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10/30/2012 Diagnosing the Out of Control Pre-Schooler Barbara J. Howard, MD bhoward@chadis com [email protected] www.CHADIS.com I & my spouse have the following financial relationship with the manufacturer of any commercial product and/or provider of commercial services discussed in this CME activity: CHADIS The Center for Promotion of Child Development through Primary Care and its for-profit subsidiary, Total Child Health, Inc. developed CHADIS, a web-based screening and dd decision i i supportt system. t D Dr. H Howard d iis P President id t and d she and her spouse Dr. Sturner are members of the Board of Directors of the for-profit subsidiary, Total Child Health. Dr. Sturner is Director of the Center and both are members of its Board of Directors. They are paid consultants to both entities. The terms of the arrangement are being managed by The Johns Hopkins University in accordance with its conflict of interest policies. I do not intend to discuss an unapproved/investigational use of a commercial product/device in my presentation. Learning Objectives What is normal opposition? Pediatricians will be able to develop a differential diagnosis for the out of control child Pediatricians will be able to carry out steps to discover the “meaning” of children’s behavior Autonomy develops over time Directs/averts gaze at birth Initiate “dialogue” by 8 weeks Hatching at 8 months Resist object pull- 8 months Demand D d exclusive l i care off mo Tantrums by 12 months Separate easily by 4 years “Identity” develops as teen Assertion versus Aggression Degree of dysfunction determines whether behaviors are normal or abnormal Standing Oppositionality Common 2-16% of children Presents as: He won’t listen Not minding Doing the opposite of what I say Have to tell her a hundred times Typical compliance of preschoolers 60%; Noncompliant children often 30% Boys > Girls until puberty then = Onset usually < age 8 att 9 months th up for having their needs met Definitions V65.4 Aggressive/Oppositional Variationseveral x per wk, min impact V71.02 V71 02 Aggressive/Oppositional ProblemProblem begins to effect, mod. impact 313.81 Oppositional Defiant Disorder 1 10/30/2012 313.81 Oppositional Defiant Disorder– DSM V def. pending A persistent pattern of angry and irritable mood along with defiant and vindictive behavior as evidenced by >=4 of the following symptoms being displayed with >=1 person other than siblings. A. Angry/Irritable Mood 1. Loses temper 2. Is touchy or easily annoyed by others. 3 Is angry and resentful 3. B. Defiant/Headstrong Behavior 4. Argues with adults 5. Actively defies or refuses to comply with adults’ request or rules 6. Deliberately annoys people 7. Blames others for his or her mistakes or misbehavior C. Vindictiveness 8. Has been spiteful or vindictive >=2x within 6 months Anger “A strong feeling of displeasure or hostility” Aggression – intrusive actions against others or acts intended to hurt others “Frustration->Aggression” hypothesis People respond with anger because they feel helpless to fix how they feel. A B. Also under DSM 5 consideration A. The persistence and frequency should be used to distinguish normal from symptomatic to determine disorder. <5 years: most days for a period of at least six months >5 years: at least once per week for at least six months B Other factors to consider: developmental level B. level, gender gender, and culture. C. Causes clinically significant impairment in social, educational, or vocational activities. D. The behaviors may be confined to only one setting or, in more severe cases, present in multiple settings Why is anger mgt important? Those who have failed to master the early regulatory tasks are more likely to develop: p Conduct problems Peer-rejection Poor school performance Unhappy lives universal emotion Hard on everyone around them (Strain, Kerr, Stagg & Lenkner, 1984). Prevalence of Aggressive Behavior in Young Children 15-30% of preschoolers have significant behavior problems, usually incl. aggression 25-40% boys 2-5 yrs mod to high aggression 10 28% girls 