Download Detailed Programme

16 – 19 May
DETAILED SCIENTIFIC
PROGRAMME
24 CME Credits of the Swiss Society of Clinical Pharmacology and Toxicology
The 37th Congress of the European Association of Poisons Centres and
Clinical Toxicologists (EAPCCT) has been organised by the following
Committees:
EAPCCT Scientific and Meetings Committee
Ana Ferrer Dufol, Chair
Mark Zammit, General Secretary
Nicola Bates, Abstract Editor
Lisa Breitner, Administrator
Régis Bédry
Pieter Brekelmans
Miran Brvar
Alexander Campbell
Paul Dargan
Michael Eddleston
Florian Eyer
Lotte Hoegberg
Knut Erik Hovda
Davide Lonati
Charles McKay
Bruno Mégarbane
Robert Palmer
Steven Seifert
Horst Thiermann
Martin Wilks
Sergey Zakharov
Pieter Brekelmans Miran Brvar
Patricia Casey
Paul Dargan
Ana Ferrer Dufol
Lotte Hoegberg
Peter Hultén Davide Lonati
Horst Thiermann
Geert Verstegen
EAPCCT Board
Bruno Mégarbane, President
Alexander Campbell, Past-President
Martin Wilks, President-Elect
Mark Zammit, General Secretary
Sergey Zakharov, Treasurer
Congress secretariat
Maria Cubí, 4 Pral
08006 Barcelona – Spain
[email protected]
SOCIAL PROGRAMME
Welcome Reception (included in congress registration) at Volkshaus Basel on Wednesday 17 May 2017
at 19:00 hrs. The Volkshaus Basel is located about 10 minutes’ walk from the Congress Center Basel at
Rebgasse 12-14, near Claraplatz. The new Volkshaus Basel, built in 1925, has been undergoing architectural
intervention by renowned architects Herzog & de Meuron to revitalize the diversity of uses to combine
cultural events, arts and gastronomy in one and the same building.
The Conference Dinner will be held in the historic guildhall (Zunftsaal) of the Restaurant Safranzunft located
in the centre of the Old Town of Basel near Marktplatz, 15 minutes’ walk or 10 minutes by tram from the
Congress Center at Gerbergasse 11 on Friday 19 May 2017 at 19:30 hrs (Swiss Francs 100). The noble Safran
Guild originated in the middle ages as one of the main four merchant guilds, amongst a total of twenty guilds
in Basel. Today Safran Guild is tasked with the care of maintaining the traditions it was built upon, and the
continued nurture and growth of relationships within the community.
Tickets can be bought at the registration desk. Tickets are limited in number by the venue, so please book
early to avoid disappointment.
PRE-CONGRESS SYMPOSIUM
Room Montreal, Tuesday 16 May 2017
Toxicological analysis and contribution to diagnosis and patient
management in clinical toxicology
Session chair: Bruno Mégarbane, Miran Brvar
09:00 - 09:30 Chromatographic techniques – applications for ethanol and toxic alcohol poisoning Ana Ferrer Dufol, Clinical University Hospital, Zaragoza, Spain
09:30 - 10:00 Mass spectrometry – applications and future development Olivier Laprévote, Université Paris Descartes, AP-HP, Paris, France
10:00 - 10:30 Development of library search-based screening system
Hans Maurer, Saarland University, Homburg (Saar), Germany
At the end of this session the audience should be able to:
• Describe the analytical principles involved in chromatographic techniques applied to
toxicological analysis and their usefulness as the gold standard for quantification of
alcohols with reference to the flame ionization detector (FID)-based technique for
follow-up of antidote treatment in methanol poisoning
• Explain how mass spectrometry compares to other methods for the toxicological
analysis of a patient
• Understand the relevance of drug screening approaches for clinical toxicology with
reference to the principles, advantages and limitations of target and library-based
screening approaches and their use in case-solving in clinical toxicology
10:30 - 11:00 Coffee
Session chair: Alex Manini, Carlo Locatelli
11:00 - 11:30 Tox analysis for new psychoactive substance screening in biological matrices: where do we stand today?
Markus R Meyer, Saarland University, Homburg (Saar), Germany
11:30 - 12:00 Metal detection assays for exposure diagnosis and monitoring
Souleiman EL Balkhi, Centre Hospitalier Universitaire de Limoges, Limoges, France
12:00 - 12:30 Tox analysis for risk assessment: methodological requirements
Michael G Holland, SUNY Upstate Medical University, Syracuse, USA
At the end of this session the audience should be able to:
• Evaluate the limitations of commonly available drug testing systems for analysis of
novel psychoactive substance (NPS) and describe alternatives, which might be used
• Recognise the circumstances where metals determination is useful or mandatory in
the diagnosis and management of exposure
• Describe the types of equipment used for real-time monitoring of an air contaminant,
how they work and what equipment is suitable for the various types of air contaminants
of interest (gases, particulates, etc)
12:30 – 13:30 Lunch
3
PRE-CONGRESS SYMPOSIUM
Room Montreal, Tuesday 16 May 2017
Toxicological analysis and contribution to diagnosis and patient
management in clinical toxicology (cont)
Session chair: Charles McKay, Daniela Pelclova
13:30 - 14:00 Tox analyses for substances of abuse and psychotropic drugs in the emergency room (ER)
Matthias Liechti, University Hospital Basel, Switzerland
14:30 – 15:00 Usefulness of toxicological analysis for the management of cardiotoxicant poisonings Bruno Mégarbane, Paris-Diderot University, Lariboisière Hospital, Paris, France
15:00 – 15:30 TOXI-triage - can pesticide and toxic alcohol exposure be diagnosed by breathalyzer
Michael Eddleston, University of Edinburgh, UK
At the end of this session the audience should be able to:
• Evaluate sensitivity and specificity of immunoassays and chromatographic methods
and their relevance in the ER setting
• Evaluate the benefits and limitations in the interpretation of the blood concentration
of a cardiotoxicant drug, if available, to manage a poisoned patient
• Explain the potential role of Gas Chromatography - Ion Mobility Spectrometry in
detecting toxic alcohol and pesticides in the breath of poisoned patients
15:30 – 16:00 Coffee
Session chair: Horst Thiermann, Alexander Campbell
16:00 – 16:30
Forensic toxicology - how to combine selectivity, sensitivity, and robustness
Stephen Morley, University of Leicester Hospital Trust, Leicester, UK
16:30 - 17:00 Hair analysis: when, how and why?
Pascal Kintz, X-Pertise Consulting, Strasbourg, France
17:00 – 17:30 Postmortem tox analysis: principles and interpretation
Thomas Kraemer, University of Zurich, Switzerland
17:30 – 18:00
Biomedical verification of chemical warfare agent exposure
Harald John, Bundeswehr Institute of Pharmacology and Toxicology, Munich, Germany
At the end of this session the audience should be able to:
• Evaluate the advantages and disadvantages of the range of analytical instruments
used by clinical and forensic toxicology laboratories
• Understand the interest of testing drugs in hair for historical monitoring
• Explain the differences between post-mortem analysis and analysis in a living person
• Describe the fate of chemical warfare agents (nerve and blister agents) in vivo
following the principles of biotransformation to form hydrolyzed agents and
proteins adducts that can be used as biomarkers detected by either GC-MS or LCMS/MS-based techniques
4
MAIN CONGRESS
Room Montreal, Wednesday 17 May 2017 (morning)
Plenary Lecture followed by Toxicology of Migration & Short Orals (1)
Session chair: Alexander Campbell, Ana Ferrer Dufol
08:55 – 09:00
Welcome and opening
Bruno Mégarbane, President EAPCCT
09:00 – 09:45
Public health aspects of the migrant crisis and the role of WHO
Joanna Tempowski, World Health Organization, Geneva, Switzerland
09:50 – 10:10 Rapid Risk Assessment of chemical/toxicological incidents with cross-border threats
to public health
Raquel Duarte Davidson, Public Health England, Chilton, UK
10:10 – 10:30 Incidents related to illegal importation of chemicals in the US
Michael Holland, SUNY Upstate Medical University Syracuse, USA
At the end of this session the audience should be able to:
•Discuss the key health problems facing migrants and measures that can be put in
place to manage these
•Understand the processes required for a rapid risk assessment of serious cross
border threats to public health from chemicals
•Describe incidences involving importation of illegal toxic chemicals into the US
10:30 – 11:10
Coffee and electronic posters
Session chair: Alvin Bronstein, Viorela Nitescu
11:10 – 11:30 Specific poisonings risks for migrants or caused by migrating poisons in Germany
Herbert Desel, Kathrin Begemann and Esther Feistkorn
At the end of this lecture the audience should be able to:
•Describe the specific poisoning risks for migrants arriving in Germany and the novel
risks for the population caused by increased import of foreign products to Germany
11:30
11:35 11:40 Poisonings involving refugees in Northern Germany during the migrant crisis, 2015-2016
(abstract no. 7)
Elke Färber, Rafael Wagner, Annette Groeneveld, Adrienne Kilian, Martin Ebbecke
University Medical Center, Göttingen, Germany
Exposures in refugees reported to the Poisons Information Centre Erfurt, 2007-2016
(abstract no. 8)
Germaine Frimlova, Helmut Hentschel, Dagmar Prasa, Mandy Gollmann, Gesine
Liebetrau, Bettina Plenert, Anne Stürzebecher, Michael Deters
Poisons Information Centre Erfurt, Erfurt, Germany
Two cases of ayahuasca poisoning: a poison crossing borders (abstract no. 9)
Mari A Bjornaas, Oona Dunlop, Dag Jacobsen
Oslo University Hospital Ulleval, Oslo, Norway
5
MAIN CONGRESS
Room Montreal, Wednesday 17 May 2017 (morning)
Short Orals (1) (cont)
11:45 12:25 - 12:30
Most amatoxin poisonings in Sweden occur in persons of non-Swedish background
(abstract no. 10)
Bengt Carlvik, Erik Lindeman
Swedish Poisons Information Centre, Stockholm, Sweden
Unusual mushroom poisoning in an immigrant: a case report (abstract no. 11)
Nena Golob, Mojca Dobaja, Miran Brvar
University Medical Centre Ljubljana, Ljubljana, Slovenia
Increased migration to Sweden and increased incidence of isoniazid poisonings
(abstract no. 12)
Lisa Franzén, Christina Didner, Peter Hultén
Swedish Poisons Information Centre, Stockholm, Sweden
Drugs crossing borders: unexpected dosing error with identical formulation of
prazepam (Lysanxia®) (abstract no. 13)
Jonas Moens, Martine Mostin
Belgian Poison Center, Brussels, Belgium
§ Occupational inhalation poisoning with the veterinary antibiotic tiamulin (abstract no. 14)
Mojca Dobaja (1), Lucija Sarc (1), Marija Jamsek (1), Darja Gnezda Mugerli (2), Bor Antolic (1),
Miran Brvar (1)
(1)
University Medical Centre Ljubljana, Ljubljana, Slovenia; (2) General Hospital “Dr.
Franca Derganca” Nova Gorica, Nova Gorica, Slovenia
Occupational-related fatal case of acute methyl ethyl ketone peroxide ingestion: case
report and review of the literature (abstract no. 15)
Yao-Min Hung (1), Te-Hao Wang (2)
(1)
Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; (2) Taipei Veterans General
Hospital, Taipei, Taiwan
Suspected metal fume fever from domestic exposure to lead fumes while making lead
sinkers in an enclosed space (abstract no. 16)
William PA Ryan (1), Andis Graudins (2)
(1)
Monash Health, Dandenong, Australia; (2) Monash Health and Monash University,
Dandenong, Australia
Descriptive study of an urban academic toxicology consultation service, 2012-2016
(abstract no. 17)
Kristin McCloskey, Ryan Surmaitis, David Goldberger, Rita McKeever, David Vearrier,
Zachary Schwartzkopf, Michael I Greenberg
Drexel University College of Medicine, Philadelphia, US
General discussion
12:30 - 14:00
Lunch and posters
§ Shortlisted for Taylor & Francis best case study award
11:50 11:55 12:00 12:05 12:10 12:15 12:20
6
MAIN CONGRESS
Room Singapore, Wednesday 17 May 2017 (morning)
Antidotes: Something Old, Something New, Something Borrowed,
Something Blue Session chair: Martin Wilks, Christopher Yates
09:50 – 10:10 New antidotal strategies for nerve agent poisoning
Horst Thiermann, Bundeswehr Institute of Pharmacology and Toxicology, Munich, Germany
10:10 – 10:30 Use of pre-hospital ethanol administration to improve outcome in methanol mass poisoning outbreaks: the Czech experience.
Sergey Zakharov, General University Hospital, Charles University, Prague, Czech Republic
At the end of this session the audience should be able to:
•Describe promising approaches, e.g. enhanced elimination of poison or modulation
of nicotinic receptors, which are under investigation in order to close existing gaps
in the treatment of patients with nerve agent poisoning in mass casualty scenarios
•Describe the effects of pre-hospital ethanol administration on patients with
suspected methanol poisoning during mass poisoning outbreaks on survival and
prevalence of long-term health sequelae
10:30 – 11:10
Coffee and electronic posters
Session chair: Richard Dart, Carlo Locatelli
11:10 – 11:30 Optimising the use of DMSA/succimer in lead poisoning
Sally Bradberry, National Poisons Information Service (Birmingham Unit), Birmingham, UK
11:30 – 11:50 Challenges in methylene blue therapy
Robert Hoffman, NYU School of Medicine, New York, USA
At the end of this session the audience should be able to:
•Rationalize the optimal use of DMSA/succimer in the treatment of lead poisoning
•Use methylene blue in patients with significant methemoglobinemia and suspected
G6PD deficiency
11:50 – 12:05
12:20 – 12:30
Acute digoxin overdose and response to antibody (DORA study) (abstract no. 18)
Betty SH Chan (1), Angela L Chiew (1), Colin B Page (2), Margaret O’Leary (3), Geoffrey K Isbister (3),
Nicholas A Buckley (4)
(1)
Prince of Wales Hospital, Sydney, Australia; (2) Princess Alexandra Hospital, Brisbane, Australia;
(3)
Calvary Mater Hospital, Newcastle, Australia; (4) University of Sydney, Sydney, Australia
Prevention of lethal colchicine toxicity by colchicine-specific Fab treatment in a porcine model (abstract no. 19)
Michael Eddleston (1), Adrian Thompson (1), Nicolas Fabresse (2), Jean-Claude Alvarez (2), Alain Astier
(3)
, Rachael Gregson (1), Ibrahim Al Abdulla (4), Tim King (1), Eddie Clutton (1), Frederic J Baud (5)
(1)
University of Edinburgh, Edinburgh, UK; (2) Université Versailles Saint-Quentin, Garches,
France; (3) School of Medicine Paris 12, Paris, France; (4) Micropharm Ltd, Newcastle Emlyn, UK;
(5)
University Paris Diderot, Assistance Publique - Hopitaux de Paris, UMR 8257, Paris, France
General discussion
12:30 – 14:00
Lunch and posters
12:05 – 12:20 7
MAIN CONGRESS
Room Montreal, Wednesday 17 May 2017 (afternoon)
Controversies in Pesticide Toxicology including Pro/Con Debate
Session chair: Michael Eddleston, Allister Vale
14:00 – 14:20 Neonicotinoid insecticides - safe for humans?
Allister Vale, National Poisons Information Service (Birmingham Unit), Birmingham, UK
14:20 – 14:40 Do neurobehavioral changes occur in humans as long-lasting consequences of acute poisoning with organophosphorus insecticides?
Marcello Lotti, University of Padua, Padova, Italy
14:40 – 15:00 Pesticides and Parkinson's disease: is there a causal link?
Martin Wilks, Swiss Centre for Applied Human Toxicology, University of Basel, Switzerland
15:00 – 15:45 Debate: Is glyphosate a probable human carcinogen?
