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Increasing the Cost-Effectiveness of Depression Treatment with Collaborative Care – 03/2016 1 Meadows Mental Health Policy Institute Increasing the Cost-Effectiveness of Depression Treatment with Collaborative Care – March 2016 DepressioncostsU.S.employersapproximately$187.8billionayear.1,2Thistotalincludes annualcostsof$134billioninhealthcare(healthandmentalhealthcombined),$20.9billionin absenteeism,and$32.9billioninlostproductivity.Despitethegrowingbodyofresearch demonstratingtheeffectivenessofdepressiontreatment,manyemployeesandtheir dependentsdonotgetthetreatmenttheyneed,unnecessarilyraisingemployers’healthcare andproductivitycosts.Implementing“CollaborativeCare3”interventionscanaddressthis problembycorrectinghealthcaredeliverysystemflawsthatpreventindividualsfromaccessing andsuccessfullycompletingevidence-baseddepressiontreatment.Buttraditionalemployee benefitsdonotcoverCollaborativeCareinterventionseventhoughtheycanbecost-effective. Toensureemployeesandtheirdependentsreceiveeffectivedepressiontreatment,and employersexperiencetheassociatedcostsavings,innovationinbenefitdesignanddelivery systemstoincludeCollaborativeCareinterventionsisanecessarynextstep. DepressionIsReal IntheUnitedStates,oneinfiveadults(20%)willexperienceaclinicallysignificantformof depressionintheirlifetime.4About7.5%oftheUSworkforcehasdepressioninanyyear.5 Depressionisaseriousillnessthatcanimpactanyone,includingthemostproductiveemployee andtheyoung,rising-starexecutive.AstheNationalInstituteofMentalHealthnotes, “Depressiveillnessesaredisordersofthebrain.Longstandingtheoriesaboutdepression suggestthatimportantneurotransmitters—chemicalsthatbraincellsusetocommunicate—are 1 Mrazek,D.A.,Hornberger,J.C.,Altar,C.A.&Degtiar,I.(2014).Areviewoftheclinical,economicandsocietal burdenoftreatment-resistantdepression1996-2013.PsychiatricServices,65(8). 2 Mrazeketal’scostanalysisincludedfouremployer/privatepayerclaimsdatabasesandoneMedicareclaims database.Estimateswerebasedona12-monthprevalenceofdepressionin16,000,000adults;thepercentageof peoplewithtreatmentresistantdepressionwas12%(conservatively);averagedirecthealthcarecostsforpeople withtreatmentresistantdepressionwere$13,196annually;averagedirecthealthcarecostsforpeoplewith treatmentresponsivedepressionwas$7,715;averageproductivity-relatedcostswere$6,924and$2,876, respectively. 3 CollaborativeCareisatypeofintegratedcareinwhichtrainedprimarycareprovidersandembeddedbehavioral healthprofessionalsprovideevidence-basedtreatments,supportedbyregularpsychiatriccaseconsultationand treatmentadjustmentforpatientswhoarenotimprovingasexpected.AIMSCenter,AdvancedMentalHealth Solutions.https://aims.uw.edu/collaborative-care.AccessedMarch11,2016. 4 Kessler,R.C.,etal.(2005).Lifetimeprevalenceandage-of-onsetdistributionsofDSM-IVdisordersintheNational ComorbiditySurveyReplication.ArchivesofGeneralPsychiatry,62,593-603.Formajordepressionalone,the chanceofhavingthediagnosisatsomepointinone’slifeisoneinsix. 5 Kessler,RC,Merikangas,R.&Wang,P.(April2008).ThePrevalenceandCorrelatesofWorkplaceDepressionin theNationalComorbiditySurveyReplication.JournalofOccupationalandEnvironmentalMedicine,50(4):381– 390. Increasing the Cost-Effectiveness of Depression Treatment with Collaborative Care – 03/2016 2 outofbalanceindepression.”6Recentstudieshaveshownthatthesamebiologicaland chemicalfactorsthattriggerdepressioncanalsoinfluenceheartdisease. Theimpactofanemployee’sdepressionextendsbeyondtheindividualtoaffectfamily,friends, coworkers,andeventually,thebottomline.Anindividualwithdepressionmaybewithdrawn andirritable,causingrelationshipswithfamilymembersandfriendstobecomestrained.Ifthe