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Practice Test Chapter 12
Name___________________________________
MULTIPLE CHOICE. Choose the one alternative that best completes the statement or answers the question.
1) Where do the microtubules of the spindle originate during mitosis in both plant and animal cells?
A) chromatid
B) centrosome
C) centriole
D) kinetochore
E) centromere
1)
2) The formation of a cell plate is beginning across the middle of a cell and nuclei are re-forming at
opposite ends of the cell. What kind of cell is this?
A) an animal cell undergoing cytokinesis
B) a plant cell in metaphase
C) an animal cell in telophase
D) a plant cell undergoing cytokinesis
E) an animal cell in metaphase
2)
3) Which of the following are primarily responsible for cytokinesis in plant cells?
A) centrioles and basal bodies
B) actin and myosin
C) kinetochores
D) Golgi-derived vesicles
E) cyclin-dependent kinases
3)
4) Chromosomes first become visible during which phase of mitosis?
A) prophase
B) anaphase
C) telophase
D) metaphase
E) prometaphase
4)
5) During which phases of mitosis are chromosomes composed of two chromatids?
A) from G1 of interphase through metaphase
5)
B)
C)
D)
E)
from interphase through anaphase
from metaphase through telophase
from anaphase through telophase
from G2 of interphase through metaphase
6) Movement of the chromosomes during anaphase would be most affected by a drug that
A) increases cyclin concentrations.
B) reduces cyclin concentrations.
C) prevents attachment of the microtubules to the kinetochore.
D) prevents shortening of microtubules.
E) prevents elongation of microtubules.
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6)
7) The somatic cells derived from a single-celled zygote divide by which process?
A) meiosis
B) replication
C) mitosis
D) binary fission
E) cytokinesis alone
7)
8) Imagine looking through a microscope at a squashed onion root tip. The chromosomes of many of the
cells are plainly visible. In some cells, replicated chromosomes are aligned along the center (equator)
of the cell. These particular cells are in which stage of mitosis?
A) telophase
B) metaphase
C) prophase
D) prometaphase
E) anaphase
8)
9) In order for anaphase to begin, which of the following must occur?
A) Cohesin must be cleaved enzymatically.
B) Kinetochores must attach to the metaphase plate.
C) Spindle microtubules must begin to depolymerize.
D) Chromatids must lose their kinetochores.
E) Cohesin must attach the sister chromatids to each other.
9)
10) If mammalian cells receive a go-ahead signal at the G1 checkpoint, they will
A)
B)
C)
D)
E)
10)
complete cytokinesis and form new cell walls.
move directly into telophase.
exit the cycle and switch to a nondividing state.
show a drop in MPF concentration.
complete the cycle and divide.
11) Cells that are in a nondividing state are in which phase?
A) G2
B) G0
C) G1
11)
D) S
E) M
12) Which of the following is a protein synthesized at specific times during the cell cycle that associates
with a kinase to form a catalytically active complex?
A) Cdk
B) MPF
C) protein kinase
D) cyclin
E) PDGF
12)
13) This is the shortest part of the cell cycle:
A) M
B) G0
13)
C) G2
14) DNA is replicated at this time of the cell cycle:
A) S
B) G1
C) G0
D) S
E) G1
D) M
E) G2
14)
2
15) The MPF protein complex turns itself off by
A) exiting the cell.
B) activating a process that destroys cyclin component.
C) activating an enzyme that stimulates cyclin.
D) binding to chromatin.
E) activating the anaphase-promoting complex.
15)
16) Vinblastine is a standard chemotherapeutic drug used to treat cancer. Because it interferes with the
assembly of microtubules, its effectiveness must be related to
A) myosin denaturation and inhibition of cleavage furrow formation.
B) inhibition of regulatory protein phosphorylation.
C) disruption of mitotic spindle formation.
D) suppression of cyclin production.
E) inhibition of DNA synthesis.
16)
17) The drug cytochalasin B blocks the function of actin. Which of the following aspects of the cell cycle
would be most disrupted by cytochalasin B?
A) cleavage furrow formation
B) spindle formation
C) cell elongation during anaphase
D) spindle attachment to kinetochores
E) DNA synthesis
17)
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