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Chapter 12 Water and Major Minerals Key Terms 1. ions: Atoms or groups of atoms with an electrical charge resulting from the loss or gain of one or more electrons. 2. calmodulin: A calcium-binding protein that regulates a variety of cellular activities, such as cell division and proliferation. 3. aldosterone: A hormone secreted from the adrenal glands that acts on the kidneys to regulate electrolyte and water balance. It raises blood pressure by promoting retention of sodium (and thus water) and excretion of potassium. 4. plasma: The fluid portion of the blood that contains blood cells and other components. 5. oxalate (oxalic acid): An organic acid in some leafy green vegetables, such as spinach, that binds to calcium to form calcium oxalate, an insoluble compound the body cannot absorb. 6. salts: Compounds that result when the hydrogen of an acid is replaced with a metal or a group that acts like a metal. 7. insensible water loss: The continual loss of body water by evaporation from the respiratory tract and diffusion through the skin. 8. electrolytes: Substances that separate into charged particles (ions) when dissolved in water or other solvents and thus become capable of conducting an electrical current. Often used interchangeably with the term ions. 9. fibrin: A stringy, insoluble protein that is the final product of the blood-clotting process. © 2014 Jones & Bartlett Learning, LLC, and Ascend Learning Company 10. osmosis: The movement of a solvent, such as water, through a semipermeable membrane from the dilute to the concentrated side until the concentrations on both sides of the membrane are equal. 11. phytate (phytic acid): A phosphorus-containing compound in the outer husks of cereal grains that binds with minerals and inhibits their absorption. Fill-in-the-Blank 1. Antidiuretic hormone (ADH) is a hormone secreted by the pituitary gland that increases blood pressure and prevents fluid excretion by the kidneys. 2. Anions are ions that carry a negative charge, while cations are ions that carry a positive charge. 3. Hydroxyapatite is a crystalline mineral compound of calcium and phosphorus that makes up bone. 4. Hypertension is a condition in which resting blood pressure persistently exceeds 140 mm Hg systolic or 90 mm Hg diastolic. 5. Trace minerals are present in the body and required in the diet in relatively small amounts compared with major minerals; they are also known as microminerals. 6. Wavelike motion of small hairlike projections on some cells is called ciliary action. 7. Osteoclasts are bone cells that break down bone structure and release calcium and phosphate into the blood. 8. Major minerals are required in the diet and present in the body in large amounts compared with trace minerals. © 2014 Jones & Bartlett Learning, LLC, and Ascend Learning Company Fill-in-the-Blank Summaries Water: The Essential Ingredient for Life Overall, water makes up 45 to 75 percent of your weight. The body maintains its electrolyte balance through the intake and excretion of water and the movement of ions. Positively charged ions are known as cations. Negatively charged ions are known as anions. About two-thirds (2/3) of body water is in the intracellular fluid, and one-third (1/3) is in extracellular fluid. The major components of extracellular fluid are interstitial fluid and blood plasma. To maintain the balance of sodium and potassium, all cell membranes incorporate sodium-potassium pumps that actively pump sodium out of the cell while allowing potassium back in. When electrolytes are more concentrated on one side of the membrane, then water flows to the side of higher concentration. Cells must contain the right amount of water. Too much and the cell will burst; too little and the cell will shrink. Too much water in the surrounding spaces causes edema. Short Answer 1. What is the most important role of the renin-angiotensin system? Perhaps the most important role of the renin-angiotensin system is its response to dietary sodium. It allows a person to consume either very small or very large amounts of sodium without causing major changes in extracellular fluid volume or blood pressure. 2. Describe how the kidneys adjust and manipulate urine excretion when water intake is too low. Describe the kidney’s production when the body has an excess of water. © 2014 Jones & Bartlett Learning, LLC, and Ascend Learning Company When water intake is low, the kidneys conserve water. While continuing to excrete solutes, they reabsorb water, thus decreasing urine volume and concentrating the urine. When the body has an excess of water, the kidneys form and excrete a large volume of dilute urine. 3. Although taste, availability, cultural patterns, and personal habits affect the amount of fluids we consume, thirst is our most important stimulus for drinking. There are four major stimuli for making us feel thirsty—what are they? 1) Increased osmolarity of the fluid surrounding the osmoreceptors in the hypothalamus 2) reduced blood volume and blood pressure 3) increased angiotensin II 4) dryness of the mouth and mucous membranes lining the esophagus 4. Chronic mild dehydration—a fluid deficit of as little as 1 to 2 percent of body weight— can cause declines in alertness and the ability to concentrate while increasing feelings of tiredness and headache. Identify two other consequences our body has as a result of chronic mild dehydration, and give an example of a daily skill this may affect. Chronic mild dehydration also impairs decision making and reaction times. This may be important for tasks that involve judgment and skill, such as driving a car. 5. Plant foods can be excellent sources of several minerals. Explain why the mineral content of plants can vary dramatically. The mineral content in plants varies depending on the mineral content in the soil in which it grows, as well as the maturity of a vegetable, fruit, or grain. 6. Identify the role(s) of sodium in the body. Sodium is the major cation in the extracellular fluid; it plays a critical role in regulating proper water distribution and blood pressure. © 2014 Jones & Bartlett Learning, LLC, and Ascend Learning Company 7. Identify the role(s) of potassium in the body. Potassium is the major cation in the intracellular fluid. With sodium, it regulates muscle contractions and nerve impulse transmissions. 8. Identify the role(s) of chloride in the body. Chloride is involved in many important metabolic functions. It is used to form the hydrochloric acid secreted in the stomach, and is important in the generation of nerve impulses as well as immune function. 9. Calcium is a major component of bones and teeth. What other body functions require calcium? In addition, calcium is required for muscle contraction, nerve impulse transmission, blood clotting, and regulation of cell metabolism. 10. Identify the role(s) of phosphorus in the body. Phosphorus is common in many crucial metabolic systems. It is used to activate and deactivate enzymes, and is an essential component of ATP, the energy source of the cell. 11. Identify the role(s) of magnesium in the body. Magnesium is a cofactor for more than 300 enzymes. Magnesium is required for cardiac and nerve function, and it helps form ATP. 12. Identify the role(s) of sulfur in the body. Sulfur is a component of the amino acids methionine and cysteine, as well as of the vitamins biotin and thiamin. Sulfur is important in drug detoxification and in maintaining acid–base balance. Labeling © 2014 Jones & Bartlett Learning, LLC, and Ascend Learning Company Trace the effects of water deficit by labeling each section of the image. (top to bottom) Hypothalamus; Osmoreceptors; Pituitary gland © 2014 Jones & Bartlett Learning, LLC, and Ascend Learning Company