Chris Portier, Independent Consultant, Thun, Switzerland
Danièle Court Marques, European Food Safety Authority (EFSA), Parma, Italy
At the end of this session the audience should be able to:
• Describe the effects of neonicotinoid insecticide exposure in humans
• Recognize the clinical conditions that may lead to neurobehavioral changes following
exposure to organophosphorus insecticides, describe confounding variables that
may affect the results of tests and decide whether such changes are a cause of
poisoning or its consequence
• Evaluate the strengths and limitations of the epidemiological and mechanistic evidence
for a causal relationship between exposure to specific pesticides and Parkinson’s disease
• Discuss how human and animal data are used to evaluate the risks of cancer from
exposure to an environmental agent, such as glyphosate
• Debate the use of weight of evidence approaches in the assessment of the toxicity,
genotoxicity and carcinogenicity of chemicals in general, and pesticides in particular
15:45 – 16:15 8
Coffee and electronic posters
MAIN CONGRESS
Room Singapore, Wednesday 17 May 2017 (afternoon)
Antidotes: Something Old, Something New, Something Borrowed,
Something Blue (cont)
Session chair: Irma de Vries, Horst Thiermann
14:00 – 14:15 § Acute hypersensitivity reaction to Crotalidae polyvalent immune Fab (CroFab) initially presenting as galactose-alpha-1,3-galactose (alpha-gal) allergy (abstract no. 20)
Katlin Brill, Justin Rizer, Joshua King, Nathan P Charlton
University of Virginia, Charlottesville, US
Infant botulism in Italy: antidote treatment consideration from 8 years’ experience (abstract no. 21)
Davide Lonati (1), Bruna Auricchio (2), Sarah Vecchio (1), Valeria M Petrolini (1), Virgilio
Costanzo (3), Fabrizio Anniballi (2), Carlo A Locatelli (1)
(1)
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and
Experimental Lab, Toxicology Unit, Maugeri Clinical and Scientific Institutes IRCCS and
University of Pavia, Pavia, Italy; (2) National Reference Centre for Botulism (NRCB),
Department of Veterinary Public Health and Food Safety, National Institute of Health
(ISS), Rome, Italy; (3) Ministry of Health, National Health System, Rome, Italy
Vipera ammodytes bites treated with antivenoms Viperfav® and ViperaTAb® (abstract no. 22)
Miran Brvar (1), Tihana Kurtović (2), Damjan Grenc (1), Maja Lang Balija (2), Igor Krizaj (3), Beata Halassy (2)
(1)
University Medical Centre Ljubljana, Ljubljana, Slovenia; (2) University of Zagreb,
Zagreb, Croatia; (3) Jožef Stefan Institute, Ljubljana, Slovenia
Discontinuation of N-acetylcysteine in patients meeting certain criteria: outcomes in a retrospective review (abstract no. 23)
Christopher Hoyte (1), Shireen Banerji (2)
(1)
University of Colorado School of Medicine, Aurora, US; (2) Rocky Mountain Poison and
Drug Center, Denver, US
Fewer adverse effects with a modified 2-bag intravenous acetylcysteine protocol compared
to the traditional 3-bag protocol in paracetamol overdose (abstract no. 24)
Richard McNulty (1), Elizabeth JM Lim (2), Pramodh Chandru (1), Naren Gunja (1)
(1)
Western Sydney Toxicology Service, Sydney, Australia; (2) Sydney University, Sydney, Australia
Palatability of tablets and capsule forms of N-acetylcysteine and methionine and associated adverse events in healthy volunteers (abstract no. 25)
Vindya M Pathiraja (1), Indika B Gawarammana (2), Nicholas A Buckley (3), Fahim Mohamed
(3)
, Shaluka F Jayamanna (4), Nicholas Osborne (3), Andrew H Dawson (5)
(1)
South Asian Toxicology Research Collaboration, Faculty of Medicine, University of
Peradeniya, Sri Lanka; (2) Department of Medicine, Faculty of Medicine, University of
Peradeniya, Sri Lanka; (3) Department of Pharmacology, School of Medical Sciences,
University of Sydney, Australia; (4) Department of Medicine, University of Kelaniya,
Ragama, Sri Lanka; (5) Royal Prince Alfred Clinical School, University of Sydney, Australia
*Efficacy of isosorbide dinitrate as an antidote in cyanide poisoning in a swine model
(abstract no. 26)
Ophir Lavon (1), Arik Eisenkraft (2)
(1)
Carmel Medical Center, Haifa, Israel; (2) Faculty of Medicine, Hebrew University, Jerusalem, Israel
14:15 – 14:30
14:30 – 14:45
14:45 – 15:00
15:00 – 15:15
15:15 – 15:30
15:30 – 15:45
15:45 – 16:15 Coffee and electronic posters
§ Shortlisted for Taylor & Francis best case study award
* Shortlisted for Taylor & Francis best scientific presentation award
9
MAIN CONGRESS
Room Montreal, Wednesday 17 May 2017 (afternoon)
Oral Session: Epidemiology of Poisoning
Session chair: John Thompson, Bill Banner
16:15 – 16:30 Dramatic improvement of poisoned patient survival in Southern province, Sri Lanka
(abstract no. 31)
Ishari S Fernando (1), Kasun M Fernando (2), Arosha Dissanayaka (3), Rohan Ruwanpura (1)
(1)
Teaching Hospital Karapitiya, Ambalangoda, Sri Lanka; (2) Base Hospital Balapitiya,
Ambalangoda, Sri Lanka; (3) University of Ruhuna, Galle, Sri Lanka
Patients with acute chemical exposure seen in Emergency Departments (ED) in Spain: results of the Spanish Toxic Surveillance System (STSS) 2015 (abstract no. 32)
Ana Ferrer Dufol (1), Santiago Nogue Xarau (2), Francisco Ruiz Ruiz (1), Clara Serrano
Ferrer (3), Agustin Garcia Urdangarin (4), Collaborators of the STSS (5)
(1)
Clinical University Hospital, Zaragoza, Spain; (2) Clinic Hospital, Barcelona, Spain;
(3)
Medical School, Zaragoza, Spain; (4) University Documentation Service, Zaragoza,
Spain; (5) FETOC, Zaragoza, Spain
Increases in pediatric vitamin D exposure calls to the US National Poison Data System
(abstract no. 33)
Marissa Hoffman (1), Jeanette Trella (2), Kevin C Osterhoudt (2)
(1)
The Children’s Hospital of Philadelphia, Philadelphia, US; (2) The Poison Control
Center at The Children’s Hospital of Philadelphia, Philadelphia, US
16:30 – 16:45 16:45 – 17:00 10
MAIN CONGRESS
Room Singapore, Wednesday 17 May 2017 (afternoon)
Oral Session: Poisoning Outbreaks
Session chair: Joanna Tempowski, Sergey Zakharov
16:15 – 16:30 *Elimination half-life and chronic health impairment 50 years after 2, 3, 7, 8-tetra
chloro-dibenzo- p- Dioxin (TCDD) exposure (abstract no. 34)
Daniela Pelclova (1), Zdenka Fenclova (1), Stepanka Vlckova (1), Pavel Urban (1), Petr Ridzon
(1)
, Tomas Navratil (2), Sergey Zakharov (1)
(1)
First Medical Faculty, Charles University, Prague, Czech Republic; (2) H. Heyrovsky
Institute of Physical Chemistry CAS v.v. i., Prague, Czech Republic
*National vitamin D intoxication outbreak among infants due to a manufacturing error
of vitamin D droplets: challenges for the health care system (abstract no. 35)
Søren Bøgevig (1), Lotte CG Hoegberg (2), Anders J Schou (3), Ida M Schmidt (4), Fie J Vojdeman
(5)
, Konstantinos Kamperis (6), Christian Mølgaard (7), Christine Brot (8), Henrik Christesen (3)
(1)
Department of Clinical Pharmacology, The Danish Poisons Information Center,
Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark; (2) Department
of Anaesthesiology, The Danish Poisons Information Center, Copenhagen University
Hospital Bispebjerg, Copenhagen, Denmark; (3) Hans Christian Andersen Children’s
Hospital, Odense University Hospital, Odense, Denmark; (4) Department of Paediatrics
and Adolescent Medicine, Copenhagen University Hospital Rigshospitalet, Copenhagen,
Denmark; (5) Department of Clinical Biochemistry, Copenhagen University Hospital
Bispebjerg, Copenhagen, Denmark; (6) Department of Paediatrics, Aarhus University
Hospital Skejby, Aarhus, Denmark; (7) Department of Nutrition, Exercise and Sports,
University of Copenhagen, Copenhagen, Denmark; (8) Danish Health Authority,
Copenhagen, Denmark
Dosage regimen of biperiden to treat haloperidol-induced severe facio-troncular dystonic
syndrome in children (abstract no. 36)
Frederic J Baud, Nicolas Peyraud, Micaela Serafini, Annette Heinzelmann
Médecins Sans Frontières, Paris, France
16:30 – 16:45 16:45 – 17:00 * Shortlisted for Taylor & Francis best scientific presentation award
11
MAIN CONGRESS
Room Montreal, Thursday 18 May 2017 (morning)
Louis Roche Lecture followed by
Pro/Con Debate & Paracetamol Poisoning: New Insights
Session chair: Bruno Mégarbane
08:45 – 09:00 09:00 – 09:45 Introduction and presentation of Louise Roche lecturer
New psychoactive substances: a challenge and impulse for clinical toxicology
Carlo Locatelli, Poison Control Centre, IRCCS Maugeri Foundation Hospital, Pavia, Italy
At the end of this lecture the audience should be able to:
• Reflect on the role of poisons centers/clinical toxicologists in the dissemination of
knowledge on novel psychoactive substance (NPS) toxicity and preventive activities
Session chair: Sally Bradberry, Patricia Casey
09:45 – 10:30 Debate: Shorter course IV acetylcysteine for paracetamol poisoning – it’s time to make a SNAP decision
James Dear, University of Edinburgh, UK
Richard C Dart, Rocky Mountain Poison and Drug Center, Denver Health and Hospital Authority, Denver, USA
At the end of this debate the audience should be able to:
• Explain the benefits of using novel shorter acetylcysteine (NAC) regimens with
regard to safety and speed of treatment
• Recognize the risks of premature termination of acetylcysteine treatment and how
to avoid them
10:30 – 11:10 Coffee and electronic posters
Session chair: Paul Dargan, D Nicholas Bateman
11:10 – 11:30 Biomarkers for paracetamol poisoning - research tools or practical aids to the management of the poisoned patient?
Nicholas A Buckley, University of Sydney, Australia
At the end of this lecture the audience should be able to:
• Identify which of the new paracetamol biomarkers are (and are not) relevant to their
clinical or research work
11:30 – 11:45 *Modified release paracetamol overdose: a prospective observational study (abstract no. 111)
Angela L Chiew (1), Geoffrey K Isbister (2), Colin B Page (3), Betty SH Chan (1), Nicholas A
Buckley (4)
(1)
Prince of Wales Hospital, Randwick, Australia; (2) University of Newcastle, Newcastle,
Australia; (3) Princess Alexandra Hospital, Brisbane, Australia; (4) The Children’s Hospital,
Westmead, Australia
* Shortlisted for Taylor & Francis best scientific presentation award
12
MAIN CONGRESS
Room Montreal, Thursday 18 May 2017 (morning)
Paracetamol Poisoning: New Insights (cont)
11:45 – 12:00 12:00 – 12:15 12:15 – 12:30 12:30 – 14:00 Analysis of an abbreviated acetylcysteine infusion protocol for repeated supratherapeutic ingestion (RSTI) of paracetamol (abstract no. 112)
Anselm Wong (1), Richard McNulty (2), Naren Gunja (2), Andis Graudins (3)
(1)
Austin Health, Victoria, Australia; (2) Westmead Hospital, Sydney, Australia; (3) Monash
Health, Victoria, Australia
Review of the availability of paracetamol sold as over-the-counter drugs in European
pharmacies; a descriptive cross sectional study (abstract no. 113)
Britt Morthorst (1), Annette Erlangsen (2), Merete Nordentoft (1), Keith Hawton (3), Lotte
CG Hoegberg (4), Kim P Dalhoff (4)
(1)
Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen,
Denmark; (2) Danish Research Institute for Suicide Prevention, Copenhagen, Denmark;
(3)
Centre for Suicide Research, Oxford University, Oxford, UK; (4) Bispebjerg and
Frederiksberg University Hospital, Copenhagen, Denmark
Evaluation of a US Food and Drug Administration mandate to limit acetaminophen in
prescription combination products (abstract no. 114)
David Goldberger, David Vearrier
Drexel University College of Medicine, Philadelphia, US
Lunch and posters
13
MAIN CONGRESS
Room Singapore, Thursday 18 May 2017 (morning)
Toxicology of Anti-Convulsant Drugs
Followed by Short Orals (2)
Session chair: Herbert Desel, Alison Good
09:50 – 10:10 Mitochondrial toxicity of antiepileptic drugs and implications for the treatment of mitochondrial epilepsy
Josef Finsterer, Municipality of Vienna, Austria
10:10 – 10:30 Are new anticonvulsant drugs safer than old ones?
Bruno Mégarbane, Paris-Diderot University, Paris, France
At the end of this session the audience should be able to:
• Assess which antiepileptic drugs (AEDs) are the most appropriate in patients with
mitochondrial disorders and epilepsy
• Summarize the mechanisms of action and potential toxicity of the new anticonvulsant
drugs
10:30 – 11:10 Coffee and electronic posters
Session chair: Mark Zammit, Kim Dalhoff
11:10 – 11:30 11:30 – 11:50 How to manage poisoning with anticonvulsants
Florian Eyer, Klinikum rechts der Isar, Technical University of Munich, Germany
Too much of a good thing: Antiepileptic toxicity
Sophie Gosselin, McGill University Health Centre, Montréal, Canada
At the end of this session the audience should be able to:
• Recognize that numerous anticonvulsants with different mechanisms of action exist,
resulting in distinct clinical symptoms of overdose
• Recognize the clinical presentation of antiepileptic toxicity and the role for
extracorporeal therapies
11:50
11:55
14
A characterization of levetiracetam abuse and misuse reported to US Poison Centers through the National Poison Data System (NPDS) (abstract no. 115)
Christopher Hoyte (1,2), Shireen Banerji (2)
(1)
University of Colorado School of Medicine, Aurora, US; (2) Rocky Mountain Poison
and Drug Center, Denver, US
Acute lamotrigine overdoses treated at the department of Emergency and Clinical Toxicology during a 3-year period clinical overview (abstract no. 116)
Gordana Vuković-Ercegović (1), Nataša Perković-Vukčević (1), Olivera Potrebić (1), Vesna
Mijatovic (2), Jasmina Jović-Stošič (1)
(1)
Military Medical Academy, Belgrade, Serbia; (2) Faculty of Medicine, University of
Novi Sad, Novi Sad, Serbia
MAIN CONGRESS
Room Singapore, Thursday 18 May 2017 (morning)
Short Orals (2) (cont)
12:00
Clinical features of acute carbamazepine poisoning in children: a 5-year retrospective study (abstract no. 117)
Viorela Nitescu, Dora Boghitoiu, Iolanda C Vivisenco, Alexandru Ulmeanu, Coriolan
E Ulmeanu
Pediatric Poisoning Centre, Emergency Clinical Hospital for Children “Grigore
Alexandrescu”, Bucharest, Romania
12:05
Severe toxicity following lamotrigine overdose: a review of calls to Australia’s largest Poisons Information Centre (abstract no. 118)
Rose Cairns (1), Andrew H Dawson (1), Darren M Roberts (2), Nicholas A Buckley (1)
(1)
The New South Wales Poisons Information Centre, The Children’s Hospital at
Westmead; Sydney Medical School, The University of Sydney, Sydney, Australia; (2) The
New South Wales Poisons Information Centre, The Children’s Hospital at Westmead;
Renal Medicine Unit, Canberra Hospital, Canberra, Australia
12:10
Severe valproic acid poisoning associated with atrial fibrillation and extreme high serum concentrations (abstract no. 119)
Csaba Pap, Péterfy Hospital, Budapest, Hungary
12:15
Lamotrigine enquiries to the Austrian Poisons Information Centre: a retrospective 14 year study (abstract no. 120)
Kinga Bartecka-Mino, Helmut Schiel, Tara Arif
Poisons Information Centre, Vienna, Austria
12:20 Exposures to valproic acid: a 14 year descriptive study of Austrian Poisons Information Centre data (abstract no. 121)
Tara Arif, Kinga Bartecka-Mino, Helmut Schiel
Poisons Information Centre, Vienna, Austria
12:25 – 12:30 General discussion
12:30 – 14:00 Lunch and posters
15
MAIN CONGRESS
Room Montreal, Thursday 18 May 2017 (afternoon)
The Virtual Toxicologist: Leveraging Social Media for Toxicology
Education, Outreach & Research followed by Short Oral
Presentations Social Media
Session chair: Peter Chai, Davide Lonati
13:55 – 14:00
Introduction to the Mini Symposium/Introduction to Social Media Platforms
Peter R Chai, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA
14:00 – 14:15 Social media in toxicologic disasters
Timothy B Erickson, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA
14:15 – 14:30 Social Media for online education
Anselm Wong, Austin Health, Melbourne, Australia
14:30 – 14:45 Twitter and Facebook groups: How we can maximize our toxicology education and
engage learners
Matthew Griswold, University of Massachusetts Medical School, Worcester, USA
Mark Neavyn, University of Massachusetts Medical School, Worcester, USA
14:45 – 15:00 The National Poisons Information Centre experience in social media for outreach
Niamh English, National Poisons Information Centre Ireland, Dublin, Ireland
15:00 – 15:15 The Edinburgh Clinical Toxicology experience in social media
Euan Sandilands, National Poisons Information Centre Edinburgh, Edinburgh, UK
15:15 – 15:30 Research in drug trends, substances of abuse and self-harm on social media
Edward W Boyer, Harvard Medical School, Boston, USA
Alex Manini, Icahn School of Medicine at Mount Sinai, New York, USA
At the end of this mini symposium the audience should be able to:
• Summarize how to use various social media platforms for toxicologists
• Recognize components of Tweets that maximize impact among students of toxicology,
and describe common ethical dilemmas encountered by toxicologists using social
media platforms
• Describe methods used to discover social media trends in intentional drug overdose
and novel drugs of abuse
15:30 15:35
15:40 15:45 – 16:15 16
Please “like” us: Facebook as an outreach tool for a poisons information centre
(abstract no. 129)
Niamh Walsh, Patricia Casey, Edel Duggan
NPIC Ireland, Dublin, Ireland
Linguistic differences between Spanish and English tweets that mention opioids
(abstract no. 130)
Michael Chary (1), Alex F Manini (2)
(1)
New York Presbyterian Queens, Peekskil, US; (2) Elmhurst Hospital Center, Elmhurst, US
YouTube™ is a feasible tool to disseminate educational toxicology videoconferences:
The Global Educational Toxicology Uniting Project (GETUP) (abstract no. 131)
Anselm Wong (1), Rais Vohra (2), Anne Creaton (3), Zeff Koutsogiannis (1), Shaun L Greene (1)
(1)
Austin Health, Victoria, Australia; (2) Fresno Medical Center, California, US; (3) Colonial
War Memorial Hospital, Suva, Fiji
Coffee and electronic posters
MAIN CONGRESS
Room Singapore, Thursday 18 May 2017 (afternoon)
Experimental and Applied Research
Toxicosurveillance (including Poison Centre Activities)
Session chair: Florian Eyer, Sophie Gosselin
14:00 Comparative extractive efficiency of continuous veno-venous hemodiafiltration (CVVHDF) and molecular adsorbent recirculating system (MARS) in simulated verapamil
poisoning: an ex vivo study (abstract no. 122)
Nicolas Caill (1), Frederic J Baud (2), Romain Jouffroy (2), Jean-Claude Alvarez (3), Lionel Lamhaut (4)
(1)
Assistance Publique-Hopitaux de Paris, Paris, France; (2) Assistance PubliqueHopitaux de Paris; University Paris Diderot, Paris, France; (3) AP-HP; University VSQ,
Paris, France; (4) AP-HP; University Paris Descartes, Paris, France
Leukotriene-mediated neuroinflammation and toxic brain damage in methanol
poisoning (abstract no. 123)
Sergey Zakharov (1), Katerina Kotikova (2), Olga Nurieva (2), Petr Kacer (3), Tomas Navratil
(4)
, Daniela Pelclova (2)
(1)
First Faculty of Medicine, Charles University, Department of Occupational Medicine;
Toxicological Information Centre, General University Hospital, Prague, Czech Republic; (2)
First Faculty of Medicine, Charles University, Department of Occupational Medicine, Prague,
Czech Republic; (3) Institute of Chemical Technology, Prague, Czech Republic; (4) Department of
Biomimetic Electrochemistry, J. Heyrovský Institute of Physical Chemistry of the AS CR, v.v.i,
Prague, Czech Republic
Transient receptor potential (TRP) channels as therapeutic targets in toxic lung injury
(abstract no. 124)
Dirk Steinritz (1), Thomas Gudermann (2), Tanja Popp (1), Alexander Dietrich (2), Bernhard
Stenger (2), Horst Thiermann (1)
(1)
Bundeswehr Institute of Pharmacology and Toxicology, Munich, Germany; (2)
Walther-Straub-Institute of Pharmacology and Toxicology, Ludwig-MaximilianUniversity Munich, Munich, Germany
Pharmacogenetics of 3,4-methylenedioxymethamphetamine (MDMA): cytochrome
P450 polymorphisms moderate pharmacokinetics and pharmacodynamic effects of
MDMA in healthy subjects (abstract no. 125)
Patrick Vizeli, Yasmin Schmid, Matthias E Liechti
Universitätsspital Basel, Basel, Switzerland
Age of misuse exposures reported by the Global Toxicosurveillance Network (GTNet)
(abstract no. 126)
Laura J Fischer (1), Zachary R Margolin (1), Jody L Green (1), Bruno Mégarbane (2), Antoine
Villa (2), Andreas Schaper (3), Martin Ebbecke (3), Fabrizio Sesana (4), Simon HL Thomas (5),
John P Thompson (6)
(1)
Rocky Mountain Poison & Drug Center, Denver Health, Denver, US; (2) Centre
Antipoison et de Toxicovigilance de Paris, Paris, France; (3) GIZ-Nord Poisons Centre,
University Medical Center, Göttingen, Germany; (4) Poison Control Centre of Milan,
Milan, Italy; (5) National Poisons Information Service, Newcastle, UK; (6) National
Poisons Information Service, Cardiff, UK
14:15 14:30 14:45 15:00 17
MAIN CONGRESS
Room Singapore, Thursday 18 May 2017 (afternoon)
Toxicosurveillance (including Poison Centre Activities) (cont)
15:15 15:30 *Using Swedish Poisons Information Centre data to identify chemical accident hazards
at the workplace (abstract no. 127)
Anita Annas (1), Karin Feychting (1), Mattias Öberg (2), Linda Schenk (2)
(1)
Swedish Poisons Information Centre, Stockholm, Sweden; (2) Institute of Environmental
Medicine, Stockholm, Sweden
Utilisation of desferrioxamine in iron poisoning: experience of the UK National Poisons
Information Service (NPIS) 2014-2016 (abstract no. 128)
Victoria A Eagling (1), Euan A Sandilands (1), Leonard C Hawkins (2), Gillian A Cooper (3), Ted T
Cheung (4), Simon HL Thomas (2), John P Thompson (3), J Allister Vale (4), Michael Eddleston
(5)
, D Nicholas Bateman (6)
(1)
Royal Infirmary of Edinburgh, Edinburgh, UK; (2) Regional Drug and Therapeutics
Centre, Newcastle, UK; (3) University Hospital Llandough, Cardiff, UK; (4) City Hospital,
Birmingham, UK; (5) Royal Infirmary of Edinburgh / University of Edinburgh, Edinburgh,
UK; (6) University of Edinburgh, Edinburgh, UK
15:45 – 16:15 Coffee and electronic posters
* Shortlisted for Taylor & Francis best scientific presentation award
18
MAIN CONGRESS
Room Montreal, Thursday 18 May 2017 (afternoon)
The Virtual Toxicologist: Leveraging Social Media for Toxicology
Education, Outreach & Research (cont)
Session chair: Hugo Kupferschmidt, Peter Hultén
16:15 – 16:45 Round Table on Social Media
Mark Neavyn, UMass Memorial Center, Worcester, USA (moderator)
Katharine Boyle, Beth Israel Deaconess Medical Center, Boston, USA
Peter R Chai, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA
Niamh English, National Poisons Information Centre Ireland, Dublin, Ireland
Timothy Erickson, Brigham and Women’s Hospital, Boston, USA
Euan Sandilands, National Poisons Information Centre Edinburgh, UK
17:00 – 18:30 EAPCCT General Assembly
Room Singapore, Thursday 18 May 2017 (afternoon)
Novel Psychoactive Substances
Session chair: Edward Krenzelok, David Wood
16:15 – 16:30 *Toxicity associated with the use of α-PVP (α-pyrrolidinovalerophenone): a case series of
417 patients presenting to a regional poisons treatment centre (abstract no. 136)
Konstantin Brusin (1), Yulia V Kraeva (2), Maria A Gofenberg (2), David M Wood (3), Paul I Dargan (4)
(1)
Kaplan Medical Centre, Rehovot, Israel; (2) Sverdlovsk Regional Psychiatric Hospital,
Yekaterinburg, Russian Federation; (3) Guy’s and St Thomas NHS Foundation Trust, London,
UK; (4) Guy’s and St Thomas’ NHS Foundation Trust and King’s Health Partners, London, UK
§ Severe cardiovascular toxicity, cerebral hemorrhage and mortality after using 4-fluoroamphetamine (4-FA) (abstract no. 137) Johanna J Nugteren-Van Lonkhuyzen, Antoinette JHP Van Riel, Irma de Vries, Saskia J
Rietjens, Laura Hondebrink
University Medical Center Utrecht (UMCU), Utrecht, The Netherlands
*Rhabdomyolysis induced by psychoactive substances: an analysis of EuroDEN data
(abstract no. 138)
Wojciech Waldman (1), Jacek Sein Anand (1), Piotr M Kabata (2), Alison M Dines (3), David M
Wood (3), Christopher Yates (4), Fridtjof Heyerdahl (5), Knut Erik Hovda (5), Isabelle Giraudon
(6)
, On behalf of Euro- DEN Research Group (7), Paul I Dargan (3)
(1)
Medical University of Gdansk, Gdańsk, Poland; (2) Pomeranian Centre of Toxicology,
Gdańsk, Poland; (3) Guy’s and St Thomas’ NHS Foundation Trust and King’s Health
Partners, London, UK; (4) Hospital Universitari Son Espases, Mallorca, Spain; (5) Medical
Division, Oslo University Hospital, Oslo, Norway; (6) European Monitoring Centre for
Drugs and Drug Addiction (EMCDDA), Lisbon, Portugal; (7) Euro-DEN Research Group
16:30 – 16:45 16:45 – 17:00 § Shortlisted for Taylor & Francis best case study award
* Shortlisted for Taylor & Francis best scientific presentation award
19
MAIN CONGRESS
Room Montreal, Friday 19 May 2017 (morning)
Young Investigator Award (YIA)
Session chair: Robert Palmer, Simon Thomas
08:45 – 08:50 08:50 – 09:05 Introduction
Mechanistic biomarkers stratify patients after paracetamol overdose with high
sensitivity and specificity (abstract no. 220)
James W Dear (1), Joanna I Clarke (2), Ben Francis (2), Lowri Philips (1), Jonathan Wraight
(1)
, Paul I Dargan (3), David M Wood (3), Jamie Cooper (4), Simon HL Thomas (5), Andrea
Jorgensen (2), Munir Pirmohamed (2), B. Kevin Park (2), Daniel J Antoine (2)
(1)
University of Edinburgh, Edinburgh, UK; (2) University of Liverpool, Liverpool, UK; (3)
Guy’s and St Thomas’ NHS Foundation Trust, London, UK; (4) Aberdeen Royal Infirmary,
Aberdeen, UK; (5) Newcastle University, Newcastle, UK
Ciguatoxin-induced chronic disease unmasks people carrying human leukocyte
antigen (HLA) epitopes peculiar to celiac disease and rheumatoid arthritis (abstract no. 221)
Azzurra Schicchi (1), Annamaria Pasi (2), Davide Lonati (1), Teresa Coccini (1), Carlo A Locatelli (1),
Miriam Martinetti (2)
(1)
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and
Experimental Lab, Toxicology Unit, Maugeri Clinical and Scientific Institutes IRCCS
and University of Pavia, Pavia, Italy; (2) Department of Hematology, IRCCS Policlinico S.
