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Enhanced Recovery After Surgery “The immediate challenge to improving the quality of surgical care is not discovering new knowledge, but rather how to integrate what we already know into practice.” Urbach & Baxter, 2005 LAUREN NORTHEY, VASCULAR CNC – MARCH 2015 What is ERAS? ERAS - PNAQ Colorectal Surgery Preoperative Counselling Medical Optimisation Carbohydrate Drinks & Fasting Bowel Preparation Intraoperative Anaesthetic & Analgesia Fluid Management Postoperative Nutrition Mobilisation Nambour General Hospital What is ERAS? An innovative approach to recovery after surgery which emphasises the patients’ optimal return to normal function A series of evidence-based interventions covering the entire perioperative period and using a standardised pathway of care Pathways aim to reduce surgical stress, maintain postoperative physiological function and enhance mobilisation after surgery resulting in Reduced rates of morbidity Faster recovery Decreased length of stay in hospital ERAS in Colorectal Surgery Early Mobilisation Patient Counselling No Bowel Preparation Carbohydrate Drinks & Minimal Fasting Early Post-op Oral Nutrition No Premedication Early Removal of Catheters ERAS Prevention of PONV No Nasogastric Tubes Epidural Anaesthesia Normothermia Short-acting Anaesthetics Avoidance of Fluid Overload Non-opioid Analgesics No Drains Short Incisions / Lap Technique Preoperative Counselling Intensive preoperative patient information facilitates recovery, improves post-operative self care and has been shown to reduce anxiety and pain1,2 Counselling should emphasise the importance of a patient’s role in their own recovery. Patients should be given goals to meet during their post-operative period, for example Tolerating diet and fluids Sitting out of bed Mobilising several times a day Social aspects that may delay discharge should be identified and criteria for discharge should be explained, this may include Oral analgesia adequately controlling pain Satisfactory wound healing Independently performing activities of daily living or return to pre-surgery function Preoperative Optimisation Detecting and modifying comorbidities before major surgery results in a reduction in morbidity and in the need for more complex supportive care, such as intensive care3 Cardiovascular risk Pulmonary risk Anaemia Nutrition and exercise Obesity Diabetes Smoking and alcohol intake Carbohydrate Drinks & Fasting Fast from solid food for six hours and encourage clear fluids up until two hours before surgery Preoperative carbohydrate rich drinks reduce thirst, hunger and anxiety4 Reduces postoperative insulin resistance4 Unpleasant, can be stressful for the patient Bowel Preparation Increased rates of pre-operative admission to hospital solely for bowel preparation Increased risk for patients with renal dysfunction and the elderly – can cause large fluid shifts, dehydration, electrolyte imbalance and acute renal failure. Cao, Li & Li (2011): Meta analysis for secondary outcomes including 14 trials shows no significant effect whether patients had mechanical bowel preparation before surgery5 Bowel Preparation Cao, Li & Li (2011): Meta analysis for anastomotic leak including 14 trials shows no significant effect whether patients had mechanical bowel preparation before surgery5 Anaesthetic & Surgery Avoid preoperative sedative medications as they can delay post operative mobility and oral intake Recommended use of short acting induction agents and short acting opioids to allow for rapid awakening Multimodal approach to PONV with two or more antiemetic agents given as prophylaxis intraoperatively Avoidance of NGTs, or if used to be removed before reversal of anaesthetic Maintain normothermia >36°C prevents wound infection improves patient pain scores reduces bleeding reduces incidence of cardiac complications 7 Analgesia Thoracic epidural anaesthetic is recommended for open surgery Laparoscopic surgeries are performed with regional/TAP blocks to reduce postoperative opioid requirement Patient controlled analgesia (PCA) is provided postoperatively with an aim to remove the PCA by day two at the latest Postoperative analgesia should always be multimodal Paracetamol NSAIDs (depending on surgeon preference) Fluid Management Traditionally, patients were given bowel preparation and fasted for prolonged periods of time before their surgery – potentially leaving them dehydrated and with electrolyte imbalances ERAS patients are better conditioned for surgery as they’re not given bowel prep and are encouraged to continue clear fluids up until two hours before surgery Aim to maintain normovolaemia through the use of vasopressors intraoperatively rather than by multiple fluid boluses Hypovolaemia can lead to hypoperfusion of vital organs Fluid overload can lead to bowel oedema and delay return of gastrointestinal function Fluid shifts should be minimised where possible – by avoiding bowel preparation, encouraging oral hydration up to two hours before surgery and minimising bowel handling and blood loss during surgery Intravenous fluids should be ceased as soon as the patient is tolerating oral hydration. Target for oral hydration should be 800mLs on day of surgery. Nutrition Oral nutritional supplements commence two hours post surgery and continue each day until discharge Achieves target intakes of energy and protein during early postoperative recovery Early enteral or oral feeding reduces risk of infection and length of stay in hospital and is not associated with risk of anastomotic dehiscence6 However, early oral feeding does increase the risk of vomiting and patients should be assessed for PONV Mobilisation There is more evidence detailing the detriment of prolonged bed rest than the benefits of early mobilisation Combining forced mobilisation and nutritional support in the early postoperative phase has been shown to increase muscle strength7 Prolonged bed rest has been associated with an increase in chest infections, muscle weakness and an increase in length of stay in hospital Failure to mobilise on day one has been associated with longer length of hospital stay, likely due to other factors such as inadequate pain control, preexisting comorbidities and patient motivation Nambour General Hospital Questions? References 1 2 3 4 5 6 7 Disbrow EQ, Bennett HL, Owings JT. Effect of preoperative suggestion on postoperative gastrointestinal motility. West J Med. 1993;153(5):438-92 Blay N, Donoghue J. The effect of pre-admission education on domiciliary recovery following laparoscopic cholecystectomy. Aust J Adv Nurs. 2005;22(4):14-9 Halaszynski TM, Juda R, Silverman DG. Optimizing postoperative outcomes with efficient preoperative assessment and management. Crit Care Med. 2004;32(4):S76-86 Soop M, Nygren J, Myrenfors P, Thorell A, Ljungqvist O. Preoperative oral carbohydrate treatment attenuates immediate postoperative insulin resistance. Am J Physiol Metabol 2001;280(4):E576-83 Cao F, Li J, Li F. Mechanical bowel preparation for elective colorectal surgery: updated systematic review and meta-analysis. Int J Colorectal Dis. 2012;27:803-810 Lewis SJ, Andersen HK, Thomas S. Early enteral nutrition within 24h of intestinal surgery versus later commencement of feeding: a systematic review and meta-analysis. J Gastrointest Surg. 2009;13(3):569-575 Gustafsson UO, Scott MJ, Schwenk W, Demartines N, Roulin D, Francis N, McNaught CE, MacFie J, Liberman AS, Soop M, Hill A, Kennedy RH, Lobo DN, Fearon K, Ljungqvist, O. Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations. World J Surg. 2013;13:259-284