employeeisoneofthe15%ofindividualswithseveredepressionwhocommitssuicide,family members’riskforextremeguilt,depression,physicalhealthproblemsanddivorceare increased.Anemployeewithdepressionmayfrequentlycallinsick,missdeadlines,andappear unabletoconcentrate,frustratingco-workersandsupervisorswhoresentpickinguptheslack. Belowareexamplesofwhatdepressionanditseffectscanlooklikeintheworkplace: • Billhasbeenworkingontheassemblylineatamanufacturingplantsincehewas23 yearsold.Aftertwentyyearsonthejob,hewasthinkingabouttakinganearly retirementdealsohecouldtravel.Suddenly,withoutwarning,Billhadaheartattack. Recoverywashard,makingBillfeelweakandvulnerable.Hehadlessandless motivationtoexercise,followhisdiet,orkeeptrackofallhisdoctor’sappointmentsand medications.WheneverBillwouldthinkaboutgoingbacktowork,hisheartwouldrace. Convincedhewashavinganotherheartattack,Billendedupintheemergencyroom overandoveragain. • Sierraisa34-year-oldwomanwhoworkedherwayupfromasecretarialpositionto becomeanExecutiveVicePresidentatatelecommunicationscompany.Sheisaborn leaderandherdepartmentranunderbudgetforthefirstsixmonthsshewasincharge. However,duringherrisetothetop,herhusbandbecameincreasinglydepressed.He drankheavily,talkedaboutnothavinganythingtolivefor,andrefusedtogethelp. Sierraworriedabouthimconstantly,especiallywhenhewashomealonewiththekids. Sierrahadtroublesleepingatnightandcouldn’tconcentrateatwork.Shewasirritable, causingpreviouslyloyalstafftolookforotherjobs.Attheendoftheyear,Sierranoticed a$1,000,000errorinherannualbudget,forwhichshewouldlikelyloseherjob. • Sagebecamepregnantaftertwoyearsoftrying.Hercoworkerscelebratedwithherat herbabyshower,extractingpromisesfromherforlotsofbabypictureswhenshe returnedtowork.Ashorttimelater,Sagegavebirthtoahealthybabygirl.Forthefirst sixweeksafterthebirthofherdaughter,Sagewasinheaven.Shewastired,buthappy. Aroundweekseven,Sagestartedtofeelstrange.Shefelt“nothing”whenshelookedat herdaughteranddidn’twanttopickherupwhenshecried.Shewashavingintrusive thoughtsthatmadeherworryshewouldhurtherdaughter.Shefeltlikeshewasgoing crazy.SageandherhusbandfoughtallthetimebecauseSagewasunresponsivetoher daughter’sneed.Shewastooashamedtotellanyoneatworkwhatwashappening.So shebecameincreasinglyisolated,frequentlycallinginsicktowork. 6 WhatisDepression?NationalInstitutesofHealth.AccessedOctober27,2015.Retrievedfrom http://www.nimh.nih.gov/health/publications/depression/index.shtml. Increasing the Cost-Effectiveness of Depression Treatment with Collaborative Care – 03/2016 3 • At38,PhilipBurguiereswastheyoungestCEOevertorunaFortune500company.But hefeltempty.Hestartedtothinkthattheworldwouldbeabetterplacewithouthim. Fearfulofthestigmaassociatedwithdepression,heprovidedhisBoardofDirectors withadoctor’sletterindicatinghehadbrainchemistryproblemsthatrequiredasixmonthleaveofabsence.Thecompany’sstockfelltenpercentfollowingthe announcementofhisdeparturefor“healthreasons.” UntreatedDepressionIncreasesanEmployers’Costs MedicalOutcomesandCosts:Untreateddepressioncanincreasethechancesthatsomeonewill experienceamedicalcondition.Inaddition,individualswithdepressionandamedical conditionexperiencegreaterdistress,increasedfunctionalimpairment,andarelessableto followmedicalregimens.Asaresult,depressioncanincreasemedicalcostsandnegatively affecttreatmentoutcomes.Forexample: • Menandwomendiagnosedwithclinicaldepressionaremorethantwiceaslikelyto developcoronaryarterydiseaseorsufferaheartattack.7Inaddition,thosewhohave experiencedaheartattackarethreetimesaslikelytohaveacardiac-relateddeathif theyalsohaveaco-occurringdepressivedisorder.8,9 • Depressionoccursin10to27%ofstrokesurvivors,andthosewithco-occurring depressionwillhavea50%higherriskofmortality10inthenext29years.11 7 AmericanPsychologicalAssociation(n.d.).Mind/BodyHealth:HeartDisease.RetrievedNovember11,2015,from http://www.apa.org/helpcenter/heart-disease.aspx. 8 Sherrer,J.F.,Garfield,L.D.,Chrisciel,T.,etal.