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Transcript
PREVENTION
MODELS OF
OBESITY AND
CARDIOVASCULAR
DISEASES
CONGRESS
INFORMATION
CONTENTS
„
. . . . . . . . . . . . . . . . . . . . . . . . . . 3
COMMITTEES & ORGANISATION . . . . . . . . . . . . . . . . . 4
PROGRAM AT A GLANCE. . . . . . . . . . . . . . . . . . . . . . 5
SCHEDULE / DAY 1. . . . . . . . . . . . . . . . . . . . . . . . 6-7
SCHEDULE / DAY 2. . . . . . . . . . . . . . . . . . . . . . . . 8-9
LOCATION. . . . . . . . . . . . . . . . . . . . . . . . . 10-11
FLOOR PLAN. . . . . . . . . . . . . . . . . . . . . . . . . . . 12
REGISTRATION & CREDITS. . . . . . . . . . . . . . . . . . . . 13
GUIDELINES SPEAKER / POSTER PRESENTER . . . . . . . . . . 14
SOCIAL NETWORKING. . . . . . . . . . . . . . . . . . . . . . 15
WELCOME TO VIENNA. . . . . . . . . . . . . . . . . . . 16-17
SPONSORS. . . . . . . . . . . . . . . . . . . . . . . . . 18-19
ORAL PRESENTATIONS / INVITED ABSTRACTS. . . . . . . 20-37
POSTER PRESENTATIONS / SUBMITTED ABSTRACTS . . . 38-60
NOTES. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61
AUTHOR INDEX . . . . . . . . . . . . . . . . . . . . . . . . . 62
KEYWORD INDEX . . . . . . . . . . . . . . . . . . . . . . . . 63
INTRODUCTION
OBESITY AND CARDIOVASCULAR DISEASES
ARE THE MAIN CAUSES OF PREMATURE
DEATH IN WESTERN COUNTRIES.
WWW.POC-VIENNA-2016.EU
The WHO declared obesity – especially in
children and adolescents – as the most
challenging health problem of the 21th
century. Recent data from more than 19
million participants indicate that if the
post 2000 trends continue – by 2025 global
obesity prevalence will reach 17% in men
and 21% in women. As an answer, the WHO
and the EU claimed to implement effective
measures to halt the rise of the epidemy of
obesity and consequent diseases.
Several projects in various countries are
the one way, however there is no program
which could be an example for large-scale
successful programs in order to counter act
the global obesity challenge.
Concomitant with obesity, cardiovascular
diseases are the main cause for early
disabilities and death better understood
and can be much more easier prevented
– mostly through drug therapy.
We will bring experts in that field together
and really hope that new models and
regimes for early and sucessful prevention
models will be presented and discussed.
Vienna presents itself as a modern city with
high tradition and offers many attractions
from arts, music and science. The congress
team will be happy to welcome you in
Vienna and will support you in any aspect
to make your visit unique.
Univ.-Prof. Dr. Kurt Widhalm
LEGAL NOTICE
Publisher: Vienna Medical Academy, Alser Strasse 4, 1090 Vienna, Austria. Layout: strg.design – Bernhard Stranz. Photos: Fotolia.
All informations have been compiled carefully. Nevertheless, no guarantee can be given for the correctness.
2
3
COMMITTEES & ORGANISATION
PROGRAM AT A GLANCE
FRIDAY, 11TH NOVEMBER, 9:00 H
CONGRESS COMMITTEE
CO-ORGANISER
ORGANISING OFFICE,
B. Ludvik, Vienna
Österreichischer Herzfonds
SPONSORING & EXHIBITION
J. Simon, Vienna
EAROC
MANAGEMENT
 09:00-10:30 h
SESSION 1
S. Ring-Dimitriou, Salzburg
Beta-Judo Project
Vienna Medical Academy
 10:30-11:00 h
THE ROLE OF HEALTH POLICIES IN
O. Pachinger, Innsbruck
PMU Salzburg
Mrs. Susanne Pacher
G. Hanauer, Vienna
DAG – Deutsche Adipositas
Alser Strasse 4, 1090 Vienna
Gesellschaft / German Obesity
Tel.: +43 1 405 13 83-25
 11:00-12:00 h
SESSION 2
SCIENTIFIC COMMITTEE
Society
Fax: +43 1 405 13 83 925
 12:00-13:00 h
G. Kostner, Graz
Österreichische Ärztekammer
[email protected]
HOW TO BROADEN OUR KNOWLEDGE ON
OBESITY IN THE PUBLIC HEALTH SETTING?
H. Dieplinger, Innsbruck
FHchol Austria
COMBATING THE OBESITY EPIDEMIC
ABSTRACT MANAGEMENT
 13:00-14:20 h
SESSION 3
D. Weghuber, Salzburg
SECRETARY GENERAL
POC Vienna 2016 c/o
 14:20-14:50 h
A. Pietrobelli, Verona
Christina Pöppelmeyer, MSc
Vienna Medical Academy
THE THEORY BEHIND SUCCESSFUL
PREVENTION OF OBESITY
H. Hauner, Munich
Oliver Helk, MD
Mr. Manfred Vodrazka
S. Bühler, Leipzig
Alser Strasse 4, 1090 Vienna
C. Stefanutti, Rome
I. Lissau, Copenhagen
SECRETARY
Tel.: +43 1 405 13 83-13
Nina Nagy, MSc
Fax: +43 1 407 82 74
Karin Gatternig, MSc
[email protected]
 14:50-17:45 h
SESSION 4
EXAMPLES OF SUCCESSFUL
PROJECTS IN EUROPE
 19:30 h
SOCIAL NETWORKING
HEURIGEN EVENING
SATURDAY, 12TH NOVEMBER, 9:00 H
 09:00-10:45 h
SESSION 5
 10:45-11:00 h
NATIONAL ACTIVITIES: REPORTS
FROM VARIOUS COUNTRIES
 12:30-13:15 h
 13:15-14:15 h
SESSION 6
 14:15-14:40 h
LOOKING BEYOND OBESITY:
CVD PREVENTION IN HIGH RISK PATIENTS
 14:40-16:30 h
SESSION 7
HEREDITARY LIPID- AND
LIPOPROTEIN DISORDERS
4
5
SCHEDULE / DAY 1
FRIDAY, 11TH NOVEMBER, 9:00 H
INTRODUCTION / OPENING REMARKS
K. WIDHALM
09:00-09:10
SESSION 4
SESSION 1
SESSION 2
THE ROLE OF HEALTH POLICIES IN
COMBATING THE OBESITY EPIDEMIC
CHAIR: K. WIDHALM / J.M. BORYS
HOW TO BROADEN OUR KNOWLEDGE ON
OBESITY IN THE PUBLIC HEALTH SETTING?
CHAIR: S. BLÜHER / J. SIMON
EXAMPLES OF SUCCESSFUL
PROJECTS IN EUROPE
CHAIR: L. MORENO / S. RING-DIMITRIOU
Statement of the Austrian Government
Obesity in Europe - epidemiology and inequality
EPODE Method – From History to Best Practice (FR)
1.1. S. Karmasin, Austrian Federal Ministry
2.1. T. Lobstein, London
4.1. J.M. Borys
of Families and Youth, Vienna
11:00 - 11:20
FURGASSL-HUBER
WEINGUT & BUSCHENSCHANK
 Neustift am Walde 68, 1190 Vienna
19:30
14:50 - 15:10
09:10-9:20
Health Enhancing Physical Activity in Pre-school
VIASANO, experiences from a long lasting community
The position of the Austrian Social Security Institutions
and School-aged Children in Europe
based obesity prevention model (BE)
1.2. U. Rabmer-Koller, Vienna
2.2. H. Tschan, Vienna
09:20 - 9:30
11:20 - 11:40
The position of the Austrian Chamber of Physicians
Psychological aspects
1.3. K. Forstner, Salzburg
2.3. P. Warschburger, Potsdam 11:40 - 12:00
 Lunch Break
12:00 - 13:00
09:30 - 9:40
4.2. M. Roillet
15:10 - 15:30
Promoting Physical Activity in Italy to prevent Obesity
– The EUROBIS Program (IT)
4.3. P. Defeo
A food systems approach to obesity prevention
1.4. N. Pushkarev, EPHA, Brussels
NETWORKING EVENT
HEURIGEN EVENING
9:40 - 09:50
15:30 - 15:50
SALTO A Setting Approach – Kindergarten as Core
Unit of Community Based Intervention (AT)
Video statement
SESSION 3
4.4. S. Ring-Dimitriou
1.5. V. Andriukaitis, Commissioner for
Lessons learned from EPODE (WUV, EIN, NL)
health and food safety, Brussels
09:50 - 10:00
THE THEORY BEHIND SUCCESSFUL
PREVENTION OF OBESITY
CHAIR: T. LOBSTEIN / I. LISSAU
Open question-round
10:00 - 10:30
Principles of prevention of obesity: what works?
 Coffee break
10:30 - 11:00
3.1. S. Blüher, Leipzig 4.5. T. Visscher
13:00 - 13:20
15:50 - 16:10
16:10 - 16:30
Healthy nutrition as a challenge (AT)
4.6. J. Benedics
16:30 - 16:45
Economic aspects of prevention
3.2. J. Simon, Vienna
13:20 - 13:40
Strategic Use of Technology in Obesity Prevention
4.7. PANEL DISSUSSIONS
CHAIR: D. WEGHUBER / H. TSCHAN
PARTICIPANTS: M. SCHÄTZER (SALZBURG),
H. HERZOG (VIENNA)
3.3. M. Jones Bell / K. Waldherr, Stanford 13:40 - 14:00
What future steps need to be taken
Nutrition and Lifestyle Regimen for Infants
3.4. D. Weghuber, Salzburg
14:00 - 14:20
 Coffee Break (Poster Viewing)
14:20 - 14:50
to achieve our goals in prevention?
16:45 - 17:45
The organisers cannot assume any liability for changes in the program due to external or unforeseen circumstances.
6
7
SCHEDULE / DAY 2
SATURDAY, 12TH NOVEMBER, 9:00 H
SESSION 5
SESSION 6
SESSION 7
NATIONAL ACTIVITIES: REPORTS
FROM VARIOUS COUNTRIES
CHAIR: P. WARSCHBURGER / C.E. FLODMARK
LOOKING BEYOND OBESITY:
CVD PREVENTION IN HIGH RISK PATIENTS
CHAIR: H. DIEPLINGER / H. HAUNER
HEREDITARY LIPID- AND
LIPOPROTEIN DISORDERS
CHAIR: C. STEFANUTTI / T. STULNIG
National Activity: Report from Italy
Epidemiological data of cardiovascular diseases
New aspects of familial hypercholesterolemia (FH)
5.1. A. Pietrobelli / L. Pecoraro, Verona, Italy 09:00 - 09:15
6.1. H. Dieplinger, Innsbruck
in the youth
National Activity: Report from Greece
Prevention of cardiovascular diseases
13:15 - 13:35
7.1. K. Widhalm, Vienna
5.2. G. Chrousos, Athens, Greece
09:15 - 09:30
6.2. O. Pachinger, Innsbruck
13:35 - 13:55
14:40 - 15:00
The role of Nutrition in the treatment of familial
hypercholesterolemia
7.2. H. Hauner, Munich
Obesity in Denmark and actions to prevent obesity
The PEP Family Heart Study
5.3. I. Lissau, Copenhagen, Denmark
6.3. P. Schwandt, Munich
13:55 - 14:15
 Coffee break
14:15 - 14:40
09:30 - 09:45
15:00 - 15:20
Lipid lowering drugs and Lipoprotein Apheresis
National Activities: Report from Spain
5.4. L. Moreno, Zaragoza, Spain
7.3. C. Stefanutti, Rome
15:20 - 15:40
09:45 - 10:00
New Drugs: Mechanisms of actions
The role of lifestyle Intervention for treating
7.4. G. Kostner, Graz
15:40 - 16:00
obesity in children and adolescents
5.5. L. Grillich, Krems, Austria
10:00 - 10:15
Patient Organizations and the Medical & Science
Community: A Perfect Team
EDDY: a Viennese approach to school-based
7.5a. G. Hanauer-Mader, Vienna
16:00 - 16:20
prevention of obesity
5.6. O. Helk, Vienna, Austria
10:15 - 10:30
Making the difference: The important role of FH
patient organizations
7.5b. J. Payne, Maidenhead
National Activity: Report from Sweden
5.7. C. E. Flodmark, Malmö, Sweden
10:30 - 10:45
 Coffee break
10:45 - 11:00
16:00 - 16:20
Closing remarks
7.6. T. Stulnig, Vienna
16:20 - 16:30
PANEL DISSUSSION
CHAIR: P. SCHWANDT / O. PACHINGER
What is the ideal age for prevention programs? How
to include parents, what should not be done?
8
11:00 - 11:45
GUIDED POSTER SESSION
CHAIR: D. EHRINGER-SCHETITSKA
11:45 - 12:30
 Lunch Break
12:30 - 13:15
The organisers cannot assume any liability for changes in the program due to external or unforeseen circumstances.
9
LOCATION
0
500 M
Das Billrothhaus der Gesellschaft der Ärzte in Wien –
College of Physicians in Vienna
43 • 44
The Billrothhaus is the headquarter of the Gesellschaft der Ärzte in
Wien (College of Physicians in Vienna). It was named after Theodor
Billroth, an Austrian physician and former president of the society,
Theodor Billroth.
44
www.billrothhaus.at
5
5
 Frankgasse 8, 1090 Vienna, Austria
2
2
Underground: U2 station „Rathaus“ or „Schottentor“
2
2
Tram: Line 43/44 (Universitätsstraße)
2•5
Car Parking: Otto Wagnerplatz Tiefgarage,
Otto-Wagner-Platz, 1090 Vienna
0
POC
[ Lecture room ]
500 M
2 0 1 6
2
46
5
P
43 • 44
44
46
43 • 44
46
5
5
5
2
10
2
2
2
5
11
FLOOR PLAN
REGISTRATION
Poster,
Press
conference
What is covered by the registration fee?
Registration Desk opening hours
• Admission to all scientific sessions,
exhibition and networking event1
• Program and congress bag
• Coffee during breaks and light lunch
Friday, 11th November 2016,
Wardrobe
08:30-18:00 h
Saturday, 12th November 2016,
08:30-15:00 h
Certificate of Attendance
Confirmation of attendance will be issued
at the registration desk.
Registration
Please note that advance registration is mandatory in order
to receive a ticket for the networking event. The tickets will
be handed out at the registration desk. Limited attendance
(first-come, first-served)! Tickets will be checked at the entrance. Please note that there will be strictly no access without the
ticket.
Payment
received
before
15.09.2016
(reduced rate)
Payment
received
from
16.09.2016
(regular rate)
Participants
€ 350
€ 400
Abstract submitters
€ 300
€ 300
Students
€0
€ 100
1
Break
out
room
Lecture room
Catering & Exhibition
PARTERRE
FIRST FLOOR
CREDITS
POC Vienna 2016 was granted 12 European
CME Credits (ECMEC) by the European Accreditation Council for Continuing Medical Education (EACCME), Institution of the UEMS. The
number of credits will figure on the respective
confirmation, which will be handed out at the
registration. The rules of the EACCME state
that participants are kindly asked to fill in the
feedback (evaluation) form included in the
conference bag. It has to be returned to the
registration desk.

12
Participation in the scientific sessions of the
“International Symposium: Prevention models
of obesity and cardiovascular diseases” is
recognized within the Postgraduate Education
Programme of the Austrian Medical Chamber
with 9 credits.
