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2014 Pancreatitis Pancreatitis What is the pancreas? The pancreas is a flat-shaped gland that lies behind your stomach. Pancreas What does the pancreas do? • The pancreas makes the enzymes that are needed to digest the fats, proteins, and carbohydrates we eat. A duct (tube) that runs the length of the gland delivers the enzymes to the duodenum (the beginning of the small bowel). • There are special cells, the islets of the pancreas, which secrete insulin and glucagon into the bloodstream. They control your blood sugar level. 1 What is pancreatitis? The term ‘pancreatitis’ means inflammation of the pancreas. There are 2 types of pancreatitis, acute and chronic. Chronic pancreatitis This is a long-term condition that causes scarring and permanent damage to the pancreas. The main symptoms are pain, weight loss, and loss of pancreas tissue (possibly causing diabetes and poor nutrition). Acute pancreatitis This is when there is a sudden onset of symptoms and it is the most common type of pancreatitis. 2 Acute Pancreatitis What causes acute pancreatitis? The most common cause in adults is gallstones. Alcohol abuse is next. You may have more than one attack but usually recover fully after each one. Less common causes of acute pancreatitis are: • A viral infection • An accident or physical injury • Handling of the pancreas at the time of surgery or ERCP (Endoscopic retrograde cholangiopancreatography procedure) • Some medications • Elevated blood triglyceride levels • A defect (physical problem) in the structure of pancreas or intestine In about 15% of cases the cause is unknown. In pancreatitis, the enzymes that are normally secreted for food digestion can attack the pancreas. This is called autodigestion. There may be bleeding into the pancreas causing swelling, serious tissue damage, infections, and cysts. In severe cases, the enzymes and toxins may enter the blood stream and seriously injure organs such as the heart, lungs, and kidneys. Intense, painful symptoms may last for hours to days. About 20% of cases are severe. 3 What are the symptoms of acute pancreatitis? The main symptoms are pain in the upper abdomen or back, and nausea. Acute pancreatitis comes on suddenly. It can vary from mild to life-threatening. It usually goes away in a week or so. Severe cases may have major complications such as infection, hemorrhage (heavy bleeding), failure of other organs, or fluid collections in the abdomen (called pseudo cysts). The pseudo cysts often go away on their own. Large cysts that last for more than 6 weeks are usually drained to prevent further problems. How is acute pancreatitis diagnosed? • Your doctor will find that the abdomen is tender. • During acute attacks, high levels of amylase and lipase are found in the blood. Amylase and lipase are digestive enzymes made in the pancreas. • A CT scan or ultrasound may show swelling or damage to the pancreas, or fluid collecting around the pancreas. 4 What is the treatment for acute pancreatitis? • You may need to stay in the hospital to treat the vomiting and pain with intravenous (IV) fluids, electrolytes, and pain medication. • Tests will be needed to find the cause of the pancreatitis. If the pancreatitis is due to gallstones, your doctor will recommend removing your gallbladder. • You will be watched closely for complications. • Patients with severe symptoms may need care in an Intensive Care Unit (ICU) or an Intermediate Care Unit (IMCU). • Surgery may be needed if a pancreatic infection develops. In most cases, your symptoms will go away in 4-7 days. Around then, you can start to drink fluids on your own and be discharged from hospital. Can acute pancreatitis be prevented? In most cases, the answer is no. Precautions to avoid some types of pancreatitis: • Avoid alcohol. • If you have diabetes or high cholesterol, follow your treatment plan. 5 Chronic Pancreatitis What causes chronic pancreatitis? Alcohol abuse causes 75% of chronic pancreatitis. Less common causes are: • Hereditary (passed down in families) pancreatitis • Obstruction (blockage) of the pancreatic duct In many cases, it is not possible to be sure of the cause. There is always irreversible scarring of the duct and of the function of the glandular tissue in the pancreas. What are the symptoms of chronic pancreatitis? The main symptom is pain. The pain is usually in the upper abdomen, and often spreads to the back. Attacks of pain last from hours to days, and may become continuous. Eating may increase the pain. There may be weight loss and foul (bad)-smelling bowel movements (stools). 6 How is chronic pancreatitis diagnosed? • There is often a history of pancreatitis. • There may be signs of poor nutrition and weight loss. • An abnormal CT scan or ultrasound may show inflammation and/or hardening of the pancreas. • Amylase levels may be elevated (higher). • A number of special tests are available to assess the function of the pancreas and enzyme secretion. How is chronic pancreatitis treated? • If a cause is found, it should be treated. • Stop drinking alcohol completely. • Pain relief is important. Referral to a chronic pain clinic may be helpful to find treatment options other than narcotics. • A low-fat diet should be followed. Take fat-soluble vitamins (A, D, and K) and calcium. • If you have pancreatic insufficiency, you may receive enzyme replacement. • If you develop diabetes, you may need insulin injections. 7 Are there any complications with chronic pancreatitis? Possible complications are: • Narcotic addiction • Obstruction (blockage) of the common bile duct • Pancreatic insufficiency • Diabetes What are the consequences of chronic pancreatitis? • Hospital stays • Social life and employment may be affected • Weight loss • Depression • Narcotic dependency if narcotics are needed for pain A variety of health care providers are often needed to manage your disorder. We hope we have explained what can and cannot be done for this condition. You will be able to work with your health care team to choose the best treatments for you. If you have any questions, please ask. We are here to help you. 8 Notes: Looking for more health information? Contact your local public library for books, videos, magazines, and other resources. For more information go to http://library.novascotia.ca Capital Health promotes a smoke-free, vape-free, and scent-free environment. Please do not use perfumed products. Thank you! Capital Health, Nova Scotia www.cdha.nshealth.ca Prepared by: Eleanor Griffiths RN, BScN, Nurse Educator Revised by: Clinical Nurse Educator, Hepatobiliary Surgery Illustration by: LifeART Super Anatomy 1 Images, Copyright © 1994, TechPool Studios Corp. USA Designed by: Capital Health Library Services, Patient Education Team Printed by: Dalhousie University Print Centre The information in this brochure is provided for informational and educational purposes only. The information is not intended to be and does not constitute healthcare or medical advice. If you have any questions, please ask your healthcare provider. WI85-1071 Revised September 2014 The information in this pamphlet is to be updated every 3 years.