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Physiological Psychology 830:484 Barry R. Komisaruk, Ph.D. Email: [email protected] Professor II Department of Psychology Board of Governors Distinguished Service Professor Associate Dean of the Graduate School Rutgers, The State University of New Jersey and Dept. Radiology University of Medicine and Dentistry of New Jersey Newark, NJ, U.S.A. PITUITARY GLAND HORMONES Posterior Pituitary Oxytocin (= Pitocin) Vasopressin (=AntiDiuretic Hormone=ADH) Anterior Pituitary Thyroid Stimulating Hormone (TSH) AdrenoCorticoTropic Hormone (ACTH) Follicle Stimulating Hormone (FSH) Luteinizing Hormone (LH) (=Interstitial Cell Stimulating Hormone = ICSH) Prolactin(=LuteoTropic Hormone = LTH) Growth Hormone (=SomatoTropic Hormone = STH) Melanocyte Stimulating Hormone (MSH) ANTIDEPRESSANTS: Increase levels of serotonin in synapses. However, inhibit sexual response: •SSRI (Selective Serotonin Reuptake Inhibitor) Stimulate Serotonin 2a receptors…..Inhibit sexual response Fluoxetine (Prozac) Paroxetine (Paxil) Sertraline (Zoloft) •SARI (Serotonin 2 Antagonist and Reuptake Inhibitor) Block Serotonin 2 receptors…..Stimulate sexual response Trazodone (Desyrel) Nefazodone (Serzone) •Agonist of Serotonin 1a receptor: Buspirone (BuSpar) no sexual response interference •Catecholaminergic: Buproprion (Wellbutrin) Increases NE and DA; no Serotonin action.. Increases orgasm & ejac Reboxetine (Edronax) Increases NE; no Serotonin action •Herbal: St. Johns Wort Mechanism unknown; no sexual side effects