Matteo Foundation, University of Pavia, Pavia, Italy
Imaging drug-drug interaction using positron emission tomography (PET) scans:
investigating the impact of diazepam on buprenorphine-induced respiratory
depression (abstract no. 222)
Nicolas Tournier (1), Dominique Vodovar (2), Géraldine Pottier (1), Sylvain Auvity (1), Bruno
Mégarbane (3), Irène Buvat (1), Fabien Caillé (1)
(1)
IMIV, CEA, Inserm, CNRS, Paris-Sud & Paris-Saclay Universities, Orsay, France; (2) INSERM
UMRS-1144, Paris-Descartes & Paris-Diderot Universities, Paris, France; (3) Department
of Medical and Toxicological Critical Care, Lariboisière Hospital, Paris, France
Utility of QT interval corrected by the Rautaharju method to predict drug-induced
torsades de pointes (abstract no. 223)
Rittirak Othong (1), Suttisak Wattanasansomboon (1), Thanakorn Kruutsaha (1), Douglas
Chesson (2), Ziad Kazzi (2)
(1)
Vajira Hospital, Bangkok, Thailand; (2) Emory University, Atlanta, US
Judging commences
Lucy in the Sky with Diamonds or LSD: Past, Present and Future
Matthias Liechti, University Hospital Basel, Switzerland
Paracelsus in Basel
Martin Wilks, Swiss Centre for Applied Human Toxicology, University of Basel, Switzerland
09:05 – 09:20
09:20 – 09:35
09:35 – 09:50 09:50
09:50 – 10:05 10:05 – 10:20 At this end of these lectures the audience should be able to:
• Describe the role of Basel in the detection and past and present research on LSD
• Discuss Paracelsus’ time as city physician in Basel in 1527/28 and his approach to the
use of ‘poisons’ as therapeutics
10:20 – 10:30 Presentation to the winner of the YIA
10:30 – 11:10 Coffee and electronic posters
20
MAIN CONGRESS
Room Montreal, Friday 19 May 2017 (morning)
Biomarkers, Clinical Toxicology and Translational Medicine (APAMT
Symposium at EAPCCT)
Session chair: 11:10 – 11:30
11:30 – 11:50
11:50 – 12:10
12:10 – 12:30
Jou-Fang Deng, Charles McKay
Regulatory toxicology: are biomarkers the missing link?
Darren Roberts, St Vincent's Hospital, Sydney, Australia and Medical School,
Australian National University, Canberra, Australia
Use of biomarkers in laboratory-models of toxicity
Klintean Wunnapuk, Chiang Mai University, Chiang Mai, Thailand
Biomarkers of kidney injury: clinical research generates both questions and answers
Fahim Mohammed, SACTRC, University of Peradeniya, Sri Lanka
Biomarkers in snake envenomation: local data prompts broad applications
Anjana Silva, Monash Venom Group, Monash University, Clayton, Australia and Rajarata
University of Sri Lanka, Saliyapura, Sri Lanka
At the end of this session the audience should be able to:
• Describe the limitations of existing criteria used by regulatory agencies and
opportunities for newer approaches based on biomarkers
• Explain how to use pre-clinical animal models in pesticide toxicology research and
how they relate to clinical practice
• Summarize examples of the variability in currently used biomarkers on the apparent
severity of nephrotoxicity following poisoning
• Describe the relevance of different biomarkers of snake envenoming to the clinical
management of the patient
12:30 – 14:00
Lunch and posters
21
MAIN CONGRESS
Room Singapore, Friday 19 May 2017 (morning)
Short Orals (3)
Session chair: Nicolas Buckley, Thomas Zilker
11:10 QT prolongation in opioid poisoning is mostly due to methadone (abstract no. 230)
Gopi Mann (1), Naren Gunja (2)
(1)
NSW Poisons Information Centre, Sydney, Australia; (2) Discipline of Emergency
Medicine, Sydney Medical School, Sydney, Australia
Comparison of self-reported recreational substance use with immunoassay and liquid
chromatography mass spectrometry findings in cases with acute recreational drug
toxicity (abstract no. 231)
Evangelia Liakoni, Patrick C Dolder, Katharina M Rentsch, Matthias E Liechti
University Hospital Basel and University of Basel, Basel, Switzerland
Prognostic utility of initial lactate for Emergency Department (ED) drug overdose
fatality: a validation cohort (abstract no. 232)
Randy Cheung (1), Robert S Hoffman (2), David Vlahov (3), Alex F Manini (4)
(1)
State University of New York, Buffalo, US; (2) NYU School of Medicine, New York, US;
(3)
University of California at San Francisco, San Francisco, US; (4) The Icahn School of
Medicine at Mount Sinai, New York, US
Does targeted temperature management improve hospital survival for presumed drug
overdose-related cardiac arrest? (abstract no. 233)
Sharaf Khan (1), Chad Meyers (2), Suzanne Bentley (2), Yanoh Jalloh (1), Alex F Manini (2)
(1)
The Icahn School of Medicine at Mount Sinai, New York, US; (2) The Icahn School of
Medicine at Mount Sinai, Elmhurst Hospital Center, New York, US
Pharmacokinetics and pharmacodynamics of two doses of oral LSD in healthy subjects
(abstract no. 234)
Matthias E Liechti, Yasmin Schmid, Katharina M Rentsch, Felix Hammann, Patrick C Dolder
University Hospital Basel, Basel, Switzerland
Relationship between poison center opioid exposure data and mortality rates and
National Vital Statistics System mortality rates (abstract no. 235)
Janetta L Iwanicki, Zachary R Margolin, Stevan G Severtson, Richard C Dart
Rocky Mountain Poison and Drug Center, Denver, US
Tramadol poisoning in the intensive care unit: clinical presentation and prognostic
value of plasma tramadol concentration on admission (abstract no. 236)
Christophe Camillerapp (1), Laurence Labat (2), Marion Soichot (3), Isabelle Malissin (1),
Pierre Garçon (1), Antoine Goury (1), Lamia Kerdjana (1), Sébastian Voicu (1), Nicolas Deye (1),
Bruno Mégarbane (1)
(1)
Department of Medical and Toxicological Critical Care, Lariboisière Hospital, Paris,
France; (2) Laboratory of Toxicology, Cochin Hospital, Paris, France; (3) Laboratory of
Toxicology, Lariboisière Hospital, Paris, France
Pack size restriction of mild analgesics sold as over-the-counter drugs in pharmacies in
Denmark: preliminary register findings (abstract no. 237)
Britt Morthorst (1), Annette Erlangsen (2), Keith Hawton (3), Kim P Dalhoff (4), Merete
Nordentoft (1)
(1)
Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen,
Denmark; (2) Danish Research Institute for Suicide Prevention, Copenhagen, Denmark;
(3)
Centre for Suicide Research, Oxford University, Oxford, UK; (4) Bispebjerg and
Frederiksberg University Hospital, Copenhagen
11:15 11:20 11:25 11:30 11:35 11:40 11:45 22
MAIN CONGRESS
Room Singapore, Friday 19 May 2017 (morning)
Short Orals (3) (cont) & Education and Outreach
11:50 Seasonality in intentional drug intake by adolescents (abstract no. 238)
Arjen Koppen, Claudine C Hunault, Irma de Vries
Dutch Poison Information Center, Utrecht, The Netherlands
11:55 Caustic ingestion in children: experience of a Pediatric Emergency Department in
Rome (abstract no. 239)
Marco Marano, Francesco P Rossi, Antonino Reale, Mara Pisani, Corrado Cecchetti,
Matteo Di Nardo, Valentina A Ferro, Umberto Raucci, Daniela Perrotta, Luigi Dall’Oglio,
Filippo Torroni, Paola De Angelis, Tamara Caldaro, Leonardo Genuini, Nicola Pirozzi
Ospedale Pediatrico Bambino Gesù, Rome, Italy
12:00 Drug-facilitated crimes (DFC): four years of admission in a French emergency medico
legal center specializing in victims of assaults (abstract no. 240)
Emilie Christin (1), Cecile Richeton (1), Régis Bédry (1), Nathalie Grosleron (1), Jean Hiquet (1),
Véronique Dumestre-Toulet (2), Sophie Gromb-Monnoyeur (1)
(1)
University Hospital Pellegrin, Bordeaux, France; (2) TOXGEN Lab, Bordeaux, France
12:05 Severe poisonings and their outcomes reported to the National Poisons Information
Service (NPIS), 2008-2015 (abstract no. 241)
Stephen SD Jones (1), John P Thompson (1), Sally M Bradberry (2), Euan A Sandilands (3),
Simon HL Thomas (4)
(1)
UK National Poisons Information Service, Cardiff, UK; (2) UK National Poisons
Information Service, Birmingham, UK; (3) UK National Poisons Information Service,
Edinburgh, UK; (4) UK National Poisons Information Service, Newcastle, UK
12:10 Emergency Department presentations with illicit drugs associated with problematic
drug use (iPDU) toxicity are not commonly associated with co-use of new psychoactive
substances (NPS) (abstract no. 242) Luke C De La Rue (1), David M Wood (1), Alison M Dines (1), Knut Erik Hovda (2), Fridtjof
Heyerdahl (2), Christopher Yates (3), Isabelle Giraudon (4), Paul I Dargan (1), Euro-DEN Plus
Research Group (1)
(1)
Guy’s and St Thomas’ NHS Foundation Trust and King’s Health Partners, London, UK;
(2)
Oslo University Hospital, Oslo, Norway; (3) Hospital Universitari Son Espases, Mallorca,
Spain; (4) European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), Lisbon,
Portugal
12:15-12:30 Impact of online toxicology training on health professionals: the Global Educational
oxicology Uniting Project (GETUP) (abstract no. 243)
Anselm Wong (1), Andrew Stolbach (2), Andrew H Dawson (3), Rais Vohra (4)
(1)
Austin Health, Victoria, Australia; (2) Johns Hopkins University, Baltimore, US; (3) Royal
Prince Alfred Hospital, Sydney, Australia; (4) UCSF Fresno Medical Center, California, US
12:30–14:00
Lunch and posters
23
MAIN CONGRESS
Room Montreal, Friday 19 May 2017 (afternoon)
Pre-hospital Management of Poisonings
Session chair: 14:00 – 14:20
Miran Brvar, Dabor Résière
In the urban area of a developed country: the Oslo experience
Odd Martin Vallersnes, Oslo Accident and Emergency Outpatient Clinic, Oslo, Norway
14:20 – 14:40 In the rural area of a developing country: the Bangladesh experience
Fazle Rabbi Chowdhury, Nuffield Department of Medicine, University of Oxford, UK
14:40 – 15:00 On the way to hospital with the paramedics: the US experience
Alex Manini, The Icahn School of Medicine at Mount Sinai, New York, USA
15:00 – 15:20 On the scene by a physician-manned emergency medical service: the French SAMU experience
Vincent Danel, Centre Hospitalier Universitaire, Grenoble, France
15:20 – 15:40 With long-distance transport: the Australian experience
Shaun Greene, Victorian Poisons Information Centre, Austin Toxicology Service,
Melbourne, Australia
At the end of this session the audience should be able to:
• Describe a systematic procedure for the clinical assessment and management of
patients with acute recreational drug toxicity
• Identify the limitations remaining in developing countries in terms of pre-hospital
management of poisonings
• Describe prehospital management of poisoning in the US
• Summarize the organization of prehospital care in France and the complementary
roles of medical teams, fire brigades and private ambulances with reference to
specific treatments and antidotes that can be given on scene
• Describe the unique challenges and solutions of providing pre-hospital care to
poisoned patients in Australia
15:40 – 15:45 General discussion
15:45 – 16:15 Coffee and electronic posters
24
MAIN CONGRESS
Room Singapore, Friday 19 May 2017 (afternoon)
Education and Outreach (cont)
Best Paper Session
Special Session
Session chair: Régis Bédry, Geert Verstegen
14:00 – 14:20 Sliding drugs: a co-production by a Poison Centre and School of Cinema for preventing
NPS use by teenagers (abstract no. 244)
Carlo A Locatelli (1), Giulia Scaravaggi (1), Eleonora Buscaglia (1), Davide Lonati (1), Sarah Vecchio (1),
Valeria M Petrolini (1), Marta Crevani (1), Azzurra Schicchi (1), Mara Garbi (1), Germano Monetti (2),
Fabio Cottichelli (2), Diego Cassani (2)
(1)
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental
Lab, Toxicology Unit, Maugeri Clinical and Scientific Institutes IRCCS and University of Pavia, Pavia,
Italy; (2) Civic School of Cinema “Luchino Visconti” of Milan, Milan, Italy
14:20 – 15:20 Best Paper session
An international panel have each been asked to select a clinical toxicology paper
published in 2016 that they consider to be among the best. The aim is to highlight
papers that have changed or challenged clinical practice, taught something new or
unexpected, improved understanding of toxicological mechanisms, or inspired the
panellists. The speakers will defend their choice in a brief 10 minute presentation
followed by discussion.
Discussants:
Nicholas A Buckley
Plasma paracetamol concentration at hospital presentation has a dose-dependent
relationship with liver injury despite prompt treatment with intravenous acetylcysteine
David G. Cairney, Hannah K. S. Beckwith, Khalid Al-Hourani, Michael Eddleston, D.
Nicholas Bateman & James W. Dear
Clinical Toxicology (2016): 54:5, 405-410.
Robert Palmer
Interpretation of postmortem vitreous concentrations of sodium and chloride
B. Zilg, K. Alkass, S. Berg, H. Druid
Forensic Science International 2016: 263:107–113.
Mark Zammit
Healthcare professionals are less confident in managing acute toxicity related to the
use of new psychoactive substances (NPS) compared with classical recreational drugs.
Wood DM, Ceronie B, Dargan PI
QJM 2016: 109(8):527-9.
