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Curriculum vitae
PERSONAL INFORMATION
Ruben Casado Arroyo
WORK EXPERIENCE
August 2013–Present
Director of the Coronary Care Unit. Cardiology Deparment
Erasmus Hospital. Université Libre de Bruxelles., Brussels (Belgium)
Research in the field of Cardiac Arrhythmias
August 2013–Present
Associate Professor of Medicine
Université Libre de Bruxelles, Brussels (Belgium)
EDUCATION AND TRAINING
September 2015–Present
Executive MSc Health Economics, Policy and Management
London School of Economics and Political Science, London (United Kingdom)
April 2015–June 2015
Research Fellow of Cardiac Electrophysiology and Pacing
University of Pennsylvania. Cardiology Department, Philadelphia (United States)
January 2008–June 2014
Doctor of Philosophy (PhD)
University of Zaragoza, Zaragoza (Spain)
Award of the best PhD of the University
January 2011–December 2013
Doctor of Philosophy (PhD)
Vrije Universiteit Brussel, Brussels (Spain)
September 2006–January 2007
Research Fellow of Intensive Care
Harvard Medical School. Massachusetts General Hospital, Boston (United States)
July 2005–October 2010
Research Fellow, Cardiovascular and Pharmacological Sciences
University G. d’Annunzio, Chieti (Italy)
July 2007–June 2011
Specialist in Cardiology
University of Zaragoza, Zaragoza (Spain)
May 2002–June 2007
Intensive Care Medicine
University of Santiago de Compostela, Santiago de Compostela (Spain)
September 1995–June 2001
Medical Degree
University of Cantabria, Santander (Spain)
ADDITIONAL INFORMATION
Expertise
8/8/16
Cardiac arrhythmias (atrial fibrillation, atrial flutter, atrial tachycardia, ventricular tachycardia, ventricular
fibrillation, Brugada syndrome, Long QT).
© European Union, 2002-2015 | http://europass.cedefop.europa.eu
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Curriculum vitae
Ruben Casado Arroyo
Devices (Pacemakers, defibrillators).
Coronary Care (Myocardial infarction, cardiac ischemia)
Intensive Care Medicine
Publications
▪ Long-Term Trends in Newly Diagnosed Brugada Syndrome: Implications for Risk Stratification.
Casado-Arroyo R, Berne P, Rao JY, Rodriguez-Mañero M, Levinstein M, Conte G, Sieira J,
Namdar M, Ricciardi D, Chierchia GB, de Asmundis C, Pappaert G, La Meir M, Wellens F,
Brugada J, Brugada P. J Am Coll Cardiol. 2016 Aug 9;68(6):614-23.
▪ Clinical characterisation and long-term prognosis of women with Brugada syndrome. Sieira J,
Conte G, Ciconte G, de Asmundis C, Chierchia GB, Baltogiannis G, Di Giovanni G, Saitoh Y, Irfan
G, Casado-Arroyo R, Juliá J, La Meir M, Wellens F, Wauters K, Pappaert G, Brugada P. Heart.
2016 Mar;102(6):452-8. doi: 10.1136/heartjnl-2015-308556. Epub 2016 Jan 6. PMID: 26740482
▪ A Balanced View of Efficacy and Safety of Aspirin in Cardiovascular Diseases. Casado-Arroyo R,
Lanas A, Brugada P. Curr Pharm Des. 2015;21(35):5101-7. PMID: 26369681
▪ Asymptomatic Brugada Syndrome: Clinical Characterization and Long-Term Prognosis. Sieira J,
Ciconte G, Conte G, Chierchia GB, de Asmundis C, Baltogiannis G, Di Giovanni G, Saitoh Y, Irfan
G, Casado-Arroyo R, Julià J, La Meir M, Wellens F, Wauters K, Pappaert G, Brugada P. Circ
Arrhythm Electrophysiol. 2015 Oct;8(5):1144-50.
▪ Prognostic value of programmed electrical stimulation in Brugada syndrome: 20 years experience.