Free WIFI access will be available on site
User: bhwireless
Password: bill22bill333
13
GUIDELINES SPEAKER –
POSTER PRESENTER
Projection and Technical Setting
The lecture room will be equipped with a
data projector. All major kinds of Power Point
and PDF‘s are accepted. You are also welcomed
to use your own laptop or Mac.
Please bring your data on a USB-stick
It is essential that you deliver your presentation
at the technician‘s desk in the lecture room
preferably in the morning of the day your talk is
scheduled, but not later than during the coffee
break preceding your session.
Poster Format
The usable size of the poster board is 90 cm
width x 130 cm height (approx. 35,4 x 51,2
inches) and posters should be in upright format. Adhesive material will be made available.
SOCIAL NETWORKING
Poster schedule for display, mounting and
removal
Your poster will be on display throughout the
conference days. Your presence and availability
for discussions at the poster is requested on
Friday, 11th November from 14:20 h to 14:50 h
(Poster Viewing during the Coffee Break) and on
Saturday, 12th November from 11:45 h to 12:30 h
(Guided Poster Session).
• Posters will be on display from
Friday, 11th November (9:00 h)
to Saturday, 12th November (14:40 h).
• Poster mounting will be possible on
Friday, 11th November from 8:30 h to 9:00 h
• Removal will be possible on
Saturday, 12th November from 14:40 h to 17:00 h
strict! Access before and after this time is not
possible!
Please note that posters not removed until
then, will be taken down by the staff of the
conference centre and will not be stored or
sent to the authors after the meeting.
HEURIGEN EVENING
FRIDAY, 11TH NOVEMBER, 19:30 H
Furgassl-Huber / Weingut & Buschenschank
Neustift am Walde 68, 1190 Vienna
Tel. +43 (0)1 440 14 05
E-Mail: [email protected]
Bus: Line 35A

14
Should you have any questions, our congress
staff will be pleased to help you. Please contact
the registration desk.
Please note that advance registration is mandatory in order to receive a ticket for the networking event. The tickets will be handed
out at the registration desk. Limited attendance (first-come, first-served)! Tickets will be checked at the entrance. Please note that
there will be strictly no access without the ticket.
15
WELCOME TO VIENNA
The feeling of wellbeing enjoyed by locals and
tourists has been confirmed repeatedly by leading
international studies and city rankings. Vienna is a
dream city for anyone with an interest in history.
Narrow medieval alleyways and grand boulevards
lead to historic sights such as the Imperial Palace (Hofburg), Belvedere Palace, Burgtheater, the
Spanish Riding School, St. Stephen’s Cathedral, the
Opera House, Karlskirche, or Schönbrunn Palace.
In 2001, the city centre was designated a UNESCO
World Heritage Site.
 TOURIST INFO
Tourist-Info Vienna
Albertinaplatz/Maysedergasse,
1010 Vienna
Daily from 9.00 am - 7.00 pm
Tourist-Info Vienna Airport
in the arrival hall
Daily from 7.00 am - 10.00 pm
Tourist-Info Main Station
Vienna has been synonymous with music for
centuries, and was home to Mozart, Beethoven,
Schubert and Johann Strauss. The Vienna Philharmonic Orchestra is one of the world‘s top orchestras and the Vienna Boys’ Choir is triumphantly
successful wherever it tours. Vienna possesses a
lively and vast array of cultural attractions from
classical or experimental theatre, film or dance
festivals, opera or operetta, as well as exhibitions
and concerts. The Museum of Fine Arts is one of
the world‘s largest and most distinguished museums housing priceless works of art. Art accompanies you wherever you go in Vienna – even some
of its underground stations are listed properties
because of their elegant ornamental Jugendstil
(Art Nouveau) style designed by Otto Wagner.
at the InfoPoint of ÖBB
Daily from 9.00 am - 7.00 pm
Wien Hotels & Info
Tel. +43-1-24 555
Fax +43-1-24 555-666
Monday - Saturday, 9.00 am - 7.00 pm
E-Mail: [email protected]
Web: www.wien.info/en
„
Vienna has 1,7 million inhabitants and
is situated on the banks of the Danube.
Austria’s capital ranks on top of the
most attractive cities world wide.
16
17
SPONSORS
SHOWCOOKING
Side Event on Monday, 14th November 2016. This event takes place without spectators.
as per 28th October 2016
18
19
ORAL PRESENTATIONS –
INVITED ABSTRACTS
1.4. A FOOD SYSTEMS APPROACH TO OBESITY PREVENTION
N. Pushkarev
 [email protected]
European Public Health Alliance (EPHA), Brussels, Belgium
1.2. THE POSITION OF THE AUSTRIAN SOCIAL SECURITY INSTITUTIONS
U. Rabmer-Koller
 [email protected]
Federation of Austrian Social Security Institutions, Vienna, Austria
The unsettling truth is that 30 years since the start
as it allows to join-up with other strong pressures to
of the rise of obesity no country has demonstrably
achieve a transition in the food system, but also from
contained or reversed this epidemic. Obesity is now
a realisation that many of the pressing concerns are
identified as a main global risk, on par with terrorism.
interrelated. The new EAT-Lancet Commission on the
Prevention of obesity and cardiovascular diseases is,
factors for cardiovascular diseases and obesity: - Last
The preventive approaches tried so far have not deli-
food system for instance recognises that “Expanding
due to prevalence and incidence of these widespread
summer we initiated a national exercise programme
vered at a sufficiently large scale. This can in part be
waistlines are a problem not just for dietitians and
diseases, a major field of action for the social insuran-
in public space in cooperation with the ministry of
attributed to a ‘cycle of inertia’ in public policy-making
population health specialists but, increasingly, for
ce institutions in Austria. As a strategic framework we
sport and the major sport federations in Austria. More
and strong pressure from interest groups not to de-
Earth system scientists too.”
formulated 10 health targets together with the major
than 120 weekly movement classes have being offe-
part substantially form the status quo. All this despite
stakeholders in Austria. As health of the population is
red to the general public at no charge. - The sickness
a string of sensible public health recommendations to
Topics explored during the session: Why agricultural
determined by living conditions and lifestyles, which
funds offer nutirition councelling to the Austrian peo-
experiment with policies for creating healthy food and
policy needs to be part of the obesity prevention di-
are influenced by many sectors and not by the health
ple. - A health promotion programme for pregnant
drink environments. The hypothesis pursued by EPHA
scussion.
sector alone, Austria decided that these health targets
and breastfeeding women and children up to 3 years
is that framing obesity and other diet-related disea-
should be based on a “health in all policies view”. They
of age (Healthy eating from the start!). - Smoking ad-
ses within a food systems context may be a promising
How unhealthy diets, climate change and antimicrobi-
provide a framework for coordinated action including
diction counselling is widely available in Austria. Most
strategy. A food systems approach relates all the food
al resistance have common roots.
a binding implementation plan, which is backed by all
oft the social security institutions provide smoking
system activities (growing, harvesting, processing,
Why public health needs to take account of the struc-
institutions, by all ministries involved. We also support
addiction counselling in an individual or group setting
packaging, transporting, marketing, consuming, and
ture of food supply chains.
the population at different points of life and settings
according to the quality standards of the social securi-
disposing of food and food-related items) to the out-
to prevent and target the common risk factors of obe-
ty. The Austrian smoking quitline, which celebrated its
comes of these activities for dietary health (incl. obe-
One of the conclusions is that a ‘food policy’ frame-
sity and cardiovascular diseases. Different strategies
10-year anniversary this year, with more than 3.500
sity and cardiovascular health), socio-economic issues
work is needed to properly conceptualise these inter-
reach from health promoting pre-birth interventions
Smoker counselling each month. - More than 1.300
and the environment (UNEP). This reframing may not
linked challenges and propose solutions that maximi-
within the family, health promoting schools and work-
companies received a seal of approval for its company
only be helpful for reasons of political expedience,
se co-benefits while minimising trade-offs.
places to the annual medical check ups. Just to men-
health promotion efforts.
tion a few of initiative concerning the common risk
20
21
2.1. OBESITY IN EUROPE - EPIDEMIOLOGY AND INEQUALITY
2.3. PSYCHOLOGICAL ASPECTS
T. Lobstein1,2
 [email protected]
1
World Obesity Federation, London, United Kingdom, 2Public Health Advocacy Institute of Western Australia, Perth, Australia
P. Warschburger
 [email protected]
University of Potsdam; Department of Psychology; Counselling Psychology, Potsdam, Germany
The presentation will consider recent trends in child
in obesity remain very significant between income
Obesity is not only a medical/nutritional problem
ty like increased anxiety or depression. In addition,
and adult obesity prevalence in Europe, and consider
groups in most EU member states. There is also evi-
but also a psychological one. In the literature two
a negative body-image, a lower self-esteem and
some of the causes of the variations in obesity pre-
dence of health differences between member states
main facets are considered: the role of psychological
disordered eating behaviors are common problems
valence, and highlighting some of the consequen-
ranked according to their degree of social inequality:
factors in the etiology of obesity and the psychological
among obese children and adolescents. Compared
ces. Recent trends show a continuing rise in obesity
countries with higher social inequality have higher
consequences of being obese. Although obesity is not
to normal-weight peers obese children and adole-
in the region for both children and adults, and the-
levels of ill health generally and a greater prevalen-
regarded as a mental disorder there is growing evi-
scents report a lower health-related quality of life.
re are significant consequences in terms of ill-health
ce of obesity in adults and in children. National and
dence that psychological issues play an important role
Especially children who internalize the weight-bias
in childhood as well as adulthood. In some member
regional policies to tackle obesity will need to include
in the multifactorial etiology of obesity. Psychological
are at increased risk for increased psychopathology
states there has been an easing of the rise in obesi-
universal as well as targeted interventions so that all
theories emphasize for instance the role of emotional
and impaired quality of life. Taken together psycho-
ty prevalence in childhood in recent years, and this is
the population can benefit, and especially those that
eating as coping strategy in response to stress, sad-
logical issues play a prominent role in obesity. In my
more clearly seen in children living in wealthier neigh-
need it most.
ness or just out of boredom. Recent studies illustrated
talk, I will mainly focus on the negative psychological
that an increased impulsivity or deficits in self-regula-
consequences of obesity for children and adolescents
tion strategies may play a role in the development of
and illustrate how these psychological issues may
obesity. On the other side there is consistent evidence
serve not only as consequences of obesity but also as a
that obesity is associated with increased mental
cause for the emergence and maintenance of obesity.
health risk as a sequelae. In our society being over-
Therefore, prevention and treatment approaches
weight or obese is viewed very negatively and obese
in that field should address these issues in order
persons are at a greater risk to experience weight-
to ensure a comprehensive care for children and
related teasing or being bullied by others. These
adolescents and their families and to break this
experiences may lead to psychological comorbidi-
vicious circle.
bourhoods and better-educated families. Inequalities
2.2. HEALTH ENHANCING PHYSICAL ACTIVITY IN PRE-SCHOOL
AND SCHOOL-AGED CHILDREN IN EUROPE
H. Tschan
 [email protected]
Dept. Training and Movement Science, University of Vienna; Centre of Sport Science and University Sports, Vienna, Austria
There is conclusive evidence that the physical fitness
preventing inactivity, overweight and obesity. The
and health status of children and youth are substan-
current presentation aims to give an overview about
tially enhanced by frequent moderate and vigorous
the level of physical activity and exercise among pre-
physical activity. Compared to sedentary young peo-
school and school-aged youth in Europe, based on
ple, physically active children and youth have higher
major studies measuring physical activity. Additio-
levels of cardiorespiratory fitness, muscular endu-
nally age- and sex specific characteristics, as well as
rance and muscular strength, and well-documented
effects of a low socio-economic status and migration
health benefits include reduced body fat, more
on health enhancing physical activity are highlighted.
favorable cardiovascular and metabolic disease risk
Furthermore, these review attempts to give an over-
profiles, and enhanced bone health. It is therefore
view about physical interventions performed and
a concern that only 1 in 5 children in the European
their outcomes on overweight and obesity, respecti-
Union reports taking part in regular (60 minutes
vely. Finally the different forms of sport participation
or more) moderate-to-vigorous intensity exercise.
(formal versus informal versus non-formal) and their
Combined with the rising prevalence of obesity the
different roles as health promotion strategies to
increasing level of sedentary behavior has resulted
increase physical activity in childhood are discussed.
in childhood being seen as an important period for
22
23
3.2. ECONOMIC ASPECTS OF PREVENTION
3.4. NUTRITION AND LIFESTYLE REGIMEN FOR INFANTS
J. Simon
 [email protected]
Centre for Public Health, Department of Health Economics, Medical University of Vienna, Vienna, Austria
D. Weghuber
 [email protected]
Department of Pediatrics, Paracelsus Medical University, Salzburg, Austria
The talk will use Geoffrey Rose’s prevention para-
the development of guidelines for statin usage in the
The prevalence of childhood overweight and obesity
life, when biological determinants of later obesity risk,
digm as theoretical framework and examine it from
UK based on evolving cost-effectiveness evidence
has risen substantially worldwide in less than one ge-
feeding behaviour and dietary preferences are
the viewpoint of health economics. The value of the
from the Heart Protection Study. Furthermore, latest
neration, a trend that is already seen in early child-
shaped. Some lifestyle and nutrition interventions in
“high-risk” strategy of prevention will be compared to
evidence on the costs and benefits of primary and
hood. It has been shown that rapid weight gain during
infancy have been shown to reduce subsequent obe-
those of the “population strategy” option supported
secondary prevention options for obesity will be
infancy is associated with an increased risk of obesity
sity risk. From the infant perspective, breastfeeding
with relevant examples. Examples to scrutinize the
presented together with the relevant economic
and weight gain during the first 24 months of life is
decreases the odds of childhood overweight. The use
presented theoretical framework will be sought from
evaluation methods and their limitations.
the best overall predictor of later obesity. The broad
of lower-protein formulas and a reduction of dairy
range of factors impacting on obesity require a mul-
protein intake during complementary feeding has
tifaceted approach on both a societal and individual
been suggested to be of protective value, although
level to halt the rise of the obesity epidemic. The Euro-
data are limited. There seems to be no protective
pean Action Plan on Childhood Obesity has identified
effect of later introduction of solid foods while early
eight key areas that warrant particular attention, one
introduction (before 17 weeks of age), shorter breast-
of which is the need to support a healthy start into
feeding duration, higher energy intake, shorter sleep
life. Progress has been made in the identification of
duration, high maternal control over feeding, are
causative factors and preventive measures in early
associated with the risk of childhood obesity.
the field of cardiovascular disease prevention using
3.3. STRATEGIC USE OF TECHNOLOGY IN OBESITY PREVENTION
M. Jones Bell1,2,3
 [email protected]
1
Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, United States, 2Lantern, San Francisco, CA, United States,
3
ICare, Medical University of Vienna, Vienna, Austria
The essence of prevention is to cease a health prob-
implementation and maintenance of obesity preven-
lem before it begins, or at the least, to stop disease
tion interventions. This talk describes how to stra-
progression. The very nature of this involves reaching
tegically employ technology through the lens of the
and engaging individuals who may not yet be expe-
RE-AIM framework in order to support the develop-
riencing negative consequences of a health problem.
ment, evaluation and implementation of health pro-
This is a well-known challenge in obesity prevention
motion and prevention programs under real-world
in which evidence-based strategies require lifestyle
conditions. A program of research developing and
changes by individuals, and often their families, who
evaluating StayingFit, an online obesity prevention
may not perceive a need for such changes. Preventive
intervention, conducted across several countries for
interventions require clever strategies to enhance
the last decade will be used as a case example. User-
motivation and/or modify behavior. Technology is not
centered design principles and industry best practices
a solution in and of itself but when used strategically
will also be provided to illustrate key points.