15:20 – 15:40 Special session
Polonium-210 poisoning: a first-hand account
Paul Dargan, Guy's and St Thomas' NHS Foundation Trust, London, UK
At the end of this lecture the audience should be able to:
• Summarize the lessons learnt from well-publicized case of polonium-210 poisoning
15:45 – 16:15
Coffee and electronic posters
25
MAIN CONGRESS
Room Montreal, Friday 19 May 2017 (afternoon)
Pre-hospital Management of Poisonings (cont)
Session chair: Nicola Bates, Frederic Baud
16:15 – 16:30 *Reductions in emergency department referrals from primary care after use of the UK
National Poisons Information Service (abstract no. 249)
Muhammad EMO Elamin (1), David A James (1), Peter Holmes (1), Gillian Jackson (2), John P
Thompson (3), Euan A Sandilands (2), Sally M Bradberry (4), Simon HL Thomas (1)
(1)
NPIS Newcastle, Regional Drug and Therapeutics Centre, Newcastle upon Tyne,
UK; (2) NPIS Edinburgh, Scottish Poisons Information Bureau, Edinburgh, UK; (3) NPIS
Cardiff, University Hospital Llandough, Cardiff, UK; (4) NPIS Birmingham, City Hospital,
Birmingham, UK
Venlafaxine poisoning in the intensive care unit: clinical presentation and role of the
cytochrome P450 2D6 phenotype in the onset of cardiovascular complications
(abstract no. 250)
David Ambroise (1), Marie-Anne Loriot (2), Isabelle Malissin (1), Lucie Chevillard (3), Marion
Soichot (4), Emmanuel Bourgogne (4), Bruno Mégarbane (1)
(1)
Department of Medical and Toxicological Critical Care, Lariboisière Hospital, Paris,
France; (2) Department of Biochemistry, HEGP, Paris, France; (3) INSERM UMRS-1144,
Paris-Descartes & Paris-Diderot Universities, Paris, France; (4) Laboratory of Toxicology,
Lariboisière Hospital, Paris, France
Baclofen poisoning in the intensive care unit: clinical features and investigation of the
relationships between toxic encephalopathy and the plasma baclofen concentration
(abstract no. 251)
Lucie Chevillard (1), Souaad Farah (2), Laurence Labat (3), Hélène Amiel-Nieman (2), Isabelle
Malissin (2), Nathalie Kubis (2), Xavier Declèves (3), Bruno Mégarbane (1-3)
(1)
INSERM UMRS-1144 Paris-Descartes University, Paris, France; (2) Lariboisière Hospital,
Paris, France; (3) Cochin Hospital, Paris, France
16:30 – 16:45 16:45 – 17:00 * Shortlisted for Taylor & Francis best scientific presentation award
26
MAIN CONGRESS
Room Singapore, Friday 19 May 2017 (afternoon)
Natural Toxins
Session chair: Andis Graudins, Emilio Salgado
16:15 – 16:30 Myanmar Snakebite Project: analysis of the first 627 prospective cases (abstract no. 252)
Julian White (1), Sam Alfred (2), Chen Au Peh (2), David Warrell (3), David Bates (1), Afzal
Mahmood (4), Myat Myat Thein (5), Su Synt Synt San (5), Khin Thida Thwin (6)
(1)
Women’s and Children’s Hospital, North Adelaide, Australia; (2) Royal Adelaide
Hospital, Adelaide, Australia; (3) University of Oxford, Oxford, UK; (4) University of
Adelaide, Adelaide, Australia; (5) Mandalay General Hospital, Mandalay, Myanmar; (6)
Yangon Specialist Hospital, Yangon, Myanmar
Mushroom poisonings in the Slovak Republic: a 20-year retrospective analysis
(abstract no. 253)
Silvia Plackova (1), Blazena Caganova (1), Olga Otrubova (1), Jaroslav Kresanek (2), Igor
Batora (1)
(1)
National Toxicological Information Centre, Department of Occupational Medicine and
Toxicology, University Hospital Bratislava and Faculty of Medicine Comenius University,
Bratislava, Slovakia; (2) Slovak Medical University, Bratislava, Slovakia
Molecular and toxicological study of Italian Viper venom neurotoxicity (abstract no. 254)
Marco Pirazzini (1), Giulia Zanetti (1), Cesare Montecucco (2), Carlo A Locatelli (3), Davide
Lonati (3), Ornella Rossetto (1)
(1)
Department of Biomedical Sciences, University of Padova, Padova, Italy; (2) National
Research Council Institute of Neuroscience, Padova, Italy; (3) Pavia Poison Control Center
- National Toxicology Information Centre, Toxicology Unit, Maugeri Clinical and Scientific
Institutes IRCCS and University of Pavia, Pavia, Italy
16:30 – 16:45 16:45 – 17:00 27
ELECTRONIC POSTERS
WEDNESDAY 17 MAY 2017 (morning)
10:30 – 11:10
Session chair: Davide Lonati
1. Deltamethrin poisoning in two children following treatment of head lice with a veterinary product
(abstract no. 1)
Galina N Bashinskaya (1), Yury N Ostapenko (2), Gulbanu S Sadykova (3), Saltanat T Tulegenova (3), Kuandyk A
Amrekulov (3)
(1)
Municipal Hospital No 1, Astana, Kazakhstan; (2) Research and Applied Toxicology Center of Federal Medical
and Biological Agency, Moscow, Russian Federation; (3) Municipal Pediatric Hospital, Taraz, Kazakhstan
2. Polyneuropathy following fenitrothion poisoning (abstract no. 2)
Kyoung Ho Choi
Uijeonbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
3. Deltamethrin acute poisoning by intravenous injection (abstract no. 3)
Isabel Sanjoaquín Conde (1), Laura Sanchez Blasco (2), Antonio Güemes Sanchez (2), Ana Ferrer Dufol (3)
(1)
Infectious Disease Service, Clinical University Hospital, Zaragoza, Spain; (2) Surgery Service, Clinical
University Hospital, Zaragoza, Spain; (3) Unit of Clinical Toxicology, Clinical University Hospital, Zaragoza, Spain
4. Toxicity indicator value of plasma pseudocholinesterase in hepatic patients (abstract no. 4)
Ahmed R Ragab Ali, Fawaz Al-Mousa
Toxicology Consultant, Riyadah, Saudi Arabia
5. Delayed and fatal toxicity of chlorfenapyr (abstract no. 6)
Chun-Chi Lin (1), Chen-Chang Yang (2)
(1)
National Yang-Ming University Hospital, I-Lan, Taiwan; (2) National Yang-Ming University, Taipei, Taiwan
WEDNESDAY 17 MAY 2017 (afternoon)
15:45 – 16:15
Session chair: Ana Ferrer Dufol
1. Risk factors for mortality after caustic ingestion (abstract no. 27)
Blažena Cagáňová (1), Silvia Plačková (1), Tatiana Foltánová (2), Katerina Plachá (1), Erik Puchoň (2), Elena
Ondriašová (2), Igor Batora (1)
(1)
National Toxicological Information Centre, Department of Occupational Medicine and Toxicology,
University Hospital Bratislava and Faculty of Medicine Comenius University, Bratislava, Slovakia; (2) Faculty of
Pharmacy, Comenius University, Bratislava, Slovakia
2. Soap bars oral poisoning: are patients with dementia at risk? (abstract no. 29)
Simon De Pralormo, Marion Brunet, Armelle Marquis, Gaël Le Roux, Marie Bretaudeau Deguigne
CHU d’Angers, Angers, France
3. Unusual administration route of an antiparasitic product: a case report (abstract no. 30)
Radu C Tincu, Cristian S Cobilinschi, Radu A Macovei
Carol Davila University, Bucharest, Romania
28
ELECTRONIC POSTERS
THURSDAY 18 MAY 2017 (morning)
10:30 – 11:10
Session chair: Christopher Yates
1. Life-threatening 3,4-methylenedioxy-methamphetamine (MDMA) poisoning: clinical features and
prognostic value of MDMA and its major metabolite concentrations on admission (abstract no. 105)
Taissa Zavgorodniaia (1), Marion Soichot (2), Sébastian Voicu (1), Isabelle Malissin (1), Antoine Goury (1), Lamia
Kerdjana (1), Pierre Garçon (1), Nicolas Deye (1), Emmanuel Bourgogne (2), Bruno Mégarbane (1)
(1)
Department of Medical and Toxicological Critical Care, Lariboisière Hospital, Paris, France; (2) Laboratory of
Toxicology, Lariboisière Hospital, Paris, France
2. Cathinones, and in particular mephedrone, remain the biggest novel psychoactive substance (NPS)
associated with acute harm and Emergency Department presentations in Europe (abstract no. 106)
David M Wood (1), Alison M Dines (1), Knut Erik Hovda (2), Fridtjof Heyerdahl (2), Christopher Yates (3), Isabelle
Giraudon (4), Paul I Dargan (5), Euro-DEN Plus Research Group (1)
(1)
Guy’s and St Thomas’ NHS Foundation Trust London, UK; (2) Oslo University Hospital, Oslo, Norway; (3)
Hospital Universitari Son Espases, Mallorca, Spain; (4) European Monitoring Centre for Drugs and Drug
Addiction (EMCDDA), Lisbon, Portugal; (5) Guy’s and St Thomas’ NHS Foundation Trust, London, UK
3. Emergence of fentanyls on the Swedish novel psychoactive substance market: analytically confirmed
intoxications from the STRIDA project (abstract no. 107)
Matilda Bäckberg (1), Niklas Johansson (2), Olof Beck (2), Anders Helander (2)
(1)
Swedish Poisons Information Centre, Stockholm, Sweden; (2) Karolinska Institutet and Karolinska University
Laboratory, Stockholm, Sweden
4. Synthetic cannabinoid receptors agonists (SCRA) toxicity associated with reduced level of consciousness:
an analytically confirmed case series (abstract no. 108)
Matthew S Blundell (1), Paul I Dargan (1), John RH Archer (1), Simon Hudson (2), Alison M Dines (1), Elizabeth
Biswell (1), David M Wood (1)
(1)
Guy’s and St. Thomas’ NHS Foundation Trust, London, UK; (2) LGC Group, Fordham, UK
5. Trends in the surveillance of mephedrone, MDMA and cocaine detected in anonymous pooled street
urine samples: is mephedrone use decreasing in the UK? (abstract no. 109)
John RH Archer (1), Simon Hudson (2), Rachelle Abouchedid (3), James Ho (3), David M Wood (1), Paul I Dargan (1)
(1)
Clinical Toxicology, Guy’s and St Thomas’ NHS Foundation Trust and King’s Health Partner’s and Faculty
of Life Sciences and Medicine, King’s College London, London, UK; (2) LGC Health Sciences, Fordham, UK;
(3)
Clinical Toxicology, Guy’s and St Thomas’ NHS Foundation Trust and King’s Health Partners, London, UK
6. Marijuana and synthetic cannabinoid patterns in a US state with legalized marijuana: a 5-year NPDS
review (abstract no. 110)
Shireen Banerji (1), Christopher Hoyte (1,2)
(1)
Rocky Mountain Poison Center, Denver, US; (2) University of Colorado School of Medicine, Aurora, US
29
ELECTRONIC POSTERS
THURSDAY 18 MAY 2017 (afternoon)
15:45 – 16:15
Session chair: Peter Hultén
1. § Analytically confirmed post-injection delirium/sedation syndrome (PDSS) after olanzapine long-acting
injection (abstract no. 132)
Valeria M Petrolini (1), Giulia Scaravaggi (1), Eleonora Buscaglia (1), Concettina Lambiase (2), Maddalena Carbone
(2)
, Elisa Roda (1), Teresa Coccini (1), Carlo A Locatelli (1)
(1)
Pavia Poison Control Center - National Toxicology Information Centre, Clinical and Experimental Lab,
Toxicology Unit, Maugeri Clinical and Scientific Institutes IRCCS and University of Pavia, Pavia, Italy; (2) Servizio
di Anestesia e Rianimazione, Azienda Ospedaliera Regionale, San Carlo, Potenza, Italy
2. Incidence and risk factors for hyperlactatemia in patients with metformin overdose (abstract no. 133)
Emily S Taub (1), Robert S Hoffman (2), Alex F Manini (3)
(1)
Emergency Medicine Residency, The Icahn School of Medicine at Mount Sinai, New York, US; (2) NYU School
of Medicine, New York, US; (3) The Icahn School of Medicine at Mount Sinai, New York, US
3. Paracetamol-protein adducts following modified release paracetamol overdose (abstract no. 134)
Angela L Chiew (1), Laura P James (2), Lynda G Letzig (2), Geoffrey K Isbister (3), Nicholas A Buckley (1)
(1)
University of Sydney, Sydney, Australia; (2) Arkansas Children’s Hospital and University of Arkansas for
Medical Sciences, Little Rock, US; (3) University of Newcastle, Newcastle, Australia
4. Survival after varenicline and phentermine overdose with documented serum blood concentrations
(abstract no. 135)
James Barton (1), Anselm Wong (2), Dimitri Gerostamoulos (3), Kerryn Crump (3), Andis Graudins (1)
(1)
Monash Health, Victoria, Australia; (2) Austin Health, Victoria, Australia; (3) Victorian Institute of Forensic
Medicine, Victoria, Australia
FRIDAY 19 MAY 2017 (morning)
10:30 – 11:10
Session chair: Paul Dargan
1. The role of expert identification of spiders in the correct management of spider bites: a pilot study from
Pavia Poison Control Centre (abstract no. 224)
Marta Crevani (1), Carlo M Legittimo (2), Mara Garbi (1), Enrico Simeon (2), Davide Lonati (1), Sarah Vecchio (1), Carlo A Locatelli (1)
(1)
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental Lab,
Toxicology Unit, Maugeri Clinical and Scientific Institutes IRCCS and University of Pavia, Pavia, Italy; (2)
Aracnofilia – Italian Association of Arachnology, Cervignano del Friuli, Udine, Italy
2. Spider bite: a rare case of cutaneous loxoscelism in the west of Iran (abstract no. 225)
Ahmad Ghoochani Khorasani (1), Zahra Fakherdanesh (2)
(1)
Valiasr Hospital, Amin Police University, Islamic Republic of Iran; (2) Valiasr Hospital, Tehran University of
Medical Sciences, Islamic Republic of Iran
3. A case of Fallopia multiflora-induced hepatotoxicity treated with acetylcysteine (abstract no. 226)
Yit H Leang, Anselm Wong, Shaun L Greene
Austin Health, Victoria, Australia
§ Shortlisted for Taylor & Francis best case study award
30
ELECTRONIC POSTERS
FRIDAY 19 MAY 2017 (morning) (cont)
10:30 – 11:10
4. Cardiotoxic hyperkalemia as a result of canary seed ingestion (abstract no. 227)
Emily S Taub, Ruben E Olmedo
The Icahn School of Medicine at Mount Sinai, New York, US
5. French health national survey on poisoning by mushrooms (abstract no. 228)
Chloé Bruneau (1), Nathalie Frébet (1), Sandra Sinno-Tellier (2), Marion Brunet (1), Corinne Schmitt (3), Corinne
Pulce (4), Noël Amouroux (5), Arnaud Courtois (6), Patrick Nisse (7), Antoine Villa (8), Elisabeth Gomes (9), Nadia
Ihadadene (10), Anne Landreau (11), Gaël Le Roux (1)
(1)
CHU d’Angers, Angers, France; (2) Santé Publique France, Paris, France; (3) APHM, Marseille, France; (4) CHU de
Lyon, Lyon, France; (5) CHU de Toulouse, Toulouse, France; (6) CHU de Bordeaux, Bordeaux, France; (7) CHU de
Lille, Lille, France; (8) APHP, Paris, France; (9) CHU de Nancy, Nancy, France; (10) CHU de Strasbourg, Strasbourg,
France; (11) Université d’Angers, Angers, France
6. Role of superoxide dismutase in severe mushroom poisoning: a case report (abstract no. 229)
Radu C Tincu, Cristian S Cobilinschi, Radu A Macovei
Carol Davila University, Bucharest, Romania
FRIDAY 19 MAY 2017 (afternoon)
15:45 – 16:15
Session chair: Mark Zammit
1. Can duration of hemodialysis be estimated based on the on-arrival laboratory tests and clinical
manifestations in methanol-poisoned patients? (abstract no. 245)
Abdolkarim Pajoumand, Nasim Zamani, Hossein Hassanian-Moghaddam, Shahin Shadnia
Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran
2. Emergency anesthetic management of dapsone-induced methemoglobinemia: a case report (abstract
no. 246)
Radu C Tincu, Cristian S Cobilinschi, Radu A Macovei
Carol Davila University, Bucharest, Romania
3. Fetal deaths as reported to the US National Poison Data System, 2011-2015 (abstract no. 247)
Kristin McCloskey, David Goldberger, David Vearrier
Drexel University College of Medicine, Philadelphia, US
4. Role of a poison centre in the management of suspected rabies infections (abstract no. 248)
Carlotta Giandini, Valeria M Petrolini, Marta Crevani, Eleonora Buscaglia, Giulia Scaravaggi, Mara Garbi,
Davide Lonati, Carlo A Locatelli
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental Lab,
Toxicology Unit, Maugeri Clinical and Scientific Institutes IRCCS and University of Pavia, Pavia, Italy
31
POSTERS
WEDNESDAY 17 MAY 2017
Analytical and forensic toxicology
37
(Il-)legal psychoactive ingredients of recreational drugs or dietary supplements: recent findings in a
regional toxicology labatory
Dieter Müller (1), Hartmud Neurath (1), Annette Groeneveld (1), Adrienne Kilian (1), Gesine Liebetrau (2), Marcel
Grapp (1)
(1)
University Medical Center, Göttingen, Germany; (2) Helios Klinikum Erfurt, Erfurt, Germany
38
Clinical and analytical aspects of quetiapine ingestion: a case report Roberto Zoppellari (1), Ilaria Farinelli (1), Cesare Bertocco (2), Evelina Fortini (1), Giovanna Felisatti (1), Anna L
Pinamonti (1), Anna Talarico (2), Rosa M Gaudio (2)
(1)
S. Anna University Hospital, Ferrara, Italy; (2) Ferrara University, Ferrara, Italy
39
Disintegration and possible bezoar formation of large sized extended release tablets: an in vitro study
Anita Annas (1), Mark Personne (1), Steen H Pedersen (2), Frank Refsgaard (2), Georgios Panagiotidis (3), Shahid
Ullah (3), Lotte CG Hoegberg (4)
(1)
Swedish Poisons Information Centre, Stockholm, Sweden; (2) Faculty of Health and Medical Sciences,
University of Copenhagen, Copenhagen, Denmark; (3) Division of Clinical Pharmacology, Karolinska Institutet,
Stockholm, Sweden; (4) The Danish Poisons Information Centre, Copenhagen University Hospital Bispebjerg,
Copenhagen, Denmark
40
Enzalutamide (Xtandi®) and analytical interference during the determination of digoxin
Marion Brunet, Bénédicte Lelièvre, Florence Jégou, Chadi Abbara, Alain Turcant, Gaël Le Roux, Marie
Bretaudeau Deguigne
CHU d’Angers, Angers, France
41
Is semi-quantitative toxicological screening in serum using mass spectrometry helpful in triaging
intoxicated patients at the Emergency Department? The TOXIC study
Pauline M Verputten (1), Saskia J Rietjens (1), Irma S Van Den Hengel-Koot (1), Erik M Van Maarseveen (2), Douwe
Dekker (3), Karin AH Kaasjager (3), Irma de Vries (1), Dylan W De Lange (1,4), Laura Hondebrink (1)
(1)
Dutch Poisons Information Center, University Medical Center Utrecht (UMCU), Utrecht, The Netherlands;
(2)
Department of Clinical Pharmacy, UMCU, Utrecht, The Netherlands; (3) Department of Internal Medicine,
UMCU, Utrecht, The Netherlands; (4) Department of Intensive Care Medicine, UMCU, Utrecht, The
Netherlands
42
Onsite oral fluid detection for ketamine
Dong-Zong Hung (1), Jing-Hua Lin (1), Yu-Chen Lin (2)
(1)
China Medical University Hospital, Taichung City, Taiwan;
Taiwan
32
(2)
National Chen-Kung University, Tainan City,
POSTERS
WEDNESDAY 17 MAY 2017
Analytical and forensic toxicology (cont)
43
Plasma metformin concentration as a diagnostic and prognostic tool for metformin-associated lactic
acidosis (MALA)
Shasine Veli (1), Lydmila Neykova (1), Silviya Stoykova (2), Boriana Mechkarska (2), Vasil Atanasov (2), Evgenia
Stankova (3)
(1)
Clinic of Urgent Toxicology, Military Medical Academy, Sofia, Bulgaria; (2) Analytical Toxicology Laboratory,
Military Medical Academy, Sofia, Bulgaria; (3) Bulgarian Society of Clinical Toxicology, Sofia, Bulgaria
44
Potential pharmacobezoar formation of extended-release tablets and their dissolution: an in vitro study
Lotte CG Hoegberg (1), Frank Refsgaard (2), Steen H Pedersen (2), Mark Personne (3), Shahid Ullah (4), Georgios
Panagiotidis (4), Anita Annas (3)
(1)
Department of Anaesthesiology, The Danish Poisons Information Center, Copenhagen University Hospital
Bispebjerg, Copenhagen, Denmark; (2) Department of Pharmacy, Faculty of Health and Medical Sciences,
University of Copenhagen, Copenhagen, Denmark; (3) The Swedish Poisons Information Centre, Stockholm,
Sweden; (4) Department of Laboratory Medicine, Division of Clinical Pharmacology, Karolinska University
Hospital, Stockholm, Sweden
45
Red blood cell acetylcholinesterase (RBC-AChE) assay as a first indicative marker in organophosphate
poisoning
Lydmila Neykova (1), Vera Traykova (1), Silviya Stoykova (2), Vasil Atanasov (2), Evgenia Stankova (3)
(1)
Clinic of Urgent Toxicology, Military Medical Academy, Sofia, Bulgaria; (2) Analytical Toxicology Laboratory,
Military Medical Academy, Sofia, Bulgaria; (3) Bulgarian Society of Clinical Toxicology, Sofia, Bulgaria
Antidotes
46
A case report of vasoplegic shock treated with methylene blue
Therese Becker, Angela L Chiew, Betty SH Chan
Prince of Wales Hospital, Randwick, Australia
47
Acute ethylene glycol poisoning and methemoglobinemia after engine coolant ingestion treated with
fomepizole and methylene blue
Michael Toce (1), Alex Brevil (2), Matthew Griswold (3), Rebecca Bruccoleri (1), Timothy Erickson (2), Michele Burns (1)
(1)
Boston Children’s Hospital, Boston, US; (2) Brigham and Women’s Hospital, Boston, US; (3) University of
Massachusetts Medical School, Worchester, US
48
An academic hospital’s reassuring experience with flumazenil
Cynthia H Koh, Daniel Lasoff, Bryan Corbett, Cammie Nguyen, Nancy Glober, Allyson Kreshak
University of California, San Diego, US
33
POSTERS
WEDNESDAY 17 MAY 2017
Antidotes (cont)
49
Balancing the publication bias: 45 cases of failed lipid rescue
Susan C Smolinske (1), Eric Villeneuve (2), Robert S Hoffman (3), Sophie Gosselin (2)
(1)
University of New Mexico Poison and Drug Information Center, Albuquerque, US; (2) McGill University
Health Centre, Montréal, Canada; (3) New York University School of Medicine, New York, US
50
Chemical injury: 4 years’ experience with an advanced approach
Jozef Verbelen (1), Henk Hoeksema (1), Stan Monstrey (2)
(1)
Burn Care Coordinator, Ghent, Belgium; (2) Head of Burn Centre, Ghent, Belgium
51
Novel use of sodium thiosulphate: the treatment of calciphylaxis
Jiri Hlusicka (1), Sergey Zakharov (1), Eva Veisova (1), Martin Ullrych (2), Jaroslav Kubecek (3)
(1)
Charles University in Prague, Prague, Czech Republic; (2) Hospital Decin, Decin, Czech Republic; (3) Hospital
Nachod, Nachod, Czech Republic
52
Characterizing the administration of fomepizole by medical toxicologists
Ryan Surmaitis, Kristin McCloskey, David Goldberger, David Vearrier
Drexel University College of Medicine, Philadelphia, US
Heavy metals poisoning
53
Arsenic at breakfast, lunch and dinner
Steven A Seifert, Brandon J Warrick, Susan C Smolinske
University of New Mexico Health Sciences Center, Albuquerque, US
54
Attempted suicide with intravenous copper sulphate: a case report
Ornella Spagnolello (1), Ornella Staltari (2), Alessia Garramone (1), Laura Lombardi (3), Davide Lonati (4), Giuliano
Bertazzoni (1), Maria Caterina Grassi (2)
(1)
Department of Emergency Medicine, Policlinico Umberto I - “Sapienza” University of Rome, Rome, Italy;
(2)
Emergency Toxicology and Poison Control Centre Unit, Policlinico Umberto I - “Sapienza” University of
Rome, Rome, Italy; (3) Department of Immunohematology and Transfusion Medicine, Policlinico Umberto I “Sapienza” University of Rome, Rome, Italy; (4) Pavia Poison Control Center - National Toxicology Information
Centre, Toxicology Unit, Maugeri Clinical and Scientific Institutes IRCCS and University of Pavia, Pavia, Italy
55
Lead poisoning screening in children: an example from France, 2002-2013
Fanny Pélissier (1), Olivier Guilbert (1), Damien Mouly (2), Camille Lecoffre (2), Nicolas Franchitto (1)
(1)
Toulouse-Purpan University Hospital, Toulouse, France; (2) The French Toxicovigilance Network, Toulouse,
France
34
POSTERS
WEDNESDAY 17 MAY 2017
Heavy metals poisoning (cont)
56
Lead poisoning in a family due to incense burning
Yun-Jung Tseng (1), Chun-Hung Chen (2), Dong-Zong Hung (2)
(1)
Department of Emergency Medicine, China Medical University Hospital, Taichung, Taiwan; (2) Division of
Toxicology, Department of Emergency Medicine, China Medical University Hospital, Taichung, Taiwan
57
Mercury vapor poisoning associated with home gilding Ming-Ling Wu, Jou-Fang Deng, Chen-Chang Yang
Taipei Veterans General Hospital, Taipei, Taiwan
58
Severe elemental mercury poisoning managed with selenium and N-acetylcysteine supplementation
Henry A Spiller
Central Ohio Poison Center, Columbus, US
59
Fatal ingestion of copper sulfate
Anne Stürzebecher, Dagmar Prasa, Michael Deters, Helmut Hentschel
Poisons Information Centre Erfurt, Erfurt, Germany
Miscellaneous
60
“Hemp oil” ingestion: the dangers of alternative therapies
Angela L Chiew, Steven Keogh
The Children’s Hospital at Westmead, Westmead, Australia
§ 61
A delicious meal!