(2011).Increasedriskofmyocardialinfarctionindepressedpatients withtype2diabetes.DiabetesCare,34(8):1729-34. 9 Majordepressionanddepressivesymptomsarepositivelycorrelatedwithcardiacproblems,moregenerally,and increasingseverityofdepressionisassociatedwithearliermanifestationandgreaterseverityofcardiacevents. Afteramyocardialinfarctionevent(heartattack),individualswithdepressionhavetwicetheriskofanother cardiaceventwithintwoyearsofthefirstevent.Thisassociationcanbeexplainedbothbiologicallyand behaviorally.Individualswithdepressionhavemorebiomarkersthatarecorrelatedwithheartproblems. AccordingtoascienceadvisorygroupsponsoredbytheAmericanHeartAssociation,theseincludereducedheart ratevariability,evidenceofhypothalamic-pituitary-adrenaldysfunction,plasmaplateletproblems,impaired vascularfunction,andavarietyofothercirculatorysystemproblems.Behaviorallinksbetweendepressionand heartdiseaseincludedietandexercise,tobaccouse,stress,isolation,andmedicationadherence.Seeamore detaileddescriptionofthesefindingsin:Lichtman,J.H.,etal.(2008).Depressionandcoronaryheartdisease: Recommendationsforscreening,referral,andtreatment:AscienceadvisoryfromtheAmericanHeartAssociation preventioncommitteeofthecounciloncardiovascularnursing,councilonclinicalcardiology,councilon epidemiologyandprevention,andinterdisciplinarycouncilonqualityofcareandoutcomesresearch:Endorsedby theAmericanPsychiatricAssociation.Circulation,118(17),1768-1775. 10 Healthcarecostsinthelastyearoflifearemuchgreaterthaninotheryearsofaperson’slife.Seeforexample, Tanuseputro,P.,Wodchis,W.P.,Fowler,R.,etal.(2015).Thehealthcarecostofdying:Apopulation-based retrospectivecohortstudyofthelastyearoflifeinOntario,Canada.PLoSOne,10(3):e0121759. doi:10.1371/journal.pone.0121759. 11 MentalHealthAmerica.(n.d.).Co-OccurringDisordersandDepression.RetrievedNovember23,2015,from http://www.mentalhealthamerica.net/conditions/co-occurring-disorders-and-depression. Increasing the Cost-Effectiveness of Depression Treatment with Collaborative Care – 03/2016 4 Depressionoccursin25%ofpeoplewithdiabetes.12Patientswithsymptomsof depressionarelesslikelytoadheretodietaryrestrictionsormedicalregimens,and morelikelytousetheemergencyroomorinpatientsettings.13 • Depressionoccursin13to42%ofpatientswithrheumatoidarthritisandisassociated withworsehealthoutcomes,includinganincreasedriskofmortality.14 • Depressionincancerpatientsisoftenattributedtochemotherapysideeffects,whenin actualitydepressionismorelikelytocontributetoweightloss,fatigueanddepressed mood.Studiesalsoshowthatdepressioniscorrelatedwithhighermortalityratesin cancerpatients.15 • Nearlyone-thirdofpatientswithmajordepressivedisorderalsoabusealcoholor drugs.16Individualswhoabusealcoholordrugshaveincreasedmedicalcostsanduse expensiveformsofacutecaremoreoften.17 BusinessCost.Besidesincreasinghealthcareexpenses,researchshowsthatuntreated depressionisasignificantcontributortoworkplacedisabilitycosts,reducedworkperformance andpresenteeism,absenteeism,safetyissues,employeeturnoverandlegalcosts.Forexample: • While17to20%ofallworkersexperiencesshort-termdisabilityoverayear’stime, workerswithdepressionhavemorethandoublethatrate(upto48%)inanygiven12monthperiod.18 • Depressionwasnegativelycorrelatedwithoverallworkperformanceandproductivity, proficiencyincompletingjobtasks,andvoluntarilytakingonleadershiprolestohelp one’scoworkersorthecompanyinspecificways.19 • 12 Williams,M.M.,Clouse,R.E.,&Lustman,P.(2006).Treatingdepressiontopreventdiabetesandits complications:Understandingdepressionasamedicalriskfactor.ClinicalDiabetes,24(2),79-86. 