Download Anti-DCP1A (aa 225-275) polyclonal antibody

Anti-DCP1A (aa 225-275) polyclonal antibody
Cat.No: DPABH-23374
Lot. No. (See product label)
PRODUCT INFORMATION
Antigen Description
Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated
mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after
stimulation by TGFB1.
Immunogen
Synthetic peptide, corresponding to a region within amino acids 225-275 of Human Dcp1a
(NP_060873.4).
Isotype
IgG
Source/Host
Rabbit
Species Reactivity
Human
Purification
Immunogen affinity purified
Conjugate
Unconjugated
Applications
WB, IP
Format
Liquid
Size
100 μg
Buffer
Constituent: 99% Tris citrate/phosphate. Note: pH 7 to 8
Preservative
Preservative: 0.09% Sodium azide
Storage
Store at 4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Antigen Gene Information
Gene Name
DCP1A DCP1 decapping enzyme homolog A (S. cerevisiae) [ Homo sapiens ]
Official Symbol
Dcp1a
Synonyms
DCP1A; DCP1 decapping enzyme homolog A (S. cerevisiae); mRNA-decapping enzyme 1A;
HSA275986; SMAD4IP1; SMIF; decapping enzyme hDcp1a; transcription factor SMIF; putative protein
product of Nbla00360; Smad4-interacting transcriptional co-activator; Nbla00360; FLJ21691;
Entrez Gene ID
55802
mRNA Refseq
NM_018403
Protein Refseq
NP_060873
MIM
607010
UniProt ID
Q9NPI6
Chromosome Location 3p21.1
Creative Diagnostics. All rights reserved
45-1 Ramsey Road Shirley, NY 11967, USA
Tel: 1-631-624-4882 Fax: 1-631-938-8221
E-mail: [email protected]
www.creative-diagnostics.com
1
Pathway
Deadenylation-dependent mRNA decay; Decapping complex; Destabilization of mRNA by Butyrate
Response Factor 1 (BRF1); Destabilization of mRNA by Tristetraprolin (TTP); Gene Expression; RNA
degradation;
Function
hydrolase activity; identical protein binding; protein binding;
Creative Diagnostics. All rights reserved
45-1 Ramsey Road Shirley, NY 11967, USA
Tel: 1-631-624-4882 Fax: 1-631-938-8221
E-mail: [email protected]
www.creative-diagnostics.com
2