Christine Tournoud (1), Laurent Berthelon (1), Agnès Goetzmann (2), Catherine Reitzer (3), Calliope Dirand (1), Eric
Bayle (1), Cécile Kermin (2)
(1)
Centre anti poison et de toxicovigilance, Strasbourg, France; (2) Direction Départementale de la Protection
des Populations, Strasbourg, France; (3) Agence Régionale de Santé Grand Est, Strasbourg, France
62
Carbon monoxide: a hidden threat in Shisha bars
Jutta Trompelt, Oliver Sauer, Andreas Stürer
Medical University of Mainz, Mainz, Germany
63
Cold gel packs: harmless or not?
Tina Nyman, Mikko J Parry, Kalle Hoppu
HUCH Emergency Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
§ Shortlisted for Taylor & Francis best case study award
35
POSTERS
WEDNESDAY 17 MAY 2017
Miscellaneous (cont)
§ 64
Four fatalities after ingestion of vinegar essence
Tara Arif, Kinga Bartecka-Mino, Dieter Genser, Helmut Schiel
Poisons Information Centre, Vienna, Austria
65
Iatrogenic medication errors in residential and care homes
Mandy Gollmann, Dagmar Prasa, Anne Stürzebecher, Michael Deters
Poisons Information Centre Erfurt, Erfurt, Germany
66
Intravenous lipid emulsion: interference with laboratory analyses
Kasper M Petersen, Søren Bøgevig, Tonny S Petersen, Kim P Dalhoff, Mikkel B Christensen
Bispebjerg and Frederiksberg University Hospitals, Copenhagen, Denmark
67
Nationwide survey to evaluate the differences in resources, implementation and treatment strategies for
management of the alcohol withdrawal syndrome (AWS) in England and Wales
Ajay K Gupta (1), Rachelle Abouchedid (1), Shantelle Quashie (1), Gurbachan Bilku (1), David M Wood (2), Paul I
Dargan (2), John RH Archer (2)
(1)
Guy’s and St Thomas’ NHS Foundation Trust and King’s Health Partner’s, London, UK; (2) Clinical Toxicology,
Guy’s and St Thomas’ NHS Foundation Trust and King’s Health Partner’s and Faculty of Life Sciences and
Medicine, King’s College London, London, UK
68
Nosocomial transmission of Clostridium butyricum type E responsible for two cases (one outbreak) of
infant botulism
Davide Lonati (1), Azzurra Schicchi (1), Bruna Auricchio (2), Valeria M Petrolini (1), Fabrizio Anniballi (2), Carlo A Locatelli (1).
(1)
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental Lab,
Toxicology Unit, Maugeri Clinical and Scientific Institutes IRCCS and University of Pavia, Pavia, Italy; (2)
National Reference Centre for Botulism (NRCB), Department of Veterinary Public Health and Food Safety,
National Institute of Health (ISS), Rome, Italy
69
Pre-workout supplements: an analysis of their chemical content and pharmacodynamic interactions with
monoamine transporters Anna Rickli, Matthias E Liechti
Clinical Pharmacology and Toxicology, Department of Biomedicine, University Hospital Basel, University of
Basel, Switzerland
§ Shortlisted for Taylor & Francis best case study award
36
POSTERS
WEDNESDAY 17 MAY 2017
Miscellaneous (cont)
70
Wound botulism in Italy (1979-2016)
Bruna Auricchio (1), Davide Lonati (2), Marta Crevani (2), Elisa Lainu (2), Francesca Chiara (2), Carlo A Locatelli (2),
Fabrizio Anniballi (1)
(1)
National Reference Centre for Botulism (NRCB), Department of Veterinary Public Health and Food Safety, National
Institute of Health (ISS), Rome, Italy; (2) Pavia Poison Control Centre - National Toxicology Information Centre - Clinical
and Experimental Lab, Toxicology Unit, Maugeri Clinical and Scientific Institutes IRCCS and University of Pavia, Pavia, Italy
71
Accidental ingestion of nicotine solution for e-cigarettes: a case report
Michele S Milella, Cristiano Ialongo, Susanna M Signoretti, Maria Caterina Grassi
Emergency Toxicology and Poison Control Centre Unit, Policlinico Umberto I and “Sapienza” University of
Rome, Rome, Italy
Pesticide poisoning
72
Clinical and social features in acute organophosphate pesticide poisoning in school children: a 5 year
retrospective study
Viorela Nitescu (1), Ana Oglinda (2), Nicolae Stanciu (2), Liliana Schirca (2), Victoria Lupu (2), Tatiana Sertinean (2),
Cristina Oglinda (3), Casian Mihai (3)
(1)
Pediatric Poisoning Center Emergency Clinical Hospital for Children “Grigore Alexandrescu”, Bucharest,
Romania; (2) Department of Resuscitation and Toxicology, the Institute of Mother and Child, Chisinau, Republic
of Moldova; (3) University of Medicine and Pharmacy “Nicolae Testemitanu”, Chisinau, Republic of Moldova
73
Different clinical courses for poisoning with World Health Organization hazard class Ia organophosphates
Jeong Mi Moon, Byeong Jo Chun, Young Soo Cho
Chonnam National University Hospital, Gwagngju, Republic of Korea
74
In-hospital outcome and delayed neurologic sequelae of seizures in patients with endosulfan poisoning
Byeong Jo Chun, Jeong Mi Moon, Young Soo Cho
Chonnam National University Hospital, Gwagngju, Republic of Korea
75
Initial laboratory parameters and correlation to intermediate syndrome in patients with acute
organophosphate poisoning
Byeong Jo Chun, Jeong Mi Moon, Hyunn Ho Ryu
Chonnam National University Hospital, Gwagngju, Republic of Korea
§ 76
An outbreak of bromadiolone poisoning after ingestion of treated rice
Chun-Hung Chen, Yun-Jung Tseng, Dong-Zong Hung
China Medical University Hospital, Taichung, Taiwan
§ Shortlisted for Taylor & Francis best case study award
37
POSTERS
WEDNESDAY 17 MAY 2017
Poisons centre activities
77
The economic efficiency of the Belgian Poison Centre and its impact on national healthcare expenses
Anne-Marie K Descamps (1), Dominique M Vandijck (2)
(1)
Poison Centre, Brussels, Belgium; (2) Department of Public Health of Ghent University, Ghent, Belgium
78
Calls to the Finnish Poison Information Centre concerning poisoning during pregnancy 2001-2015
Mervi Saukkonen (1), Liisa Sillanpää (1), Heli Malm (2), Kalle Hoppu (1)
(1)
Poison Information Centre, HUCH Emergency Care, University of Helsinki and Helsinki University Hospital,
Helsinki, Finland; (2) Teratology Information Service, HUCH Emergency Care, University of Helsinki and
Helsinki University Hospital, Helsinki, Finland
79
Changes in smoking habits and the sales of nicotine replacement therapy seem to explain the variation in
the number of calls to FPIC concerning nicotine exposure
Pirjo Tynjälä (1), Katja Valkeapää (2), Mikko J Parry (1), Markku Pasanen (2), Kalle Hoppu (1)
(1)
Poison Information Centre, Helsinki, Finland; (2) University of Eastern Finland, School of Pharmacy, Kuopio, Finland
80
Exposure to fabric protector sprays: analysis of trends and clinical features reported to the UK National
Poisons Information Service, 2008-2014
Michael I Crockett (1), John P Thompson (1), Sally M Bradberry (2), Euan A Sandilands (3), Simon HL Thomas (4),
James M Coulson (1)
(1)
National Poisons Information Service, Cardiff, UK; (2) National Poisons Information Service, Birmingham, UK;
(3)
National Poisons Information Service, Edinburgh, UK; (4) National Poisons Information Service, Newcastle, UK
81
How tackling an increase in call volume resulted in a drop of complaints at a Poisons Information Center (PIC)
Iris Venster, Claudine C Hunault, Anja P Wijnands-Kleukers, Tessa E Van Riemsdijk, Irma de Vries
University Medical Center Utrecht (UMCU), Utrecht, The Netherlands
82
Human tilmicosin exposures, clinical features and outcome: a review of enquiries received by the UK NPIS,
2008-2016
Eleri Thomas (1), Sally M Bradberry (2), Euan A Sandilands (3), Simon HL Thomas (4), John P Thompson (1)
(1)
UK National Poisons Information Service, Cardiff, UK; (2) UK National Poisons Information Service, Birmingham, UK;
(3)
UK National Poisons Information Service, Edinburgh, UK; (4) UK National Poisons Information Service, Newcastle, UK
83
Impact of Zika virus spread on a Florida Poison Information Center
Tamas R Peredy (1), Alfred Aleguas (2)
(1)
University of South Florida, Tampa, US; (2) Tampa General Hospital, Tampa, US
38
POSTERS
WEDNESDAY 17 MAY 2017
Poisons centre activities (cont)
84
Primary poisoning prevention and awareness: the Estonian experience
Ruth Kastanje (1), Mare Oder (2)
(1)
Estonian Poison Information Centre, Tallinn, Estonia; (2) Estonian Health Insurance Fund, Tallinn, Estonia
85
Publicity as a public relation strategy in poisons information centre survival
Michaela Strautins, Lotte CG Hoegberg
Department of Anaesthesiology, The Danish Poisons Information Centre, Copenhagen University Hospital
Bispebjerg, Copenhagen, Denmark
86
Risks from and concerns about methamphetamine exposures: a review of enquiries to the New Zealand
Poisons Centre
Michael G Beasley, Lucy M Shieffelbien
University of Otago, Dunedin, New Zealand
87
The CLP Unique Formula Identifier (UFI) for hazardous mixtures will help poisons centres (PC) give the best
advice and will increase the value of PC case records for regulatory risk assessment under REACH
Herbert Desel
Federal Institute for Risk Assessment (BfR), Berlin, Germany
88
The role of the Serbian National Poison Control Center in the management of poisoning in children
Jasmina Jović-Stošič, Slavica Vucinic, Tomislav Rezic, Jasmina Pavlovic Baaklini, Gordana Vuković-Ercegović
National Poison Control Centre, Military Medical Academy, Belgrade, Serbia
89
Therapeutic errors: the experience of the Florence Poison Center
Arianna Dilaghi (1), Marco Cirronis (1), Francesco Gambassi (2), Brunella Occupati (2), Alessandra Ieri (2), Guido
Mannaioni (1), Andrea Missanelli (2), Emanuela Masini (1), Alessandra Pistelli (2)
(1)
Department of NEUROFARBA, Section of Pharmacology and Toxicology, University of Florence, Firenze,
Italy; (2) Clinical Toxicology Unit, Azienda Ospedaliero Universitaria Careggi, Firenze, Italy
90
Trends in enquires to the UK National Poisons Information Service (NPIS) involving “preschool” (0-4 years)
children in 2015. Might knowledge of circumstances help plan prevention strategies?
Nicola Wheatley (1), Gillian A Cooper (1), John P Thompson (1), Sally M Bradberry (2), Euan A Sandilands (3), Simon
HL Thomas (4)
(1)
UK National Poisons Information Service, Cardiff, UK; (2) UK National Poisons Information Service,
Birmingham, UK; (3) UK National Poisons Information Service, Edinburgh, UK; (4) UK National Poisons
Information Service, Newcastle, UK
39
POSTERS
WEDNESDAY 17 MAY 2017
Poisons centre activities (cont)
91
Venlafaxine overdoses reported to the UK National Poisons Information Service over a 5 year period
Michael I Crockett (1), John P Thompson (1), Sally M Bradberry (2), Euan A Sandilands (3), Simon HL Thomas (4),
James M Coulson (1)
(1)
UK National Poisons Information Service, Cardiff, UK; (2) UK National Poisons Information Service,
Birmingham, UK; (3) UK National Poisons Information Service, Edinburgh, UK; (4) UK National Poisons
Information Service, Newcastle, UK
92
Vietnamese centipede: a new trend in dangerous pets?
Rachel Vickery (1), Sally M Bradberry (2), Euan A Sandilands (3), Simon HL Thomas (4), John P Thompson (1)
(1)
UK National Poisons Information Service, Cardiff, UK; (2) UK National Poisons Information Service,
Birmingham, UK; (3) UK National Poisons Information Service, Edinburgh, UK; (4) UK National Poisons
Information Service, Newcastle, UK
Toxicosurveillance
93
The impact of repackaging from bottle to blister on paediatric intoxications with the levothyroxine brand
Thyrax®
Antoinette JHP van Riel, Tessa E van Riemsdijk, Claudine C Hunault, Irma de Vries
University Medical Center Utrecht (UMCU), Utrecht, The Netherlands
Veterinary toxicology
94
Alphachloralose poisoning in dogs: a case series
Anita Annas (1), Frida Norrvik (2), Lis-Marie Johansson (2)
(1)
Swedish Poisons Information Centre, Stockholm, Sweden; (2) AniCura Animal Hospital, Falun, Sweden
95
Fatal mushroom poisoning in a dog
Andrea Gleed (1), Michael Jordan (2), Nicola Bates (3), Azar Alexander-Sefre (3), Nick Edwards (3)
(1)
Vets4Pets, Hull, UK; (2) Fungus Conservation Trust, Axminster, UK; (3) Veterinary Poisons Information Service
(VPIS), London, UK
96
Gabapentin ingestion in dogs and cats Lilia Kazemi-Egbunike, Nicola Bates
Veterinary Poisons Information Service (VPIS), London, UK
40
POSTERS
WEDNESDAY 17 MAY 2017
Veterinary toxicology (cont)
97
Lamotrigine is cardiotoxic to dogs
Nicola Bates, Nick Edwards, Zoe Tizzard
Veterinary Poisons Information Service (VPIS), London, UK
98
Metaldehyde ingestion in 18 domestic equines
Tiffany Blackett, Nicola Bates
Veterinary Poisons Information Service (VPIS), London, UK
99
Neonicotinoid insecticide exposure in cats and dogs
Stella Matumo, Nicola Bates
Veterinary Poisons Information Service (VPIS), London, UK
100
Phenoxyacetic acid derivative herbicide exposure in 101 dogs
Niamh Allen, Nicola Bates
Veterinary Poisons Information Service (VPIS), London, UK
101
Pregabalin ingestion in dogs and cats
Nicola Robinson, Nicola Bates
Veterinary Poisons Information Service (VPIS), London, UK
102
Suspected synthetic cannabinoid ingestion in dogs: a case series
Mark Van-de-Velde, Nicola Bates, Nick Edwards
Veterinary Poisons Information Service (VPIS), London, UK
103
Accidental poisoning in dogs from intraruminal monensin devices expelled by cows
Jonas Van Baelen, Geert Verstegen, Martine Mostin
Belgian Poison Centre, Brussels, Belgium
104
Comparison of the Poisoning Severity Score and National Poison Data System schemes for severity
assessment of dog poisonings
Sarah McFarland (1), Alvin Bronstein (2), Shireen Banerji (3), Jane Leblond (4), Kathrin Begemann (1), Matthias
Greiner (1)
(1)
Federal Institute of Risk Assessment, Berlin, Germany; (2) Hawaii State Department of Health, Honolulu, US; (3)
Rocky Mountain Poison and Drug Centre, Denver, US; (4) Creighton University School of Pharmacy, Omaha, US
41
POSTERS
THURSDAY 18 MAY 2017
Adverse effects
139
A hard drug error: naloxogel-induced opioid withdrawal
Morgan AA Riggan (1), Donald B Robinson (2), Robert S Hoffman (1), Patricia Phan (3), Silas W Smith (1), Rana Biary (1)
(1)
NYU School of Medicine, New York, US; (2) New York City Control Center, New York, US; (3) St. Francis Hospital,
Roslyn, US
140
Antiepileptic drug-induced hypocalcemia as the main cause of uncontrolled seizures in long-term treatment
of epilepsy Gabija Mikuleviciene, Robertas Badaras
Republican Vilnius University Hospital, Vilnius, Lithuania
§ 141
Fatal outcome after ingestion of dimethyl sulfoxide as a miracle cure
Nina Glaser (1), Johannes Manhart (2), Maren Oldörp (3), Miriam Friedemann (1), Herbert Desel (1)
(1)
Federal Institute for Risk Assessment, Berlin, Germany; (2) Rostock University Medical Center, Rostock,
Germany; (3) Municipal Hospital Südstadt Rostock, Rostock, Germany
142
Fatalities in low-weight children related to supratherapeutic doses of paracetamol in countries with
unrestricted access to medication
Mohamad Haidar (1), Kensute Tkahashi (1), Nicoletta Belio (2), Jean-Claude Alvarez (3), Robin E Ferner (4), Luke
Bawo (5), Klaudia Porten (1), Frederic J Baud (2)
(1)
Epicentre, Paris, France; (2) Médecins Sans Frontières, Paris, France; (3) AP-HP; University VSQ, Paris, France;
(4)
City Hospital, Birmingham, UK; (5) Ministry of Health and Social Welfare, Monrovia, Liberia
143
Generalised tonic-clonic seizures provoked after short term over-the-counter treatment with a combination
of pseudoephedrine hydrochloride, paracetamol and dextromethorphan hydrobromide
Mojca Dobaja, Damjan Grenc, Miran Brvar
University Medical Centre Ljubljana, Ljubljana, Slovenia
144
Hepatotoxicity of tyrosine kinase inhibitors
Franziska Paech, Jamal Bouitbir, Stephan Krähenbühl
University of Basel, Basel, Switzerland
145
Hypersensitivity secondary to naltrexone depot injection
David Goldberger (1), Suraj Rajasimhan (2), Alin Gragossian (1), Rita McKeever (1), David Vearrier (1), Michael I
Greenberg (1)
(1)
Drexel University College of Medicine, Philadelphia, US; (2) Hahnemann University Hospital, Philadelphia, US
§ Shortlisted for Taylor & Francis best case study award
42
POSTERS
THURSDAY 18 MAY 2017
Adverse effects (cont)
146
Monoclonal antibodies and other immunomodulating drugs: enquiries to a poisons information service
Alison M Good (1), Gillian Jackson (1), Caroline McGrory (1), Simon HL Thomas (2), John P Thompson (3), Sally M
Bradberry (4), Euan A Sandilands (1)
(1)
NPIS Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, UK; (2) NPIS Newcastle, Regional Drug and
Therapeutics Centre, Newcastle upon Tyne, UK; (3) NPIS Cardiff, University Hospital Llandough, Cardiff, UK; (4)
NPIS Birmingham, City Hospital, Birmingham, UK
147
Pediatric cardiac arrest after Cyclomydril(R) eye drops
Eike Blohm, Jeffrey T Lai
University of Massachusetts, Worcester, US
§ 148
Perampanel overdose causing a prolonged dissociated state Kai Li, Daniel Lasoff, Craig Smollin, Binh Ly
California Poison Control Center, San Francisco, US
149
Predicting clinically relevant drug induced liver injury
Felix Hammann, Jürgen Drewe
University and University Hospital Basel, Basel, Switzerland
150
Take a big GuLP: recurrent hypoglycemia from liraglutide responds to octreotide
Rana Biary, Lindsay M Fox, Robert S Hoffman
NYU School of Medicine, New York, US
151
The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the
mitochondrial respiratory chain in HepaRG cells
David Grünig, Andrea Felser, Jamal Bouitbir, Stephan Krähenbühl
University Hospital, Basel, Switzerland
152
The impact of polypharmacy and drug interactions on the onset of adverse drug reactions Marco Morina, Pierpaolo Cascino, Giscardo F Panzavolta, Andrea F Stella, Adriana M Tomoiaga, Franca
Davanzo
Milan Poison Control Center, Milan, Italy
§ Shortlisted for Taylor & Francis best case study award
43
POSTERS
THURSDAY 18 MAY 2017
Drug abuse poisoning
153
Acute “bath salts” intoxications: analytical findings and clinical features
Tobias Zellner (1), Marco Diestelmann (2), Liane D Paul (2), Rudolf Pfab (1), Florian Eyer (1)
(1)
Klinikum rechts der Isar – School of Medicine, Technical University of Munich, Munich, Germany;
Institute of Forensic Medicine, Ludwig-Maximilian-University, Munich, Germany
(2)
154
Acute effects after consumption of the novel synthetic cannabinoids 5F-ADB
Bernardino Barceló (1), Isabel Gomila (1), Manuela Pellegrini (2), Verena Angerer (3), Simona Pichini (2), Christopher
Yates (1), Victoria L Corominas (1), Jordi Puiguriguer (1), Volker Auwärter (3)
(1)
Hospital Universitari Son Espases, Research Institute of Health Sciences (IdISPa), Palma de Mallorca, Spain; (2) Istituto