10-28% il 2 2-5 5 yrs mod d tto hi high h aggression i Aggression typically peaks before age 3 years Some Societal Trends Potentially Increasing Aggression 64% of mothers work FT while child <1 yr Lower income families get poorer child care Television violence is modeled > 15 months Father presence modulates aggression Lack of sleep is rampant in children and parents 2 10/30/2012 Environment of Anger: Parent factors Caregivers themselves have: Anger can be evoked by: 1))Environment of anger g 2)Painful feelings 3) Thwarting of a perceived need Painful feelings in Child -> anger or hunger or fatigue or med effects Failure of mastery Life stress beyond their coping ability Poverty, housing, immigration, legal problems, discrimination Lack of social support Marital discord/divorce (45%) Domestic or neighborhood violence Depression (30-50% with kids <5), anxiety or other mental health issues eg ADHD in 25% pa of kids with ADHD Health problems with worry, pain, disability, exhaustion Substances: prescribed, alcohol 6%, drugs, caffeine Exhaustion, sleep debt Frustration Pain Pain Low self-esteem Failure socially Loneliness L li Isolation Anxiety about situations over which the child has no control including sensory issues Failure of support Dependency needs not met Sadness/depression- “Better mad than sad” Problems of Physical Punishment Impulsive, poorly modulated, inconsistent Disrespectful to child, lowers self esteem Increases aggression, sibling rivalry Not educational Replaces other forms of management Not useful at older ages, long term Produces fear and anger, inhibits other behavior Associated with later depression, alcoholism, drug abuse, lower school/job achievement, less stable marriages, spouse abuse, child abuse Illness eg Sickle cell, arthritis, eczema, IBD, constipation Injuries eg head injury and headache Abuse - Physical, emotional or sexual Corporal punishment Rates of Corporal Punishment in US 25% 1-6 months 50% 6-12 months 90% 3 years 60% 10-12 40% 14 25% 17 3 10/30/2012 Hunger in Children in the United States: Potential Behavioral and Emotional Correlates Thwarting of perceived needs Ronald E. Kleinman*, , J. Michael Murphy§, , Michelle Little§, Maria Pagano§, Cheryl A. Wehler¶, Kenneth Regal#, and Michael S. Jellinek§, 8% of US children <12 years classified as hungry Pediatric Symptom Checklist showed that virtually all behavioral, emotional, and academic problems were more prevalent in hungry children, but that aggression and anxiety had the strongest degree of association with experiences of hunger. Needs of Children Need for state regulation Need for mastery Need for positive emotional tone Need for assistance regulating negative affect Need to be taught prosocial behavior and empathy Need for fair treatment Patterns of Parenting Dysfunction Over regulation Under regulation Inappropriate regulation Chaotic regulation Affective Mismatch Perceptive caregivers recognize needs of the child Connected parents know their children well, so they are less likely to create situations that provoke anger. Confident parents know they don't have to be harsh to be in control. The unconnected child feels something important is missing in his “self” and is angry about it. Well being is threatened. Under regulation - factors Too busy… ?cell phones Guilty for absence Vulnerable child syndrome History of abuse/harsh parenting Mood disorder in parent Substance use by parent(s) Marital discord 4 10/30/2012 Over regulation Needs of Children Intrusive management- Need for state regulation Need for mastery Need for positive emotional tone Need for assistance regulating negative affect Need to be taught prosocial behavior and empathy Need for fair treatment May be from parental anxiety, cultural, “vulnerable child” Excessively harsh punishment 1) Constantly "being yelled at" for even minor behavior (Nattering) 2) No attention/reinforcement for good behavior 3) Corporal punishment Possible effects Anger, opposition back to their apparently “mean” parent. Low self esteem Pay The Need for State Regulation Attention/Impulsivity Routines of eating, sleep Consistent