Download i LIST OF ABBREVIATIONS Abbreviation Description

LIST
OF
ABBREVIATIONS
LIST
OF
ABBREVIATIONS
Abbreviation
Description
1. µl
Microlitre
2. µm
Micrometer
3. λMax
Absorbance Maxima (Wavelength)
4. µg/ml
Microgram/Milliliter
5. A.A
Acetic acid
6. ACN
Acetonitrile
7. AUC
Area under curve
8. BEH
Bridged ethylene hybrid
9. CDER
Center Of Drug Evaluation And Research
10. cGLP
Current Good Laboratory Practices
11. cGMP
Current Good Manufacturing Practices
12. cm
Centimeter
13. Conc.
Concentration
14. DOE
Design of experiment
15. EC
European Commission
16. FDA
Food and drug administration
17. h
Hour
18. H2O2
Hydrogen peroxide
19. HCl
Hydrochloric acid
20. HETP
Height equivalent to theoretical plates.
21. HPLC
High performance liquid chromatography
22. HPTLC
High performance thin layer chromatography
23. I.V.
Intravenous
24. ICH
International conference of harmonization
25. IS
Internal standard
i
26. ISO
International Standards Organization
27. IU
International units
28. IUPAC
International union of pure and applied chemist
29. Kel
Elimination rate constant
30. Ki
Inhibition constant
31. Km
Michaelis menten constant
32. LC
Liquid chromatography
33. LC
Liquid chromatography
34. LLOQ
Lower limit of quantification
35. LC-MS/MS
Liquid chromatography tandem mass spectrometry
36. LOD
Limit of detection
37. LOQ
Limit of quantification
38. m/z
Mass to charge ratio
39. MeOH
Methanol
40. mg
Milligram
41. mg/ml
Milligram/ milliliter
42. MI
Metabolite intermediate
43. min
Minute
44. MM
Michaelis Menten
45. mm
Millimeter
46. M
Molarity
47. MRM
Multiple reaction monitoring
48. MRT
Mean residence time
49. MS
Mass spectroscopy
50. MW
Molecular weight
51. N
Normality
52. NaCl
Sodium chloride
53. NADPH
Nicotinamide adenine dinucleotide phosphate
54. NCEs
New chemical entities
ii
55. ng
Nanogram
56. nM
Nanomolar
57. nm
Nanometer
58. NMT
Not More Than
59. ODS
Octadecyl silane
60. PDA
Photo diode array
61. P-gp
P-glycoprotein
62. pH
Negative logarithm of hydrogen ion concentration
63. PM
Preventative maintenance
64. PAH
Polycyclic aromatic hydrocarbon
65. QCs
Quality control samples
66. R.S.D.
Relative standard deviation
67. r2
Correlation coefficient
68. RE
Relative error
69. Rep.
Replicate
70. RH
Relative humidity
71. RP
Reverse phase
72. RRT
Relative retention time
73. RT
Retention time
74. SD
Standard deviation
75. Sec
Second
76. SIAM
Stability indicating assay method
77. SNP
Single nucleotide polymorphism
78. SSS
System Suitability Samples
79. SST
System Suitability Testing
80. Std.
Standard
81. t1/2
Half life
82. TLC
Thin layer chromatography
83. tmax
Time of maximum concentration
iii
84. UGTs
Uridine diphosphoglucuronosyl transferases
85. UPLC
Ultra performance liquid chromatography
86. US
United State
87. USP
United State of Pharmacopoeia
88. UV
Ultra-Violet
89. v/v
Volume/Volume
90. Vd
Apparent volume of distribution
91. Vmax
Maximal velocity of the reaction
92. w/v
Weight by volume
93. W/w
Weight/Weight
94. WHI
Women’s Health Initiative
95. µg
Microgram
96. µM
Micromolar
iv