it can facilitate reach, efficacy/effectiveness, adoption,
24
25
4.2. VIASANO, EXPERIENCES FROM A LONG LASTING COMMUNITY BASED
OBESITY PREVENTION MODEL
4.4. SALTO: A SETTING APPROACH – KINDERGARTEN AS CORE UNIT OF COMMUNITY
BASED INTERVENTION
M. Roillet
 [email protected]
VIASANO ASBL/VZW, Brussels, Belgium
S. Ring-Dimitriou
 [email protected]
Department of Sport Science & Kinesiology, Paris Lodron-University of Salzburg, Austria; Obesity Academy Austria
Based on the EPODE methodology, VIASANO was
development of the programme. What is the best
In Austria 20% of boys and 18% of girls aged 4 to 6
macro-level the interpersonal level is the key layer for
launched in Belgium in 2007. Its objective is to prevent
status for CBPs? Initially exploited by Proteines Brus-
years are overweight and obese (WHO assessment;
SALTO actions, as kindergarten teachers and parents
childhood obesity by changing the environment of
sels, a health communication agency, VIASANO is now
Mayer et al., 2014). This is in line with European data,
(care givers) are identified as key drivers, because chil-
families and facilitating healthy choices related to
run by an NGO. What are the advantages of this new
where a range of overweight and obesity of 12% in
dren grow-up in the world of adults (Ring-Dimitriou et
food and physical activity. Communities and their
status? How to involve communities from 2 different
Rumania to 32% in Spain was reported (Caroli & Vania,
al., 2015).
stakeholders operate the change, involving repre-
cultures (the Flemish and the Walloon culture) and
2015). In our own SALTO sample (n=128 girls, n=135
Accordingly SALTO, Salzburg together against obe-
sentatives of the administration services and local
keep them motivated? How does VIASANO function
boys) 14% and 3% of girls as well as 13% and 6% of
sity, is an at least 3-years lasting initiative that focus
actors such as schools, general practitioners, sports
and how it has evolved over time? One of the pillars
boys where overweight and obese, respectively. This
on the competencies of care-givers to enable them to
clubs, leisure centres, shopkeepers and retailers, as-
of VIASANO is an ethical public-private partnership.
means nearly every 5th child in the kindergarten is
implement health enhancing actions in the daily life
sociations, etc. The VIASANO programme is currently
What are the strengths and weaknesses of such an
affected by an unhealthy body mass, i.e. one to two
of children. As a core setting in the community SALTO
managed by an NGO. It operates in collaboration with
economic model? And last but not least, what are the
children in a kindergarten group. Because overweight
encourages kindergarten teachers to get in contact
an independent expert committee, receives funding
challenges of evaluating such a programme? Mireil-
or obesity strongly tracks into adolescence and adul-
with other services like sport clubs or private capaci-
from private partners and is supported by Belgian
le Roillet, in charge of the daily management of the
thood early prevention strategies are warranted!
ties. SALTO relies on the EPODE method and is a mul-
political institutions as well as scientific associations.
programme from the very beginning will present the
The kindergarten seems to be a promising core set-
ti-method, multi-sectoral and multi-stakeholder pro-
Since the very beginning 10 years ago, VIASANO has
VIASANO story in detail and share learnings on the
ting, as the attendance is obligatory for five to six year
ject. Beside that, children, parents and kindergarten
gained a lot of experience in the management and
growth of the programme.
old children and a second obligatory year (4 to 5y) is
teachers will be investigated regarding physical activi-
already discussed at ministry level in Austria (Haas et
ty and eating preferences, physical fitness levels and
al, 2012). Beside this, policies with a special focus on
sociodemographic data. How we translate evidence
health promotion in early childhood are introduced
into practice and investigate practice-based evidence
over the last years (e.g. Kindergesundheitsstrategie,
in early childhood obesity prevention will be outlined
National Action Plans on Nutrition and Physical Ac-
in the presentation.
tivity). Beside a favorable political framework on the
26
27
4.5. LESSONS LEARNED FROM EPODE
T. L. S. Visscher1,2
 [email protected]
1
Windesheim University of Applied Sciences, Zwolle, Netherlands, 2Epode International Network, Paris, France
4.7. “DRINKING AND SNACK LICENSE” – NATIONWIDE INITIATIVE TO IMPROVE
THE NUTRITION-RELATED KNOWLEDGE AND DIETARY PATTERN
M. Schätzer
 [email protected]
SIPCAN - Initiative für ein gesundes Leben, Salzburg, Austria
Whereas the childhood obesity epidemic is main-
Dutch JOGG-approach a fifth pillar is added: linking
ly caused by environmental determinants making
prevention and management. The EPODE-approach
Background: School projects that aim at improving
as well as the nutritional knowledge was examined.
the unhealthy option too easy, it is clear that divers
has been shown to be effective and its impact is enor-
eating and drinking patterns among schoolchildren
348 schoolchildren from Viennese schools partici-
key-players in those environments have a role in de-
mous, meaning that many families and professionals
are effective in the fight against overweight and obe-
pated in this study. The nutrition-related knowledge
veloping healthy environments and thereby the pre-
have become part of the EPODE movement. Further,
sity. The scientific institute SIPCAN has developed
questionnaire (20 nutrition-related questions), was
vention of childhood obesity. The EPODE program is
the EPODE Promotion of Health Equity program has
nationwide initiatives in this field. An example of these
assessed before and after the intervention. Principal
an evidence-based and community-based approach
been shown to be effective in reducing socio-econo-
programs is the “Drinking and Snack License”. The
component analysis (PCA) was used to identify the
tackling childhood obesity. Key pillars of EPODE are
mic health disparities. This lecture in Vienna will ad-
main goal of this program is to emphasize the import-
dietary patterns of 24 food groups. It revealed two
political involvement, social marketing, public-priva-
dress the different aspects of evidence and impact
ance of a healthy diet and to motivate the students to
dietary patterns: energy-dense and healthful. BMI was
te partnership and monitoring and research. In the
from perspectives of the child, parents and professi-
inhabit a healthier nutritional behavior.
calculated based on self-reports.
Material & methods: The topics covered by the
Results: 4% of all schoolchildren were obese and 15%
“Drinking and Snack License” are in line with the
overweight. At baseline the distribution regarding
Austrian curriculum of 5th grade biology classes and
energy-dense and healthy eating patterns was ba-
the European curriculum for nutritional education
lanced between the intervention group (n=233; 49%
of children that are between 8 and 13 years old. The
vs 51%) and the control group (n=115; 55% vs. 45%).
project lasts for five weeks. Every week there is one
After adjusting for age, sex, and initial nutrition-rela-
unit addressing certain topics that the teacher will
ted knowledge, the intervention group showed a 1.8
work on with the students during one lesson. In addi-
times greater adherence to healthful dietary pattern
tion to the lessons the students observe their eating
[OR = 1.81 (95% CI 1.03, 3.2); p=0.039), compared to
and drinking habits with the help of a “snack journal”.
the control group. The intervention group showed a
During the program the parents receive weekly infor-
significant increase in nutrition-related knowledge
mation about the contents covered in class and are
[7.7 (7.3-8.0) vs. 9.3 (8.5-9.2) points; p<0.001].
onals in the families’ environments.
motivated to support their children. After completing
the 5th unit the students take part in a theoretical
Conclusion: This analysis showed that the “Drinking
and a practical exam and if they pass they receive a
and Snack License” can significantly improve the
“Drinking and Snack License”.
nutrition-related knowledge. After the intervention,
children had a greater adherence to healthful dietary
28
Evaluation: The effectiveness of the program has
pattern. Multiplication: In the school year 2016/17
been tested in a controlled intervention study in
more than 11.000 students from all regions of Austria
which the impact on the eating and drinking behavior
take part in the “Drinking and Snack License”
29
30
5.1. NATIONAL ACTIVITY: REPORT FROM ITALY
5.3. OBESITY IN DENMARK AND ACTIONS TO PREVENT OBESITY
A. Pietrobelli1,2, L. Pecoraro1
 [email protected]
1
Pediatric Unit, Verona University Medical School, Verona, Italy,
2
Pennington Biomedical Research Center, Baton Rouge, Los Angeles, CA, United States
I. Lissau1,2
 [email protected]
1
Clinical Research Centre, Copenhagen University Hospital, Hvidovre, Denmark,
2
Child Obesity Unit, Department of Child Health, University Hospital Skane, Malmö, Sweden
Italy is at the top level in term of pediatric obesity
ring conception period and pregnancy. furthermore,
Among children born in 2008, 9.3% were overweight
inspired by the Swedish Bunkeflo model. Two main
incidence/frequency. Recently the Italian Statistic Data
overweight/obese women who plan to be pregnant
and were 2.5% obese, whereas in for children born
differences remain between the Swedish and Danish
Center (ISTAT), reported that 24% of the subjects bet-
should reduce weight before conception. 2. Before and
in 2000, 14.1% were overweight and were 3.8 % obe-
school systems. In Sweden, children are served lunch
ween 6 to 17 years of age are overweight, with higher
during pregnancy, at birth and during early life, body
se at their latest measurement at school. Regional
every day, while Danish children bring lunch from
percentage in the South of Italy. The same report un-
composition measurements are crucial to monitor
differences occur with the lowest rates in the capital
home or buy at school if available. Additionally, Da-
derlined that one million of subjects between 6 to 11
growth. 3. The exclusive breastfeeding is recommen-
region and the highest rates in the neighboring regi-
nish children perform 45 minutes of physical activity
years of age are overweight or obese. It is well known
ded at the beginning of life until six months. 4. Four
on, namely the region of Zealand. These figures have
on a daily basis. Currently, some trials are taking place
that 30% to 60% of overweight or obese children will be
to six months of age is the optimal window to intro-
been relatively stable the past four years (Sundheds-
with the goal of preventing child obesity. However, a
overweight or obese in adult age. According with ISTAT
duce complementary feeding. Until one year of age,
datastyrelsen 2016). A review from 2006 initiated by
major issue is that most projects are concerned with
the excess weight has a result of 2,5 billion of euro
breast milk or follow-on formula must remain the main
the National Board of Health, shown that no Danish
treatment of obesity rather than preventing children
per year of cost. Several national projects are ongo-
source of feeding and cow’s milk must be avoided. 5.
studies used the school as an arena for preventing
from overweight and obesity in the first place. Rese-
ing: a. “Passi” study where information on prevalence
Fruit and vegetables liking begins early. Daily variety,
overweight and obesity among children (Lissau 2006).
arch on smoking has demonstrated that structural ch-
and frequency of obesity are presented together with
diversity in a meal and repeated exposure up to eight
However, starting August 2014, all children from the
anges have a strong effect on decreasing number of
suggestion on prevention; b. “Progetto Cuore” whe-
time are efficient strategies to increase acceptance
ages 6 to 15 (equivalent to grade 0 to 9) participate
daily smokers - it now remains to be seen if 45 minu-
re regular measurement of cardiac risk factors were
of food not well accepted at first. There is no need to
in 45 minutes of daily common physical activity in the
tes of mandatory daily physical activity at school will
collected together with treatment; c. Project HS-CSD
add sugar or salt or sugary fluids to the diet. 6. Res-
middle of the day. This initiative has obviously been
affect the national rates of overweight and obesity.
LPD reported prevalence and discussed possible pre-
pect the child appetite and avoid coercive “clean your
vention/treatment strategies; d. “Body Weight, Eating
plate” feeding practices. Adapt portion of food and
Patterns, and Physical Activity: the Role of Education”:
not to use food as reward for good behavior. 7. Limit
a long term project with analyses of life style and pe-
animal protein intake in early life to reduce the risk of
culiar suggestions on balanced diet and regular phy-
an early adiposity rebound. Growing-up milk should
sical activity among children and adolescents; e. “Gain
be preferred to cow’s milk in order to limit intake and
health: making healthy choices easier”, a national
meet essential fatty acids and iron needs. 8. The intake
project promoting fruit and vegetables together with
of adequate fat containing essential fatty acid should
Spain, as the other Mediterranean countries, has a
on “Nutrition, Physical Activity and Obesity” (NAOS)
regular physical activity; f. Health Behavior in School-
be promoted. 9. Parents have a model role in feeding,
high prevalence of overweight and obesity in child-
and equivalent strategies in all the Spanish regions.
aged Children (HBSC), in conjunction with World Health
with TV and other screens turned of during meals.
ren. The last survey, conducted in 2013, in a nationally
However, little economic investment has been alloca-
Organization, targeted adolescents, promoting infor-
10. Preventive interventions consisting in promoting
representative sample of 3.426 children aged 7-8 ye-
ted to such initiatives. The main contribution has been
mation on healthy diet and healthy life style. Another
physical activity and child has to get sleep sufficient-
ars, showed a prevalence of overweight of 23.2% and
the development of two surveys in the framework of
interesting project coming from the Mediterranean
ly. In fact, a short sleep duration may be associated
obesity of 10.5%, using the IOTF standards. This study
COSI (2011 and 2013) and more recently the National
Nutrition Group (MeNu Group) a working group of
with increased risk of developing obesity. The Italian
was performed within the COSI (Childhood Obesity
Nutrition Surveyof children and adolescents (ENALIA,
researchers from the Mediterranean region willing to
Minister of Health recently presented a “policy maker”
Surveillance Initiative) Initiative. These results, com-
Encuesta Nacional de Alimentación en la población in-
contribute through their research or medical activities
where is mandatory a commercial spot control, taxes
pared with previous surveys seem to show a slight
fantil y Adolescente) that will provide information of
to the prevention of pediatric obesity. This group ela-
on soft drinks, clear information on the labels, together
decrease in the observed prevalences. In terms of
dietary intake in children from 6 months until 17 ye-
borated a proposal of 10 good practices to help pre-
with support of promotion of healthy diet and regular
research, there are intervention studies that have
ars. In summary, there are some activities that should
vent obesity in the first 1,000 days. 1. Both mother and
physical activity. Given the suggestion described in this
been performed in the recent years, such as IDEFICS
contribute to tackle the childhood obesity epidemic in
father behavior matter. A balanced diet with adapted
presentation, concerted public health efforts are nee-
or ToyBox, both funded by the European Comission.
Spain.
excessive fat and protein intake and favoring fruits
ded to achieve the healthy objectives for obesity and
In terms of public health, there is a National Strategy
and vegetables is recommended for both parents du-
nutrition and to fight the childhood obesity epidemic.