13 Ciechanowski,P.S.,Katon,W.J.,&Russo,J.E.(2000).Impactofdepressivesymptomsonadherence,function, andcosts.JAMAInternalMedicine,160(21).Retrievedfrom http://archinte.jamanetwork.com/article.aspx?articleid=485556 14 Margaretten,M.,Julian,L.,Katz,P.,&Yelin,E.(2011).Depressioninpatientswithrheumatoidarthritis: Description,causes,andmechanisms.InternationalJournalofClinicalRheumatology,6(6),617-623. 15 Pinquart,M.&Duberstein,P.R.(2010).Depressionandcancermortality:Ameta-analysis.Psychological Medicine,40(11). 16 MentalHealthAmerica.(n.d.).Co-OccurringDisordersandDepression.RetrievedNovember23,2015,from http://www.mentalhealthamerica.net/conditions/co-occurring-disorders-and-depression. 17 RobinE.Clark,R.E.,O’Connell,E.,&Samnaliev,M.(March2010).SubstanceAbuseandHealthcareCosts KnowledgeAsset.SubstanceAbusePolicyResearchProgram.Retrievedfrom http://saprp.org/knowledgeassets/knowledge_detail.cfm?KAID=21. 18 Goldberg,R.J.,&Steury,S.(2001).Depressionintheworkplace:Costsandbarrierstotreatment.Psychiatric Services,52(12),1639-1643.Seealso:DepressionCenter,UniversityofMichiganHealthCenter.(n.d.).Depression andLostProductivity.RetrievedNovember23,2015,fromhttp://www.depressioncenter.org/work/informationfor-employers/lost-productivity/. 19 Ford,M.T.,Cerasoli,C.P.,Higgins,J.A.,&Decesare,A.L.(2011).Relationshipsbetweenpsychological,physical, andbehavioralhealthandworkperformance:Areviewandmeta-analysis.Work&Stress,25(3),185-204. Increasing the Cost-Effectiveness of Depression Treatment with Collaborative Care – 03/2016 5 • • • • • Inathree-monthperiod,individualswithdepressionmissedanaverageof4.8workdays andhad11.5daysofreducedproductivity.20 Whencomparedtohealthyemployeesoremployeeswithrheumatoidarthritis, employeeswithdepressionhadmoreabsenteeismandturnover.21 Dependingonthenatureandseverityofthedepression,aswellasthelevelofsupport intheworkplaceforrecoveryfromdepression,jobturnoverratesrangedfrom25to 50%amongworkersexperiencingdepression.Thecosttotheemployer(inrecruitment, trainingandotherorganizationalefforts)wasestimatedtobethree-quarterstooneand-a-halftimestheemployee’sannualsalary.22 Employeeswithdepressionaremoreaccident-pronebecauseofdepression's interferencewithconcentrationandfocus.23 Therehasbeena56%riseindepression-basedworkplacediscriminationclaimsfiled withtheEqualEmploymentOpportunityCommission(EEOC)between2003and2013.24 EffectiveDepressionTreatmentYieldsanAttractiveReturnonInvestment ImprovedMedicalOutcomesandReducedMedicalCosts.Studiesshowthateffective depressiontreatmentcanimprovemedicaloutcomesandreducemedicalcosts.Forexample: • Patientswhoreceivedearlyantidepressanttreatmentafterexperiencinganischemic strokehadsignificantlylowermortalityratescomparedtothosewhodidnotreceive antidepressanttreatment.25 • HemoglobinA1clevelsinpeoplewithdiabeteswereloweredwhenco-occurring depressionwastreated.26 • Antidepressanttreatmentofpatientswithasthmaresultedinareducedneedfor corticosteroids.27 • Simplepsychosocialinterventionsdeliveredbyspeciallytrainedhealthworkersreduced therateofpostpartumdepressioninwomen.28Totalcostsover12monthsforat-risk 20 Valenstein,M.,Vijan,S.,Zeber,J.E.,Boehm,K.,&Buttar.(2001).A.Thecost-utilityofscreeningfordepressionin primarycare.AnnalsofInternalMedicine,134,345-360. 21 Lerner,D.,Adler,A.,Chang,etal.(2004).Unemployment,jobretention,andproductivitylossamongemployees withdepression.PsychiatricServices,55(12),1371-1378. 22 Cocker,F.,Nicholson,J.M.,Graves,N.etal.(2014,September).Depressioninworkingadults:Comparingthe costsandhealthoutcomesofworkingwhenill.PLoSONE,9(9):e105430.Doi:10,137/journal.phone0105430. 23 Jacob,I.(2006,October).Depression’simpactonsafety.OccupationalHealthandSafety. 24 Dunning,M.