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Epicardio Simulation™ St. Jude Medical™ MultiPoint™ Pacing User Guide 1. Access You may access the demo on your web browser here: www.epicardio.com/ep/sjm Or download the app here: www.epicardio.com/html/EpicardioDownload.html If you require technical assistance please contact: [email protected] 2. Introductory Steps 1. The Epicardio login window Type your login and password provided to you by the Brussels Coordination Center 2. The Epicardio EULA Scroll down to the bottom of the text and tap on: “I ACCEPT” 3. The St. Jude Medical™ Disclaimer - Tap on the light grey line at the bottom of the grey window to access this User Guide - Tap anywhere on the dark grey window to proceed © Epicardio Ltd 2016. Strictly Private and Confidential. Company Registered in England and Wales, UK, Registration No: 7585521 VAT No: 888190278 Company Address: 4th Floor, 18-20 Hill Rise, Richmond, Surrey TW10 6UA, UK Tel: +44(0)2089481080 Email: [email protected] Web: www.epicardio.com ! /!7 1 4. Patient with LBBB - Use your mouse or pad to control the camera view - Or tap on the preset camera views at the top left corner - Observe the wide QRS on Lead I ECG 5. Pacing from Distal 1 - RV coil - Tap on “PACE” in the MultiPoint™ Pacing window to start pacing from the Distal 1 electrode to RV coil - Observe that the QRS on Lead I ECG has narrowed, but only marginally 6. Phrenic Nerve - Tap on “Show Phrenic Nerve” to see the Phrenic Nerve and the Diaphragm - The Phrenic Nerve is stimulated due to its proximity to Distal 1 electrode, causing the Diaphragm to twitch - Tap on “Hide Phrenic Nerve” 7. MPP Vectors - Tap on “MPP Vectors” - Choose a different vector configuration e.g. Proximal 4 - RV coil + Mid 3 - RV coil - Observe the narrowing on the QRS in the Lead I ECG - Note: you may select and drag all pop-up windows © Epicardio Ltd 2016. Strictly Private and Confidential. Company Registered in England and Wales, UK, Registration No: 7585521 VAT No: 888190278 Company Address: 4th Floor, 18-20 Hill Rise, Richmond, Surrey TW10 6UA, UK Tel: +44(0)2089481080 Email: [email protected] Web: www.epicardio.com ! /!7 2 8. MPP Delays - Tap on “MPP Delays” - You may change the delay in ms between LV1 and LV2 (Delay 1) and between LV2 and RV (Delay 2) - Note: Small changes in the delay may not be visible due to the simulation time step 9. Pause and Scroll - Tap anywhere on the ECG line to pause the simulation - Scroll the blue time-line backwards by using the grey slider below the ECG line - You may also use the ←→ arrows on your keyboard to advance back and forth by one simulation step - Tap on the ECG line again to continue 10. Myocardial Contraction - Tap on the “Contraction” icon - Observe the synchronised myocardial contraction on the ventricles 11. MPP Measurements - Tap on “Measurements” to display: - S-L Delay: time delay between septum and lateral LV wall (points S and L) - LVEF: Ejection fraction % in the LV - Averaged dP/dt max - Note: LVEF is calculated only when contraction is switched on © Epicardio Ltd 2016. Strictly Private and Confidential. Company Registered in England and Wales, UK, Registration No: 7585521 VAT No: 888190278 Company Address: 4th Floor, 18-20 Hill Rise, Richmond, Surrey TW10 6UA, UK Tel: +44(0)2089481080 Email: [email protected] Web: www.epicardio.com ! /!7 3 2. Other GUI 12-Lead Patient ECG - Displays the 12-lead ECG of a relevant patient case - The pop-up window can be dragged around - Tap on the icon again to return to the main simulation window Controls on 12-Lead Patient ECG window: Changes Vector Configuration Closes 12-Lead Patient ECG window 12-Lead Simulated ECG - Displays live simulated 12-lead ECG - Tap on the icon again