Superiore di Sanità, Rome, Italy; (3) Institute of Forensic Medicine, University of Freiburg Medical Center, Freiburg, Germany
155
Acute health problems due to recreational drug use in patients presenting to an urban emergency
department in Switzerland
Evangelia Liakoni (1), Sabine Müller (1), Adrian Stoller (1), Matthias E Liechti (2), Meret Ricklin (1), Aristomenis K Exadaktylos (1)
(1)
Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; (2) University Hospital Basel and
University of Basel, Basel, Switzerland
156
Acute intoxication involving the new psychoactive substance alpha-pyrrolidinobutiophenone (α-PBP):
results from the Swedish STRIDA project
Lisa Franzén (1), Olof Beck (2), Anders Helander (2), Matilda Bäckberg (1)
(1)
Swedish Poisons Information Centre, Stockholm, Sweden; (2) Karolinska Institutet and Karolinska University
Laboratory, Stockholm, Sweden
157
Addressing the public health impact of new psychoactive substances: early analysis of the effects of the UK’s
Psychoactive Substances Act on poisons centre enquiries related to drugs of misuse
Israa Al Banaa (1), Leonard C Hawkins (2), David J Lupton (3), Gillian Jackson (3), Euan A Sandilands (3), John P
Thompson (4), Sally M Bradberry (5), Simon L Hill (1), Simon HL Thomas (1)
(1)
Newcastle University, Newcastle, UK; (2) Newcastle Hospitals NHS Foundation Trust, Newcastle, UK; (3) Royal
Infirmary of Edinburgh, Edinburgh, UK; (4) Cardiff University Hospital Llandough, Cardiff, UK; (5) Sandwell and
West Birmingham NHS Trust, Birmingham, UK
158
An example of a new toxicological disease and a new social problem related to the abuse of and addiction
to new psychoactive substances
Eleonora Buscaglia (1), Azzurra Schicchi (1), Davide Lonati (1), Giuseppa Calabrò (2), Pietro Papa (3), Antonella Valli
(3)
, Marcello Di Tuccio (3), Carlo A Locatelli (1)
(1)
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental Lab,
Toxicology Unit, Maugeri Clinical and Scientific Institutes IRCCS and University of Pavia, Pavia, Italy; (2)
NESMOS (Neuroscience, Mental Health, and Sensory Organs) Department, Sapienza University, School of
Medicine and Psychology, Sant’Andrea Hospital, Rome, Italy; (3) Laboratory of Analytical Toxicology, Clinical
Chemistry Service, IRCCS Policlinico S. Matteo Foundation, Pavia, Italy
44
POSTERS
THURSDAY 18 MAY 2017
Drug abuse poisoning (cont)
159
An online survey on misuse of benzodiazepines and “Z drugs” in Singapore
Wui Ling Chan (1), David M Wood (2), Colleen M Haynes (3), Karilynn M Rockhill (3), Jody L Green (3), Paul I Dargan (2)
(1)
Tan Tock Seng Hospital, Singapore; (2) Clinical Toxicology, Guy’s and St Thomas’ NHS Foundation Trust
and King’s Health Partners and Faculty of Life Sciences and Medicine, King’s College London, UK; (3) Rocky
Mountain Poison & Drug Center, Denver, US
160
Ayahuasca intoxication: two case reports
Anna Celentano, Marco Morina, Rossana Borghini, Angelo Travaglia, Franca Davanzo
Milan Poison Control Center, Milan, Italy
161
Baclofen poisoning in France reported to French Poison Centers: a five-year retrospective study
Fanny Pélissier (1), Luc De Haro (2), Florence Cardona (3), Cyndie Picot (3), Emmanuel Puskarczyk (4), Jean-Marc
Sapori (5), Christine Tournoud (6), Nicolas Franchitto (1)
(1)
Toulouse-Purpan University Hospital, Toulouse, France; (2) Sainte Marguerite Hospital, Marseille, France; (3)
French National Agency for Medicines and Health Products Safety, Saint Denis, France; (4) Nancy University
Medical Center, Nancy, France; (5) Hospices Civils de Lyon, Lyon, France; (6) Hôpital Civil, Strasbourg, France
162
Capsaicin cream in the treatment of cannabinoid hyperemesis syndrome: relief from the “joint” pain
Zachary T Hafez, David B Liss, Evan S Schwarz, Michael E Mullins
Washington University School of Medicine, Saint Louis, US
163
Clinical features following analytically confirmed use of 5F-ADB, a synthetic cannabinoid receptor agonist. A
report from the UK IONA study Muhammad EMO Elamin (1), Michael Dunn (2), Paul I Dargan (3), David M Wood (3), Simon Tucker (4), Simon L Hill
(2)
, Simon HL Thomas (2)
(1)
Newcastle Hospitals NHS Foundation Trust, Newcastle, UK; (2) Newcastle University, Newcastle, UK; (3) King’s
College London, London, UK; (4) Blackpool Teaching Hospitals NHS Foundation Trust, Blackpool, UK
164
Clinical features in emergency department patients with analytically confirmed intake of ADB-CHMINACA: a
case series from the prospective study SPICE II plus
Maren Hermanns-Clausen (1), Josephine Kithinji (1), Verena Angerer (2), Florian Franz (2), Florian Eyer (3), Volker Auwärter (2)
(1)
Center for Pediatrics, University of Freiburg Medical Center, Faculty of Medicine, University of Freiburg, Freiburg,
Germany; (2) University of Freiburg Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany;
(3)
Internal Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany
45
POSTERS
THURSDAY 18 MAY 2017
Drug abuse poisoning (cont)
165
Clinical features of severe intoxications associated with analytically confirmed use of NBOMe
Carlo A Locatelli (1), Eleonora Buscaglia (1), Antonella Valli (2), Loretta Rocchi (2), Laura Rolandi (2), Marcello Di
Tuccio (2), Giulia Scaravaggi (1), Marta Crevani (1), Pietro Papa (2)
(1)
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental Lab,
Toxicology Unit, Maugeri Clinical and Scientific Institutes IRCCS and University of Pavia, Pavia, Italy and
Clinical-Toxicology Coordinating Centre of the National Early Warning System, Presidency of the Council of
Ministers, Rome, Italy; (2) Laboratory of Analytical Toxicology, Clinical Chemistry Service, IRCCS Policlinico San
Matteo Foundation, Pavia, Italy
166
Cocaethylene formation following ethanol and cocaine use: a case report
Brunella Occupati (1), Angelo Rotulo (1), Filippo Gori (1), Francesco Gambassi (1), Elisabetta Bertol (2), Emanuela
Masini (3)
(1)
Toxicology Unit and Poison Control Center, AOU Careggi, Florence, Italy; (2) Department of Health Science,
Section of Forensic Medicine, Florence, Italy; (3) Toxicology Unit and Poison Control Center, AOU Careggi;
Department of NEUROFARBA, University of Florence, Florence, Italy
167
Comparison of prevalence of illicit recreational drug use in the annual Crime Survey England and Wales and
the UK Survey of Non-Medical Use of Prescription Drugs Programme between 2014 and 2016
David M Wood (1), Jody L Green (2), Colleen M Haynes (2), Karilynn M Rockhill (2), Paul I Dargan (1)
(1)
Guy’s and St Thomas’ NHS Foundation Trust and King’s Health Partners; Faculty of Life Sciences and
Medicine, King’s College London, London, UK; (2) Rocky Mountain Poison & Drug Center, Denver Health,
Denver, US
168
Confirmed intoxication by 2-methoxphenidine and flubromazepam mimicking ischemic cerebral disease
Antonella Valli (1), Marcello Di Tuccio (1), Davide Lonati (2), Mara Garbi (2), Eleonora Buscaglia (2), Pietro Papa (1),
Carlo A Locatelli (2)
(1)
Laboratory of Analytical Toxicology, Clinical Chemistry Service, IRCCS Policlinico S. Matteo Foundation,
Pavia, Italy; (2) Pavia Poison Control Centre - National Toxicology Information Centre-Clinical and Experimental
Lab, Toxicology Unit, Maugeri Clinical and Scientific Institutes IRCCS and University of Pavia, Pavia, Italy
169
Does one affect the other? A 5-year characterization of US Poison Center data comparing human marijuana
and synthetic cannabinoid exposures
Shireen Banerji (1), Christopher Hoyte (1,2)
(1)
Rocky Mountain Poison Center, Denver, US; (2) University of Colorado School of Medicine, Aurora, US
170
Drowning in bath salts: MDPV in northern Germany
Martin Ebbecke, Andreas Schaper, Elke Färber, Annette Groeneveld, Adrienne Kilian, Marcel Grapp
University Medical Center, Göttingen, Germany
46
POSTERS
THURSDAY 18 MAY 2017
Drug abuse poisoning (cont)
171
Gamma-hydroxybutyrate intoxication in Italy related to a pharmaceutical preparation
Valeria M Petrolini (1), Valentina Costa (2), Marta Crevani (1), Giulia Scaravaggi (1), Giorgio Ricci (2), Carlo A Locatelli (1)
(1)
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental Lab,
Toxicology Unit, Maugeri Clinical and Scientific Institutes IRCCS and University of Pavia, Pavia, Italy; (2)
Emergency Department, Universitary Hospital of Verona (AOUI), Verona, Italy
172
Increase in Emergency Department presentations in Europe related to the use of synthetic cannabinoid
receptor agonists
David M Wood (1), Alison M Dines (1), Knut Erik Hovda (2), Fridtjof Heyerdahl (2), Christopher Yates (3), Isabelle
Giraudon (4), Paul I Dargan (1), Euro-DEN Plus Research Group (5)
(1)
Guy’s and St Thomas’ NHS Foundation Trust and Faculty of Life Sciences and Medicine, King’s College
London, London, UK; (2) Oslo University Hospital, Oslo, Norway; (3) Hospital Universitari Son Espases, Mallorca,
Spain; (4) European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), Lisbon, Portugal; (5) Guy’s and
St Thomas’ NHS Foundation Trust, London, UK
173
Moderate and severe carbon monoxide intoxication related to waterpipe use
Valeria M Petrolini, Federico Vigorita, Mara Garbi, Marta Crevani, Francesca Chiara, Carlo A Locatelli
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental Lab,
Toxicology Unit, Maugeri Clinical and Scientific Institutes IRCCS and University of Pavia, Pavia, Italy
174
Necessity of vigilant supervision of body stuffers: a case report Marius Perminas, Egle Zelbiene, Jonas Surkus, Ruta Leksiene, Nedas Jasinskas
Lithuanian University of Health Sciences, Kaunas, Lithuania
175
Non-medical use of loperamide in the UK
Paul I Dargan (1), Colleen M Haynes (2), Patrick May (2), Karilynn M Rockhill (2), David M Wood (1), Jody L Green (2)
(1)
Guy’s and St Thomas’ NHS Foundation Trust, London, UK; (2) Rocky Mountain Poison and Drug Center, Denver, US
176
Novios muertos: two confirmed fatalities from U-47700
Stephen A Harding (1), Rana Biary (1), Robert S Hoffman (1), Mark K Su (2), Gail A Cooper (3), Silas W Smith (1)
(1)
Ronald O. Perelman Department of Emergency Medicine, NYU School of Medicine, New York, US; (2) Ronald O. Perelman
Department of Emergency Medicine, NYU School of Medicine and New York City Poison Control Center, New York, US; (3)
Office of the Chief Medical Examiner and Department of Forensic Medicine, NYU School of Medicine, New York, US
177
Patients self-discharging during treatment for acute poisoning by substances of abuse
Odd Martin Vallersnes (1), Dag Jacobsen (2), Øivind Ekeberg (1), Mette Brekke (1)
(1)
University of Oslo, Oslo, Norway; (2) Oslo University Hospital, Oslo, Norway
47
POSTERS
THURSDAY 18 MAY 2017
Drug abuse poisoning (cont)
178
Patterns of use of licensed medicines in Emergency Department acute recreational drug toxicity presentations
reported to the European Drug Emergencies Network Plus (Euro-DEN Plus)
Alison M Dines (1), Paul I Dargan (1), John RH Archer (1), Knut Erik Hovda (2), Fridtjof Heyerdahl (2), Christopher
Yates (3), Isabelle Giraudon (4), David M Wood (1), Euro-DEN Plus Research Group (1)
(1)
Guy’s and St Thomas’ NHS Foundation Trust and King’s Health Partners, London, UK; (2) Oslo University
Hospital, Oslo, Norway; (3) Hospital Universitari Son Espases, Mallorca, Spain; (4) European Monitoring Centre
for Drugs and Drug Addiction (EMCDDA), Lisbon, Portugal
179
Pregabalin misuse and abuse reported to US Poison Centers
Christopher Hoyte (1,2), Shireen Banerji (2), Alvin Bronstein (3)
(1)
University of Colorado School of Medicine, Aurora, US; (2) Rocky Mountain Poison and Drug Center, Denver,
US; (3) Emergency Medical Services Injury Prevention System Branch, Honolulu, US
§ 180
Recreational carfentanil: the devil in disguise
Sabine Müller (1), Susanne Nussbaumer (2), Gabriel Plitzko (1), Roger Ludwig (1), Wolfgang Weinmann (2), Evangelia Liakoni (1)
(1)
Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; (2) Institute of Forensic Medicine,
University of Bern, Bern, Switzerland
181
Synthetic cannabinoid receptor agonist (SCRA) detection from pooled urine samples in central London
John RH Archer (1), Simon Hudson (2), Rachelle Abouchedid (3), James Ho (3), David M Wood (1), Paul I Dargan (1)
(1)
Guy’s and St Thomas’ NHS Foundation Trust and King’s Health Partner’s and Faculty of Life Sciences and
Medicine, King’s College London, London, UK; (2) LGC Health Sciences, Fordham, UK; (3) Clinical Toxicology,
Guy’s and St Thomas’ NHS Foundation Trust and King’s Health Partners, London, UK
182
Synthetic cannabinoid receptor agonists identified in patients with severe clinical toxicity in England: a
report from the Identification Of Novel psychoActive substances (IONA) study
Simon L Hill (1), Michael Dunn (2), Paul I Dargan (3), David M Wood (3), Simon Tucker (4), Johann Grundlingh (5),
Ashraf Kamour (6), Paul Acheampong (7), Simon HL Thomas (2)
(1)
Newcastle Hospitals NHS Foundation Trust, Newcastle, UK; (2) Newcastle University, Newcastle, UK; (3) King’s
College London, London, UK; (4) Blackpool Teaching Hospitals NHS Foundation Trust, Blackpool, UK; (5) Royal
London Hospital, London, UK; (6) North Manchester General Hospital, Manchester, UK; (7) Royal Liverpool
University Hospital, Liverpool, UK
§ Shortlisted for Taylor & Francis best case study award
48
POSTERS
THURSDAY 18 MAY 2017
Drug abuse poisoning (cont)
183
The migration of drugs of abuse from Europe to Denmark: analysis of pooled anonymous urine from urinals
at Roskilde Festival 2016
Lotte CG Hoegberg (1), Cecilie Christiansen (2), Jesper Soe (3), Rasmus Telving (4), Mette F Andreasen (4), Dan
Staerk (2), Lona L Christrup (2), Kenneth T Kongstad (2)
(1)
Department of Anaesthesiology, The Danish Poisons Information Center, Copenhagen University Hospital
Bispebjerg, Copenhagen, Denmark; (2) Department of Drug Design and Pharmacology, Faculty of Health and
Medical Sciences, University of Copenhagen, Copenhagen, Denmark; (3) Department of Anaesthesiology,
Copenhagen University Hospital Hvidovre, Denmark and Roskilde Festival, Roskilde, Denmark; (4) Department
of Forensic Medicine, Aarhus University, Aarhus, Denmark
§184
The syndrome of inappropriate antidiuretic hormone secretion due to the 3-methyl-N-methylcathinone (3MMC) intoxication
Vid Leban (1), Andrej Fister (2), Miran Brvar (1)
(1)
University Medical Centre Ljubljana, Ljubljana, Slovenia; (2) University of Ljubljana, Ljubljana, Slovenia
185
Use of technology to study bystander naloxone distribution
Jeffrey T Lai (1), Peter R Chai (1), Katherine L Boyle (2), Edward W Boyer (1)
(1)
University of Massachusetts Medical School, Worcester, US; (2) Beth Israel Deaconess Medical Center and
Harvard Medical School, Boston, US
186
Peyote use in the US, 2002-2013
Kristin McCloskey, David Vearrier, Rita McKeever, David Goldberger
Drexel University College of Medicine, Philadelphia, US
187
Cannabis smoke inhalation: an insidious cause of spontaneous pneumothorax in teenagers
Valentina A Ferro, Mara Pisani, Valerio Pardi, Marco Marano, Maria Barbieri, Anna Maria Musolino, Umberto
Raucci, Antonino Reale
Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy
§ Shortlisted for Taylor & Francis best case study award
49
POSTERS
THURSDAY 18 MAY 2017
Medication poisoning (including paracetamol and anti-convulsive drugs)
188
Poisoning severity in intentional self-harm as a function of class of medication ingested
Kenneth R Conner, Timothy J Wiegand, Rachel Gorodetsky, Rachel Schult, Kimberly Kaukeinen
University of Rochester Medical Center, Rochester, US
189
A characterization of gabapentin abuse and misuse reported to US Poison Centers
Christopher Hoyte (1,2), Shireen Banerji (2)
(1)
University of Colorado School of Medicine, Aurora, US; (2) Rocky Mountain Poison and Drug Center, Denver, US
190
A complicating factor: hidden salicylate poisoning in a septic patient
Talan A Parnell, John P Thompson
UK National Poisons Information Service, Cardiff, UK
191
A rare but severe case of minoxidil poisoning in a child
Gaël Le Roux, Jérémy Lecot, Marion Brunet, Florence Jégou, David Boels
CHU d’Angers, Angers, France
192
Moved to Friday 19 May
193
Acute valacyclovir overdose causing renal failure and neurotoxicity
Karin Rafstedt (1), Jonas Höjer (1), Eva K Olsson (1), Jonas Feldthusen (2)
(1)
Swedish Poisons Information Centre, Stockholm, Sweden; (2) Norra Älvsborg Hospital, Trollhättan, Sweden
194
Baclofen self-poisoning: is extrarenal epuration efficient in normorenal patients?
Marion Brunet (1), Gaël Le Roux (1), Maxime Léger (1), Pierre-André Billat (2), Nicolas Lerolle (1), David Boels (1)
(1)
CHU d’Angers, Angers, France; (3) Université d’Angers, Angers, France
195
Cardiovascular findings in acute poisoning with anticonvulsant drugs in children
Iolanda C Vivisenco, Coriolan E Ulmeanu
Emergency Hospital for Children “Grigore Alexandrescu”, Bucharest, Romania
196
Clonidine exposures in children under 6 years: cases reported to Australia’s largest poisons information centre
Rose Cairns (1,2), Jared A Brown (2), Nicholas A Buckley (1)
(1)
New South Wales Poisons Information Centre, The Children’s Hospital at Westmead, Sydney, Australia; (2)
Sydney Medical School, University of Sydney, Sydney, Australia
50
POSTERS
THURSDAY 18 MAY 2017
Medication poisoning (including paracetamol and anti-convulsive drugs) (cont)
197
Delayed Ogilvie Syndrome induced by acute clozapine overdose
Vesna Mijatović (1), Jasmina Jović-Stošič (2), Nataša Perković-Vukčević (2), Gordana Vuković-Ercegović (2), Olivera
Potrebić (2), Snežana Đorđević (2), Zoran Šegrt (3)
(1)
Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine, University of
Novi Sad, Novi Sad, Serbia; (2) National Poison Control Center, Military Medical Academy, Belgrade, Serbia; (3)
Faculty of Medicine of the Military Medical Academy, University of Defence, Belgrade, Serbia
198
Dihydropyridine calcium channel blocker toxicity and the renin angiotensin axis
Betty SH Chan (1), Angela L Chiew (1), Colin B Page (2), Geoffrey K Isbister (3), Buckley A Nicholas (4)
(1)
Prince of Wales Hospital, Sydney, Australia; (2) Princess Alexandra Hospital, Sydney, Australia;
Mater Hospital, Newcastle, Australia; (4) University of Sydney, Sydney, Australia
(3)
Calvary
199
Does serum procalcitonin predict the onset of toxic acute hepatitis in acetaminophen poisoning?