responsiveness These stabilize mood, reduce resistance Avoid overstimulation- noise, awake time, sex Especially important for temperamentally irregular, unadaptable children Especially vulnerable- CNS damaged, lead poisoned, prenatal substance exposed, ADHD Likely missing in social chaos, overextended Attention/impulsivity problems commonly associated with anger/aggression. Up p to 60% of children with oppositional pp behavior have ADHD. Consider side effects of medications used Preschool ADHD Diagnosis Preschool ADHD Treatment Study (PATS) DSM-5 requires onset < 12 years Most had symptoms at 3-4 years (Eggar) Broad differential diagnosis Preschoolers more environmentally sensitive DX: (1) symptoms >=9 months (2) dysfunction in both home and other settings such as preschool or child care, (3) dysfunction that has not responded adequately to behavior therapy. 303 preschoolers (3-5.5 years) with moderate to severe ADHD 8-phase, 70-week c two double-blind, controlled phases, a crossover-titration trial followed by a placebo-controlled parallel trial & 10 mo f/u 69.6% c co-morbid disorders: ODD, anxiety, communication disorders Those c communication disorders more anxious and depressed. ADHD severity correlated c internalizing disorders and lower functioning. 5 10/30/2012 Preschool ADHD Harvard study of 4-6 year olds coming to child psychiatry clinic 86% 68% had ADHD had 2 or more mental health disorders 40% resolve ADHD with age >50% persist: more if earlier onset, family history of ADHD. More comorbidities, less responsive to medications (MPH) than older kids c ADHD. Needs of Children Regulation Disorders of Sensory Processing (DC: 0-3R; Zero to Three, 2005) Three Features: (1) (2) (3) sensory processing difficulties, motor difficulties, and a specific behavioral pattern Types Hypersensitive Type A: Fearful/Cautious Hypersensitive Type B: Negative/Defiant Hyposensitive/Underresponsive Sensory Stimulation-Seeking/Impulsive The Need for Mastery Need for state regulation Need for mastery Need for positive emotional tone Need for assistance regulating negative affect Need to be taught prosocial behavior and empathy Need for fair treatment Experiences Developmental difference Qualities of Good Child Care Won’t do or Can’t do? Use a standard developmental screen for: developmental delay low cognitive functioning learning disabilities speech/language delay social learning disability Sensory integration problem Autism Spectrum Disorder of mastery should respect need for autonomy but avoid overwhelming child Stress of separation p for day y care can evoke anger (dependency need) Over protectiveness or over strictness evoke anger (autonomy need) Inconsistency evokes anger (fairness) Inadequate limits evoke anger (anxiety) Adequate caregiver:child ratios Attention to positive behavior Anticipation of problems and redirection Adequately stimulating curriculum Space and toys for small group play Nonphysical discipline Lower income child gets lower quality 6 10/30/2012 Needs of Children Need for state regulation Need for mastery Need for positive emotional tone Need for assistance regulating negative affect Need to be taught prosocial behavior and empathy Need for fair treatment Hostile Bias Attribution Tendency to infer hostile intent in others May stem from: Past adverse experiences attachment Cognitive bias Mood disorder Insecure Need for Positive Emotional Tone Positive tone & stable attachment avoid suspiciousness & enhance resilience under stress which can evoke anger Hostility in the family: raises tension aggression includes pain/fear which evokes anger models Depressed child &/or adult need treatment Anxious children may over infer aggressive intent & over react Reaction to stressful environment Inconsistent/strenuous or irregular schedules make children vulnerable to aggressive gg behaviors due being g tired,, hungry, or stressed by irregular, unusual demands. Tend to act aggressively proactively Traumatic Life Events Feel badly about themselves Children viewing violence may model it Children with a traumatic experience may feel guilty and act up to elicit punishment