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How Often Does my Blood Type Occur? Section ___ Name _________________ Introduction: There are four blood types: A, B, AB, O. Here are the percentages of the types in the US population. Type O = 44% Type A = 37% Type B = 13% Type AB = 6% We know how to find out what type of blood each person has and we think that the different blood types are related to germs. When you get germs or bacteria in your body, your body starts fighting them. Some of your white blood cells act like amoebas and eat and digest the bacteria. Other cells produce chemicals called ANTIBODIES, which help destroy the bacteria. The bacteria have certain chemicals on the cells, called ANTIGENS. These antigens cause your body to make antibodies. Each antigen has a matched antibody. It is the same way with blood. For each blood antigen, A and B, there is a special antibody: antibody A and antibody B. Type a has antigen A, Type B has antigen B. If you have Type AB blood, you have antigen A and antigen B on your red blood cells. The antibodies cause the cells to “clump” together. This “clumping” is called agglutination. Knowing about the different blood types has improved blood transfusion as well as allowing better matches with transplanted organs and tissues which require even more detailed research. Fill in the antibodies in the chart below: BLOOD TYPE ANTIGENS Type A A Type B B Type AB AB Type O None ANTIBODIES Explain why someone with Type A blood cannot be given Type B or type AB blood: ________________________________________________________________ ________________________________________________________________ Explain why someone with Type O blood is thought to be a universal donor: ________________________________________________________________ ________________________________________________________________ How_Often_Does_my_Blood_Type_Occur_2006 1 The chart is based on the hypothesis that there are 3 genes for blood type rather than the usual 2. It is possible for any person to have 2 of the possible 3 genes. There is a gene for Type A blood, a gene for Type B blood, and a gene for Type O blood. The O gene is recessive to the other 2 genes (A and B). A person with both an A gene and a B gene will have Type AB blood. Complete the chart by circling who the other parent can be, and cannot be. Draw Punnet squares if you need help figuring out possible parentage. Possible Blood Type of a Baby and His Parents If the baby is blood type… And one parent is… O Then the other parent can be but cannot be O A, B, AB, O A, B, AB, O O A A, B, AB, O A, B, AB, O O B A, B, AB, O A, B, AB, O O AB A, B, AB, O A, B, AB, O A O A, B, AB, O A, B, AB, O A A A, B, AB, O A, B, AB, O A B A, B, AB, O A, B, AB, O A AB A, B, AB, O A, B, AB, O B O A, B, AB, O A, B, AB, O B A A, B, AB, O A, B, AB, O B B A, B, AB, O A, B, AB, O B AB A, B, AB, O A, B, AB, O AB O A, B, AB, O A, B, AB, O AB A A, B, AB, O A, B, AB, O AB B A, B, AB, O A, B, AB, O AB AB A, B, AB, O A, B, AB, O How_Often_Does_my_Blood_Type_Occur_2006 2 How do genes control the Rh factor? Although several genes are involved in controlling Rh, we will simplify the matter by representing it as Rh+ as dominant and Rh- as recessive. Therefore, Someone: Someone: Someone: Rh+ Rh+ is Rh positive (+) Rh+ Rh- is Rh positive (+) Rh- Rh- is Rh negative (-) The chart below shows pairs of Rh genes that parents could have. For each combination of parent genes, some pairs of offspring genes are possible. Other pairs of offspring genes are impossible. Look at the first line. It shoes that ++ is the only pair of gene a child of these parents could have. Now, you complete the rest of the chart. Write in the space provided, the pairs of genes that the children of each set of parent could have. Notice that in some cases more than one pair of genes is possible. Gene Pair of First Parent Gene Pair of Second Parent Possible Gene Pairs of Children + + + + + + + + + - + + - + - + - + - - - - - - - - How_Often_Does_my_Blood_Type_Occur_2006 3 How_Often_Does_my_Blood_Type_Occur_2006 4