Shireen Salem (1), Antoine Goury (1), Isabelle Malissin (1), Pierre Garçon (1), Lamia Kerdjana (1), Sébastian Voicu (1),
Nicolas Deye (1), Hervé Gourlain (2), Eric Vicaut (3), Bruno Mégarbane (1)
(1)
Department of Medical and Toxicological Critical Care, Lariboisière Hospital, Paris, France; (2) Laboratory of
Toxicology, Lariboisière Hospital, Paris, France; (3) Biostatistics, Lariboisière Hospital, Paris, France
200
Extended-release (XR) quetiapine overdose is associated with delayed development of peak toxicity and
prolonged recovery when compared to immediate-release (IR) quetiapine overdose: a retrospective cohort study
Lucy M Taylor (1), Andis Graudins (2)
(1)
Monash University, Clayton, Australia; (2) Monash Health and Monash University, Dandenong, Australia
201
Favorable acute toxicity profile of morclofone in children
Katharina E Hofer, Hugo Kupferschmidt, Christine Rauber-Lüthy
National Poisons Centre, Tox Info Suisse, Associated Institute of the University of Zurich, Zurich, Switzerland
§ 202
Fomepizole, dialysis and an increased dose of N-acetylcysteine in a case of massive paracetamol ingestion
Åsa Appelqvist (1), Erik Lindeman (2)
(1)
Skaraborg Hospital, Skövde, Sweden; (2) Swedish Poisons Information Centre, Stockholm, Sweden
203
High in-hospital death rate from calcium channel blocker and beta-blocker poisonings
Markus Tellerup, Johanna Nordmark-Grass, Erik Lindeman
Swedish Poisons Information Centre, Stockholm, Sweden
§ Shortlisted for Taylor & Francis best case study award
51
POSTERS
THURSDAY 18 MAY 2017
Medication poisoning (including paracetamol and anti-convulsive drugs) (cont)
204
Methotrexate therapeutic errors in non-oncology settings
Azzurra Schicchi, Valeria M Petrolini, Serena Marra, Maria Mascolo, Francesca Chiara, Giulia Scaravaggi,
Sarah Vecchio, Carlo A Locatelli
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental Lab,
Toxicology Unit, Maugeri Clinical and Scientific Institutes IRCCS and University of Pavia, Pavia, Italy
205
Nearly all cases of clioquinol intoxication result from medication errors
Agnes G van Velzen, Irma de Vries
University Medical Center Utrecht (UMCU), Utrecht, The Netherlands
206
Nicotinic acid overdose mimicking sepsis
Michael Hodgman, Christine Stork
Upstate Medical University, Syracuse, US
207
Parenteral iron overdose: the experience of the UK National Poisons Information Service
Leonard C Hawkins (1), John P Thompson (2), Euan A Sandilands (3), Sally M Bradberry (4), Simon HL Thomas (1)
(1)
Regional Drug and Therapeutics Centre, Newcastle upon Tyne, UK; (2) University Hospital Llandough, Cardiff,
UK; (3) Scottish Poisons Information Bureau, Edinburgh, UK; (4) City Hospital, Birmingham, UK
208
Poisonings with modified or prolonged release paracetamol tablets in Denmark
Anders Schultz, Tonny S Petersen, Kim P Dalhoff
Bispebjerg and Frederiksberg University Hospital, Copenhagen, Denmark
209
Pregabalin abuse in Munich: an increasing problem
Nicolas Zellner, Florian Eyer, Tobias Zellner
Klinikum rechts der Isar – School of Medicine, Technical University of Munich, Munich, Germany
210
Prolonged toxicity from amphetamine and quetiapine following overdose in a patient also taking cobicistat
Darren M Roberts, Jad Othman, Andrew H Dawson
Royal Prince Alfred Hospital, Sydney, Australia
211
Recurrent seizures following a paroxetine overdose in an infant
Marco Conte (1), Emanuela Masini (1), Francesco Gambassi (2), Alessandra Pistelli (2), Federico Melani (3), Elena Cravedi (3)
(1)
Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence,
Florence, Italy; (2) Medical Toxicology Unit and Regional Reference Center for Perinatal Toxicology, Azienda
Ospedaliero-Universitaria Careggi, Florence, Italy; (3) Pediatric Neurology Unit, A. Meyer Children’s Hospital
– University of Florence, Florence, Italy
52
POSTERS
THURSDAY 18 MAY 2017
Medication poisoning (including paracetamol and anti-convulsive drugs) (cont)
212
Severe and prolonged symptoms after intrathecal administration of gadobutrol (Gadovist®)
Anne Stürzebecher, Dagmar Prasa, Michael Deters, Helmut Hentschel
Poisons Information Centre Erfurt, Erfurt, Germany
213
Third degree heart block with accelerated junctional rhythm in verapamil overdose: a case series
Maxwell A Thompson (1), Nathan P Charlton (2), William F Rushton (1)
(1)
University of Alabama at Birmingham, Birmingham, US; (2) University of Virginia, Charlottesville, US
214
Thyrotoxicosis and anorectic pills: a case report
Michele S Milella (1), Susanna M Signoretti (1), Orietta Staltari (1), Davide Lonati (2), Maria Caterina Grassi (1)
(1)
Emergency Toxicology and Poison Control Centre Unit, Policlinico Umberto I and “Sapienza” University of
Rome, Rome, Italy; (2) Pavia Poison Control Centre and National Toxicology Information Centre, Toxicology
Unit, IRCCS Maugeri Foundation, Pavia, Italy
215
Unintentional ingestion of apixaban in a toddler
Gal Neuman (1), Alfred Cahana (1), Smadar Shilo (1), Yedidia Bentur (2)
(1)
Rambam Health Care Campus, Haifa, Israel; (2) Rambam Health Care Campus; The Rappaport Faculty of
Medicine, Technion-Israel Institute of Technology, Haifa, Israel
216
Validation analysis of poisoning severity scores in intentional self-poisoning cases
Timothy J Wiegand, Kenneth R Conner, Rachel Schult, Rachel Gorodetsky, Kimberly Kaukeinen
University of Rochester Medical Center, Rochester, US
217
Zopiclone poisoning and methemoglobinemia: French poison control centers data, 1999 to 2016
Lise Capaldo (1), Ingrid Blanc (2), Jacques Manel (2), Patricia Bernadet (2), Magali Labadie (2)
(1)
Poison Control Center, Bordeaux, France; (2) Poison Control Center, Paris, France
§ 218
Symptomatic elevation of anti-epileptic drug concentrations after addition of hemp oil extract to a
therapeutic regimen
Muhammad M Khalid (1), Elizabeth D Waring (2), David Vearrier (1), Rita McKeever (1), Michael I Greenberg (1)
(1)
Drexel University College of Medicine, Philadelphia, US; (2) Tulane University School of Medicine,
Philadelphia, US
219
Paracetamol-induced renal failure: an underestimated consequence of delayed managed overdoses
Bastien Domangé, Corinne Schmitt, Romain Torrents, Audrey Boulamery, Nicolas Simon, Luc De Haro
Marseille Poison Centre, Marseille, France
§ Shortlisted for Taylor & Francis best case study award
53
POSTERS
FRIDAY 19 MAY 2017
Animal poisoning
255
A case of voluntary exposure to the venom of the giant leaf frog (Phyllomedusa bicolor)
Lieven De Smedt (1), Martine Mostin (2), Peter De Paepe (1), Petra Van de Sijpe (2)
(1)
University Hospital Ghent, Ghent, Belgium; (2) Belgian Poison Control Centre, Brussels, Belgium
256
A study of verified spider bites in Slovenia
Tanja Varl (1), Damjan Grenc (1), Rok Kostanjšek (2), Miran Brvar (1)
(1)
University Medical Centre Ljubljana, Ljubljana, Slovenia; (2) University of Ljubljana, Ljubljana, Slovenia
257
Antidote treatment in viper envenomation in Italy: a comparison of two antivenoms
Davide Lonati (1), Azzurra Schicchi (1), Sarah Vecchio (1), Valeria M Petrolini (1), Eleonora Buscaglia (1), Giulia
Scaravaggi (1), Carlo A Locatelli (1), Alberto Malovini (2)
(1)
Pavia Poison Control Centre - National Toxicology Information Centre - Clinical and Experimental Lab,
Toxicology Unit, Maugeri Clinical and Scientific Institutes IRCCS, and University of Pavia, Pavia, Italy; (2)
Informatic and Systemistic Laboratory for Clinical Research, Maugeri Clinical and Scientific Institutes IRCCS,
Pavia, Italy
258
Local envenoming from Western hognose snake bites
Gillian Jackson (1), David Stewart (1), Caroline E McGrory (1), Sally M Bradberry (2), Simon HL Thomas (3), John P
Thompson (4), Michael Eddleston (1), Euan A Sandilands (1)
(1)
National Poisons Information Service (NPIS), Edinburgh, UK; (2) National Poisons Information Service
(NPIS), Birmingham, UK; (3) National Poisons Information Service (NPIS), Newcastle, UK; (4) National Poisons
Information Service (NPIS), Cardiff, UK
259
Pain management in erucism: outcome in 286 cases from the Campinas Poison Control Center
Maíra MB Pimenta (1), Tais F Galvao (1), Marcus T Silva (2), Eduardo M De Capitani (1), Stephen Hyslop (1), Fabio
Bucaretchi (1)
(1)
State University of Campinas, Campinas, Brazil; (2) UNISO, Sorocaba, Brazil
260
Safety of non-steroidal anti-inflammatory drugs in copperhead snakebite patients
Hoang X Pham, Michael E Mullins
Washington University School of Medicine, Saint Louis, US
261
Severe and fatal envenomation by wandering spiders (genus Phoneutria) in Brazil: a review of literature
reports
Fabio Bucaretchi (1), Eduardo M De Capitani (1), Marlene Zannin (2), Rogério Bertani (3), Stephen Hyslop (1)
(1)
Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas, Brazil; (2) Health Science
Center, Federal University of Santa Catarina (UFSC), Florianópolis, Brazil; (3) Butantan Institute, São Paulo,
Brazil
54
POSTERS
FRIDAY 19 MAY 2017
Animal poisoning (cont)
262
Successful treatment of persistent ciguatera with intravenous mannitol
Michael E Mullins, David B Liss, Anna M Arroyo-Plasencia, Evan S Schwarz
Washington University School of Medicine, Saint Louis, US
263
The EVEIT model as a means of improving the understanding of venom ophthalmia
Denise V Tambourgi (1), Marie Delafontaine (2), Claudia Panfil (3), Felix Spöler (4), Stefan Kray (4), François Burgher
(2)
, Laurence Mathieu (2), Joël Blomet (2), Norbert Schrage (3)
(1)
Butantan Institute, São Paulo, Brazil; (2) Prevor, Valmondois, France; (3) ACTO, Aachen, Germany; (4) RWTH
Aachen, Aachen, Germany
264
The need of a second antivenom dose after snake bites by Vipera berus
Mark Personne, Peter Hultén
Swedish Poisons Information Centre, Stockholm, Sweden
265
Thromboelastography in suspected Crotalus horridus horridus envenomation
William F Rushton (1), Michael Kurz (1), Justin Arnold (1), Nathan P Charlton (2)
(1)
University of Alabama at Birmingham, Birmingham, US; (2) University of Virginia, Charlottesville, US
§ 266
Venom-induced recurrent coagulopathy and hemorrhage in pregnancy
Elizabeth C Moore, Eleanor Oakley, Anne-Michelle Ruha
Banner-University Medical Center Phoenix, Phoenix, US
§ Shortlisted for Taylor & Francis best case study award
55
POSTERS
FRIDAY 19 MAY 2017
Animal poisoning (cont)
267
Viperidae snakebites and antivenoms in central and southeastern European and neighbouring countries of
Asia and Middle East
Vid Leban (1), Laima Gruzdyte (2), Marius Perminas (3), Gabija Mikulevičienė (4), Piotr M Kabata (5), Jacek Anand (5),
Wojciech Waldman (5), Ismail Afandiyev (6), Anna Krakowiak (7), Niko Bekjarovski (8), Blažena Caganova (9), Sergey
Zakharov (10), Hossein Hassanian-Moghaddam (11), Horatiu Moldovan (12), Galina N Bashinskaya (13), Alexander
Meister (14), Jasmina Jović-Stošič (15), Yury N Ostapenko (16), Barbara Nieradko-Iwanicka (17), Marine Grigoryan
(18)
, Ruth Kastanje (19), Csaba Pap (20), Vasil Atanasov (21), Margarita Gesheva (22), Anelia Loukova (22), Miroslava
Petkova (22), Emilia Kirova (22), Julia Radenkova-Saeva (22), Igor Stoianov (23), Yanko Iliev (24), Senzha Zlateva (25),
Evgenia Barzashka (26), Mojca Dobaja (1), Željka Babić (27), Igor Hrigorew (28), Miran Brvar (1)
(1)
University Medical Centre Ljubljana, Ljubljana, Slovenia; (2) Poison Information Bureau of the Health
Emergency Situations Centre of the Ministry of Health, Vilnius, Lithuania; (3) Lithuanian University of Health
Sciences Kauno Klinikos, Kaunas, Lithuania; (4) The Center of Toxicology of Republican Vilnius University
Hospital, Vilnius, Lithuania; (5) Clinical Toxicology Unit of Gdansk Medical University, Gdansk, Poland; (6) Center
of Clinical Toxicology MoH, Baku, Azerbaijan; (7) Nofer Institute of Occupational Medicine, Łódź, Poland; (8)
University Clinic for Toxicology, Skopje, The Former Yugoslav Republic of Macedonia; (9) National Toxicological
Information Centre, Bratislava, Slovakia; (10) Charles University and General University Hospital in Prague,
Prague, Czech Republic; (11) Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran;
(12)
University of Medicine and Pharmacy of Târgu Mureș, Târgu Mureș, Romania; (13) City Hospital Number One,
Astana, Kazakhstan; (14) Hospital Number One, Ust-Kamenogorsk, Kazakhstan; (15) Military Medical Academy,
Belgrade, Serbia; (16) Research and Applied Toxicology Center of Federal Medical Biological Agency, Moscow,
Russian Federation; (17) Medical University of Lublin, Lublin, Poland; (18) Yerevan State Medical University,
Yerevan, Armenia; (19) Estonian Poisons Information Centre, Tallinn, Estonia; (20) Department of Toxicology
Péterfy Hospital, Budapest, Hungary; (21) Bulgarian Society of Clinical Toxicology, Sofia, Bulgaria; (22) Toxicology
Clinic, UMHATEM “Pirogov”, Sofia, Bulgaria; (23) UMHAT “Stoyan Kirkovich”, Stara Zagora, Bulgaria; (24) UMHAT
“Sveti Georgi” Plovdiv, Plovdiv, Bulgaria; (25) Naval Military Medical Academy - Hospital Varna, Varna, Bulgaria;
(26)
UMHAT “Georgi Stranski”, Pleven, Bulgaria; (27) Institute for Medical Research and Occupational Health,
Zagreb, Croatia; (28) Ministry of Health Republic of Belarus, Minsk, Belarus
268
Two cases of tetrodotoxin poisoning from puffer fish consumption in Taiwan
Wan-Yin Kuo, Chien-Chin Hsu, Hung-Jung Lin
Chi-Mei Medical Center, Tainan, Taiwan
Epidemiology of poisoning
269
Accidental exposure to chemical compounds in Danish schools: a report from the Danish Poison Information
Center
Margrethe B Sköld, Paula EC Hammer, Nete B Hansen, Niels E Ebbehøj, Ellen B Pedersen
Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark
56
POSTERS
FRIDAY 19 MAY 2017
Epidemiology of poisoning (cont)
270
Acute phenobarbital poisoning: Moroccan Poison Control and Pharmacovigilance Centre data (2008-2014)
Narjis Badrane (1,2), Fatima Abadi (1), Naima Rhalem (1,2), Ahlam Meftah (1), Abdelmajid Soulaymani (2), Rachida
Soulaymani Bencheikh (1,3)
(1)
Poison Control and Pharmacovigilance Centre of Morocco; Rabat, Morocco; (2) Laboratory of Genetics and
Biometrics Ibn Tofail University, Kenitra, Morocco; (4) Faculty of Medicine and Pharmacy of Rabat, University
Mohammed V Souissi, Rabat, Morocco
272
Energy drink consumption patterns and knowledge of adverse effects amongst medical students, pharmacy
students, pharmacists and residents in Québec, Canada
Alexandre Doucet, Éric Villeneuve, Sophie Gosselin
McGill University, Montréal, Canada
273
Epidemiology of poisonings by psychoactive substances in Russia
Yury N Ostapenko (1), Igor Tiurin (2), Alexander Klyuev (2), Alexey Lodyagin (3), Valentin Sentsov (4), Elena Popova
(5)
, Alexander Sabaev (6), Alexander Shchupak (7), Vera Yukhno (7), Vladimir Kazachkov (1)
(1)
Research and Applied Toxicology Center of Medical and Biological Agency of Russian Federation, Moscow,
Russian Federation; (2) Moscow NV Sklifosovsky Research Institute of Emergency Aid, Moscow, Russian
Federation; (3) St Petersburg II Dzhanelidze Research Institute of Emergency Aid, St Petersburg, Russian
Federation; (4) Sverdlovsk Regional Psychiatric Hospital, Ekaterinburg, Russian Federation; (5) Krasnoyarsk
State Professor V.F. Voino-Yasenetsky Medical University, Krasnoyarsk, Russian Federation; (6) City Clinical
Hospital of Emergency Medical Aid No 1, Omsk, Russian Federation; (7) Far-Eastern State Medical University,
Khabarovsk, Russian Federation
274
Epidemiology of rattlesnake envenoming reported to an Arizona Poison Center
Nicholas B Hurst, Jessica N Reilly, Keith J Boesen, Farshad M Shirazi
Arizona Poison and Drug Information Center, Tucson, US
275
Fatal poisoning by pharmaceuticals and illicit drugs: comparison of cases reported to a Poisons Centre with
official death certificates
Mirjam Gessler (1), Cornelia Reichert (1), Christine Rauber-Lüthy (1), Christoph Junker (2), Hugo Kupferschmidt (1)
(1)
National Poisons Centre, Tox Info Suisse, Associated Institute of the University of Zurich, Zurich, Switzerland;
(2)
Federal Statistical Office, Neuchâtel, Switzerland
276
Fatalities due to acute intoxications from 2000 to 2015: a survey of the Poisons Information Centre Austria
Angelika Holzer, Ursula Schreiner, Sandra Hruby, Helmut Schiel, Tara Arif
Poisons Information Centre, Vienna, Austria
57
POSTERS
FRIDAY 19 MAY 2017
Epidemiology of poisoning (cont)
277
Liver injury in acute poisoning in children: specific issues of etiology and evolution
Coriolan E Ulmeanu (1), Dora Boghitoiu (1), Viorela Nitescu (1), Alina Grama (2), Bogdan Bulata (2), Aurel Bizo (2)
(1)
Pediatric Poisoning Centre Emergency Clinical Hospital for Children “Grigore Alexandrescu” Bucharest, Romania;
(2)
Pediatric Poisoning Centre Emergency Clinical Hospital for Children Cluj-Napoca, Cluj-Napoca, Romania
278
Paediatric and adolescent poisoning in the Hunter region of Australia
Michael A Downes, Caitlyn J Lovett, Geoffrey K Isbister
Calvary Mater Newcastle, Waratah, Australia
279
Characterizing benzodiazepine toxicities using the Toxicology Investigators Consortium (ToxIC) Registry
Kristin McCloskey, Ryan Surmaitis, David Goldberger, Rita McKeever
Drexel University College of Medicine, Philadelphia, US
Household products poisoning
281
Acute poisoning in children with concentrated laundry detergent capsules
Lylia A Kovalenko (1), Yury N Ostapenko (2), Galina N Sukhodolova (3), Alexander S Kovalchuk (1)
(1)
Children Poisoning Treatment Center, Moscow, Russian Federation; (2) Research and Applied Toxicology Center,
Moscow, Russian Federation; (3) The Chair of Reanimatology and Intensive Therapy, Moscow, Russian Federation
282
Characterization of endoscopic findings following ingestion of liquid laundry detergent packet products as
reported to US poison centers
William Banner (1), Ryan Lucas (2), Kate M Reynolds (2), Jody L Green (2)
(1)
Oklahoma Center for Poison and Drug Information, Oklahoma City, US; (2) Rocky Mountain Poison and Drug
Center, Denver, US
283
Circumstances of liquid laundry pod exposure: a prospective study based on calls to the French Poison
Control Centers
Sandra Sinno-Tellier (1), Fatoumata Rigaux-Barry (2), Laurie Cordier (3), Anne-Marie Patat (4)
(1)
French Agency for Food, Environmental and Occupational Health and Safety, Maisons-Alfort, France; (2)