Family members experiencing trauma may change their parenting Include sexual traumas esp with older child Trauma changes the brain/reactions If told they are bad, will act the part Reassure: "You're not bad, you're just young and young people sometimes do young, foolish things. Promise adult’s help: “I will help you stop doing them so you will grow up feeling like you are the nice person I know you are.” 7 10/30/2012 Needs of Children for state regulation Need for mastery Need for positive emotional tone Need for assistance regulating negative affect Need to be taught prosocial behavior and empathy Need for fair treatment The Need for Assistance Regulating Negative Affect Need Environment reinforcing anger Sometimes a child's anger prompts an adult to set rules more clearly, explain matters more thoroughly, g y, or make changes g in the child's environment. Child learns that anger is an all-purpose red flag for help Especially if lesser signals don’t work Mood Disorders Remember that young children may not report sadness. Normal predominant child mood is cheerful D Depression i may presentt as h hyperactivity ti it or irritability. Rapid mood swings may be bipolar Family history of mood often suggestive “Coercive Cycle” where child anger results in parent backing off Anxiety and Anger Anxiety produces vigilance for threat High levels of arousal->readiness for fight/flight May be combined with ADHD and impulsivity or depression Proactive aggression is one coping strategy May justify aggression with anger Regulation occurs through: jollying, distracting, modeling, acknowledging, verbalizing, g, compromising p g Depression/temperament can be source of anger Excessive negative affect is encouraged by: covert encouragement eg projection, passive avoidance, punishment. These are likely when parents can’t tolerate negative feelings. Needs of Children Need for state regulation Need for mastery Need for positive emotional tone Need for assistance regulating negative affect Need to be taught prosocial behavior and empathy Need for fair treatment 8 10/30/2012 The Need to Be Taught Prosocial Behavior and Empathy Skills include: trading, taking turns, waiting, asking for things, thanking, taking other’s point of view seeing effects of own actions view, actions, recognizing feelings of others Less taught/modeled if excess stress as in: large family size low income single parenthood Need for Fairness Children have an inherent sense of Justice Sibling rivalry related mostly to “perception of differential treatment” Sibling g may y have special p needs Needs of Children Need for state regulation Need for mastery Need for positive emotional tone Need for assistance regulating negative affect Need to be taught prosocial behavior and empathy Need for fair treatment Meaning of the Behavior Child behavior has meaning to the child and family and is initiated and/or maintained by y this meaning. g Caregivers may be erratic or truly unfair Child may feel at unfair disadvantage: Misunderstood Outpaced in the group Unable to perform to own standards due to perfectionism A,B,C of Behavior Antecedent- setting events: what was going on prior? Behavior- what exactly did she do? Consequence- what resulted for child and for parent? (reinforcement, feelings) Ask child: What do you think your parents should do? “Activities of Daily Living” Examples Ask about: meal times, bedtime (needs structure) eating, toileting (needs autonomy) separation, ti fears f (needs ( d emotional ti l development and security) peers, school (needs competence) OR “Tell me about a typical day starting when he gets up…” 9 10/30/2012 Sleep debt Average Sleep by Age Age 18 mo 2-3 yr 4-6 yr 7-11yr 12-18yr Destabilizes frontal lobe Worsens all mood disorders Parent with sleep debt is more irritable Get sleep diary if necessary Consider Obstructive Sleep Apnea Work on sleep first or simultaneously Example: Meal times- Nighttime Daytime 11.5 2.0 11.0-11.5 1.0-1.5 10.75-11.5 9.5-10.5 8.25-9.25 Components of Assessment History from child and parents Physical exam- abuse, syndrome, neuro Vision and hearing Developmental D