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8/22/2016 Life: Chemical, Cellular, and Evolutionary Foundations Chapter 1 Core Concepts 1.The scientific method is a deliberate way of asking and answering questions about the natural world. 2.Life works according to fundamental principles of chemistry and physics. 3.The fundamental unit of life is the cell. 4.Evolution explains the features that organisms share and those that set them apart. 5.Organisms interact with one another and with their physical environment, shaping ecological systems that sustain life. 6.In the 21st century, humans have become major agents in ecology and evolution. Observe this image Biology: The Science of How Life Works • Molecular mechanisms of cells • Integrated actions of many cells within an organ or body • Interaction among different organisms in nature Concept 1.1: Scientific Method • Observation allows us to draw tentative explanations called hypothesis. • Hypothesis makes predictions that can be tested by experiments • A hypothesis supported by many experiments and observations can become a theory. How do scientist study Biology? • • • • • • Observation Asking questions Hypothesis Design an experiment Collect data Conclusion 1 8/22/2016 Concept 1.2 Life works according to fundamental principles of chemistry and physics What is common between living and COMPOSITION OF EARTH AND HUMAN BODY nonliving things? • What’s the difference between the living and nonliving environment? • Earth’s crust: - Mainly Oxygen and Silicon • Living organisms: - Oxygen, Carbon, Hydrogen and nitrogen. What are the characteristics of life? 1. Complex 2. Able to change in response to environment 3. Able to reproduce 4. Have the capacity to evolve 5. Process energy ODYNAMICS How do organisms obtain energy? • From sunlight or food. • First Law of thermodynamics states that energy can neither be created nor destroyed Organisms come from other living organisms. Life does not spontaneously arise from nonliving matter FRANCESCO REDI EXPERIMENTATION Science as a Process Louis Pasteur Experimentation Broth remains clear and sterile—no microbes appear. Straight‐ neck flask Broth Swan‐ neck flask Boiling kills all the microbes, thereby sterilizing the broth. Dust particles carrying microbes enter the straight‐neck flask, but not the swan‐neck flask. Broth becomes cloudy because of growth of microbes. Figure 1.9 Can microscopic life arise from nonliving matter? 2 8/22/2016 Concept 1.3: Cells Cell: the simplest self-replicating entity that can exist as an independent unit of life ESSENTIAL FEATURES OF A CELL What is a Cell? Cell is a basic unit of life. It varies in shape and size • It can store and transmit information. • It has a plasma membrane. • It can harness energy from the environment. STORE AND TRANSMIT INFORMATION Nucleic Acids Store and Transmit Information • Information is stored in DNA. It’s a double helix with each strand made of four different molecules (A,C,G &T) • DNA has instructions to make proteins, the molecule that does the work of the cell. THE CENTRAL DOGMA Flow of Information in all Living Organisms • Central Dogma: DNA→RNA → Protein • Gene – a segment of DNA that has instructions to make a specific protein • Genes are made of DNA • Genes control protein production indirectly • DNA is transcribed into RNA then translated into a protein • Gene expression is the process of converting information from gene to cellular product (protein) 3 8/22/2016 PLASMA MEMBRANE Plasma membrane Two Main Forms of Cells Outside of cell • Separates the cell from its environment • Controls exchange of material between cell and the environment Cytoplasm All cells • are all enclosed by a membrane • Use DNA as the genetic material • Two main forms of cells – Eukaryotic‐ nucleus & organelles present – Prokaryotic‐nucleus and organelles absent Transmission electron micrograph of a cell TREE OF LIFE: Three Domains of Life Most of life’s diversity, and so most of its deep evolutionary history, is microbial. ARCHAEA BACTERIA EUKARYOTES Plants Proposed position of root Time runs from the root to the branches. All land plants lie on this branch. Animals Animal diversity lies on this branch of the tree. Domain Eukarya • The domain Eukarya includes all eukaryotic organisms. • Eukarya includes three multicellular kingdoms – Plantae: Autotrophs – Fungi: heterotrophs, absorb nutrients – Animalia: heterotrophs, ingest nutrients • Other eukaryotic organisms were formerly grouped into the Protist kingdom (unicellular/multicellular, autotroph/heterotroph) though these are now often grouped into many separate kingdoms Domain Bacteria and Archaea • Domain Bacteria: Unicellular diverse prokaryotes • Domain Archaea: Prokaryotes that live in earth’s extreme environments such as salty lakes, boiling hot springs • Most prokaryotes are single‐celled and microscopic Aren’t viruses smaller than cells? What are Viruses? Shouldn’t they be considered the smallest living organisms? A. A virus can store and transmit information. B. A virus has a plasma membrane (protein coat). C. A virus can harness energy from the environment. D. They can reproduce on their own 4 8/22/2016 Aren’t viruses smaller than cells? What are Viruses? Shouldn’t they be considered the smallest living organisms? A. A virus can store and transmit information. B. A virus has a plasma membrane (protein coat). C. A virus can harness energy from the environment. D. They can reproduce on their own Concept 1.4: Evolution ‐ Change over time • Fossils and other evidence document the evolution of life on Earth over billions of years Variation Environmental Genetic PHYLOGENETIC TREE IN PRIMATES • Evolution explains patterns of unity and diversity in living organisms • Similar traits among organisms are explained by descent from common ancestors • Differences among organisms are explained by the accumulation of heritable changes • Charles Darwin published On the Origin of Species by Means of Natural Selection in 1859 • Darwin made two main points: – Species showed evidence of “descent with modification” from common ancestors – Natural selection is the mechanism behind “descent with modification” • Darwin’s theory explained the duality of unity and diversity • Darwin observed that: – Individuals in a population have traits that vary – Many of these traits are heritable (passed from parents to offspring) – More offspring are produced than survive – Competition is inevitable – Species generally suit their environment 5 8/22/2016 Concept 1.5: Ecology The study of how organisms interact with one another and with their environment Concept 1.6: Human Footprint What is our role in evolution? Some species have benefited Some species have not benefited from human activity 6