Download Assignment Due Date: Introduction

Mitosis Web Quest
Name: _____________________________________
MV Biology
Assignment Due Date: ________________
Introduction:
Why can’t organisms just be one giant cell? Diffusion cannot occur quickly and efficiently if the distances
involved become too large. Wastes would collect inside the cell and poison it. Nutrients could not reach
organelles in time, so cells would die. Information overload would occur. DNA does not make copies as a cell
grows – what it starts with is all that it has. There must be enough DNA blueprint to allow for protein
production. For these reasons, the cells of living organisms must regularly divide. This process is called CELL
DIVISION.
Follow the directions verbatim and in order to complete this assignment. There are FOUR aspects:
1. Mitosis Microviewer Lab (completed in class) – 15 Points
2. The Web Quest (completed at home and in class) – 25 Points
3. The Cell Cycle Book (completed in class) – 10 Points
4. Poster Project on Cancer (completed at home) – 50 Points
The web sites may be posted on your teacher’s web page for easy access – so that you don’t have to type in long
URLs. The goal of this activity is to enhance your knowledge of the cell cycle – including an in-depth
understanding of the following:
1. Limits to Cell Size & Reasons for Cell Division
2. Stages of the Cell Cycle
3. Appearance of Chromosomes During the Cell Cycle
4. Uncontrolled Cell Cycle (Cancer)
Overview/Introduction Procedure
1. The first step is to preview an animation that introduces you to the cell cycle. This animation can be
accessed via the following web link: http://highered.mcgrawhill.com/sites/0072495855/student_view0/chapter2/animation__how_the_cell_cycle_works.html
2. The second step is to preview an animation that introduces you to mitosis (nuclear division). This animation
can be accessed via the following web link: http://highered.mcgrawhill.com/sites/0072495855/student_view0/chapter2/animation__mitosis_and_cytokinesis.html
Procedure #1
Log on to the following web page:
http://www.quia.com/servlets/quia.activities.common.ActivityPlayer?AP_rand=1538401416&AP_activityType
=12&AP_urlId=3371&AP_conti
1. Read the instructions on the web page and complete the activity.
2. When you have successfully completed the activity, you will see “YOU WIN” and you can see the hidden
picture. PRINT this page out to turn in with your assignment. It DOES NOT have to be in color.
Mitosis Web Quest
MV Biology
Procedure #2
Log on to the following web page: http://www.biology.arizona.edu/cell_bio/activities/cell_cycle/cell_cycle.html
1. Read the introduction, then click “next” at the bottom of the page.
2. You will have 36 cells to classify. Follow the given directions on the web page.
3. When you are finished, record your information in the data chart below:
Interphase
Prophase
Metaphase
Anaphase
Telophase
Total
Number of
Cells
Percent of
Cells Seen
HINT: To calculate % - take the number of cells seen in each phase and divide by total number of cells. Then multiply by 100.
Procedure #3
Log on to the following web page: http://www.cellsalive.com/
1. On the left side of the screen is a navigator bar. Click on the “Mitosis” link.
2. Read the text on this page and view the animation. You can make the video slow down by clicking step by
step through the phases. Watch the video CAREFULLY - Answer the following questions:
a. List and briefly describe the stages of mitosis:
b. In which stage does the following occur?
i. chromatin condenses into chromosomes:________________________
ii. chromosomes align in center of cell:_________________________
iii. longest part of the cell cycle: _______________________________
iv. nuclear envelope breaks down: _____________________________
v. cell is cleaved into two daughter cells: _______________________
vi. daughter chromosomes arrive at polls: ______________________
c. The colored chromosomes represent chromatids. Why are there two of each color?
_________________________________________________________________________________
d. How many chromosomes are visible at the beginning of mitosis? ____________________________
e. How many are in each cell at the end of mitosis? _________________________________________
f. The little green T shaped items on the cell are centrioles. What happens to the centrioles during
mitosis? _________________________________________________________________________
Mitosis Web Quest
MV Biology
Procedure #4
Log on to the following web page: http://www.quia.com/rr/89527.html
1. Press “Start” on the rags to riches game.
2. Answer the questions to earn $$.
3. You must make at least $250,000.00. Once you pass this point, PRINT out this page to turn in with your
assignment.
4. Be CAREFUL…if you answer incorrectly, you will have to start over!
Procedure #5
Log on to the following web page: http://plaza.ufl.edu/alallen/pgl/modules/rio/stingarees/module/what.html
1. Name the reasons shown for cell division:
2. There are several parts of the cell involved in cell division. Click on the parts shown at the following web
page and read what they do: http://plaza.ufl.edu/alallen/pgl/modules/rio/stingarees/module/index.html
a. What do the centrioles do for the cell?
3. The following site explains the function of the spindle fibers:
http://www.nature.com/scitable/definition/spindle-fibers-304
a. Define and draw a spindle fiber.
Mitosis Web Quest
MV Biology
Procedure #6
Now it’s time for a quick review. Watch the following animation:
http://www.sumanasinc.com/webcontent/animations/content/mitosis.html
1. Read the Introduction.
2. Click “Narrated”.
3. Click on the “Show Text” icon at the bottom corner of the animation – it is located between the house and
the Q.
4. Click the arrow to play the animation.
5. Read the Conclusion.
6. You may go back to the beginning and choose the “Step Through” version to enhance your
understanding…this version allows you to control the speed of the animation.
Procedure #7
Now that you have reviewed all of the web animations, you are ready to create your book on the Cell Cycle and
Mitosis. Complete the following steps in order…you will turn in your book with this assignment.
1. Obtain 2 blank sheets of paper & colored pencils. You will also need your textbook.
2. With the paper stacked on top of each other, fold the paper from left to right down the middle of the page
(like a hamburger).
3. PAGE 1: Create a book cover that includes a title for your book and the name of the author of the book
EACH OF THE FOLLOWING PAGES SHOULD HAVE A HEADER/TITLE AND PAGE NUMBER.
YOUR PAGES SHOULD BE COLORFUL AND CREATIVE AND ANY DEFINITIONS or
EXPLANATIONS SHOULD BE EASILY UNDERSTOOD – I.E. DO NOT COPY STRAIGHT FROM
THE BOOK – REWORD FOR UNDERSTANDING!
4. PAGE 2: Draw and describe a chromosome – use pg. 139 in your textbook for help - be sure to include a
description of what chromosomes are made of!
5. PAGE 3: Using page 134 in your textbook, draw and label a circular chart that shows the events of the cell
cycle.
6. PAGE 4: Describe the 3 stages of Interphase AND what occurs in each phase (text page 135).
7. PAGE 5: Define Mitosis - list the 4 phases of Mitosis (text page 140).
8. PAGE 6: Using page 141 in your textbook, draw AND describe the phases of Mitosis (including
Cytokinesis). Your drawings should be labeled, detailed, and in color with a written description to describe
each phase!
9. PAGE 7: Define Cytokinesis - include a drawing of what this looks like (text page 140 & 141).
10. PAGE 8: Describe uncontrolled cell growth (cancer) – include a drawing of what this looks like (text page
146).
11. Staple your book pages together and submit with your project packet.
Procedure #8
Now that you have completed your Cell Cycle book, you are ready to review the Mitosis Microviewer Lab. Be
sure this assignment is completed…you will turn in your lab with the project packet.
Mitosis Web Quest
MV Biology
Procedure #9
It is now time to research uncontrolled cell growth and cancer. You will submit a tri-fold poster that
summarizes your research. The requirements for the poster are below:
Cell Cycle Checkpoints