(2014,December).Depressionintheworkplaceremainsproblematic,costsemployersbillions. BusinessInsurance.http://www.businessinsurance.com/article/20141207/NEWS03/312079961. 25 Mortesnsen,J.K.,Johnsen,S.P.,Larsson,H.&Andersen,G.(2015).Earlyantidepressanttreatmentandall-cause 30-daymortalityinpatientswithischemicstroke.CerebrovascularDiseases,40(1-2). 26 Penclofer,S.,etal.(2014,March).Stateofthescience:DepressionandType2Diabetes.WesternJournalof NursingResearch,1-25. 27 VanLieshout,R.J.,&MacQueen,G.M.(2012).Relationsbetweenasthmaandpsychologicaldistress:Anoldidea revisited.ChemImmunolAllergy,98,1-13. Increasing the Cost-Effectiveness of Depression Treatment with Collaborative Care – 03/2016 6 womenreceivingtheinterventionwere10%lowerforthedepressioninterventionthan withroutinecare,eventhoughthedepressioninterventionaddedtasksforhealth workers. ReducedBusinessCosts.Studiesalsoshowthatwhenpeoplewithdepressionreceiveeffective treatment,theyhaveanaverageof17fewerannualdisabilityleavedayscomparedtothose withdepressionwhodonotreceivetreatment.29Onestudyfrom2007showedthatindividuals whoreceivedtreatmentfordepressionhad23%lessabsenteeismandonlyonethirdasmany misseddaysofwork.30Thisstudywentontoreportthateffectivedepressiontreatmentledto aneconomicbenefitof$1,982associatedwithimprovedproductivityatworkand$619per personduetoreducedabsenteeism,31amountsthatarehigherintoday’sdollars. BarrierstoEmployeeUseofBenefitstoObtainTreatmentforDepression Althoughmorethan80%ofpeoplewithdepressioncanbetreatedsuccessfullywith medication,psychotherapy,oracombinationofboth,lessthan22%receiveadequatecare.32 Nearly74%ofAmericanswhoseekhelpforsymptomsofdepressiongotoaprimarycare physician(PCP)ratherthanamentalhealthprofessional.Unfortunately,adiagnosisof depressionismissed50%ofthetimeinaprimarycaresetting.Evenwhendepressionis diagnosedandaddressedbyaPCP,halfofpatientsprematurelystoptakingprescribed medicationsandmanydonotfollowthroughwithaspecialtyreferral. Forpatientswhoacceptamentalhealthorsubstanceusedisorder(MH/SUD)treatment referral,nearlyhalfofthemdropoutoftreatmentagainsttheirtherapist’sadvice.33Lackof awarenessofdepressivesymptoms,personalembarrassment,concernsaboutjobimpact, stigma,medicationsideeffects,psychiatristshortages,unrealisticexpectationsabouthowfast symptomswillgoaway,andtheburdenofweeklyclinicvisitspreventmanyindividualsfrom gettingthetreatmenttheyneedfordepression. 28 Morrell,C.J.,Warner,R.,Slade,P.etal.(2009).Psychologicalinterventionsforpostnataldepression:Cluster randomizedtrialandeconomicimpactevaluation(ThePoNDERtrial).HealthTechnologyAssessment,13(30):1153. 29 Donohue,J.M.,&Pincus,H.A.(2007).Reducingthesocietalburdenofdepression:Areviewofeconomiccosts, qualityofcareandeffectsoftreatment.Pharmacoeconomics,25(1),7-24. 30 Ibid.(Seealso:Langlieb,A.M.,&Kahn,J.P.(2005).Howmuchdoesqualitymentalhealthcareprofit employers?JournalofOccupationalandEnvironmentalMedicine,47(11),1099-1109.) 31 Ibid. 32 Kessler,R.etal.(2003).Theepidemiologyofmajordepressivedisorder:ResultsfromtheNationalComorbidity StudyReplication(NCS-R).JournaloftheAmericanMedicalAssociation,289(23),3095-3105. 33 DroppingOutofPsychotherapy,HarvardHealthPublications,HarvardMedicalSchool,October1,2005. Increasing the Cost-Effectiveness of Depression Treatment with Collaborative Care – 03/2016 7 RemovingBarrierstoEffectiveDepressionTreatment:TheCollaborativeCareModel Researchshowsthatimplementingspecificinterventions(collectivelyreferredtoas “CollaborativeCare”)thatpromotethedetectionofdepression,“in-place”treatment(no referralneeded),andtreatmentadherencecansignificantlyimproveoutcomesbyincreasing thenumberofindividualswhoaccessandsuccessfullycompletetreatmentfordepression.34 