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Cystoid Macular Edema
(CME)
Anatomy of the retina and macula
Light enters the eye and is focused onto the retina,
the light-sensing part of the eye. This information is
transmitted though the optic nerve to the brain
where it is interpreted as the images you see. The
macula is the part of the retina responsible for your
central vision.
What is cystoid macular edema?
Cystoid macular edema (CME) occurs when abnormal fluid accumulates in the macula. This results in
retinal thickening and the presence of cyst-like fluid
collections that distort the normal retinal architecture.
CME can be caused by many different conditions including trauma, surgery, retinal
vein occlusions and inflammation of the eye. CME commonly occurs after eye surgery.
This is likely related to inflammation. About 1-3% of all cataract surgery patients will
experience decreased vision due to CME, usually within a few months of surgery.
Normal macula OCT
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FA of macula with CME
Normal FA
713.4. F A of macula with CM 4. F A
OCT of macula with CME
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713.524.3434 or 800.833.5921
Disease Course & Treatment
The most common symptoms of CME are blurred or distorted central vision. Other
symptoms may include dim vision or decreased sensitivity to light. Sometimes patients
may have no symptoms. Your ophthalmologist may obtain multiple types of ocular
imaging including photography, ocular coherence tomography (OCT) and fluorescein
angiography (FA) to facilitate diagnosis and treatment.
Depending on the cause of CME, treatment may include some of the following:
• Anti-inflammatory medications including
steroid and/or non-steroidal anti-inflammatory
medications in the form of eye drops, pills or
intravitreal injections
• Laser therapy
• Intravitreal injections of
anti-vascular endothelial growth
factor medications
• Surgery such as vitrectomy
Diabetes, high blood pressure and poorly controlled cholesterol can make CME worse and
more difficult to treat. These cardiovascular risk factors should be optimally controlled
under the guidance of your primary care physician.
Causes of CME include
•
•
•
•
•
Eye surgery
Retinal vein occlusion
Uveitis (inflammation of your eye)
Eye trauma
Side effects of some medication
© 2011 Retina Consultants Houston
Fortunately, most patients with CME can be successfully treated and vision often improves,
although the healing process can be slow and take several months.