5.3. NATIONAL ACTIVITIES: REPORT FROM SPAIN
L. A. Moreno
 [email protected]
GENUD Research Group, Universidad de Zaragoza, Zaragoza, Spain
31
5.5. THE ROLE OF LIFESTYLE INTERVENTION FOR TREATING OBESITY IN CHILDREN
AND ADOLESCENTS
L. Grillich
 [email protected]
Danube University Krems, Krems, Austria
5.6. EDDY: A VIENNESE APPROACH TO SCHOOL-BASED PREVENTION OF OBESITY
K. Widhalm, O. Helk, C. Poeppelmeyer, O. Pachinger
 [email protected]
Austrian Institue for Clinical Nutrition, Vienna, Austria
Introduction: The prevalence of obesity, poor lifestyle
Protocoling), sports- scientific (Acclerometry, testing
Research Objective: To investigate lifestyle inter-
baseline and follow-up assessments. At 10-12 months
and related cardiovascular- and metabolic diseases is
of physical capabilities), psychological (concentration
vention effects of a structured 10-12-month exerci-
significant favorable effects were observed in several
on the rise in industrialized countries worldwide. Due
tests, AD-EVA questionnaire) and medical (lipid- and
se and nutrition program for overweight and obese
outcome measures: For example a change in the
to the fact that conventional treatment of obesity and
vitamin profile, glucose, insulin), bioimpedance analy-
schoolchildren aged 6 to 18 years.
distribution of weight related groups (p<.00) (less
unhealthy habits is difficult and often fruitless, pre-
sis) assessments.
obese and morbid obese but more overweight
vention programs have gained importance in recent
Study Design: Prospective uncontrolled before and
children), less eating to cope with unpleasant emo-
years. We present the results of the EDDY-pilot trial,
Results and Discussion: Our standardized interventi-
after study with assessments at baseline and 10-12
tional states and situations (children p<.00), higher
in which we aimed to implement a standardized in-
on was successfully implemented in the participating
months. The targets of intervention were overweight
satisfaction with their figure (children p<.00) and
tervention in Viennese Schools and evaluate its practi-
intervention schools. The control group showed a ten-
and obese children between seven and 18 years who-
better motor skills (children p<.00). Parents reported
cability and efficiency. Methods: EDDY is cluster-ran-
dency to have higher body fatpercentages and mean
se BMI is above age and sex-specific cut-off points[1]
higher ability to adhere to health promoting recom-
domized, controlled pilot study. 4 schools in Vienna
LDL at follow up when compared to baseline. This ef-
and their parents. The intervention was implemented
mendations (p≤.01) and lower preferences for snacks
participated and were divided into intervention- and
fect occurred in the intervention group on a reduced
in cooperation with children and youth departments
(parents p=.01). Parents and children showed a lower
control group in a 2:2 ratio. A total of 146 adolescents
scale, possibly reflecting the success of the interventi-
of regional hospitals and consisted of 120 hours of
wish for weight reduction (p=.02; p≤.01). No relevant
aged 10 to 14 participated. A standardized interven-
on. In regard to the QUICK-index values insulin sensi-
exercise and nutrition training (60 hours for the chil-
changes could be observed in the eating and exercise
tion of a total of 25 lessons was implemented by ex-
tivity has decreased in both intervention- and control
dren and 60 hours for their parents) during 10-12
habits of children, or in most of their cardiovascular
perts. The topics discussed in these lessons involved
group. It is possible however that this is an effect of
months. Main outcome measures included eating and
risk factors.
nutrition, physical activity and physiology. The success
pubertal age. Further trials will be required to assess
of the intervention was evaluated by nutritional-scien-
the reproducibility of our findings in larger cohorts.
exercise habits, well-being, cardiovascular risk factors
(blood pressure, weight, body-mass index, serum li-
Conclusions and Implications for Practice:
pids, blood glucose), motor skills and preclinical and
The lifestyle Intervention program had a positive
clinical eating disorders. The statistical analysis was
effect on relevant outcome measures at children
done with t-test and Wilcoxon-Test (depending on
(distribution of weight related groups) and positive
the preconditions). The last-observation-carried-for-
effects on parents. But there was no effect in cardio-
ward method was used to minimize selection effects
vascular risk factors and exercise habits and only
caused by dropouts.
a limited effect on eating habits of children. Due to
tific (Food Frequency Questionnaires, Nutritional
5.7. NATIONAL ACTIVITIES: REPORT FROM SWEDEN
C. E. Flodmark
 [email protected]
Dept of Pediatrics, Skåne University Hospital in Malmö, Malmö, Sweden
the fact, that it was not possible to create a control
Population Studied:
group the positive effect in motor skills could also be
In Sweden preventive actions and health care is of
the different growth charts have been under debate
157 children aged 6 to 18 years and their parents.
attributable to aging. Therefore there is a recommen-
major focus in the state financed health care system.
as the national standard has difficulties in surviving
dation for a critical revision of the program especially
Besides research, child health care covers 98% of all
when there is an increasing influence from software
Principal Findings: At baseline the parents agreed
the theoretical foundation and implementation of the
children and school health care has a similar high co-
developers from companies as the state has no de-
to their children´s participation in the study. 117
measures to change eating and exercise habits.
verage. In these health care organizations there are
velopment in this area. Focus is also an e-health whe-
children (mean age 11.45; 56% female, 45.5%
[1] the 90 th. percentile for overweight and the 97
differences in how much resources is put into pre-
re different solutions are under development.
morbid obese, 38.6% obese; 14.5% overweight) and their
th. percentile for obesity (Wiegand, 2005)
vention of obesity. In research different behavioural
parents (mean age 41; 86% female) completed the
programs have been studied where motivational interviewing (MI) has been tested in several studies. The
different studies give conflicting results. Furthermore
32
33
6.1. EPIDEMIOLOGICAL DATA OF CARDIOVASCULAR DISEASES
6.3. THE PEP FAMILY HEART STUDY
H. Dieplinger
 [email protected]
Division of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria
P. Schwandt
 [email protected]
Arteriosklerose-Präventions-Institut, Munich-Nuremberg, Germany
Despite a significant decline within the last decades,
industrialised countries) between men and women
Background: The Framingham Heart Study was the
more frequent in Iranian and Brazilian while the pre-
cardiovascular disease (CVD) remains the leading cau-
and among different socio-economic subpopula-
first community-based study which demonstrated
valence of hypertension was lowest in Iranian youth4.
se of death among Europeans and around the world.
tions. This overview provides a current update on the
that the combination of traditional risk factors subs-
Weight-related normative blood pressure percentiles
An estimated third of all deaths worldwide were cau-
burden of CVD, and in particular coronary heart
tantially increased the risk of cardiovascular diseases
for youth might deserve more debate5. Because chil-
sed by CVD in 2010, more than all communicable,
disease (CHD) and stroke, across the countries of
(CVD) which was confirmed and extended by many in-
dren may have more frequent contacts with the he-
maternal, neonatal and nutritional disorders com-
Europe and worldwide and will discuss key data
terventional studies among adults and children.
alth care system than their young parents we tested
bined, and double the number of deaths caused by
in relation to mortality and morbidity from CVD. A
cancers. CVD prevalence and incidence data in Euro-
particular emphasis will be placed on the importance of
Purpose: Because family-based studies using lifestyle
detected by screening their children6. In fact, this pro-
pe and worldwide show that the burden of mortali-
conventional and novel diagnostic markers (both ge-
change are scarce we started the community-based
cedure was an efficient case-finding strategy among
ty continues to show large geographic inequalities
netic and environmentally driven) for early detection and
prospective Prevention Education Program (PEP) in
2720 child-parent pairs. In 852 biological families we
among different countries. Furthermore, significant
possible therapeutic intervention to fight CVD.
the school year 1993/94. The PEP Family Heart Study1
evaluated the association of nutrition, leisure time
is a 14 years’ follow-up study for assessment of CVD
physical activity and smoking with seven conventio-
risk factors and sustained lifestyle change among chil-
nal CVD risk factors which were also significantly as-
dren and parents.
sociated between parents and children7. Daily ener-
differences can also be obvserved (particularly in
whether silent CVD risk factors in parents could be
6.2. PREVENTION OF CARDIOVASCULAR DISEASES
O. Pachinger
 otmar.pachinger@tirol-kliniken
Medical University of Innsbruck, Innsbruck, Austria
higher in daughters (35.4%) and sons (26.7%) than in
of all elementary school districts in the city of Nurem-
fathers (15.7%) and mothers (10.6%) and hypertensi-
berg participated in this study. Yearly surveys were
on was 2.5 fold higher in mothers and 1.7 times higher
performed in terms of structured interviews including
in fathers. Youth exposed to second-hand smoke had
The relationship of obesity to cardiovascular mortality
cardiovascular disease prevention: prevention should
personal and family history, physical activity, smoking
a far more adverse risk profile. A 1 year’s follow-up un-
has been recognized for many years. It also has been
start early in life; adoption of a healthy life style is
and nutritional habits, anthropometric examination,
der real life conditions demonstrated that continuous
recognized that overweight is associated with a shor-
fundamental; focus on family and parenting; primary
fasting blood analyses, seven days weighted dietary
control and sustained counseling on healthy nutrition,
ter life span. Cardiovascular consequences of obesity
care is an important setting for population and high
protocols. Yearly personal health passports and nu-
recreational physical activity, and decreased tobacco
involve atherosclerosis, hypertension, left ventricular
risk approaches to prevention. The broad food and
tritional protocols were used continuously amending
smoke exposure is a realistic approach improving
hypertrophy as direct cardiac consequences; in additi-
activity environment must be understood for inter-
the individual yearly counseling on healthy lifestyle.
modifiable CVD risk factor profiles in healthy school
on metabolic co-morbidities such as insuline resistan-
ventions to be succesfull, education alone is unlikely
ce, type II diabetes mellitus, dyslipidemia, metabolic
to be effective. Therefore, focus on behaviour change
Results and conclusions: Among 3038 adolescents
syndrom are indirectly affecting the cardiovascular
techniques; prevention approaches to diet and physi-
abdominal adiposity in terms of elevated waist cir-
References: 1. Schwandt P, Geiss HC, Ritter MM,
system. In general, two approaches to prevention
cal activity should be taylored to the age and develop-
cumference (WC) and waist-to-height ratio (WHtR)
Üblacker C, Parhofer KG, Otto C, Laubach E, Donner
are recommended: 1. Population approach applies
mental stage of the child. In cardiovascular disease
was associated with a higher risk of hypertension (OR
MG, Haas GM, Richter WO. The Prevention Education
to everyone 2. High-risk approach: identification of
prevention doctors need to play a major role and this
2.5), hypertriglyceridemia (OR 4.9), elevated LDL-C (OR
Program (PEP). A prospective study of the efficacy of
those at high risk and more intensive intervention
needs to be improved!
2.0), low HDL-C (OR1.6) and fasting blood glucose (OR
family-oriented life style modification in the reduc-
1.3)2. Based on our percentiles and others we preclu-
tion of cardiovascular risk and disease: Design and
de the use of a universal cutoff of 0.5 for WHtR3. The
Baseline Data J Clin Epidemiol 1999; 52: 791-800. 2.
prevalence of abdominal adiposity was similar to Ira-
Schwandt P, Bertsch T, Haas GM. Anthropometric
nian and Brazilian youth whereas dyslipidemia was
screening for silent cardiovascular risk factors in ado-
for these individuals. There are several principals for
34
gy consumption above the recommended level was
Design: First graders and their families living in 94%
children and their parents8.
35
7.3. LIPID LOWERING DRUGS AND LIPOPROTEIN APHERESIS
lescents: The PEP Family Heart Study. Atherosclerosis
J Obesity 2015; 39; 1508 6. Schwandt P, Bischoff-Fer-
2010; 211: 667 - 671. 3. Schwandt P, Haas GM. Is the
rari HA, Staehelin HB, Haas GM. Cardiovascular risk
ratio waist circumference to height of 0.5 a univer-
screening in school children predicts risk in parents.
sal measure for abdominal adiposity in children and
Atherosclerosis 2009; 205: 626-631. 7. Schwandt P,
adolescents? International J Obesity 2016; 40:1141-
Haas GM, Liepold E. Lifestyle and cardiovascular risk
1142. 4. Schwandt P, Kelishadi R, Ribeiro RQC, Haas
factors in 2001 child parent pairs: the PEP Family
GM, Poursafa P. A three-country study on the compo-
Heart Study. Atherosclerosis 2010; 213:642-648. 8.
Children at high risk because of a family history of
zygous and statin refractory heterozygous FH (HoFH,
nents of the metabolic syndrome in youth: The BIG
Schwandt P, Bertsch T, Haas GM. Sustained lifestyle
premature CVD and/or hypercholesterolaemia should
HeFH). However, the extent of cholesterol-lowering
Study. Intern J Pediatric Obesity 2010; 5:334-341. 5.
advice and cardiovascular risk factors in 687 biologi-
be targeted. Other risk factors for Atherosclerotic
achieved is often insufficient to meet the targets set
Schwandt P, Haas GM. Why stigmatize overweight
cal child-parent pairs: The PEP Family Heart Study.
Cardiovascular Disease (ASCVD) such as hyperten-
by current guidelines. The recent advent of three new
young people as hypertensive by using normative
Atherosclerosis 2011; 219: 937-945.
sion, overweight and diabetes, should be also taken
classes of lipid-lowering agents provides new hope
into account. The measurement of other ASCVD risk
that the latter objective may now be achievable. The-
factors with prognostic value, such as the assessment
se drugs act either by reducing low density lipoprotein
of Lp(a), is currently strongly suggested. Pediatric lipo-
(LDL) production by inhibiting apolipoprotein B syn-
protein apheresis (LA) is an extracorporeal treatment
thesis with an antisense oligonucleotide (mipomer-
of children with genetically determined dyslipidaemi-
sen) or by inhibiting microsomal triglyceride transfer
as, namely Homozygous Familial Hypercholestero-
protein (lomitapide), or by enhancing LDL catabolism
laemia (HoFH), a pernicious disease characterized by
via monoclonal antibody-mediated inhibition of the
skin lesions, such as cutaneous xanthomas at birth or
activity of proprotein convertase subtilisin/kexin 9
percentiles from non-overweight youth? International
7.1. NEW ASPECTS OF FAMILIAL HYPERCHOLESTEROLEMIA (FH) IN THE YOUTH
K. Widhalm
 [email protected]
Austrian Academic Institute for Clinical Nutrition and Department of Pediatrics, Medical University of Vienna, Vienna, Austria
C. Stefanutti
 [email protected]
Extracorporeal Therapeutic Techniques Unit - Lipid Clinic and Atherosclerosis Prevention Centre - Immunohematology and Transfusion Medicine - Umberto I Hospital - Department of Molecular Medicine, ‘Sapienza’ University of Rome, Rome, Italy
The prevalence of FH is most probably 1:200 in the
age of 4.5 years before undergoing any treatment. All
by early childhood (eg, planar xanthomas, tuberous
(PCSK9) (evolocumab). Depending on the outcome of
European population. It is evident that only a very
other patients are in a good condition however seve-
xanthomas; later, tendon xanthomas), arcus corneae,
current trials, it seems likely that these agents, used
small minority of the affected young subjects is di-
ral of them developed aortic stenosis. In the hetero-
early atherosclerotic impairment of coronary arteries
alone or combined with LA, will markedly improve
agnosed and subsequently undergoing treatment.
zygous FH patients dietary therapy seems to be the
and aortic valve. HoFH children ASCVD risk is extre-
the management of refractory FH. Unfortunately, the
On the other hand it has been proved that athero-
first column of treatment. Thus, recent data show that
mely elevated. The natural history of these young and
above mentioned novel lipid-lowering drugs have no
sclerosic lesions in the subjects with FH can be seen
substitution of animal protein by soy protein is able to
very young patients, evolves towards exitus in the
indication in the treatment of children, albeit clinical
in the pediatric age group and these manifestations
lower LDL-C levels by approx. 10%; by this treatment
1st or 2nd decade of life, if appropriate and intensive
trials on the use of PCSK9 inhibitors in children are
can be reversed by adequate treatment. An excellent
in about 1/3 of young children, drug treatment can
treatment is not warranted. At present, LA, combined
on the way. At least for now, LA remains the mainstay
example of this phenomenon is the rare form of FH
be postponed. Obviously the introduction of drugs
with high-dose statin and ezetimibe therapy, is the
therapy for children at very high ASCVD risk.