CollaborativeCareinterventionsincludestandardizeddepressionscreeninginprimarycare, tailoredpatienteducation,caremanagement(e.g.,carecoordinationandtriage,telephonic follow-up),andtechnology-enabledtreatmentplanmonitoring.Similartodiseasemanagement programsfordiabetes,theseinterventionspromoteearlyidentificationofdepression,improve treatmentengagement,andreducetreatmentdrop-outrates.Inaddition,integrating psychiatricconsultationintomedicalsettings,withaccountabilityforoutcomesandcosts, improvesmentalhealthandmedicaltreatmentoutcomeswhileultimatelyreducingthecostof care.35Table1illustrateshowCollaborativeCareinterventionspromoteeffectivetreatmentfor depression. Table1 TraditionalDepressionTreatment CollaborativeCareIntervention 50%PCPdepressiondetection Automateddepressionscreeningincreases detection 50%treatmentdrop-outrate Proactivepatientmonitoring,prioritizationof care,andfollow-upbycaremanagers 50%medicationadherence Sideeffecteducationandmonitoring, tailoreddosageadjustments,progress measurementandfollow-up Mentalhealthandmedicaltreatmentsilos thatmayresultincontra-indicated medicationinteractions,pooradherenceto treatmentregimensandredundanthealth carecosts Professionalcollaboration,consultationand treatmentplancoordination; implementationofadherencestrategiesfor medicalcare;identificationandtreatmentof co-occurringMH/SUDconditions; informationsharingviaelectronicrecords ButCollaborativeCareinterventionsdonotfitneatlywithinthebenefitdesignscommonly offeredbyemployers,andfewinsuranceplansreimburseforthesetypesofinterventions. 34 TheCollaborativeCareModelhasbeendescribedbytheAIMSCenterattheUniversityofWashington: http://uwaims.org 35 SeetheWashingtonStateInstituteforPublicPolicyathttp://www.wsipp.wa.gov/BenefitCostforarecentreview ofstudiesthatconcludedintegratedmentalhealth/physicalhealthcareinprimarycaresettingsiscost-effective. Increasing the Cost-Effectiveness of Depression Treatment with Collaborative Care – 03/2016 8 Employersandinsurersmustcollaborateandnegotiatetodevelopemployeebenefitplansthat supportCollaborativeCare. EmployerBenefitsandInsuranceCoverage Fee-for-serviceinsurancereimbursementforoutpatientmentalhealthandsubstanceuse disordertreatmentistypicallylimitedtoin-personvisitswithprofessionalsforpsychotherapy, medication,ordeliveryofaspecifictreatment(e.g.,electroconvulsivetherapy[ECT]). Administrationofdepressionscreeninginstruments,healthandbehaviorconsultsinthe medicalsetting,telephonicinterventionwiththepatient,casemanagement,treatment planning,psychologicalconsultswithoutthepatientpresent,progressmonitoring,andpatient educationarerarelyreimbursed.Employerswhowanttomoreeffectivelyaddressdepression mustpayprovidersorinsurerstodeliverCollaborativeCareinterventionstoreapmoreofthe benefitsofeffectivetreatmentfordepression. ExamplesofhowemployerscaninvestinCollaborativeCarefollow: 1. PayingforCollaborativeCareinterventionsthroughaninsureronacapitatedbasis(i.e.,a peremployeepermonthfeetoprovideallorsomeoftheelementsofcollaborativecare). Inthisapproach,theinsurerimplementsa“depressiondiseasemanagement(DDM)”or “caremanagement(CM)”programinwhichcaremanagershiredbytheinsurerprovide telephoniccasemanagementservices(e.g.,follow-upcalls,medicationchecks,care coordination,patienteducation,triage),arrangeforpsychologicalconsults,andmake recommendationsfortreatmentplanmodifications.Providerreimbursementfor administrationofdepressionscreeningtoolsandprogressmonitoringinstruments,health andbehaviorconsults,andmorethanoneprocedureinadayshouldalsobeincluded.This approachisbestsuitedforinsuredpopulationswithaccesstoalarge-scaleprovider network.DisadvantagesincludepatientrefusalstoparticipateintheDDMprogram,distrust ofmanagedcare,andcomplicationsassociatedwithproviders’inabilitytoidentify individualswhoseinsurancecoveragemakesthemeligiblefortheDDMprogram. 