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National Imaging Associates, Inc. Clinical guidelines SELLA CT (Includes sella and posterior fossa) CPT Codes: 70480, 70481, 70482 Guideline Number: NIA_CG_005-3 Responsible Department: Clinical Operations Original Date: Page 1 of 3 September 1997 Last Review Date: Last Revised Date: Implementation Date: September 2014 September 2014 January 2015 INTRODUCTION: The sella turcica is a saddle-shaped depression in the sphenoid bone at the base of the human skull which holds the pituitary gland. Computed tomography (CT) is useful in the delineation of the osseous margins of the sella. It is particularly helpful in evaluating the bony changes related to pathologic processes. The most frequent finding is a change in the size of the sella turcica such as an enlargement unaccompanied by bone erosion. The most common causes are the presence of interstellar adenomas and empty sella syndrome. The shape of the sella may also be affected by pathological conditions, such as Down syndrome, Williams’ syndrome, Sickle syndrome, and lumbosacral myelomeniogocele. INDICATIONS FOR SELLA CT: For assessment of proptosis (exophthalmos). For evaluation of progressive vision loss/visual field deficit. For evaluation of decreased range of motion of the eyes. For screening and evaluation of ocular tumor, pituitary adenoma and parasellar bony structures for the evaluation of certain sellar tumors. For screening and assessment of known or suspected optic neuritis if MRI is contraindicated or is unable to be performed. For screening and evaluation of suspected orbital Pseudotumor. ADDITIONAL INFORMATION RELATED TO SELLA CT: Request for a follow-up study - A follow-up study may be needed to help evaluate a patient’s progress after treatment, procedure, intervention or surgery. Documentation requires a medical reason that clearly indicates why additional imaging is needed for the type and area(s) requested. Proptosis or exophthalmos – Proptosis is a bulging of one or two of the eyes. Bulging of the eyes may be caused by hyperthyroidism (Graves’ disease) or it may be caused by orbital tumors, cancer, infection, inflammation and arteriovenous malformations. The extent of proptosis, the abnormal bulging of one or two eyes, can be assessed by using a mid-orbital axial scan. Orbital Pseudotumor – Pseudotumor may appear as a well-defined mass or it may mimic a malignancy. A sclerosing orbital Pseudotumor can mimic a lacrimal gland tumor. 1— Sella CT 2015 Proprietary Grave’s Disease – Enlargement of extraocular muscles and exophthalmos are features of Grave’s disease. CT may show unilateral or bilateral involvement of single or multiple muscles. It will show fusiform muscle enlargement with smooth muscle borders, especially posteriorly and pre-septal edema may be evident. Quantitative CT imaging of the orbit evaluates the size and density values of extraocular muscles and the globe position and helps in detecting opthalmopathy in Grave’s disease. Orbital Trauma – CT is helpful in assessing trauma to the eye because it provides excellent visualization of soft tissues, bony structures and foreign bodies. Ocular Tumor – In the early stages, a choroidal malignant melanoma appears as a localized thickening of sclero-uveal layer. It may be seen as a well defined mass if it is more than 3 mm thick. 2— Sella CT 2015 Proprietary REFERENCES American College of Radiology. (2014). ACR Appropriateness Criteria® Retrieved from https://acsearch.acr.org/list. Hickman, S.J., Dalton, C.M., Miller, D.H. & Plant, G.T. (2002). Management of acute optic neuritis. Lancet, 360(9349), 1953-1962. doi: 10.1016/S0140-6736(02)11919-2. Shields, J.A., & Shields, C.L. (2004). Orbital cysts of childhood--classification, clinical features, and management. Survey of Ophthalmology, 49(3), 281-299. doi:10.1016/j.survophthal.2004.02.001. 3— Sella CT 2015 Proprietary