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Hormone Action Cloze Use your Cornell Notes, Figure 13.5 (p. 488) and Figure 13.7 (p. 490) to complete the sentences. There are two types of Hormone Action. They are classified as either ______________________or _________________________. Steroid Hormone Action Once secreted by the endocrine gland, a steroid hormone crosses a target cell ____________________. Once it enters the cell, it combines with a _____________________ __________________. This receptor is either in the ___________________ or ______________________of the cell. The hormone and the protein receptor combined is called the ________________ ________________ ____________. This activates ____________________of mRNA molecules from DNA. The mRNA strand of molecules leave the nucleus and enters the _____________________________ and begins the process of ______________________ ___________________. These newly synthesized proteins produce a hormone’s _____________________effects. Nonsteroid Action Once secreted by the endocrine gland, a nonsteroid hormone is carried by _______________ ____________ to the _______________________ _________________. The hormone binds to the ______________________ on the cell membrane of its target cell. The ____________protein is activated, which then activates molecules of the enzyme _______________ ____________________. This converts ATP into ______________________ _____________________ ____________________, also known as cAMP. cAMP activates __________________ ____________________. Protein kinases are enzymes that modify other proteins by chemically adding phosphate groups to them. Phosphates provide _________________. The ________________________processes of the cell changes as a result, which produce the hormone’s ______________________. Extend your knowledge for 5 Extra Credit Points! What is the difference between a 1st and 2nd messenger in hormone action?