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Cystoid Macular Edema (CME) Anatomy of the retina and macula Light enters the eye and is focused onto the retina, the light-sensing part of the eye. This information is transmitted though the optic nerve to the brain where it is interpreted as the images you see. The macula is the part of the retina responsible for your central vision. What is cystoid macular edema? Cystoid macular edema (CME) occurs when abnormal fluid accumulates in the macula. This results in retinal thickening and the presence of cyst-like fluid collections that distort the normal retinal architecture. CME can be caused by many different conditions including trauma, surgery, retinal vein occlusions and inflammation of the eye. CME commonly occurs after eye surgery. This is likely related to inflammation. About 1-3% of all cataract surgery patients will experience decreased vision due to CME, usually within a few months of surgery. Normal macula OCT www.houstonretina.com FA of macula with CME Normal FA 713.4. F A of macula with CM 4. F A OCT of macula with CME www.houstonretina.com 713.524.3434 or 800.833.5921 Disease Course & Treatment The most common symptoms of CME are blurred or distorted central vision. Other symptoms may include dim vision or decreased sensitivity to light. Sometimes patients may have no symptoms. Your ophthalmologist may obtain multiple types of ocular imaging including photography, ocular coherence tomography (OCT) and fluorescein angiography (FA) to facilitate diagnosis and treatment. Depending on the cause of CME, treatment may include some of the following: • Anti-inflammatory medications including steroid and/or non-steroidal anti-inflammatory medications in the form of eye drops, pills or intravitreal injections • Laser therapy • Intravitreal injections of anti-vascular endothelial growth factor medications • Surgery such as vitrectomy Diabetes, high blood pressure and poorly controlled cholesterol can make CME worse and more difficult to treat. These cardiovascular risk factors should be optimally controlled under the guidance of your primary care physician. Causes of CME include • • • • • Eye surgery Retinal vein occlusion Uveitis (inflammation of your eye) Eye trauma Side effects of some medication © 2011 Retina Consultants Houston Fortunately, most patients with CME can be successfully treated and vision often improves, although the healing process can be slow and take several months.