2. PayingforCollaborativeCareinterventionsonafee-for-servicebasisfornetworkproviders approvedtoimplementthem.Thisapproachalsoworksforlarge-scaleprovidernetworks andavoidstheproblemsassociatedwithmanagedcare.However,itrequiresprovider selectioncriteriaandCollaborativeCaretrainingresources,withincentivesthatencourage individualswithdepressiontoutilizequalifiedproviders.ThetypesofCollaborativeCare interventionsimplementedinthisapproachwilldependontheproviderdeliverysystem. (SeeDeliverySystemStructurebelow). 3. Payingacontainedhealthcaresystem,suchasanHMO,ormultispecialtyprovidergroup onacapitated,caserate(i.e.,payingafeetocoverCollaborativeCareforeachparticipant) orfee-for-servicebasistodeliverCollaborativeCareinterventions.Inthisapproach,trained CollaborativeCareprofessionalsareintegratedintothedeliverysystem,opportunitiesfor collaborationandin-personinterventionareincreased,andefficiencyisincentivized.This Increasing the Cost-Effectiveness of Depression Treatment with Collaborative Care – 03/2016 9 approachmaybegeographicallylimitedtotheregioninwhichthesystemorgroupis located. DeliverySystemStructure Regardlessofthefundingmechanism,acontinuumofCollaborativeCareinterventionsmustbe madeavailablesuchthatservicescanbetailoredtotheneedsofthepatientandseamlessly providedwithinthedeliverysysteminwhichtreatmentissought.Forexample,telephonic psychiatricconsultationandcaremanagementmaybebestsuitedtosupportaPCPwho practicesinasmallgrouporruralsetting,whileanonsitebehavioralhealthprofessional availableforconsultationand“warmhandoffs”fromPCPs(introducingthepatientin-personto amentalhealthprovider)mayprovideoptimalassistancetoamultispecialtymedicalclinic.For individualswithseveresymptomsofdepression,moreintensive,specializedtreatmentat centersofexcellencethatimplementCollaborativeCareinterventionsshouldbeavailableand accessible. Additionally,providersdeliveringCollaborativeCareinterventionsmustbequalifiedand adequatelytrained.Treatmentprofessionalsmustlikelyaddnewskillstotheirrepertoire, includingtheabilitytoregularlytrackandreviewelectronicpatientdata,engagewithpatients betweensessions,triageandprioritizecare,delivershort-terminterventionsasneeded,and providespecificandconciseconsultationwhileparticipatingasamemberofafast-paced medicalteam. Tofullytransformabehavioralhealthpracticeand/ortrainclinicianstoprovidethefullrangeof CollaborativeCareinterventions,start-upfundingmayberequired.Investmentsinscreening andoutcomemeasurementtools,trackingsystems,electronicmedicalrecords,communication systems,changestobillingsystems,transportationexpenses,andongoingprovidertrainingand supervisionwillbeanimportantcomponentofthesuccessofanydeliverysystemthatincludes CollaborativeCareinterventions. CollaborativeCareisCost-Effective CollaborativeCareinterventionsmakedepressiontreatmentmoreeffectivebecausethey addresshealthcaresystemflawsthatpreventoptimaldeliveryofevidence-basedservices.And, whileintheshort-runimplementingCollaborativeCareinterventionsaddstothecostof depressiontreatment,theoveralleffectistolowercosts. Researchonthecost-effectivenessofCollaborativeCareinterventionscomparedtothatof treatmentfordepressiononitsownisrelativelynew,buttheresultsarepositive.The WashingtonStateInstituteforPublicPolicy(WSIPP)foundthatCollaborativeCareinterventions hadastatisticallysignificantimpactondepressionoutcomes,astatisticallyinsignificant Increasing the Cost-Effectiveness of Depression Treatment with Collaborative Care – 03/2016 10 increaseincostofcare,reducedlifetimehealthcareexpenses,andbetterlabormarket outcomes(e.g.,turnover,unemployment),withnocombinationofassumptionsresultingin