Poison Control Centre of Nancy, University Hospital, Nancy, France; (3) Poison Control Centre of Toulouse,
University Hospital, Toulouse, France; (4) Poison Control Centre of Lyon, University Hospital, Lyon, France
284
Exposures to automatic dishwashing detergents examined by an Italian Poison Control Center
Anna Celentano, Fabrizio M Sesana, Beatrice Giliotti, Leonardo Molino, Joannhe Georgatos, Marcello
Ferruzzi, Franca Davanzo
Milan Poison Control Center, Milan, Italy
58
POSTERS
FRIDAY 19 MAY 2017
Epidemiology of poisoning (cont)
285
Ocular exposures to household detergents and cleaning products
Anna Celentano, Fabrizio M Sesana, Marcello Ferruzzi, Marco Morina, Valeria Dimasi, Franca Davanzo
Milan Poison Control Center, Milan, Italy
286
Paediatric poisonings from ethanol-based household products: a review of enquiries to the New Zealand
National Poisons Centre, 2003-2015
Mette G Goodin, Yvette C Millard
National Poisons Centre, University of Otago, Dunedin, New Zealand
Mechanisms of toxicity and basic research
287
Effects of insulin on statin-induced myopathy and insulin resistance
Gerda M Sanvee, Jamal Bouitbir, Stephan Krähenbühl
Clinical Pharmacology and Toxicology, University Hospital Basel, Basel, Switzerland
288
Electroencephalographic patterns of lithium poisoning: a study of the effect/concentration relationships in the rat
Anne-Sophie Hanak (1), Isabelle Malissin (2), Joel Poupon (3), Patricia Risède (1), Lucie Chevillard (1), Bruno Mégarbane (2)
(1)
INSERM UMRS-1144, Paris-Descartes & Paris-Diderot Universities, Paris, France; (2) Department of Medical
and Toxicological Critical Care, Lariboisière Hospital, Paris, France; (3) Laboratory of Toxicology, Lariboisière
Hospital, Paris, France
289
Mechanisms of cytotoxicity involved in metamizole-induced neutropenia
Deborah Rudin, Manuel Haschke, Stephan Krähenbühl
Clinical Pharmacology and Toxicology, University Hospital Basel, Basel, Switzerland
290
Neurobehavioral effects of lithium in the rat: an investigation of the effect/concentration relationships and
the contribution of the poisoning pattern
Anne-Sophie Hanak (1), Bruno Mégarbane (2,3), Lucie Chevillard (1), Rodolphe Lebeau (1), Patricia Risède (1), JeanLouis Laplanche (1), Nadia Benturquia (1)
(1)
Paris-Descartes & Paris-Diderot Universities, Paris, France; (2) INSERM UMRS-1144, Paris-Descartes & Paris-Diderot
Universities, Paris, France; (3) Department of Medical and Toxicological Critical Care, Lariboisière Hospital, Paris, France
291
Neuro-respiratory toxicity of baclofen in the rat: study of the concentration/effect relationships and role of
GABAergic receptors
Salma Tannous (1), Lucie Chevillard (1), Laurence Labat (1), Patricia Risède (1), Isabelle Malissin (2), Bruno Mégarbane (3,4)
(1)
Paris-Descartes & Paris-Diderot Universities, Paris, France; (2) Lariboisière Hospital, Paris, France; (3) INSERM
UMRS-1144, Paris-Descartes & Paris-Diderot Universities, Paris, France; (4) Department of Medical and
Toxicological Critical Care, Lariboisière Hospital, Paris, France
59
POSTERS
FRIDAY 19 MAY 2017
Mechanisms of toxicity and basic research (cont)
292
Tramadol-related neurotoxicity in the rat: contributions of the different neuromediators and effects of
potential antidotes
Hao Liang (1), Camille Lagard (1), Lucie Chevillard (1), Jacques Callebert (1), Patricia Risède (1), Bruno Mégarbane (2)
(1)
INSERM UMRS-1144, Paris-Descartes & Paris-Diderot Universities, Paris, France; (2) Department of Medical
and Toxicological Critical Care, Lariboisière Hospital, Paris, France
Plant and mushroom poisoning
293
A severe intoxication after ingestion of an infusion prepared with seeds bought over the Internet
Marco Morina, Anna Celentano, Paolo Severgnini, Ilaria Rebutti, Franca Davanzo, Maurizio Bissoli
Milan Poison Control Center, Milan, Italy
294
Aconite: rare but potentially serious poisoning
Francis Grossenbacher (1), Emmanuel Puskarczyk (2), Pierre Etienne Colot (3), Camille Richeval (4), Jean Michel
Gaulier (4), Helene Marty (5), Jacques Manel (2)
(1)
University Hospital Reims, Reims, France; (2) Poison Center Control Nancy, Nancy, France; (3) Emergency
Department, University Hospital Reims, Reims, France; (4) Toxicology and Pharmacology Department,
University of Lille, Lille, France; (5) Toxicology and Pharmacology Department Reims, Reims, France
295
Amanita phalloides poisoning in Slovenia, 1999- 2015
Andreja Vendramin, Marija Jamsek, Miran Brvar
University Medical Centre Ljubljana, Ljubljana, Slovenia
296
Anticholinergic toxicity associated with ingestion of water containing lupini bean extract
Kai Li (1), Xander Van Wijk (2), Sandra Hayashi (1), Craig Smollin (1)
(1)
California Poison Control Center, San Francisco, US; (2) University of California, San Francisco, US
297
Case report: a relaxing cup of poppy seed tea goes toxic
Ginger Rinner, Chelsea C White, Susan C Smolinske, Brandon J Warrick
University of New Mexico, Albuquerque, US
298
Cerbera manghas intoxication: a case report
Hon-Pheng Tam, Si-Chon Vong, Chien-Chin Hsu, Hung-Sheng Huang
Chi Mei Medical Center, Liouying, Taiwan
60
POSTERS
FRIDAY 19 MAY 2017
Plant and mushroom poisoning (cont)
299
Cerbera odollam poisoning in the western world: a potentially serious public health epidemic
Henry Fok (1), Punitha Victor (1), Sally M Bradberry (2), Michael Eddleston (1)
(1)
National Poisons Information Service, Edinburgh, UK; (2) National Poisons Information Service, Birmingham, UK
300
Classic appearances of aconitine intoxication: do physicians recognize the signs?
Hung-Sheng Huang (1), Chien-Chin Hsu (1), Chia-Hsien Huang (2)
(1)
Chi-Mei Medical Center, Tainan, Taiwan; (2) Ministry of Health and Welfare Pingtung Hospital, Pingtung
County, Taiwan
301
Colchicum autumnale or why autumn may be dangerous even if you are not depressed
Stefan Poechacker (1), Nina Grossmann (1), Julia Schuch (1), Fred Radunsky (1), Wolfgang Bicker (2)
(1)
Wilhelminenspital, Vienna, Austria; (2) FTC Forensic Toxicologic Laboratories, Vienna, Austria
302
Enquiries to a poisons information service concerning sycamore (Acer pseudoplatanus)
Alison M Good (1), Gillian Jackson (1), Caroline E McGrory (1), Simon HL Thomas (2), John P Thompson (3), Sally M
Bradberry (4), Euan A Sandilands (1)
(1)
NPIS Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, UK; (2) NPIS Newcastle, Regional Drug and
Therapeutics Centre, Newcastle upon Tyne, UK; (3) NPIS Cardiff, University Hospital Llandough, Cardiff, UK; (4)
NPIS Birmingham, City Hospital, Birmingham, UK
303
Erycibe henryi-induced acute cholinergic syndrome
Han-Wei Mu, Dong-Zong Hung
Division of Toxicology, China Medical University Hospital, Taichung, Taiwan
304
Gastrointestinal toxicity and acute kidney injury following ingestion of suspected Amanita ochrophylla
Darren M Roberts (1), Colin B Page (2)
(1)
Sydney Children’s Hospital Network, Sydney, Australia; (2) Princess Alexandra Hospital, Brisbane, Australia
305
Suicide attempt by infusion of rotenone-containing plant extracts: a case report from French Polynesia
Romain Torrents, Corinne Schmitt, Mathieu Glaizal, Bastien Domange, Katarina Moenikes, Susanna Davoust,
Audrey Boulamery, Luc De Haro, Nicolas Simon
APHM, Hôpitaux Sud, Marseille, France
61
POSTERS
FRIDAY 19 MAY 2017
Poisoning management (including pre-hospital management)
306
Methanol poisoning inadvertently treated with vodka via intravenous administration
Elizabeth C Moore, Will Heise, Maureen Roland, Belinda Sayers, Daniel E Brooks
Banner Poison and Drug Information Center, Phoenix, US
307
Acute beta-blocker overdose management: factors associated with cardiovascular mortality in a Caribbean
intensive care unit
Dabor Resiere (1), Ruddy Valentino (1), Cyrille Charbatier (1), Joceyn Inamo (1), Bruno Megarbane (2), Hossein Mehdaoui (1)
(1)
University Hospital of Martinique, Fort-de-France, France; (2) Lariboisière Hospital, Paris, France
308
Advances in a knowledge-based decision support system for the diagnosis of human toxic exposures
Joel D Schipper (1), Jay L Schauben (2), Douglas D Dankel II (3)
(1)
Embry-Riddle Aeronautical University, Prescott, US; (2) Florida/USVI Poison Information Center; University
of Florida Health Science Center, Jacksonville, US; (3) University of Florida, Gainesville, US
309
An outbreak of foodborne botulism due to stuffed pizza with olives
Francesco Gambassi (1), Angelo Rotulo (1), Fabrizio Anniballi (2), Bruna Auricchio (2), Dario De Medici (2), Davide
Lonati (3), Carlo Locatelli (3), Irene Campolmi (4), Francesca Rinaldi (4), Michele Spinicci (4), Emanuela Masini (5)
(1)
Toxicology Unit and Poison Control Center, AOU Careggi, Florence, Italy; (2) National Reference Center for
Botulism, Department of Veterinary Public Health and Food Safety, Istituto Superiore di Sanità, Rome, Italy; (3)
Pavia Poison Centre and National Toxicology Information Centre, IRCCS Maugeri Foundation Clinical Institute and
University of Pavia, Pavia, Italy; (4) Infectious and Tropical Disease Unit, AOU Careggi, Florence, Italy; (5) Toxicology
Unit and Poison Control Center, AOU Careggi; Department of NEUROFARBA, University of Florence, Florence, Italy
310
Appropriateness of assessment of acute recreational drug toxicity in onsite nightclub medical facilities
Matthew S Blundell, Mark Haden, Paul I Dargan, John RH Archer, David M Wood
Guy’s and St. Thomas’ NHS Foundation Trust, London, UK
311
Avoidable management errors in acute salicylate poisoning
Michael E Mullins
Washington University School of Medicine, Saint Louis, US
312
Dexmedetomidine for alcohol withdrawal: looks can be deceiving
Morgan AA Riggan (1), Mark K Su (2), Robert S Hoffman (1)
(1)
NYU School of Medicine, New York, US; (2) New York City Poison Control Center, New York, US
313
Does a patient with severe aluminum phosphide intoxication pose a danger to healthcare providers?
Marianne EC Leenders, Claudine C Hunault, Irma de Vries
University Medical Center Utrecht (UMCU), Utrecht, The Netherlands
62
POSTERS
FRIDAY 19 MAY 2017
Poisoning management (including pre-hospital management) (cont)
314
Effect of extracorporeal treatments in a patient with prolonged phenytoin toxicity
Darren M Roberts (1), Tina Xu (2), Colin B Page (3)
(1)
Royal Prince Alfred Hospital, Sydney, Australia; (2) The Canberra Hospital, Canberra, Australia;
Alexandra Hospital, Brisbane, Australia
(3)
Princess
315
Glucose-6-phosphate hydrogenase (G6DP) deficiency induced by 6-aminonicotinamide in hepatocytes: a
protective factor in phosphine exposure
Nasim Zamani, Maryam Paeezi, Hossein Hassanian-Moghaddam, Shahin Shadnia, Jalal Pourahmad
Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran
316
Hyperbaric treatment for hydrogen peroxide poisoning associated with portal venous gas and neurological
symptoms: a case report
Barak Levit (1), Yael Lurie (1), Igor Markovich (1), Anna Bloom Krasik (1), Ronen Bar (2), Yedidia Bentur (1)
(1)
Rambam Health Care Campus, Haifa, Israel; (2) Israel Naval Medical Institute, Haifa, Israel
317
Management of a mixed overdose in the prehospital setting: a case report
Eric Villeneuve (1), Marie-Soleil Delisle (1), Josh J Wang (2), Sophie Gosselin (1)
(1)
McGill University Health Centre, Montréal, Canada; (2) McGill Faculty of Medicine, Montréal, Canada
318
Metformin poisoning in the intensive care unit: a clinical, prognostic and pharmacokinetic study
Nicolas Péron (1), Bruno Mégarbane (1-3), Xavier Declèves (2), Christophe Bardin (2), Lucie Chevillard (3), Isabelle
Malissin (1), Nicolas Deye (1), Sébastian Voicu (1)
(1)
Department of Medical and Toxicological Critical Care, Lariboisière Hospital, Paris, France; (2) Laboratory
of Toxicology, Cochin Hospital, Paris, France; (3) INSERM UMRS-1144, Paris Descartes & Paris-Diderot
Universities, Paris, France
319
Need hemodialysis? Only during business hours!
Mark K Su (1), Robert S Hoffman (2), Ian Julie (3), Pui Y Chan (4), Sung W Lim (4), Sage Wiener (5)
(1)
New York City Poison Control Center, New York, US; (2) New York University, New York, US; (3) UC Davis,
Sacramento, US; (4) New York City DOHMH, New York, US; (5) SUNY Downstate Medical Center, Brooklyn, US
320
Outcome of intoxicated patients admitted to the Intensive Care Unit (TOXIC study)
Irma S Van den Hengel-Koot (1), Saskia J Rietjens (1), Douwe Dekker (2), Karin AH Kaasjager (2), Irma de Vries (1),
Dylan W De Lange (1,3), Laura Hondebrink (1)
(1)
Dutch Poisons Information Center (DPIC), University Medical Center Utrecht (UMCU), Utrecht, The
Netherlands; (2) Department of Internal Medicine, UMCU, Utrecht, The Netherlands; (3) Department of
Intensive Care Medicine, University Medical Center Utrecht (UMCU), Utrecht, The Netherlands
63
POSTERS
FRIDAY 19 MAY 2017
Poisoning management (including pre-hospital management) (cont)
321
Poisons information at the frontline: use of the TOXBASE app by UK ambulance service staff in the pre-hospital setting
David J Lupton (1), Lindsay D Gordon (1), Gillian Jackson (1), Sally M Bradberry (2), John P Thompson (3), Simon HL
Thomas (4), Euan A Sandilands (1)
(1)
NPIS Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, UK; (2) NPIS Birmingham, City Hospital,
Birmingham, UK; (3) NPIS Cardiff, University Hospital Llandough, Cardiff, UK; (4) NPIS Newcastle Regional Drug
and Therapeutics Centre, Newcastle upon Tyne, UK
322
Protective effect of erythropoietin in visual disturbances due to methanol poisoning: a preliminary report
Nasim Zamani, Hossein Hassanian-Moghaddam, Shahin Shadnia
Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran
323
Recalled to life: prolonged action of pancuronium in a neonate suggesting death reversed with neostigmine
Sian CD Harbon, John P Thompson, James M Coulson
UK National Poisons Information Service, Cardiff, UK
324
Suicide attempt with acetonitrile treated with sodium thiosulfate: a case report
Eduardo M De Capitani, Carla F Borrasca-Fernandes, Maíra Branco, Rafael Lanaro, José Luis Costa, Sueli M
Mello, Helena Nóbrega, Fábio Bucaretchi
State University of Campinas, Campinas, Brazil
325
Update after 20 years of take home naloxone programs
Thomas Martin
Texas Tech University, Amarillo, US
326
When an international vacation almost kills your teenager: case report of severe Bothrops asper
envenomation of an American teenager while in Belize with common and not so common manifestations
Benjamin N Abo (1), Spencer Johnson (1), Scott R Mullin (2)
(1)
University of Florida, Gainesville, US; (2) Miami Dade Fire Rescue, Miami, US
327
When new therapies fail and old therapies are forgotten: a case of a late nortriptyline death with failed
lipid emulsion therapy Morgan AA Riggan, Rana Biary, Robert S Hoffman, Daniel M Lugassy
NYU School of Medicine, New York, US
192
Acute tenofovir overdose causes benign symptoms: a case series
Lovisa Östberg, Jonas Höjer
Swedish Poisons Information Centre, Stockholm, Sweden
64
CONGRESS SUPPORTERS AND SPONSORS
The EAPCCT gratefully acknowledges support from the following
organisations:
The member companies of
the KGF (Kontaktgruppe für
Forschungsfragen), BASF,
F. Hoffmann-La Roche AG,
Novartis and Syngenta
Kanton Basel-Stadt
Federal Office of Public
Health, Switzerland
Fundación Española de
Toxicología Clínica
c
eto
f
fundación española de toxicología clínica
SCAHT - Swiss Centre for
Applied Human Toxicology
65
CONGRESS SUPPORTERS AND SPONSORS
The EAPCCT gratefully acknowledges support from the following
exhibitors:
Flynn Pharma
Laboratoires SERB
Prevor
Taylor & Francis Group
Truven Health Analytics. IBM
Watson Health
66
Congress of the European Association of
Poisons Centres and Clinical Toxicologists
9:00-18:00
8:00-9:00
Time
Registration (open all day)
Room Montreal
TUESDAY 16 MAY 2017
PRE-CONGRESS
Toxicology of migration
9:45-10:30
Evening
16:15-17:00
15:45-16:15
14:00-15:45
12:30-14:00
11:10-12:30
Antidotes: something old,
something new, something
borrowed, something Blue
Antidotes: something old,
something new, something
borrowed, something Blue
(cont)
Oral session:
Poisoning outbreaks
Welcome Reception at Volkshaus Basel
Oral session:
Epidemiology of poisoning
Co ee & E-posters afternoon
Controversies in pesticide
toxicology
Antidotes: something old,
something new, something
borrowed, something Blue
(cont)
Lunch & posters
Short orals session (1)
Toxicology of migration
(cont)
Co ee & E-posters morning
Welcome
Plenary Lecture
10:30-11:10
Room Singapore
Registration (open all day)
Room Montreal
WEDNESDAY 17 MAY 2107
MAIN CONGRESS
8:55-9:00
9:00-9:45
7:30-9:00
Time
PROGRAMME AT A GLANCE
EAPCCT 2017
37th
Toxicological analysis and contribu on to
diagnosis and pa ent management in
clinical toxicology
Room Singapore
Toxicology of anticonvulsant drugs
Short orals session (2)
Toxicology of anticonvulsant drugs (cont)
Toxicosurveillance (including
poison control centre
activities)
Oral sessions:
Experimental and Applied
Research
Round table on social media
General Assembly
17:00-18:30
Oral session:
Novel Psychoactive
Substances
Co ee & E-posters afternoon
Short oral presentations:
Social Media
The Virtual Toxicologist:
Leveraging Social Media For
Toxicology Education,
Outreach and Research
Lunch & posters
Paracetamol poisoning: new
insights
Co ee & E-posters morning
Pro/Con Debate:
Paracetamol poisoning
Louis Roche Lecture
Registration (open all day)
Room Montreal
THURSDAY 18 MAY 2017
MAIN CONGRESS
16:15-16:45
16:15-17:00 in
Singapore
15:45-16:15
14:00-15:45
12:30-14:00
11:10-12:30
10:30-11:10
9:45-10:30
8:45-9:45
8:00-8:45
Time
Evening
16:15-17:00
15:45-16:15
14:00-15:45
12:30-14:00
11:10-12:30
10:30-11:10
8:45-10:30
8:15-8:45
Time
Room Singapore
Oral session:
Education and outreach
Short orals session (3)
Special session:
Polonium-210 poisoning: a
first-hand account
Best paper session
Oral session:
Natural toxins
Conference Dinner at Safranzunft Basel
Pre-hospital management of
poisonings (cont)
Co ee & E-posters afternoon
Pre-hospital management of
poisonings
Oral session:
Education and outreach
(cont)
Lunch & posters
Biomarkers, clinical
toxicology and translational
medicine
(APAMT Symposium)
Co ee & E-posters morning
Young Investigator Award
Registration (open all day)
Room Montreal
FRIDAY 19 MAY 2017
MAIN CONGRESS
www.eapcct.org
#eapcct2017