in the homozygous form. 9 patients with hoFH have
is the appropriate way of treatment in children and
best available means of treating patients with homo-
been diagnosed and consequently treated (mostly
adolescents with FH. There are strong arguments to
with LDL-apheresis and drugs) in the Vienna group
force the introduction of new drugs like the PCSK-9
within the last 35 years. The oldest patient survived
inhibitors even in childhood in order to improve the
until the age of 36 years. He suddenly died on an acu-
outcome and the inhibition of atherosclerotic lesions
te myocardial infarction. The youngest patient (with a
in young patients.
very aggressive LDL-receptor gen mutation) died at an
36
37
7.4. NEW DRUGS: MECHANISM OF ACTION
7.5.B. MAKING THE DIFFERENCE: THE IMPORTANT ROLE OF FH PATIENT ORGANIZATIONS
G. M. Kostner
 [email protected]
Institute of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria
J. Payne
 [email protected]
HEART UK - The Cholesterol Charity, Maidenhead, Berkshire, United Kingdom
Plasma lipids involved in atherogenesis are choles-
or by increasing their catabolism. To the first category
Jules Payne is Chief Executive of HEART UK - The Cho-
applied. Jules is also Chair of FH Europe - A Europe-
terol and triglycerides (TG). Whereas the role of TG as
belongs Niacin, MTP inhibitors and the new RNA inter-
lesterol Charity, a patient and professional organisati-
an FH patient network of 24 countries. The network
risk factor for CVD is still under debate, there is no
ference dugs like mipomersen or ISIS-APO(a)Rx from
on providing expert support, guidance and education
was set up in March 2015 and they share a vision to
doubt that the culprit is cholesterol. Cholesterol is
IONIS. The most promising new drug, however are
to patients, their families and health care professio-
identify all the FH cases in Europe. These organisa-
transported in HDL as the “god cholesterol” and in LDL
the PCSK9 inhibitors that may be administered addi-
nals treating those patients with high cholesterol and
tions come together to share best practice and sup-
and Lp(a) as the bad. The strategy to combat CVD is to
tionally to statins. At the appropriate dosage PCSK9
other lipid conditions. She will cover some of the
port each other whilst raising awareness of FH. It’s
raise HDL and to lower LDL and Lp(a). Niacin has been
inhibitors effectively lower LDL to the target values
most recent activities which HEART UK are doing to
better together! Jules will share the planned activities
propagated for HDL-raising but it is not sold anymore
proposed in most guidelines. The mode of action of
raise awareness of the dangers of high cholesterol, in
that have raised awareness around Europe and the
in most countries. The lowering of LDL and Lp(a) may
all these drugs will be discussed.
particular FH. She will discuss their Ambassador pro-
world and future plans around lobbying European
gramme and their newly planned Children and Young
Parliament, providing support for each country to ef-
People’s Programme. As well as these activities she
fectively lobby the Government in their own country,
will also cover how HEART UK managed to overturn
attending health care professional conferences and
the decision of NICE to recommend a new category
holding network meetings and more. This talk will de-
of drug and also how their activities keep the matter
monstrate the importance of patient involvement and
high on the political agenda in the UK, which is star-
the power they can have.
be achieved by reducing the rate of their biosynthesis,
7.5.A. PATIENT ORGANIZATIONS AND THE MEDICAL & SCIENCE COMMUNITY:
A PERFECT TEAM
G. Hanauer-Mader
 [email protected]
FHchol Austria, Vienna, Austria
38
ting to get traction, but pressure will continue to be
From personal suffering to the collective mission:
tific data and findings a face and are thus an important
Starting from my personal story of familial hypercho-
voice for science & medicine.Empowered patients can
lesterolemia and my daughter‘s being severly affec-
educate other patients, they know about their risks and
ted by this condition, I will speak about my personal
have a better compliance. Also, they can raise public
motivation to form the first FH advocacy group in the
awareness through emotions and thus put pressure on
German-speaking countries in 2004 which eventually
public health authorities. Awareness raising, lobbying,
turned into the FHchol Austria Patient Organization in
media relations: In the course of my lecture I will also
2011 and into a collective mission. Patients, clinicians &
give a few examples of how the FHchol Austria patient
scientists - a powerful team: I will then lecture on a po-
organization is addressing a broader public and politi-
werful liaison: the joining forces of patients, clinicians
cians (for instance through our press conferences and
& scientists.While scientists are the experts in basic re-
media relations efforts, FH Awareness Days supported
search and drug development, clinicians are experts in
by local politicians, workshops, lectures, conferences,
the direct communication with and treatment of pati-
etc.)Our political pressure targets primary prevention
ents.Patients, on the other hand, show that prevention
through early screening & treatment, reimbursement
of CVD is possible despite their chronic condition. They
of innovative medication or the establishment of an
are role models for other patients and they are the
Austrian-wide FH registry. International cooperation -
faces of FH. Empowered patients: Empowerd patients
FH Europe: Last but not least I will talk about internati-
are EXPERTS of their own condition. They do, however,
onal cooperation, above all about my trusteeship in FH
not compete with science or the medical community -
Europe, the European FH Patient Network, which will
they are EQUAL partners. By joining forces with science
then be presented separately by FH Europe President
& clinicians, they start a fruitful dialog. They give scien-
and Heart UK CEO Jules Payne.
39
POSTER PRESENTATIONS –
SUBMITTED ABSTRACTS
P1.01. USING ONLINE PROGRAM OF GOOD NUTRITION AND WRIGHT DIET:
PREVENTION AND PART OF THE TREATMENT OF OBESITY AND CARDIOVASCULAR
DISEASES
V. Krylov
 [email protected]
LLC Right Diet, Moscow, Russian Federation
Objective: It is too much easier and cheaper to pre-
and 100 patients control group who were given the
vent obesity, than in the future to treat it’s complica-
same recommendations on the appointment. Persis-
tions.
tent decrease in body weight by an average of 6.5 kg
L. G. Porciuncula1,2, E. Esposo1, K. Ang1, K. Yap1
 [email protected]
1
St. Luke‘s Medical Center, Quezon City, Philippines, 2HB Calleja Heart and Vascular Institute, Quezon City, Philippines
Objectives: To validate the American College of Sur-
22 (7.7%) patients, pneumonia in 11 (3.8%) patients,
gery, National Surgical Quality Improvement Program
major cardiac event 1 (0.3%) patient, urinary tract
(ACS NSQIP) in predicting risk for developing major
infection in 4 (1.4%) patients, venous thromboem-
cardiovascular event (MACE) peri-operatively.
bolism in 1 (0.3%) patient, renal failure in 4 (1.4%)
patients, and return to operating room in 3 (1%). Average length of hospital stay was 4.76 (SD 5.22) days.
Design: Prospective cohort validity study.
The purpose of this study was to compare the RCRI
over six months was demonstrated in all patients of
Setting: St. Luke’s Medical Center, Quezon City,
and ACS NSQIP risk stratification in predicting risk for
Methods: We used an online system for patient
the main group, we also found it out that systolic and
November-December 2015.
MACE of patients undergoing non cardiac surgeries.
education based on the video lessons, full of humor,
diastolic blood pressure levels decreased more than 9
pictures, and cartoons to convey the necessary infor-
mm Hg, the consumption of milk and dairy products
Participants: All patients 18 years old and above,
ACS-NSQIP based on specificity and AUC. RCRI exhi-
mation on good nutrition, necessary to do exercises
increased by 2.6 times, compared with patients in the
with
infarction
bited a sensitivity of 100% and specificity of 98%,
and the need for exposure to the sun to our patients.
control group. The exposure to the sun was observed
documented as present on admission, given dual
corresponding to a positive likelihood ratio of +57, a
15 to 30 minutes daily, compared with the control
anti-platelets and anticoagulation.
PPV of 17% and a NPV of 100%. ACS-NSQIP showed a
RCRI showed better accuracy indices compared to
ST-segment-elevation
myocardial
sensitivity of 100% and specificity of 92%, correspon-
Results: Watching the short movies, the patients
group 5-10 minutes. Regular physical activity was in
formed the habits of good nutrition during the first
the main group of 260 minutes per week, in control
Main outcome measures: Main outcome measures
ding to a positive likelihood ratio of +12.8, a PPV of
month already, which includes a diet with restriction
group 80 minutes.
were occurrence of cardiac and non cardiac morbidi-
4.4% and a NPV of 100%. ACS-NSQIP risk index is a
ties within 30 days of admission: mortality, morbidity,
reliable preoperative assessment tool to identify
patient who have low risk for MACE.
of fat, digestible carbohydrates and daily consump-
40
P1.02. PROSPECTIVE VALIDATION OF AMERICAN COLLEGE OF SURGEON QUALITY
IMPROVEMENT PROGRAM RISK SCORE IN PREDICTING MAJOR CARDIOVASCULAR
EVENTS PERI-OPERATIVELY
tion of low-fat dairy products, slow carbohydrates,
Conclusions: Mobile and wireless technology helps
major cardiac events, pneumonia, surgical site infecti-
protein and fiber. Were also presented recommenda-
physicians to combat obesity and be a part of the tre-
on, urinary tract infection, venous thromboembolism,
tions for compliance with the physical activity, as well
atment of Diabetes Mellitus and Cardiovascular disea-
and renal failure.
as vitamin D consumption. A patient was in touch with
ses and we need to improve the quality of information
a doctor-endocrinologist. We examined data from a
material, including using online technologies to im-
Results: Among 286 patients, in-hospital death
ring in detecting mortality, cardiac and non-cardiac
survey of 500 patients registered in the online system
prove the quality and duration of life of our patients.
occurred in three (1%) patients, major morbidity in
morbidities.
Conclusion: Based on this study, the ACS NSQIP risk
scoring has better predictive ability than RCRI risk sco-
41
P1.03. VISCERAL ADIPOSITY CALCULATOR FROM THE DALLAS HEART STUDY:
POPULATION BASED RISK ESTIMATOR FOR VISCERAL ADIPOSE TISSUE
AND ASSOCIATED CARDIOVASCULAR RISK
P1.04. IMPACT OF A MULTIDISCIPLINARY LIFESTYLE INTERVENTION
DURING THE AGE OF GROWTH
C. Ranucci, V. Gianfredi, R. Pippi, C. Aiello, L. Buratta, N. Piana, E. Reginato, A. Tirimagni, E. Chiodini, E. Sbroma, A. Gili, P. De Feo,
C. Mazzeschi
 [email protected]
università degli studi di Perugia, Perugia, Italy
U. Akhtar, N. Kondamudi, C. Ayers, I. J. Neeland
 [email protected]
UT Southwestern Medical Center, Dallas, TX, United States
Background: Visceral adipose tissue (VAT) is a stron-
Discussion: The predictors of VAT noted in our model
Introduction: Childhood obesity is one of the most
for six months for children and three months for ado-
ger risk factor for insulin resistance, type 2 diabe-
are consistent with the literature. Those commonly
serious public health problems in our time. The pre-
lescents. Before and after the intervention, several
tes, hypertension, and cardiovascular disease than
linked to VAT in prior studies include WC, TG/HDL,
vention and the treatment of childhood obesity is
anthropometric measures (height, body weight, Body
subcutaneous adipose tissue. Although VAT can
race, and age, which at times show an interdependent
complex and requires a multi-component approach
Mass Index, waist circumference, waist-to-height
be accurately measured using dedicated imaging
relationship. These past studies were mainly limited
involving the family and addressing individual and
ratio, body composition) and nutrition habits of the
techniques such as CT or MRI, implementation of the-
to unidimensional analysis. The strength of our model
social aspects. The purpose of the present study is
participants and their families were evaluated. In
se modalities remains limited in clinical practice due
lies not only in the utilization of a larger, more diverse
to examine the impact of a multidisciplinary lifestyle
addition, a set of functional motor fitness tests was
to high cost, radiation exposure, and prolonged scan
population than prior studies, but also in the incorpo-
intervention to treat overweight/obese children and
performed to evaluate the aerobic capacity, speed,
time. We used data from the Dallas Heart Study to cre-
ration of a wide breadth of clinically expedient varia-
adolescents on: (1) changes in body composition; (2)
flexibility and dynamic muscle strength.
ate a clinically feasible surrogate model for VAT.
bles. Our study provides a model that can be incor-
adherence to a Mediterranean diet; and (3) physical
porated as a surrogate for VAT into risk stratification
performance. The lifestyle intervention for children
Results: After the intervention both children and
paradigms.
and adolescents has been designed with a multi-com-
adolescents significantly reduced their BMI, waist cir-
cardiovascular disease underwent measurement of
ponent family-based approach, it is based on the ex-
cumference, WHTR and fat mass, and improved fat
anthropometrics, laboratory data, and VAT by MRI
perience of the C.U.R.I.A.Mo. model, already experi-
free mass, adherence to the Mediterranean diet and
between 2000-2002. Sex-specific, multivariable back-
mented for adult obesity.
physical fitness performance. Conclusion: The results
Methods: 2,319 participants without diabetes or
wards elimination models were created to optimize
of this multidisciplinary intervention are encouraging
the clinical prediction of VAT and validated through
Materials and Methods: The study involved 74 over-
regarding the effectiveness in the short term in ame-
bootstrapping.
weight/obese children (aged 5-12) or adolescents
liorating the health status and the nutrition habits of
(aged 13-17). The intervention was multidisciplinary
children and adolescents. It remains to demonstrate
Results: Mean age of the cohort was 44 years with
including nutrition, exercise and psychological as-
the long-term efficacy of the intervention.
55% women and 46% African-Americans. The variab-
pects and a family-based approach; it was delivered
les included in the final model for women were age,
weight circumference (WC), TG/HDL, black race, and
serum glucose, and for men were age, WC, TG/HDL,
black race, and serum uric acid. The adjusted R2 was
0.64 for women, and 0.69 for men (P < 0.0001).
42
43
P1.05. PUBLIC PERCEPTION OF THE INTRODUCTION OF A SUGAR-SWEETENED
BEVERAGE TAX IN TRINIDAD: A CARIBBEAN PERSPECTIVE
P1.06. EFFECTS OF A TWO-YEAR ADDITIONAL PHYSICAL EDUCATION CLASS
INTERVENTION ON CHANGES IN MOTOR SKILLS IN ELEMENTARY SCHOOL
CHILDREN
K. D. Rocke, A. Garib, A. Ramcharitar-Bourne, S. D. Nichols, N. O. Dalrymple
 [email protected]
The University of the West Indies, St. Augustine, Trinidad and Tobago
R. Hauer, H. Tschan
 [email protected]
Universitiy of Vienna - Centre for Sport Science, Vienna, Austria
Introduction: Sugar-sweetened beverages have beco-
sing (28%). A 5% increase was most favourable among
Introduction: Physical inactive children are two times
Conclusions: Resent research already shows the im-
me a target of anti-obesity initiatives because of in-
participants. Higher BMI (OR= 1.06; 95% CI= 1.01, 1.11;
as likely to be obese as adults [3]. Nevertheless, only
portance of PA and the resulting health benefits for
creasing evidence of their link to obesity. Few studies
p=0.009) and consumption of non-sweetened bever-
a small number of children fulfill the physical activity
children. The preliminary results of this study give
have explored attitudes towards sugar sweetened
ages (OR= 1.39; 95% CI= 1.17, 1.65; p=<0.001) were
(PA) recommendations. Several research indicate that
evidence that PETH can play an important role to
beverage (SSB) taxation, with none to date at the local
more likely to be significantly associated with greater
more school sport can have positive effects in child-
improve physical development in elementary school
level. This study therefore sought to investigate the
support of the SSB tax. Those who were earning a
ren physical development [1, 2]. Therefore, the aim
children.
public’s perception of an introduction of such a tax in
monthly income of <$5.000 Trinidad and Tobago Dol-
of this current pilot study is to analyze the effects of
Trinidad.
lars (TTD) and consuming higher quantities of sweete-
additional physical education teaching hours (PETH) in
References: [1] Augste, C. & Künzell, S. (2014) J Sports
ned non-alcoholic and alcoholic beverages were sig-
elementary school children.