Sieira J, Conte G, Ciconte G, de Asmundis C, Chierchia GB, Baltogiannis G, Di Giovanni G, Saitoh
Y, Irfan G, Casado-Arroyo R, Juliá J, La Meir M, Wellens F, Wauters K, Van Malderen S, Pappaert
G, Brugada P. Circ Arrhythm Electrophysiol. 2015 Aug;8(4):777-84.
▪ [Atrial fibrillation: recent progress]. Casado Arroyo R, Van de Borne P. Rev Med Brux. 2014
Sep;35(4):314-20. French. PMID: 25675636
▪ [Purpura and necrosis of sudden onset in a patient with fever]. Pastushenko I, Gracia-Cazaña T,
Casado-Arroyo R. Enferm Infecc Microbiol Clin. 2015 Feb;33(2):129-30.
▪ The clinical significance of pregnancy in Brugada syndrome. Rodríguez-Mañero M, Casado-Arroyo
R, Sarkozy A, Leysen E, Sieira JA, Namdar M, Conte G, Levinstein M, Chierchia GB, de Asmundis
C, Brugada P. Rev Esp Cardiol (Engl Ed). 2014 Mar;67(3):176-80.
▪ Second-generation cryoballoon ablation for paroxysmal atrial fibrillation: 1-year follow-up. Chierchia
GB, Di Giovanni G, Ciconte G, de Asmundis C, Conte G, Sieira-Moret J, Rodriguez-Mañero M,
Casado R, Baltogiannis G, Namdar M, Saitoh Y, Paparella G, Mugnai G, Brugada P. Europace.
2014 May;16(5):639-44.
▪ Comparison of the patient-activated event recording system vs. traditional 24 h Holter
electrocardiography in individuals with paroxysmal palpitations or dizziness. de Asmundis C, Conte
G, Sieira J, Chierchia GB, Rodriguez-Manero M, Di Giovanni G, Ciconte G, Levinstein M,
Baltogiannis G, Saitoh Y, Casado-Arroyo R, Brugada P. Europace. 2014 Aug;16(8):1231-5. doi:
10.1093/europace/eut411. Epub 2014 Feb 26. PMID: 24574492
▪ Clinical characteristics, management, and prognosis of elderly patients with Brugada syndrome.
Conte G, DE Asmundis C, Sieira J, Levinstein M, Chierchia GB, DI Giovanni G, Baltogiannis G,
Ciconte G, Saitoh Y, Casado-Arroyo R, Pappaert G, Brugada P. J Cardiovasc Electrophysiol. 2014
May;25(5):514-9. doi: 10.1111/jce.12359. Epub 2014 Jan 21. PMID: 24400668
▪ Initial experience of three-minute freeze cycles using the second-generation cryoballoon ablation:
acute and short-term procedural outcomes. Chierchia GB, Di Giovanni G, Sieira-Moret J, de
Asmundis C, Conte G, Rodriguez-Mañero M, Casado-Arroyo R, Baltogiannis G, Paparella G,
Ciconte G, Sarkozy A, Brugada P. J Interv Card Electrophysiol. 2014 Mar;39(2):145-51. doi:
8/8/16
© European Union, 2002-2015 | http://europass.cedefop.europa.eu
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Curriculum vitae
Ruben Casado Arroyo
10.1007/s10840-013-9855-x. Epub 2013 Dec 7. PMID: 24317917
▪ A novel electrocardiographic index for the diagnosis of diastolic dysfunction. Namdar M, Biaggi P,
Stähli B, Bütler B, Casado-Arroyo R, Ricciardi D, Rodríguez-Mañero M, Steffel J, Hürlimann D,
Schmied C, de Asmundis C, Chierchia GB, Sarkozy A, Lüscher TF, Jenni R, Duru F, Paulus WJ,
Brugada P. PLoS One. 2013 Nov 5;8(11):e79152. doi: 10.1371/journal.pone.0079152. eCollection
2013. PMID: 24223898
▪ ICD function and dysfunction in patients with arrhythmogenic cardiac diseases: the role of home
monitoring. De Asmundis C, Ricciardi D, Namdar M, Pappaert G, Rodríguez-Mañero M, Wauters
K, Casado-Arroyo R, Rao JJ, Bayrak F, Chierchia GB, Sarkozy A, Brugada P. Acta Cardiol. 2013
Aug;68(4):387-94. PMID: 24187765
▪ Pulmonary vein isolation in patients with Brugada syndrome and atrial fibrillation: a 2-year follow-up.
