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Hear and now: Chinese Health in NZ Michelle Wong ENT Surgeon, ADHB Population statistics • 2013 Census: – 4.24 Million Kiwis – 170,667 Chinese • Life Expectancy born today (non-Maori): – Males 80 years – Females 84 years • Life Expectancy of 65 year-old (non-Maori): – Males 84 years – Females 86.5 years Population by Age 2013 350000 300000 250000 200000 150000 Total NZ Chinese 100000 50000 0 0-4 5-9 10-14 15-19 20-24 25-29 30-34 35-39 40-44 45-49 50-54 55-59 60-64 65-69 70-74 75-79 80-84 85 Years Years Years Years Years Years Years Years Years Years Years Years Years Years Years Years Years Years And Over Chinese Population by age 2013 20000 18000 16000 14000 12000 10000 8000 6000 4000 2000 0 0-4 5-9 10-14 15-19 20-24 25-29 30-34 35-39 40-44 45-49 50-54 55-59 60-64 65-69 70-74 75-79 80-84 85 Years Years Years Years Years Years Years Years Years Years Years Years Years Years Years Years Years Years And Over Chinese Chinese HEARING Health in NZ • Population of baby boomers and elderly on the increase • Newborn Hearing Screen • Increasing Migrant population from China • Bilingual: hearing and tonal languages UNHS around the World United States United Kingdom Screening > 3.5 million babies per year. Screening 600,000/yr by March 2005 Australia Screening >100,000 babies per year In New Zealand • 135- 170 children / year ( 3/1000 births) with PCHI • Identification ( 2003): – Average age 3-4 years – Maori 80% by 80 months age ( 6.7 years) – Others 80% by 60 months age ( 5 years) • Evidence for the importance of early identification of hearing loss • Critical period= first 6 months of life Vocabulary Range at 3 years of age: Normal hearing Vocabulary Range (Marion Downs, 1997) 1000 No. words 800 600 75th percentile Median 25th percentile 700+ words 400 200 0 Normal At birth 6mths Age of Identification 2 years Vocabulary Range at 3 years of age: Identified at birth Vocabulary Range (Marion Downs, 1997) 1000 No. words 800 75th percentile Median 25th percentile 600 400 350 words 200 0 Normal At birth 6mths Age of Identification 2 years Vocabulary Range at 3 years of age: Identified at 6 months Vocabulary Range (Marion Downs, 1997) 1000 No. words 800 75th percentile Median 25th percentile 600 400 200 words 200 0 Normal At birth 6mths Age of Identification 2 years Vocabulary Range at 3 years of age: Identified at 2 years Vocabulary Range (Marion Downs, 1997) 1000 No. words 800 75th percentile Median 25th percentile 600 400 200 0 Normal At birth 6mths Age of Identification 2 years Begin pre-school with less than 50 words in their vocabulary. Adjusted Mean Total Language Quotient Even when picked up in the first 12mths they don’t do significantly better. 100 80 60 40 20 0 0-6 7-12. 13-18. 19-24. 25-34 It is not until intervention begins in the first 6mths there Age of Identification (Months) is a significant improvement. Mean language quotient by age of identification From:Yoshinago-Itano et al (1998) HIEDI • 2001 Hearing Impairment, Early Detection and Intervention formed in NZ • 2006 government announces national funding for Newborn Screening program • NZ 1 July 2007 rolled out over 3 years – 20 DHBs – Self governance UNHSEIP- aims: • 1. Babies to be screened by 1 month age • 2. Audiology assessment completed by 3 months age • 3. Initiation of appropriate medical and audiological services and Early Intervention education services, by 6 months of age How do you screen for a baby’s hearing? Infant diagnostic test battery Tympanometry Otoacoustic Emissions (OAE’s) Auditory Brainstem Response ( ABR) (Distortion Product) Otoacoustic emissions ( DPOAE) Otoacoustic Emissions (OAE’s) Debris in the ear canal. Fluid behind the eardrum. Click stimulus Pass Result OAE testing probe placed in the ear canal Within the cochlear The “emission” from the Outer Hair Cell travels out the ear & is picked up by the probe. Fluid & debris can block the stimulus getting in AND block the response coming out = Higher Refer rates. Outer Hair Cells Outer hair cells contract in response to the sound. DPOAE’s The most prominent emission is “2F1- F2” If F1=1000Hz.and F2=1200Hz., then 2F1-F2=2(1000)-1200=800Hz.) (Automated) Auditory Brainstem Response, AABR Automated Auditory Brainstem Response (AABR) If built up enough fluid & debris can still increase the refer rate because it blocks the sound getting into the ear. BUT This doesn’t occur as much as with OAE because the recording is not being made back through the ear canal. Auditory Brainstem Response (ABR) AABR screening tests the response of the hearing nerve & brainstem. AABR tests beyond both the Inner & Outer hair cells. Automated Auditory Brainstem Response (AABR) PASS result AABR Template built into the screener (statistical rather than an actual waveform) 35dB AABR – What happens with a restless baby? Refer result The sensors pick up the muscle movement, which are much larger than the ABR response. This distorts the waveform & it can’t match up to the template/black box algorithm. 