l t l screen or assessmentt Checklists from daycare or teachers Relevant lab- eg lead, Hgb, sleep study Observation of parent-child interaction Hypotheses and trial of intervention Won’t come, won’t sit, throws food, hits sibs -> ADHD, attention getting R f Refuses ttextures, t very picky, i k chokesh k > regulatory/sensory integration Parent insists on eating/manners-> over control Differential Diagnosis -ages 3-6 years Most common Inappropriate expectations/mgt Difficult Temperament Sleep deprivation Stressful environment ADHD Differential Diagnosis - 3-6 yrs Less common Hearing problem PTSD Mood Disorder incl. bipolar Mixed Expressive/Receptive Language Disorder Low cognitive functioning Learning Disability/Difference Regulatory/Sensory Integration Problem Autism Spectrum Disorders: Autism, Pervasive Developmental Disorder, Asperger’s 10 10/30/2012 Medical History- especially… Risk factors for developmental disabilities plus Pain Hunger Anemia/ iron deficiency Celiac disease ADHD Mood Sleep disorder Family History Any “health or emotional or learning problems” Include substance use Educational/vocational attainments Looking for: ADHD, mood, juvenile delinquency, LD History from Child • • School, teacher, friends, bullies Best friend, age, activities Who lives at home? Nice/mean, best/hardest parts from child What do your parents do if you do something bad? Has anything bad or scary happened? (trauma) Social History from Parents Hardest and best parts? Do you agree on discipline? Who can you count on? How is the marriage? “Who does he take after?” (projection) Intervention for Diagnosis Formulate a hypothesis Negotiate a plan Follow up Failure Children who feel more loved, accepted and competent are less angry! is as telling as success 11 10/30/2012 Tools to help in this process Ages & Stages Questionnaires®– SocialEmotional (ASQ:SE) J Squires, D Bricker, & E Twombly Age range: 6–60 months General areas screened: Personal-social (self-regulation, compliance, communication, adaptive functioning, autonomy, affect, and interaction with people) Questionnaires for ages 6 6, 12 12, 18 18, 24 24, 30 30, 36 36, 48 48, and 60 months months, Parents/caregivers complete questionnaires; 5-6 grade reading Takes 10–15 min to complete; 1-3 minutes to score Validity and reliability: n>3,000 across the age intervals and their families. Reliability is 94%; validity is between 75% and 89% English and Spanish ASEBA Child Behavior Checklist 1.5-5 1.5-5 years Caregiver and teacher forms; 15-20 min; multiple languages 99 items concerning issues, disabilities, descriptions of problems about the child being rated, and the best things about the child being rated. Emotionally Reactive, Anxious/Depressed, Somatic p , Withdrawn,, Attention Problems,, Aggressive gg Complaints, The three primary scales (Internalizing, Externalizing, Total Problems) plus Sleep Problems syndrome. DSM scales: Affective Problems; Pervasive Developmental Problems; Anxiety Problems; Oppositional Defiant Problems; Attention Deficit/Hyperactivity Problems Includes Language Development Survey (LDS) indicating whether a child's vocabulary and word combinations are delayed relative to norms for ages 18-35 months. Based on ratings of 1,728 children; normed on 700. Automated scoring program available CHADIS 0-3 Brief Infant-Toddler Social & Emotional Assessment (BITSEA) Symptom checklist for 1-2 year olds 12-36 months 60 items; 10 min alphas=.83 for problem scale and .66 for competence scale vs ITSEA Tested on 1280 parents, fairly diverse both ethnically and SES Test-retest .72-.82; good sensitivity & specificity (Albus, Sturner, Howard, Egger, Emde, Thomas, Wise, 2009) Collects data on daily routines and functioning e.g eating, sleeping Assesses all DC: 0-3R diagnostic criteria, incl: traumatic stress disorder; anxiety disorders; grief; mixed disorder of emotional expressiveness; adjustment disorder; regulatory disorders; sleep disorders; eating disorders; and disorders of relating and communicating. Translation of DC: 0-3R diagnostic descriptions into definable criteria by concensus; where specific guidelines in