Conte G, Chierchia GB, Wauters K, De Asmundis C, Sarkozy A, Levinstein M, Sieira J,
Baltogiannis G, Di Giovanni G, Ciconte G, Casado-Arroyo R, Saitoh Y, Brugada P. Europace. 2014
Apr;16(4):528-32. doi: 10.1093/europace/eut309. Epub 2013 Oct 9. PMID: 24108229
▪ Life-threatening ventricular arrhythmias during ajmaline challenge in patients with Brugada
syndrome: incidence, clinical features, and prognosis. Conte G, Sieira J, Sarkozy A, de Asmundis
C, Di Giovanni G, Chierchia GB, Ciconte G, Levinstein M, Casado-Arroyo R, Baltogiannis G,
Saenen J, Saitoh Y, Pappaert G, Brugada P. Heart Rhythm. 2013 Dec;10(12):1869-74.
▪ Safe single-dose administration of propofol in patients with established Brugada syndrome: a
retrospective database analysis. Flamée P, De Asmundis C, Bhutia JT, Conte G, Beckers S,
Umbrain V, Verborgh C, Chierchia GB, Van Malderen S, Casado-Arroyo R, Sarkozy A, Brugada P,
Poelaert J. Pacing Clin Electrophysiol. 2013 Dec;36(12):1516-21.
▪ Impact of transseptal puncture site on acute and mid-term outcomes during cryoballoon ablation: a
comparison between anterior, medial and posterior transatrial access. Chierchia GB, CasadoArroyo R, de Asmundis C, Rodriguez-Manero M, Sarkozy A, Conte G, Sieira J, Levinstein M,
Baltogiannis G, di Giovanni G, Overeinder I, Ocello S, Rosas E, Isola F, Brugada P. Int J Cardiol.
2013 Oct 9;168(4):4098-102.
▪ Phrenic nerve paralysis during cryoballoon ablation for atrial fibrillation: a comparison between the
first- and second-generation balloon. Casado-Arroyo R, Chierchia GB, Conte G, Levinstein M,
Sieira J, Rodriguez-Mañero M, di Giovanni G, Baltogiannis Y, Wauters K, de Asmundis C, Sarkozy
A, Brugada P. Heart Rhythm. 2013 Sep;10(9):1318-24.
▪ Myocardial delayed enhancement by magnetic resonance imaging in a patient with Duchenne
muscular dystrophy and ventricular tachycardia. Rodríguez-Mañero M, Sarkozy A, Tanaka K,
Casado-Arroyo R, Brugada P. Acta Cardiol. 2013 Jun;68(3):343-4. No abstract available.
▪ Cryoballoon ablation as index procedure for paroxysmal atrial fibrillation: long-term results from a
single center early experience. Rao JY, Chierchia GB, de Asmundis C, Casado-Arroyo R,
Overeinder I, Sarkozy A, Paparella G, Capulzini L, Sorgente A, Rodriguez-Manero M, Ricciardi D,
Namdar M, Brugada P. J Cardiovasc Med (Hagerstown). 2014 Mar;15(3):194-8.
▪ Simultaneous wide and narrow QRS complex tachycardia: what is the mechanism? RodríguezMañero M, Bayrak F, Namdar M, Casado-Arroyo R, Ricciardi D, Chierchia GB, Sarkozy A, de
Asmundis C, Brugada P. Rev Port Cardiol. 2013 May;32(5):431-5.
▪ Optimizing the use of aspirin for cardiovascular prevention. Casado-Arroyo R, Sostres C, Lanas A.
Drugs. 2013 Jun;73(8):803-14.