to return to the main simulation window Controls on 12-Lead Simulated ECG window: Closes 12-Lead Simulated ECG window © Epicardio Ltd 2016. Strictly Private and Confidential. Company Registered in England and Wales, UK, Registration No: 7585521 VAT No: 888190278 Company Address: 4th Floor, 18-20 Hill Rise, Richmond, Surrey TW10 6UA, UK Tel: +44(0)2089481080 Email: [email protected] Web: www.epicardio.com ! /!7 4 - Pauses the simulation - This has the same effect as tapping on the live ECG in the main simulation window - Displays the ECG graph paper - Enabled only when the simulation in paused 12x1 Displays the ECG in 12x1 or 6x2 format - Activates ECG calipers - Enabled only when the simulation is paused - Tap anywhere on the ECG to mark the “start” point of the caliper measure. Tap again - to mark the “end” point The caliper reports the distance in ms between the “start” and “end” blue lines. Displays the 12-Lead Simulated ECG in full window mode © Epicardio Ltd 2016. Strictly Private and Confidential. Company Registered in England and Wales, UK, Registration No: 7585521 VAT No: 888190278 Company Address: 4th Floor, 18-20 Hill Rise, Richmond, Surrey TW10 6UA, UK Tel: +44(0)2089481080 Email: [email protected] Web: www.epicardio.com ! /!7 5 Defibrillator - Activates the Defibrillator - Tap on “CHARGE” - When it flashes red/green, tap on “SHOCK” to defibrillate Heart View Options - Activated heart anatomy view options - Cross-section, coronary arteries and veins, main vessels and valves, torso, rib-cage, etc. Muscle Contraction - Activates myocardial contraction on ventricles - The muscle contracts in response to the electrical AP wave activation - The ventricles are displayed in cross-section and the atria in “ghost” mode - Note: the simulation may execute a little slower when the contraction is switched on Full Screen - Sets full screen mode - Tap on the icon again to exit full screen or press the ESC key on your keyboard © Epicardio Ltd 2016. Strictly Private and Confidential. Company Registered in England and Wales, UK, Registration No: 7585521 VAT No: 888190278 Company Address: 4th Floor, 18-20 Hill Rise, Richmond, Surrey TW10 6UA, UK Tel: +44(0)2089481080 Email: [email protected] Web: www.epicardio.com ! /!7 6 Preset Camera Views (top-left corner of application window) AP: Anterior Posterior view CRANIAL: Cranial view at +45º CAUDAL: Caudal view at -30º RAO: Right Anterior Oblique view at +60º LAO: Left Anterior Oblique view at -40º !: Intermediate views +/-: Zoom in/out Tools & Settings - Tap to toggle between pacing parameters and settings Heart Rate (bpm) Sets the heart rate in beats per minute Tap on the +/- buttons to increase/decrease the heart rate in 5 bpm steps Tap on the “Heart Rate” to reset the heart rate (default rate: 77 bpm) Range: 40-120 bpm - Pacing Rate (bpm) Sets the pacing rate of the pacing stimulus (in beats per minute) Tap on the +/- buttons to increase/decrease the pacing rate in 5 bpm steps Tap on the “Pacing Rate” to reset the heart rate (default rate: 55 bpm) Range: 40-120 bpm - Tutorials (top menu line) - Tap to access the Epicardio Simulation™ tutorials menu - To return back to the St. Jude Medical™ MPP tutorial go to: Tutorials -> SJM™ MultiPoint™ Pacing Help Opens a web browser window with links to the Epicardio User Guide, FAQ’s, etc. About - Displays the St. Jude Medical™ disclaimer - Tap anywhere on the grey window to return to the MPP tutorial © Epicardio Ltd 2016. Strictly Private and Confidential. Company Registered in England and Wales, UK, Registration No: 7585521 VAT No: 888190278 Company Address: 4th Floor, 18-20 Hill Rise, Richmond, Surrey TW10 6UA, UK Tel: +44(0)2089481080 Email: [email protected] Web: www.epicardio.com ! /!7 7