DC: 0-3R, these were utilized. Where no specific DC: 0-3R 0 3R guidelines but comparable disorders in the DSM-IV or DSM-PC, effort to be consistent. Modeled after DSM-PC categories of “variation,” “problem” and “disorder,” based on degree of disruption of child and family life and/or # symptoms endorsed, as appropriate. Focus also on assets Ages 2 months- 4 years Takes 10-30 min depending on concerns endorsed Test-retest reliability satisfactory Validity vs BITSEA, ITQ, CBCL, PAPA underway n=450 Eyeberg Child Behavior Inventory Screens general behavior 2 to 11 y (best used to age 4) 36 items; 7 min C score >16 Cut 16 Externalizing problems (eg, conduct, attention, aggression) Sensitivity 80%, specificity 86% 12 10/30/2012 Behavior Assessment System for Children (BASC) Comprehensive behavior rating scales Ages: 2:6-18; self report 8-18 10-20 min;; 30-45 minutes ((SRP)) Parent, teacher, youth, devel. history, structured observation versions T scores, % by gender and age & a clinical population Strengths and Difficulties QuestionnaireGoodman Screen of burdensome behavior: conduct, attention, anxiety-depression Ages 4-16;33 items As good as CBCL for conduct and emotional problems, bl better b tt for f ADHD Burden item highly related to use of mental health services Standardized in several countries, Free; available in >40 languages Computer scoring Tools in CHADIS INFANT & YOUNG CHILD Questionnaires®, Ages & Stages Third Ed. (ASQ3™) Modified Checklist for Autism in Toddlers (MCHAT) & Follow-up CHADIS 0-3 (young child mental health) ASQ-SE SCHOOL AGE Pediatric Symptom Checklist (17 items) Vanderbilt Parent Revised & Follow-up CHADIS - DSM Strengths & Difficulties Questionnaires & FA SCARED: Parent and Child Child Behavior Checklist (coming) ADOLESCENT GENERAL HEALTH CHADIS Visit Priorities Early Periodic Screening Diagnosis and Treatment (EPSDT) Family Medical History Family Cardiac History Safety & Guidance Topics (Bright Futures) Edinburgh Postnatal Depression Scale Multidimensional Scale of Perceived Social Support (MSPSS) McMaster Family Assessment Device, General Functioning Scale CHADIS Stressors Checklist Adverse Childhood Experiences (ACE) Partner Violence Screen 2-PRIME adult depression Safe Environment for Every Kid CHAMPS (Adolescent Risk Behaviors) QUALITY MONITORING TEACHER DATA Vanderbilt Teacher Revised & Follow Up School Intervention Questionnaire psychosocial screen Ages 4-16 Child form >9 35 items,, 7 min One page parent questionnaire Free, English and Spanish Cutoffs but no standard scores Sensitivity (80% to 95%), but somewhat scattered specificity (68% to 100%). CHADIS decision support: Parent and teen separately take previsit online questionnaires Clinician reviews results, can consult linked textbook Clinician may exchange findings with school or mental health provider online Clinician finds relevant resources, handouts from links & prints for family Education materials automatically populate MemoryBook/CarePortal Diagnostic Classification 0-3R FAMILY / ENVIRONMENT General (partial listing) Pediatric Symptom Checklist - Youth Patient Health Questionnaire 9 (PHQ-A) CRAFFT Kutcher Adolescent Depression Scale CES-DC (depression) Pediatric Symptom Checklist- Jellinek Provider-level Promoting Healthy Development Survey Child-Adolescent Needs & Strengths (CANS) 13 10/30/2012 Hypersensitive Type A: Fearful/Cautious Hypersensitive Type B: Negative/Defiant Sensory Reactivity Patterns: overreactivity to sensory stimuli, including light touch, loud noises, bright lights, unfamiliar smells and tastes, rough textures, or movement in space. Motor Patterns ((>=1) 1) Difficulties with postural control and tone Difficulty in fine motor coordination Difficulty with motor planning Less exploration than expected for age Limited sensory-motor play Behavioral Patterns: excessive cautiousness, inhibition, and fearfulness Hyposensitive/Underresponsive Sensory Reactivity Patterns Underreactivity to sounds, movement, smell, taste, touch, and proprioception In infants, lack of responsivity to sensations and social overtures Sensory Stimulation-Seeking/Impulsive