35dB 1. Exclusion criteria – Age range: • <34 weeks or greater than 6mths old. 6 months old: < 34 weeks gestation A baby > 6mths old has a more mature brain & faster response, which the template is NOT designed for. A baby <34 weeks has a less mature Brain and more delayed response which the sample is not designed for. Normal AABR template for 34 weeks to 6mths of age. New Zealand’s testing protocol The incident • July 2012 – ADHB lead screener told by parents of a baby she was about to screen that the baby had already been screened, but was not recorded. • One report from ADHB • Audit of screener: – 1 July 2011- 11 July 2012 – 1044 babies screened by screener – 145 babies had screening in one ear twice – 183 babies had screening in one ear with one ear of screener – 103 babies who had results recorded from the screener recording her own ear results Cochlear implants Chinese Kid Some facts about China • Universal Newborn Hearing Screening (UNHS) has been implemented in China since 1999. • By 2010 UNHS was implemented in 20 of the 32 Chinese provinces. • In large cities 95% of babies are screened in hospital-based programs. • In more remote areas babies with high-risk factors for hearing loss are referred to screening centres within 1 month of birth and leaflets about identifying deafness are distributed. Some facts about China and CI • Since 1995 more than 10 000 people in China have received cochlear implants (CIs) • 85% of these implant recipients have been children under the age of 7 years • CI penetration in China is currently less than 5% of potential pediatric candidates, • Cochlear implantation is continuing to expand at great speed, and it is hoped that the infrastructure and capacity will continue to grow and develop. Some numbers of interest • 1990: 6 million ‘totally deaf people’1 • 2008: 21 million people with hearing loss 2 • 2000: WHO estimated prevalence of hearing loss3 – Childhood onset: 0.12% (hearing threshold in better ear is 61-80 dB HL) – Childhood onset: 0.1% (hearing threshold in better ear Is >81 dB HL) – Adult onset: 1.3% (hearing threshold in better ear is 61-80 dB HL) – Adult onset: 0.3% (hearing threshold in better ear is >81 dB HL) – ~24.5 million people with a severe to profound hearing loss in China Tonal languages ~ 88 languages in the world have ‘complex’ tone system (more than 3 tones) – shown in red dots Fundamental Frequency (F0) Six lexical-tones of / wɐi /, Cantonese Tone 1 威 (smart) Tone 4 圍 (surround) Tone 2 委 (appoint) Tone 5 偉 (huge) Time Tone 3 餵 (feed) Tone 6 胃 (stomach) Fundamental Frequency (F0) Six lexical-tones of / wɐi /, Cantonese Tone 1 威 (smart) Tone 4 圍 (surround) Tone 2 委 (appoint) Tone 5 偉 (huge) Time Tone 3 餵 (feed) Tone 6 胃 (stomach) 4 lexicial tones /ma/, Mandarin /ma/ 160 F 140 F0 (Hz) H H R 120 R L 100 F mother hemp horse to scold [Tone 1] L 80 0 25 50 Time (%) [Tone 2] 75 100 [Tone 3] [Tone 4] Outcomes with CI • Two large scale outcomes studies in China – still ongoing • The preliminary data from the studies indicate that the performance of Mandarin-speaking CI children is comparable to that of US children with CIs. • Although the results of studies on CI outcomes of Mandarin-speaking children showed variable outcomes, it is evident that the majority of children benefited from CI intervention. Investigation of cortical and subcortical plasticity following short-term unilateral auditory deprivation in normal hearing adults • 11 adults ( 21-50 years), normal hearing • Left custom-fitted silicone plug for 7 days ( equivalent to a mild high freq hearing loss) • fMRI 3.0T was performed just after plug inserted and 7 days later; stimulus was a noise burst to evoke cortical activity Hearing loss in the elderly