▪ Letter: the burden of co-morbidity in the population contributes more to upper gastrointestinal
bleeding than aspirin--authors' reply. Lanas A, Polo-Tomás M, Casado-Arroyo R. Aliment
Pharmacol Ther. 2013 Jun;37(11):1116.
▪ Repeat procedure using radiofrequency energy for recurrence of atrial fibrillation after initial
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Ruben Casado Arroyo
cryoballoon ablation: a 2-year follow-up. Conte G, Chierchia GB, Sieira J, Levinstein M, CasadoArroyo R, De Asmundis C, Sarkozy A, Rodriguez-Manero M, Di Giovanni G, Baltogiannis G,
Wauters K, Brugada P. Europace. 2013 Oct;15(10):1421-5.
▪ The aspirin cardiovascular/gastrointestinal risk calculator--a tool to aid clinicians in practice. Lanas
A, Polo-Tomás M, Casado-Arroyo R. Aliment Pharmacol Ther. 2013 Apr;37(7):738-48.
▪ Pulmonary vein intramural hematoma as a complication of cryoballoon ablation of paroxysmal atrial
fibrillation. Conte G, Chierchia GB, Casado-Arroyo R, Ilsen B, Brugada P. J Cardiovasc
Electrophysiol. 2013 Jul;24(7):830-1.
▪ Atrial fibrillation outcomes: changing the paradigm. Casado-Arroyo R, Chierchia GB, RodriguezMañero M, Levinstein M, Namdar M, Conte G, Sieira J, Sarkozy A, de Asmundis C, Wauters K,
Brugada P. Int J Cardiol. 2013 Jun 20;166(2):545-7.
▪ Prevalence, clinical characteristics and management of atrial fibrillation in patients with Brugada
syndrome. Rodríguez-Mañero M, Namdar M, Sarkozy A, Casado-Arroyo R, Ricciardi D, de
Asmundis C, Chierchia GB, Wauters K, Rao JY, Bayrak F, Van Malderen S, Brugada P. Am J
Cardiol. 2013 Feb 1;111(3):362-7.
▪ The choreography of the intermittent electrocardiographic Brugada pattern from beat to beat.
Casado-Arroyo R, Rodriguez-Mañero M, Brugada P. Eur Heart J. 2012 Nov;33(21):2633.
▪ The usefulness of the consensus clinical diagnostic criteria in Brugada syndrome. Sarkozy A,
Paparella G, Boussy T, Casado-Arroyo R, Yazaki Y, Chierchia GB, De Asmundis C, Bayrak F,
Namdar M, Richter S, Brugada J, Brugada P. Int J Cardiol. 2013 Sep 10;167(6):2700-4.
▪ Verification of pulmonary vein isolation during single transseptal cryoballoon ablation: a comparison
between the classical circular mapping catheter and the inner lumen mapping catheter. Chierchia GB,
Namdar M, Sarkozy A, Sorgente A, de Asmundis C, Casado-Arroyo R, Capulzini L, Bayrak F,
Rodriguez-Mañero M, Ricciardi D, Rao JY, Overeinder I, Paparella G, Brugada P. Europace. 2012
Dec;14(12):1708-14.
Angina and origin of three major coronary arteries from independent ostia in right coronary sinus.
Linares Vicente JA, Ruiz Arroyo JR, Casado Arroyo R. Anadolu Kardiyol Derg. 2012
Aug;12(5):438-40.
▪ Balancing the risk and benefits of low-dose aspirin in clinical practice. Casado-Arroyo R, Gargallo
C, Lanas Arbeloa A. Best Pract Res Clin Gastroenterol. 2012 Apr;26(2):173-84.
▪ Role of ASA in the primary and secondary prevention of cardiovascular events. Casado-Arroyo R,
Bayrak F, Sarkozy A, Chierchia GB, de Asmundis C, Brugada P. Best Pract Res Clin
Gastroenterol. 2012 Apr;26(2):113-23.