Sensory Reactivity Patterns Motor Patterns (>=2) Limited exploration Restricted play repertoire Search for sensory input, often repetitive Lethargy Poor motor planning and clumsiness Behavioral Patterns (>=1) Apparent lack of interest in exploring properties of objects, playing challenging games, or engaging in social interactions Apathetic appearance Fatigability Withdrawal from stimuli Inattentiveness May appear delayed or depressed. Selected references Barkley RA. Defiant Children: A clinician's manual for assessment and parent training. NY, Guilford Press, 1997 Barkley RA, Benton C, Your Defiant Child, The Guilford Press,, NY,, 1998 Christophersen, E.R. & Mortweet, S.L. (2003). Parenting that Works: Building Skills that Last a Lifetime. Washington D.C.: APA Books Christophersen, E.R. (2003). Part of the Relationships APA Psychotherapy Video Series, Washington, D.C.: American Psychological Association. Parenting Young Children Sensory reactivity patterns are identical to those of Type A Motor Patterns are also identical to those described in Type A: Fearful/Cautious Behavioral patterns: avoid or be slow to engage & aggressive only when provoked. Negativistic N ti i ti b behavior... h i ((one or more off the th following) f ll i ) Controlling behaviors (For children older than 12 months: Defiance Preference for repetition, absence of change, and, if change is necessary, change at a slow pace Difficulty adapting to changes in routines or plans (one or both of the following) Compulsiveness and perfectionism Avoidance or slow engagement in new experiences or sensations Craving for high-intensity sensory stimuli. Such a craving may lead to destructive or high-risk behaviors Motor Patterns (>=1) High need for motor discharge Diffuse impulsivity p y Accident proneness without clumsiness Behavioral Patterns (>=1) High activity levels Seeking constant contact with people and objects Seeking stimulation through deep pressure Recklessness Disorganized behavior as a consequence of sensory stimulation Gordon T. Parent Effectiveness Training, NY, Peter H. Wyden, Inc. 1970 Ghuman JK, et al. Comorbidity moderates response to methylphenidate in the Preschoolers with AttentionDeficit/Hyperactivity Disorder Treatment Study (PATS). J Child Adolesc Psychopharmacol. 2007 Oct;17(5):563-80. Greene R, The Explosive Child, HarperCollins, 2nd editions, NY, 2001 Greenhill L, et al. Efficacy and safety of immediate-release methylphenidate treatment for preschoolers with ADHD. J Am Acad Child Adolesc Psychiatry. 2006 Nov;45(11):1284-93. Howard BJ, 2005, Aggression/Opposition, In Child Health and Development interactive System, www.CHADIS.com Howard, B. J., Discipline in Early Childhood, Ped. Cl. N. Am. 38:1351, 1991. Howard BJ Advising Parents on Discipline: What Works 14 10/30/2012 Landy S, Peters RD, 1990, Identifying and treating aggressive preschoolers, Inf Young Child 3:24-38 Patterson GR: Living with Children, New Methods for Parents and Teachers, Research Press, 2612 North Mattis Ave., Champaign Ill 61820, 1976 Patterson GR, Forgatch M: Family living series Part 1 (5 cassette tt ttapes to t be b used d with ith Li Living i with ith Children), Champaign Ill: Research Press Co., 1975 Patterson GR, Forgatch M: Family living series Part 2 (3 cassette tapes to be used with Living with Children), Champaign Ill: Research Press Co., 1976 Peter RD, McMahon RJ, Quinsey VL,(Eds), 1992, Aggression and Violence Through the Life Span, Sage Publications, Newbury Park, CA Posner K, et. Al. Clinical presentation of attentiondeficit/hyperactivity disorder in preschool children: the Preschoolers with Attention-Deficit/Hyperactivity Disorder Treatment Study (PATS). J. Child Adolesc Psychopharmacol. 2007 Oct;17(5):547-62. S l Solomons HC HC, El Elardo d R R, 1991 1991, Biti Biting iin d day care centers: t Incidence, prevention and intervention. J Ped Health 5:191-6 Webster-Stratton, C, Kolpacoff M, Hollinsworth T, The long-term effectiveness and clinical significance of three cost-effective training programs for families with conduct problem children. J Consulting and Clin Psychol. 1989;57:550-53 15