G1

G2

M

Visuals for Each

Growth Factors

Apoptosis
Cancer (Choose a Type to Research)
Requirements Below
Tumors
(benign v. metastasized)
Treatment Options
Prevention
Left Panel:
1. Describe the cell cycle checkpoints that help control cellular division (G1, G2, and M). Discuss the purpose
of each checkpoint and include a visual of each checkpoint.
 Include a discussion of both external and internal factors that help regulate the cell cycle.
 Include a discussion of apoptosis and its role in helping to kill destructive cancer cells (a visual
should be included here).
Middle Panel:
1. Choose a type of cancer to research. For your type, include the following:
 Describe the cancer and the molecular basis of the cancer (i.e. what specifically causes the cancer).
 Discuss the symptoms of the cancer. Is it aggressive or slow growing? Etc.
 Include a visual.
 Discuss risk factors associated with the cancer. Is there a gender more at risk? An ethnicity? Etc.
Are there activities that put people at risk for this type of cancer? Etc.
 You should be thorough here and include as many points about your cancer as you can find that will
help educate your peers.
Right Panel:
1. Discuss tumors and the difference between a benign and metastasized tumor.
2. Include a visual.
3. Discuss the various treatment options for your chosen cancer type and include the risk factors involved in
each treatment option. How successful are these treatment options? Etc.
4. Discuss any preventative measures that can be taken to reduce risk for your chosen cancer type.