.012
Year of publication 2005
Carsten Janke, Krzysztof Rogowski, Dorota Wloga, Catherine Regnard, Andrey V Kajava, JeanMarc Strub, Nevzat Temurak, Juliette van Dijk, Dominique Boucher, Alain van Dorsselaer, Swati
Suryavanshi, Jacek Gaertig, Bernard Eddé (2005 Jun 17)
Tubulin polyglutamylase enzymes are members of the TTL domain protein
family.
Science (New York, N.Y.) : 1758-62 : DOI : 10.1126/science.1113010
INSTITUT CURIE, 20 rue d’Ulm, 75248 Paris Cedex 05, France | 3