Sci., 32 (5), 415-423. [2] Reed, K. et al. (2008) Preven-
Materials and Methods: A cross-sectional study of
nificantly associated (p<0.001) with opposition to the
800 adults (aged >18 years) was conducted in Trini-
implementation of the SSB tax.
dad. Perception of the introduction of an SSB tax and
tive Medicine, 46, 525-531. [3] Nike, Inc. (2013). DesiMethods: In addition to regular PETH two additional
gned to move report.
hours were added per week for an intervention class
other correlates were assessed using self-administe-
Conclusion: Overall the public was undecided on the
(INT). Two times during the school year, children mo-
red questionnaires. Predictors of support and opposi-
implementation of an SSB tax. Although the introduc-
tor abilities were tested using the German Motor Test
tion to the tax, such as beverage consumption and so-
tion of such a tax appeared to be relatively favourab-
(DTM). This test evaluates strength, speed, coordina-
cio-demographic and lifestyle factors were explored
le among the general public, consideration must be
tion, endurance and flexibility. All collected data for
using multinomial logistic regression models.
given to sociodemographic, lifestyle and behavioural
the first two years have been compared to an equal
factors. Public consultation with public health officials,
control class (CON). Additionally, test results of the
Results: Most participants were neither in support nor
international organizations, the government and the
INT were compared with standard values for the DTM.
in opposition of the introduction of an SSB tax (42%),
general public is needed to ascertain the acceptance
Statistical significance was set at p ≤ 0.05.
followed by those in support (30%) and those oppo-
of introducing such a public health policy at the local
level.
Results: At baseline, the INT had significant better
values in strength, coordination and flexibility than
the CON. On the other hand, CON showed significant
better endurance results than INT. After one year of
intervention, INT still had significant better values, but
also showed an improvement in endurance with significant better results than CON. Similarly, after two
school years of intervention children showed higher
results for strength, coordination and flexibility compared to standard values.
44
45
P1.07. SUSTAINABLE LIFESTYLE. THE SIZE OF THE ECOLOGICAL FOOTPRINT
IN RELATION TO BODY MASS
P1.08. PSYCHOLOGICAL ASPECTS OF EATING BEHAVIOR AND MOTIVATION FOR
PHYSICAL ACTIVITY IN VIENNESE ADOLESCENTS
L. Heim, Z. Lelovics
 [email protected]
Kaposvár University, Kaposvár, Hungary
T. Vlasak1, J. P. A. Aden1, A. Bunina1, Z. Kovacovsky1, C. Pöppelmeyer2, K. Widhalm2
 [email protected]
1
Sigmund Freud University Vienna, Vienna, Austria, 2Austrian Academic Institute for Clinical Nutrition, Vienna, Austria
Background: Al Gore pointed out that global warming
Results: When calculating the ecological footprint the
The age range of the middle-aged youth is not only
Results: An analysis of the results in the field of physi-
is caused by the combination of various human
average score was 370 ± 72 points, corresponding to
characterized by the analysis of development tasks
cal acitivity showed that 15.1% of the examined adole-
activities, thus nutrition and lifestyle are among those
6.0-7.8 hectares. Overweight participants reached lo-
but also by the formation and solidification of the per-
scents rarely do sports for fun and pleasure. I addition
influencing factors.
wer (363 ± 74 points), while underweight participants
sonal health behavior. This particular context raises
to this the results of the examined adolescents are be-
(372 ± 77 points), participants with optimal body
the question in which extent young people are affec-
low average. Moreover the results showed that about
Aims: Assessing the ecological footprint of the
weight (372 ± 72 points) and obese participants (379 ±
ted by dysfunctional behaviors regarding the lifestyle
18% of the sample have an above-average depen-
population of Somogy County in relation to the body
60 points) reached higher scores. The difference was
factors „eating behaviour“ and „physical activity. Star-
dence on overeating and snacking and only a small
mass index (BMI, WHO 2007). Comparing and asses-
not significant in any of the cases. The footprints cor-
ting from an understanding of positive health, that the
possibility of control in situations of craving. In addi-
sing the differences of the ecological footprint among
responding with the scores are not dependent on BMI
promotion of functional settings and custom patterns
tion, 16.2% of young people have an above-average
people with optimal body mass and overweight/obese
(6.0-7.8 hectares as well).
is prioritized, an analysis of the status quo of young
tendency to increased eating in emotional situations..
people was found to be advisable. In the present stu-
people.
Conclusions: Since the 1992 Conference in Rio the
dy therefore aspects and behaviors with respect to
Conclusion: Considering the results some loss-ma-
Materials and methods: The authors used Eric Krau-
desired sustainable consumption behavioral patterns
diet and exercise for both of overweight affected, as
king behavior patterns of young people in dealing
se’s calculating method with an anonymous voluntary
are included among the international harmonization
well as non-affected children and young people are
with exercise and diet can be displayed, suggesting
self-completed ecological footprint questionnaire
topics. Among the topics, besides waste management
analyzed and relevant information is derived there-
interventions. Nevertheless the study pointed out re-
(n = 267; 36.5% male, average age 27,0 ± 8.5 years).
and energy saving issues nutritional and food proces-
from.
sources in the field of cognitive control on which can
The ratio of the participants with optimal body mass,
sing related activities are also included. Based on our
overweight and obese participants were 67.4%; 18.7%
results, using the given examination method, there
Method: In a sample of n = 118 adolescents aged 11
and 5.2% respectively (18,5 ≥ BMI 8.6%). In the valid
is no significant difference among the different BMI
to 13 were measured by AD-EVAs (Ardelt Gattinger &
assessment there are three questions concerning the
categories.
Meindl, 2010) the FEV-Salut-S, the FEV-Path-S, the FEV-
nutritional habits, dealing with the frequency of meat
be built upon in the future.
Path-EE, FEV Path -K and FUN.
and fish consumption and the purchasing attitudes of
homemade and domestic/local foods.
46
47
P1.09. RELEVANCE OF FAMILY SITUATION FOR HABITUAL EATING BEHAVIOUR
AND ITS IMPLICATIONS FOR THERAPEUTIC INTERVENTION MEASURES
P1.10. COMPARISION OF PHYSICAL ACTIVITY BETWEEN EDDY YOUNG PARTICIPANTS
AND STANDARD VALUES
J. P. A. Aden1, K. Koller1, A. Mayer1, C. Pöppelmeyer2, K. Widhalm2
 [email protected]
1
Sigmund Freud University Vienna, Vienna, Austria, 2Austrian Academic Institute for Clinical Nutrition, Vienna, Austria
T. Knopf1, R. Hauer2, C. Pöppelmeyer1, H. Tschan2, L. Stocker2, S. Gattermeyer3, A. Bunina3, J. P. A. Aden3, O. Pachinger4, K. Widhalm1
 [email protected]
1
Austrian Academic Institute for Clinical Nutrition, Vienna, Austria, 2Centre for Sport Science and University Sports, Vienna, Austria,
3
Sigmund Freud University Vienna, Vienna, Austria, 4Austrian Heart Foundation, Vienna, Austria
Background: Due to an increasing rate of obesity in
(32.6%) more often than children who live with a sing-
Introduction: The prevalence of overweight and obe-
Results: The results indicate that in comparison to the
child- and young-adulthood, the need for intervention
le parent (TV: 21.1%; Fastfood: 47.4%; Sweets: 10.5%;
sity has reached alarming rates in the European Uni-
standard value 22.5% where average, 11.3% above
measures is rising as well. As for the emergence and
Between 15.8%) or those who live with their grandpa-
on and the numbers are still rising (Wolf-Dietrich, et
average and 46.5% where below average. 2.8% of the
maintenance of adiposity and overweight, three fac-
rents (TV: 5%; Fast Food: 40%; Sweets: 20%; Between:
al., 2006). A study in Germany found out that obesi-
subjects where highly above average and 16.9% highly
tors seem to be crucial: Biological, psychological and
5%). This means, that even though children living with
ty as a disease is found in 48% of all schoolchildren.
below average.
social factors. With examining the family situation of
their parents show lower BMI percentile on average
Overweight children have a high risk to become over-
a child’s caretakers, the implications on the eating be-
(MD=75.8) than children living in different housing
weight adults with a high risk for the occurrence of
Discussion: The results are showing that more than
haviour and selected anthropomorphic markers can
situations (grandparents: MD=81.45; single parent:
type 2 diabetes, cardiovascular, orthopedic, and other
the half of the subjects are below average. Therefore
be elicited.
MD=84.1) the parenting styles of the latter seem to
diseases (Wabitsch, 2004). The aim of this study is to
it is important to raise awareness of a healthy nutriti-
discipline the children’s eating behaviour in a stricter
raise awareness and to prevent children to get over-
on and increase physical activity already in early age.
way.
weight individuals.
The present study will continue two more years and
res, the data used is collected in form of questionnai-
Discussion: Especially the organisation of eating hab-
Methods: Regarding methodology section this study
res, which examines children’s eating behaviour, the
its differs in each of the family situations. Primarily the
follows a qualitative research including the German
amount of different foods they eat, as well as their
single parent households as well as the households in
motorik test which is tailored for children and adole-
knowledge about a healthy diet. The sample consists
which grandparents take part in parenting show res-
scence (http://www.sport.kit.edu/dmt/). The subjects
of N=174 children between the age from seven to
trictive and strict forms of organisation. Intervention
had to follow 8 different sport tasks. The test is made
nine.
measures integrating the family surroundings should
from the German institute of sport and sport sciences.
therefore take account to the different conditions and
The evaluation of the test was done with the program
requirements of the diverse family situations.
regarding to the test. The sample of this study inclu-
Methods: The present abstract uses data from the
“Eddy-Projekt. Apart from anthropomorphic measu-
Results: Children who are living with both their parents eat more often in front of the TV (51.1%), pre-
5 more tests will show if the prevention program of
Eddy Young achieves success.
des 71 children which are between 8 and 10 years old.
fer fast food to a greater extent (68.9%) and also eat
sweets after meals (39.3%) as well as between meals
48
49
P2.01. WAIST CIRCUMFERENCE AND WAIST-TO HEIGHT RATIO PREDICT SODIUM
INTAKE AMONG CARIBBEAN ADULTS
K. D. Rocke, S. D. Nichols, N. O. Dalrymple, A. Ramcharitar-Bourne
 [email protected]
The University of the West Indies, St. Augustine, Trinidad and Tobago
P2.02. FASTING HYPERGLUCAGONEMIAIS ASSOCIATED WITH GLUCOSE INTOLERANCE,
HIGH PLASMA TRIGLYCERIDES AND VISCERALADIPOSITY IN OBESE CHILDREN
AND ADOLESCENTS
H. Manell1,2, H. Kristinsson1, J. Kullberg3, K. Paulmichl4,5, J. Staaf1,6, J. Cadamuro7, F. Zsoldos4,5, S. Göpel8, E. Sargsyan1, H. Ahlström3,
D. Weghuber4,5, A. Forslund6, P. Bergsten1
 [email protected]
1
Dept. of Medical Cell Biology, Uppsala University, Uppsala, Sweden, 2Dept. of Women’s and Children’s Health, Uppsala University,
Uppsala, Swaziland, 3Dept. of Surgical Sciences, Radiology, Uppsala University, Uppsala, Sweden, 4Department of Pediatrics,
Paracelsus Medical University, Salzburg, Austria, 5Obesity Research Unit, Paracelsus Medical University, Salzburg, Austria, 6Dept. of
Women’s and Children’s Health, Uppsala University, Uppsala, Sweden, 7Dept. of Laboratory Medicine, Paracelsus Medical University, Salzburg, Austria, 8AstraZeneca R&D, Mölndal, Syrian Arab Republic
Introduction: Habitual high levels of sodium intake
be 3.107 ± 44.41 mg/day. Sodium intakes adjusted for
may be linked to the development of hypertension
age, gender, calories, family history of hypertension,
and diabetes mellitus - contributors to over 50% of
diabetes mellitus, heart disease, and BMI were posi-
annual visits to healthcare facilities in the Caribbean.
tively associated with waist circumference and waist-
Overweight and obesity remain consistent risk factors
to-height ratio. Elevated waist circumference (females
for these conditions. In this study, we examined the
> 34 inches; males >40 inches) and waist-to-height
Introduction: Type 2 diabetes (T2D) development
by magnetic resonance imaging. These associations
association between anthropometric indices of over-
ratio (≥0.5) were associated with high sodium intake
in children and adolescents is a growing health con-
were independent of BMI, age, gender and family
weight and obesity and sodium intake.
(>2400 mg/day) - odds ratio (OR); 1.38; 95% CI 1.02,
cern and the connection between obesity and T2D is
history of diabetes. Exposure of human islets to 0.5
1.87; p<0.05) and 1.28; 95% CI 1.01, 1.64; p<0.05) res-
well established. Recently, elevated glucagon levels
mM palmitate doubled glucagon secretion at fasting
pectively. BMI was not associated with sodium intake.
have attracted more attention as contributing factor
glucose concentrations.
Materials and Methods: A cross-section of residents
completed a structured self-administered questi-
to development of the disease but glucagon release
onnaire consisting of demographic, health history
Conclusions: It this study, elevated waist circumferen-
patterns in children and adolescents with obesity are
Summary: Collectively, this demonstrates a connec-
and food frequency items. Dietary sodium intake was
ce and waist-to-height ratio were associated with high
poorly investigated.
tion between fasting hyperglucagonemia and increa-
obtained using a food frequency questionnaire cont-
sodium intake. Persons in this population with eleva-
aining 120 items which were analysed for sodium and
ted central adiposity may be at an increased risk for
Methods: Here we investigated fasting circulating le-
adolescents with obesity, where the glucagonotropic
calories. Anthropometry was self-reported. Partici-
conditions associated with high sodium intakes.
vels of glucagon and lipids in children and adolescents
effect of fatty acids is a potential underlying mecha-
pants giving both oral and written consent were en-
with obesity and lean controls and glucagon secretion
nism.
rolled in the study. Participation was voluntary.
from isolated human islets exposed to fasting glucose
sed visceral adiposity and blood lipids in children and
concentrations and elevated concentrations of fatty
Results: Two thousand, three hundred and forty-three
acids observed in children with obesity.
individuals (females = 1.277; males = 1.066) participated in the study. Mean sodium intake was found to
Results: In children and adolescents high fasting
plasma glucagon was associated with high BMI, waist
circumference, 2-hour plasma glucose, fasting HbA1c,
insulin and triglycerides and low HDL-cholesterol.