CollaborativeCarefailingabenefitcosttest.36Severalstudiesevaluatingthecost-effectiveness ofCollaborativeCareinterventionsrelativetoroutinecareinprimarycaresettings demonstratedhealthcaresavingsovertime.37Agoodestimateoftheinvestmentinenhanced treatmentis$1,000overtwoyearsperpersontreatedfordepression.38However,healthcare savingsoverfouryearshavebeenestimatedtobeapproximately$3,300perperson; productivityandabsenteeismsavingsinthefirsttwoyearshavebeenestimatedtobe approximatelyanother$2,500perpersontreated.39 Inconclusion,thereturnoninvestmentinCollaborativeCarestrategiesisreducedhealthcare costsovertime,improvedhealthcareoutcomes(forbothmentalhealthandphysicalhealth), decreasedbusinesscostsrelatedtodisability,productivity,absenteeismandturnover,and improvedqualityoflifeforemployeesandtheirfamilies. HowtheMeadowsMentalHealthPolicyInstituteCanIncreasetheCost-Effectiveness ofDepressionTreatmentthroughCollaborativeCare TheMeadowsMentalHealthPolicyInstitute’s(MMHPI)roleinpromotingCollaborativeCareto enhanceaccesstoeffectivetreatmentfordepressionincludesthefollowingthreecomponents: 1. WorkingwithEmployers:MMHPIwillidentifyandworkwithemployerswhoare interestedinimplementingCollaborativeCare.MMHPIcanconsultwiththese employersregardingbenefitdesign,assistwithrequestsforproposals(RFPs)for insurersand/ormultispecialtyprovidergroups,anddesignpilotsorstudiestomeasure cost-effectivenessoftheseprojectsfromtheemployer’sperspective,includingfactors suchastotalhealthinsurancepremiums,laborproductivity,andlaborturnover. 36 WashingtonStateInstituteforPublicPolicy(December2015).Benefit-costresults:CollaborativePrimaryCare forDepressionwithComorbidMedicalConditions.Olympia,WA:Author. 37 Grochtdrels,T.,Brettschneider,C.,Weggener,A.etal.(2015).Cost-effectivenessofcollaborativecareforthe treatmentofdepressivedisordersinprimarycare:Asystematicreview.PLoSONE10(5):e0123078. doi:10.1371/journal.pone.0123078. 38 InstituteforClinicalSystemsImprovement.(n.d.).TheValueofProvidingCollaborativeCareModelsforTreating EmployeeswithDepression.Seealso“AnewdirectionindepressiontreatmentinMinnesota:DIAMONDprogram, InstituteforClinicalSystemsImprovement,Bloomington,Minnesota,”APAAchievementAward(2010).Psychiatric Services,61(10),1042-1044. TheDIAMOND(DepressionImprovementAcrossMinnesota,OfferingaNewDirection)Projectchangeshowcare forthepatientwithdepressionisdeliveredandpaidforinprimarycare.Itsscopeis“toassistprimarycarein developingsystemsthatsupporteffectiveassessment,diagnosisandongoingmanagementofneworexisting diagnosisofmajordepressioninadultsage18andover,andtoassistindividualstoachieveremissionof symptoms,reducerelapseandreturntopreviousleveloffunctioning.” 39 Ibid. Increasing the Cost-Effectiveness of Depression Treatment with Collaborative Care – 03/2016 11 2. HelpProvidersImplementCollaborativeCare:MMHPIwillcollaborativelyworktosecure fundingforprovidergroupsornetworksinterestedindevelopingtheinfrastructureand expertisenecessarytoprovidethefullcontinuumofCollaborativeCareinterventions. MMHPIcanassistthesegroupswithtailoringtheirservicestotargetedmedicaldelivery systemsbyfillingresourcegapswithintheservicearea,facilitatingintegrationwiththe existingmedicalsystem(s),andbrokeringtraininginCollaborativeCarestrategies. 3. EvaluateandSupportCollaborativeCareSystemsOnceOperational:MMHPIcould conductreadinessreviewsofhealthcaredeliverysystems,and/orauditsofCollaborative Caredeliverysystemsorstrategiesaftertheyareoperational,toidentifytraining opportunities,providecoachingincost-effectiveCollaborativeCareinterventions,and secureevidenceofimprovedtreatmentofdepression,comorbidhealthoutcomes,and reducedcosts.Datafromthesereviewscanpersuadeotheremployersaboutthe importanceofofferingcoverageforCollaborativeCarestrategies.