▪ Lower GI bleeding is more common than upper among patients on dual antiplatelet therapy:
longterm
follow-up of a cohort of patients commonly using PPI co-therapy. Casado Arroyo R, PoloTomas M, Roncalés MP, Scheiman J, Lanas A. Heart. 2012 May;98(9):718-23.
▪ Letter by Casado-Arroyo et al regarding article, "Electrocardiographic characteristics and SCN5A
mutations in idiopathic ventricular fibrillation associated with early repolarization". Casado-Arroyo R,
Rodriguez-Mañero M, Sarkozy A, Brugada P. Circ Arrhythm Electrophysiol. 2012 Apr;5(2):e59;
author reply
▪ The apple does not fall far from the tree: epicardial ventricular tachycardia due to blunt chest
trauma. Casado-Arroyo R, Namdar M, Bayrak F, Sarkozy A, Meir ML, Brugada P. Eur Heart J.
2012 Jun;33(12):1430.
▪ Pulmonary vein isolation during cryoballoon ablation using the novel Achieve inner lumen mapping
catheter: a feasibility study. Chierchia GB, de Asmundis C, Namdar M, Westra S, Kuniss M,
Sarkozy A, Bayrak F, Ricciardi D, Casado-Arroyo R, Rodriguez Manero M, Rao JY, Smeets J,
Brugada P. Europace. 2012 Jul;14(7):962-7.
8/8/16
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Curriculum vitae
Ruben Casado Arroyo
▪ [Antiplatelet agents and proton pump inhibitors. How can the risk-benefit balance be optimized in
patients at risk for cardiovascular disease and gastrointestinal bleeding?]. Casado-Arroyo R,
Muñoz-Villalenguas M, Lanas Arbeloa A. Gastroenterol Hepatol. 2011 Aug-Sep;34(7):478-91.
▪ The value of a family history of sudden death in patients with diagnostic type I Brugada ECG
pattern. Sarkozy A, Sorgente A, Boussy T, Casado R, Paparella G, Capulzini L, Chierchia GB,
Yazaki Y, De Asmundis C, Coomans D, Brugada J, Brugada P. Eur Heart J. 2011 Sep;32(17):215360.
▪ Cardiac biomarker response to intermittent exercise bouts. Carranza-García LE, George K,
Serrano-Ostáriz E, Casado-Arroyo R, Caballero-Navarro AL, Legaz-Arrese A. Int J Sports Med.
2011 May;32(5):327-31.
▪ Underutilization of gastroprotection for at-risk patients undergoing percutaneous coronary
intervention: Spain compared with the United States. Casado-Arroyo R, Scheiman JM, Polo-Tomas
M, Saini SD, Del Rio A, Guastello E, Lanas A. Aliment Pharmacol Ther. 2010 Sep;32(5):689-95.
▪ [Symmetrical peripheral gangrene and disseminated intravascular coagulation associated with
pneumococcal sepsis]. Suárez-Amor O, Casado-Arroyo R, Cabanillas M, Labandeira J, Toribio J.
Actas Dermosifiliogr. 2009 May;100(4):334-5.
▪ CT and MR imaging findings in methanol intoxication. Blanco M, Casado R, Vázquez F, Pumar JM.
AJNR Am J Neuroradiol. 2006 Feb;27(2):452-4.
▪ [Autoimmune hemolytic anemia as presentation form of systemic lupus erythematosus]. Casado
Arroyo R, Lado Lado FL, Rodríquez Constenla I, Rodríguez López I. An Med Interna. 2003
Sep;20(9):499.
Projects
Memberships
- European Society of Cardiology.
- Belgium Society of Cardiology.
- Spanish Society of Cardiology.
- Spanish Society of Intensive Care.
Other Relevant Information
Certifications:
Certified in Cardiac Pacing and Electrophysiology- European Society of Cardiology.
Certified in Transesophageal Echocardiography- European Society of Cardiology.
Other Certifications:
Investigator Site Personnel ICH-GCP training on March 8, 2014
Honours and awards:
Horlait–Dapsens award 2014.
PhD Thesis Award: University of Zaragoza, 2014
8/8/16
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