Elevated fasting glucagon levels were also associated
with large visceral adipose tissue volume, quantified
50
51
P3.01. WHICH IS THE BEST BIOMAKER TO PREDECT CARDIOVASCULAR EVENTS IN THE
APPARENTLY HEALTHY JAPANESE OBESE POPULATION?: C-REACTIVE PROTEIN,
URINE ALBUMIN, B-TYPE NATRIURETIC PEPTIDE, AND GLOMERULAR FILTRATION
RATE
P3.02. THE RELATIONSHIP BETWEEN SERUM URIC ACID AND LEFT VENTRICULAR
HYPERTROPHY IN OVERWEIGHT AND OBESE CHILDREN
Y. Matsuura1, M. Honma1, S. Takahashi1, F. Tanaka1, K. Tanno1, K. Sakata1, A. Okayama2, M. Nakamura1
 [email protected]
1
Iwate Med Univ, Morioka, Iwate, Japan, 2Research Institute for Lifestyle-Related Disease Prevention, Tokyo, Japan
B. Bjelakovic1, N. Kavaric2, G. Kocic3, A. Klisic4, M. Jovic3, L. Saranac1, T. Jevtovic-Stoimenov3
 [email protected]
1
Clinic of Pediatrics, Clinical Center, Nis, Serbia, Medical faculty, University of Nis, Nis, Serbia, 2Primary Health Care Center, Podgorica, Montenegro, Podgorica, Montenegro, 3Medical faculty, University of Nis, Nis, Serbia, 4Primary Health Care Center, Podgorica,
Montenegro, Montenegro, Serbia
Background:
protein
Results: The mean follow up period of the study was
Introduction: Except dyslipidemia, insulin resistance,
Results: We found statistically significant correlation
(hsCRP), B-type natriuretic peptide (BNP), urinary al-
8.8 years. The hazard ratios for CVE onset in terms
and autonomic disbalance, metabolic syndrome also
between the serum concentration of the uric acid and
bumin (UA) and estimated glomerular filtration rate
of per 1SD increment (as a continuous variable) and
encompasses chronic systemic inflammation. As the
index of the myocardial mass (r=0.33, p=0.03) as well
(eGFR) have been suggested to be useful predictors
values above the 80th percentile (as a categorical
one of the most important endogenous metaboli-
as between uric acid and RWT (r=0.4 p=0.005) in all
for the development of cardiovascular events (CVE) in
variable) for each biomarker level were determined
te with a protective anti-inflammatory, uric acid has
children. After controlling for body mass index, only
the general population. However, it remains unknown
(Table). In addition, the area under the curve of ROC
attracted scientific attention in the last decade. The
correlation between RWT and uric acid persisted
which biomarker is the most useful predictor for CVE
analysis for CVE prediction for hsCRP (95% CI; 0.637 -
practical clinical question is to define the relationship
(r=0.287 p=0.05).
specifically in the apparently healthy obese populati-
0.711) was significantly higher than those of the other
between the uric acid and cardiac hypertrophy in obe-
on.
biomarkers (95% CI; 0.536 - 0.616).
se children. The aim of the study was to examine the
Conclusion: We can conclude that serum uric acid
relationship between serum uric acid concentration
concentration in overweight or obese children, corre-
High
sensitivity
C-reactive
Methods: Obese subjects as defined by BMI more
Conclusion: Increased levels of hsCRP are superior to
and left ventricular (LV) geometry in overweight and
late with relative wall thickness but not left ventricular
than 30 (n=642, mean age 62, women 81%) were rec-
BNP, eGFR or UACR for risk assessment for the future
obese children with or without metabolic syndrome.
mass index.
ruited from the Japanese general population. Baseline
onset of CVE in apparently healthy obese subjects.
blood levels of BNP and hsCRP, and UA corrected by
Patients and methods: In a retrospective study a to-
urinary creatinine (UACR), and estimated GFR were
tal of 48 overweight or obese children were examined
determined. Admission cases of CVEs (composite
Apart from the standard laboratory analyses, body
endpoint; myocardial infarction or stroke) were pro-
mass index and serum uric acid concentration were
spectively recorded by the regional registration. For
measured. To define left ventricular geometry we
each biomarker, a multivariate Cox regression analy-
also determined myocardial mass index by M-mode
sis adjusting for traditional risk factors (age, sex, BMI,
echocardiography using Devereux formula indexed
hypertension, diabetes, hyperlipidemia, atrial fibrilla-
by body hight as well relative wall thickness (RWT) de-
tion, smoking) was performed to examine the relative
fined as LV wall thickness + septal thickness relative to
risk for new onset of CVE.
the internal dimensions of the LV .
Hazard Ratio* per 1SD
increment (95%CI)
p-value
Hazard Ratio* above 80
percentile (95%CI)
p-value
hsCRP
1.54 (1.15-2.08)
0.001
3.88 (1.88-8.00)
0.004
BNP
1.28 (0.84-1.97)
0.748
0.88 (0.40-1.95)
0.252
eGFR
1.16 (0.75-1.80)
0.122
3.43 (0.72-16.35)
0.494
UACR
1.45(0.82-2.55)
0.116
1.75 (0.87-3.50)
0.196
*Hazard ratios were adjusted for age, sex, BMI, diabetes, hypercholesterolemia, Af, hypertension and smoking.
52
53
P3.03. SCREENING OF NUTRITIONAL STATUS OF MARFAN SYNDROME PATIENTS
A. Kiss1, Z. Lelovics2
 [email protected]
1
Szent István University, Budapest, Hungary, 2Kaposvár University, Kaposvár, Hungary
P3.04. AN OVERVIEW OF THE BODYWEIGHT IN VIENNESE PRIMARY SCHOOL CHILDREN:
FIRST RESULTS FROM THE EDDY YOUNG STUDY
C. Pöppelmeyer1, J. P. A. Aden2, O. Helk1, O. Pachinger1, K. Widhalm1
 [email protected]
1
Austrian Institue for Clinical Nutrition, Vienna, Austria, 2Psychological Department Sigmund Freud University Vienna, Vienna, Austria
Introduction: Marfan syndrome is a genetic disorder
loss is also 8.8%. We found that the effect of acute ill-
of the connective tissue, which affects approximately
nesses on the malnutrition risk is 10.5%. The rate of
Overweight and obesity are rising problems in Euro-
higher than the percentage of extremely under-
2.000-3.000 individuals in Hungary. It is multi-syste-
overweight is twice as often among men than women,
pe. Therefore the WHO declared the prevention of
weight boys (2.1%). In total 6.8% of the girls and 4.2%
mic manifestations, this disorder is often difficult to
(25.0 ≤ BMI < 30.0), on the whole the rate of over-
overweight as a high priority research aim. The EDDY
of the boys are underweight. About a quarter of the
diagnose. To date, the National Marfan Register sys-
weight is 30.7%. The rate of obesity (30.0 ≤ BMI < 40.0)
Young study is an interventional cohort study in Vien-
male participants (24.2%) and 15.9% of the femal sub-
tem contains approximately 250 cases. Our goal is to
is equal among man and woman (7.0-7.0%). The
nese primary school children which aimes to achieve a
jects have an increased waist circumference. In total
assess the nutrition and nutritional status of Hungari-
authors didnt cope extreme obes (40.0 ≤ BMI)
sustainable change in eating habits and physical activi-
18.6% of the subjects have increased body fat (girls:
an patients suffering from Marfan syndrome.
Marfan-syndrome patients during the study.
ty to combat obesity and its consequences. Anthropo-
12.2%, boys 24.2%). First anthropometric data from
metric data from n=183 primary school children aged
the EDDY YOUNG study indicate a rising prevalence
Materials and Methods: We screened in 2014 the nutritional status of 114 voluntary Marfan-syndrome
Conclusions: Based on the reference of the European
6-11 years were collected by bioimpedance analysis.
of overweight and obesity in Austrian primary school
patient elder than 18 years with the validated Malnu-
Union, national health care systems need to attend
Additionally height as well as waist and hip circumfe-
children. The percentage of overweight is significant-
trition Universal Screening Tool (MUST), and with the
particularly to the recognition of rare diseases, and to
rence was measured. In our sample 37.5% of the sub-
ly higher in comparison to the data of the previous
Food Frequency Questionnaire for valid nutritional
the development of patient treatment. The screening
jects are overweight or obese. On the other hand 5.5%
EDDY Study in 11-14 aged adolescents (+12.9%). No-
status assessment.
nutritional status of Marfan syndrome patients also
of the subjects are classified as underweight or mas-
table is the considerable amount of 19.7% obese sub-
provides new opportunities to study Hungarian pati-
siv underweight (3.3%). The gender-specific analysis
jects (previous EDDY Study: 6%). The results underline
Results: According to our results the risk of malnu-
ents with Marfan syndrome. To reduce the prevalen-
shows that the overweight is more pronounced in the
the importance of establishing successful prevention
trition for these people is high (25.5%), but the pre-
ce of malnutrition important to screen the nutritional
boys (43.2%) that in the girls (31.8%). In particular the
concepts to influence young childrens lifestyle and ea-
valence of the malnutrition depends on the assessed
status. Along malnutrition the problems of overweight
amount of obese is considerably higher in the boys
ting behavior with permanent age- appropriated lifes-
and number of those parameters. The proportion of
and obesity are a danger to medical condition of Mar-
(25.3%) than in the girls (13.9%), whereas the percen-
tyle interventions starting in primary school.
malnutrition among people according to their Body
fan syndrome patients.
tage of extremely underweight girls (4.5%) is clearly
Mass Index is 12.3%, and according to their weight
54
55
P3.05. LIFESTYLE, ENVIRONMENTAL, AND DIETARY FACTORS AFFECTING OBESITY RISK
IN 10-YEAR-OLD CHILDREN AND 14-YEAR-OLD ADOLESCENTS
E. Malina-Altzinger1, J. P. A. Aden2, E. Ponocny-Seliger2
 [email protected]
1
Austrian Academic Institute for Clinical Nutrition, Vienna, Austria,
2
Psychological Department Sigmund Freud University Vienna, Vienna, Austria
P3.06. BMI AND QUALITY OF LIFE IN ADOLESCENCE
Z. Kovacovsky, B. Stetina, J. P. A. Aden, A. Bunina, E. Ponocny-Seliger
 [email protected]
Psychological Department Sigmund Freud University Vienna, Vienna, Austria
Objective: Childhood and adolescent overweight and
Results: Results indicate a statistically significant
obesity have increased substantially over the past two
relationship between BMI and QoL in adolescents.
Background: A large-scale study undertaken in
Results: As part of a binary logistic regression, a com-
decades, raising concerns about the biopsychosocial
It shows that the higher the measured BMI the lower
cooperation between the Medical University of Vien-
prehensive model with a total of 18 predictors was
consequences. RQ: Association between body mass
the documented quality of life (girls (r=-.213; p=.009)
na (MUW), Sigmund Freud University of Vienna (SFU),
used to anticipate obesity. Here, the predictors of
index (BMI) and health-related quality of life (QoL).
and boys (r=-.211; p=.004)), resulting in e.g. little joy in
and the Vienna School Supervisory Board focused on
“sedentary lifestyle”, “implementation of suggestions
the topic of „lifestyle, environmental, and dietary fac-
in the field of sports” and “junk-food parents” pro-
Research Methods and Procedures: A nationally
not being able to eat what they want and suffering
tors affecting obesity risk in 10-year-old children and
ved to be significant. A path model was subsequently
representative sample of 410 adolescents (aged 13-
from being mocked about their appearance.
14-year-old adolescents „. It gave rise to the following
created. It in turn supported the direct influence of
16) completed demographic and standardized tests
research question: „Which familial, psychological,
“sedentary lifestyle” as significant for obesity. There
including the Subtest “Skala zur Lebensqualität in
Discussion: The presented results underline once
and lifestyle factors have significant impact on body
is also a pattern of interaction between the “eating ha-
Bezug auf Adipositas von Kindern und Jugendlichen”
more the importance of healthy bodyweight in
weight among 14-year-old adolescents?“
bits of young people” and the “food preferences of the
(SLQ-Adip). The adolescent self-reported height and
adolescence age.
parents”, which demonstrates a reciprocal influence.
weight were used to calculate the BMI (kg/m2). Statistical analysis included exploratory methods.
Materials & Methods: Questionnaires were quanti-
Discussion: The results imply that both lack of exer-
tatively evaluated from a total n=401 female (51.7%)
cise and „junk food“ consumption by parents signi-
and male (48.3%) students from different schools.
ficantly influence obesity rates among cohabiting
A Mayring qualitative content analysis was used for
adolescents. Parental nutritional choices are also as-
the analysis of the two focus groups, each consisting
sociated with adolescents own dietary behavior. The
of 10. Our social-science approach took the form of
analyses of the focus groups additionally suggest that
a series of questionnaires for pupils, the Depression
eating habits and body-awareness and perception are
Inventory for Children and Adolescents (DIKJ) and the
closely linked to the social environment. Adolescents
Obesity Evaluation Questionnaire (AD-EVA).
are very aware of evaluation and comparison criteria
exercising, annoyance about not fitting into clothes,
and see these also as a reference for self-assessment.
56
57
P3.07. LIFE MODIFICATION TREATMENT OF METABOLICSYNDROME IN
SCHOOLCHILDREN WITH HIGH RISK ATHEROSCLEROTIC FAMILY HISTORY
T. Szamosi, P. Goltl, A. Sragner, D. Torok, A. Szabo
 [email protected]
2nd Pediatric Department, Medical Faculty, Semmelweis University, Budapest, Hungary
P4.01. HOW DID AN ALBINO PATIENT LOSE 148 LBS OF WEIGHT? A CASE REPORT
Z. Shah1, S. Montanagh2, S. Rizvi3
 [email protected]
Liaquat University of Medical and Health Sciences Jamshoro, Pakistan, Thatta, Pakistan, 2Ankara University School of Medicine,
Ankara, Turkey, 3R-Endocrinology, Hamilton, NJ, United States
1
Metabolic syndrome of schoolchildren with high risk
the family possibilities and the lack of any smoking
INTRODUCTION: Obesity is a highly prevalent and
DISCUSSION: Obesity needs to be treated as any
atherosclerotic family history was described by us
controlled by nutritionists, physical exercise teachers
yet the most neglected disease. The number of over-
other complex disease. We observed Orlistat and
earlier when significant parameters were detected.
and medical doctors. Some patients finished the care
weight and obese people reached 2.3 billion and 700
Liraglutide to be safe and effective in reducing obesi-
Overweight was one of more significant parameters.
period after 2 years, others finished after 3 years. Our
million worldwide respectively, by the year 2015. Obe-
ty. Substantial literature has emerged to show that in
The investigation of the effect of 2-3 years long life
results showed that after the care period the above
sity is not a social disgrace but an actual disease with
both Occulocutaneous albinism and Prader-Willi syn-
modification treatment containing diet, physical exer-
mentioned risk factors were no more detected in 615
a major genetic component to its etiology. Weight
drome (the most common genetic cause of obesity)
cise and no smoking advices on metabolic syndrome
girls and 573 boys. Significant improvements were ob-
reduction medications should be used as an adjunct
the P gene is mutated on Chromosome 15. This high-
of schoolchildren with high risk atherosclerotic family
served in further 136 girls and 98 boys. Systolic blood
to diet restriction, exercise and behavioral modifica-
lights the genetic susceptibility of our albino patient
background is the objective of this paper. Patients
pressure and overweight have normalized earlier and
tions. We hereby present a case of a morbidly obese
for developing morbid obesity.
were 872 girls and 715 boys aged 6-17 years having
much more time was necessary for the improvement
male patient with occulocutaneous albinism who has
three from the following symptoms: serum triglyceri-
of non alcoholic fatty liver disease. No any changes
lost 148 lbs of weight. Furthermore, the report high-
CONCLUSION: Obesity develops from the interplay
de level above 1.1 or 1.4 mmol/L due to age, plasma
were detected in 121 girls and 44 boys because of
lights the genetic link between occulocutaneous alb-
of both genetic and environmental factors. This case
insulin level above 20 IE, serum HDL-cholesterol level
the lack of cooperation or other especially endocrine
inism and obesity.
clearly illustrates that Orlistat and Liraglutide can be
below 0.9 mmol/L, systolic blood pressure above 95
illnesses. We concluded that the life modification tre-
centiles according to the age and height, body mass
atment seems to be useful weapon against metabolic
CASE PRESENTATION: 28-year-old male with occu-
Scientific research in the genetic aspects of obesity
index above 95 centiles, non alcoholic fatty liver disea-
syndrome observed in schoolchildren with high risk
locutaneous albinism presented with 361.8 lbs of
can help develop new strategies towards its preven-
se. The method contained advices about the low fat,
atherosclerotic family background if the cooperation
weight (BMI: 62.1) and complaint of difficulty in losing
tion and treatment.
low salt, no refined sugar, high fiber and high antioxi-
among health services, families and their children is
weight. Lab investigations showed unregulated hyper-
dant diet, daily physical exercise accommodated for
ensured.
lipidemia and hypotestosteronemia. The patient was
safe and efficient for weight loss in morbid obesity.
prescribed Orlistat 120 mg. Over the period of five
years, he lost 83.8 lbs. After this time, Orlistat’s effectiveness was significantly reduced. Consequently, the
patient was started on Liraglutide on which he lost 64
lbs in three years. Thus, a sum of 147.8 lbs of weight
was lost without any side effects of the drugs.
58
59
P4.02. TRPM8 INDUCED INCREASE IN ENERGY EXPENDITURE: ENDOCRINOLOGICAL
EVIDENCES AND THERAPEUTIC IMPLICATION IN OBESITY AND ASSOCIATED
COMPLICATIONS
P. Khare1,2, P. Mangal3, K. K. Kondepudi1, S. S. Sharma4, K. K. Bhutani3, K. Chopra2, M. Bishnoi1
 [email protected]
1
National AgriFood Biotechnology Institute (NABI), Mohali, India, 2Pharmacology division, University Institute of Pharmaceutical
Sciences (UIPS), Panjab University, Chandigarh 160014, India, 3Department of Natural Products; National Institute of Pharmaceutical Education and Research (NIPER), Mohali, India, 4Department of Pharmacology and Toxicology; National Institute of Pharmaceutical Education and Research (NIPER), Mohali, India
P4.03. PANCREATIC LIPASE INHIBITION: DIETARY INTERVENTION & PREVENTION OF
OBESITY AND HIGH FAT DIET INDUCED METABOLIC COMPLICATIONS
P. Mangal1, P. Khare2, K. K. Bhutani1
 [email protected]
1
National Institute of Pharmaceutical Education and Research, SAS Nagar, Mohali, India,
2
2National Agri-Food Biotechnology Institute (NABI), S.A.S. Nagar, Mohali, India
Introduction: Obesity and associated co-morbidities
Results and discussion: Oroxylin A was found to in-
have emerged as most challenging health problem
hibit 69.86 ± 2.96% of PL enzyme at the dose of 250
Background: Obesity and its associated complications
Interestingly, TRPM8 agonist also increased serum
and become a leading cause of death worldwide.
μg/mL. Acute dose of oroxylin A in LTT prevented the
have become a global health concern. Excess energy
glucagon concentration which was blocked by specific
Excessive fat absorption and accumulation is the main
absorption of oral lipid load and supported it’s PL
intake and less physical activity have been considered
and non specific TRPM8 antagonists. In agreement,
cause of obesity. Pancreatic lipase (PL) enzyme plays
inhibitory potential. Further, oroxylin A supplemen-
as a root cause of weight gain and associated co-mor-
chronic menthol administration increased liver glu-
a major role in digestion of dietary fat and its absorp-
tation prevented HFD induced weight gain in in vivo
bidities. Energy expenditure of the body is a natural
coneogenesis and reduced liver glycogen content in
tion. Therefore, intervention in dietary fat absorption
mouse model for obesity. Total serum cholesterol and
phenomenon which can be increased to treat meta-
HFD fed mouse. Importantly, these observed changes
by PL enzyme inhibition of could be a preventive mo-
triglyceride levels were also normalized in oroxylin A
bolic disease. Aim of the present work is to explore
were independent of sympathetic activity.
del for obesity.
supplemented group. Therefore, all the above results
melastatin 8 (TRPM8) channel in enhancing energy
Conclusion: Our finding suggests the role of TRPM8
Material and methods: In vitro pancreatic lipase (PL)
expenditure of the body and to prevent obesity and
in diversion of ingested energy from storage to ex-
inhibition assay was performed to evaluate anti-obe-
associated complications.
penditure via TRPM8 dependent mechanisms. Hence,
sity potential of oroxylin A, isolated from Oroxylum
Conclusion: In vitro and in vivo effects of oroxylin A
TRPM8 modulators can be developed as a preventive/
indicum bark. Further, HFD fed mouse model for obe-
against fat absorption suggests the role of PL enzyme
Methods: In vitro and in vivo experiments were per-
therapeutic tool for obesity and associated complica-
sity was used to evaluate in vivo anti-obesity potential
in obesity development and give a new avenue to tre-
formed in 3T3L1 cell lines and swiss albino mice res-
tions.
of oroxylin A. Lipid tolerance test (LTT) was performed
at the obesity and concomitant diseases.
supported potential of oroxylin A against obesity and
the role of cold-sensing transient receptor potential
to evaluate the inhibitory effect of oroxylin A on die-
pectively. Acute and chronic studies were done using
different agonist and antagonists of TRPM8 channel.
Acknowledgement: Department of Biotechnology,
tary fat absorption. Oral glucose tolerance test and
Oral glucose tolerance test, histology of liver and adi-
Government of India for providing research grant and
other relevant experiments were also performed to
pose tissue, serum hormonal levels, gene expression
fellowship
check potential of oroxylin A against obesity associa-
and biochemical studies in different tissues were per-
its associated co-morbidities.
ted metabolic complications.
formed. Chemical sympathetic denervation was carried out using 6OHDA.
Results: Chronic menthol (prototype TRPM8 agonist)
co-administration along with energy dense food in
mouse prevented weight gain, insulin resistance and
hepatic steatosis via increase in energy expenditure,
activation of mitochondria and generation of “brite”
cells in white adipose tissue. Increased energy expenditure is also shown by other TRPM8 agonist and blocked by specific and non specific TRPM8 antagonist.
60
61
P4.04. FUNCTIONAL COBIOTIC TEA AMELIORATES OBESITY ASSOCIATED
COMPLICATIONS BY PREVENTING GUT DYSBACTERIOSIS IN MICE
NOTES
D. P. Singh1,2, K. K. Kondepudi1, K. Chopra2, M. Bishnoi1
 [email protected]
1
National Agri-food Biotechnology Institute (NABI), SAS Nagar, Mohali, Punjab, India,
2
University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India
Background: Palatable energy dense foods consump-
Results: GTE, IMOs and their cobiotic combinations
tion not only precipitates obese phenotype but also
prevent HFD induced obese phenotype and associ-
altered the gut microbiome diversity. It promotes me-
ated metabolic complication, leaky gut, metabolic
tabolic endotoxemia, ectopic fat deposition and low
endotoxemia and systemic inflammation along with
grade systemic inflammation. Here we evaluate the
decreased beneficial microbial populations in gut. In
effects of novel cobiotic concept based functional tea
particular, combination of the two agents (cobiotic)
(combination of green tea extract and isomalto-oligo-
has shown synergistic/additive effects.
saccharide) on high fat diet (HFD) induced alterations
in mice via improving gut bacterial composition.
Conclusion: Strategically chosen food based components when combined (functional cobiotic tea) for
Design: Male Swiss albino mice were fed with HFD
the systemic up-frontation against the HFD induced
(58% fat kcal) for 12 weeks. Systemic adiposity and ec-
alterations, could be developed as a novel class of
topic fat deposition, gut lining derangement and V3-
functional foods against obesity and associated com-
V4 region based 16S rRNA metagenomic sequencing,
plications.
systemic and tissue inflammation along with gene
expression analysis were done in mice supplemented
with green tea extract (GTE), isomalto-oligosaccharide
(IMOs) or their cobiotic combination.
62
63
AUTHOR INDEX
A
Aden, J. P. A.: P1.08, P1.09, P1.10, P3.04,
P3.05, P3.06
Ahlström, H.: P2.02
Aiello, C.: P1.04
Akhtar, U.: P1.03
Ang, K.: P1.02
Ayers, C.: P1.03
B
Bergsten, P.: P2.02
Bhutani, K. K.: P4.02, P4.03
Bishnoi, M.: P4.02, P4.04
Bjelakovic, B.: P3.02
Bunina, A.: P1.08, P1.10, P3.06
Buratta, L.: P1.04
C
Cadamuro, J.: P2.02
Chiodini, E.: P1.04
Chopra, K.: P4.02, P4.04
D
Dalrymple, N. O.: P1.05, P2.01
De Feo, P.: P1.04
Dieplinger, H.: 6.1
E
Esposo, E.: P1.02
F
Flodmark, C. E.: 5.7
Forslund, A.: P2.02
G
Garib, A.: P1.05
Gattermeyer, S.: P1.10
Gianfredi, V.: P1.04
Gili, A.: P1.04
Goltl, P.: P3.07
Göpel, S.: P2.02
Grillich, L.: 5.5
H
Hanauer-Mader, G.: 7.5a
Hauer, R.: P1.06, P1.10
Heim, L.: P1.07
Helk, O.: 5.6, P3.04
Honma, M.: P3.01
J
Jevtovic-Stoimenov, T.: P3.02
Jones Bell, M.: 3.3
Jovic, M.: P3.02
64
K
Kavaric, N.: P3.02
Khare, P.: P4.02, P4.03
Kiss, A.: P3.03
Klisic, A.: P3.02
Knopf, T.: P1.10
Kocic, G.: P3.02
Koller, K.: P1.09
Kondamudi, N.: P1.03
Kondepudi, K. K.: P4.02, P4.04
Kostner, G. M.: 7.4
Kovacovsky, Z.: P1.08, P3.06
Kristinsson, H.: P2.02
Krylov, V.: P1.01
Kullberg, J.: P2.02
L
Lelovics, Z.: P1.07, P3.03
Lissau, I.: 5.3
Lobstein, T.: 2.1
M
Malina-Altzinger, E.: P3.05
Manell, H.: P2.02
Mangal, P.: P4.02, P4.03
Matsuura, Y.: P3.01
Mayer, A.: P1.09
Mazzeschi, C.: P1.04
Montanagh, S.: P4.01
Moreno, L. A.: 5.4
N
Nakamura, M.: P3.01
Neeland, I. J.: P1.03
Nichols, S. D.: P1.05, P2.01
O
Okayama, A.: P3.01
P
Pachinger, O.: 5.6, 6.2, P1.10, P3.04
Paulmichl, K.: P2.02
Payne, J.: 7.5b
Pecoraro, L.: 5.1
Piana, N.: P1.04
Pietrobelli, A.: 5.1
Pippi, R.: P1.04
Ponocny-Seliger, E.: P3.05, P3.06
Pöppelmeyer, C.: 5.6, P1.08, P1.09,
P1.10, P3.04
Porciuncula, L. G.: P1.02
Pushkarev, N.: 1.4
R
Rabmer-Koller, U.: 1.2
Ramcharitar-Bourne, A.: P1.05, P2.01
Ranucci, C.: P1.04
Reginato, E.: P1.04
Rizvi, S.: P4.01
Rocke, K. D.: P1.05, P2.01
Roillet, M.: 4.2
KEYWORD INDEX
S
Sakata, K.: P3.01
Saranac, L.: P3.02
Sargsyan, E.: P2.02
Sbroma, E.: P1.04
Schätzer, M.: 4.7
Schwandt, P.: 6.3
Shah, Z.: P4.01
Sharma, S. S.: P4.02
Simon, J.: 3.2
Singh, D. P.: P4.04
Sragner, A.: P3.07
Staaf, J.: P2.02
Stefanutti, C.: 7.3
Stetina, B.: P3.06
Stocker, L.: P1.10
Szabo, A.: P3.07
Szamosi, T.: P3.07
T
Takahashi, S.: P3.01
Tanaka, F.: P3.01
Tanno, K.: P3.01
Tirimagni, A.: P1.04
Torok, D.: P3.07
Tschan, H.: 2.2, P1.06, P1.10
V
Visscher, T. L. S.: 4.5
Vlasak, T.: P1.08
w
Warschburger, P.: 2.3
Weghuber, D.: 3.4, P2.02
Widhalm, K.: 5.6, 7.1, P1.08, P1.09, P1.10,
P3.04
Y
Yap, K.: P1.02
Z
Zsoldos, F.: P2.02
A
ACS NSQIP risk score: P1.02
adolescents: P1.08, P3.06
atherosclerotic family history: P3.07
Austrian Social Security Institutions: 1.2
B
body mass index: P3.06
C
cardiovascular diseases: 6.1, 6.2
Caribbean: P2.01
central adiposity: P2.01
Childhood obesity: P1.04, P3.04
Cholesterol Charity: 7.5b
cobiotic tea: P4.04
community based: 4.2
D
Dallas Heart Study: P1.03
Denmark: 5.3
development: P1.06
diet: P1.01
dietary factors: P3.05
dietary pattern: 4.7
eating behavior: P1.08, P1.09
E
Economic aspects: 3.2
EDDY: 5.6
Endocrinology: P4.02
Energy Expenditure: P4.02
EPHA: 1.4
epidemiological data: 6.1
epidemiology: 2.1
EPODE: 4.5
F
familial hypercholesterolemia: 7.1
family situation: P1.09
fat absorption: P4.03
food systems: 1.4
G
glucose intolerance: P2.02
gut dysbacteriosis: P4.04
H
health related quality of life: P3.06
heart study: 6.3
hyperglucagonemia: P2.02
I
inequality: 2.1
innovation: P1.01
Italy: 5.1
L
lifestyle intervention: 5.5, P3.04
Lifestyle Regimen: 3.4
Lifestyle: P1.04, P1.07, P3.05
Lipid lowering drugs: 7.3
Lipoprotein Apheresis: 7.3
Liraglutide: P4.01
V
Viasano: 4.2
Vienna: 5.6
Visceral adipose tissue: P1.03
Visceral adiposity calculator: P1.03
visceral adiposity: P2.02
M
major cardiovascular event: P1.02
malnutrition: P3.03
Marfan-syndrome: P3.03
metabolic synd: P3.02, P3.07
multidisciplinary approach: P1.04
N
Nationwide initiative: 4.7
New Drugs: 7.4
Nutrition: 3.4
nutrition-related knowledge: 4.7
O
obesity prevention: 1.4, 3.3
Obesity: 2.1, P3.03, P3.05, P4.01, P4.02,
P4.03
online: P1.01
Orlistat: P4.01
P
Pancreatic lipase inhibtion: P4.03
Patient Organizations: 7.5a
performance: P1.06
Physical Activity: 2.2, P1.10
physical: P1.06
Prevention: 6.2
Psychological aspects: 2.3
psychology: P1.08
R
relative wall thickness: P3.02
S
school based intervention: P3.04
Screening: P3.01
sodium intakes: P2.01
Spain: 5.4
Stroke: P3.01
sugar-sweetened beverages: P1.05
Sustainable: P1.07
Sweden: 5.7
T
tax: P1.05
The Ecological Footprint: P1.07
Trinidad: P1.05
U
uric acid: P3.02
65
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