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PowerPoint Presentation to accompany Hole’s Human Anatomy and Physiology, 9/e by Shier, Butler, and Lewis Chapter 5 Tissues Tissues • Cells are organized into layers or groups called tissues. • There are four major tissue types found in the body: epithelial, connective, muscle, and nervous. • These tissues associate and interact to form organs and specialized functions. Epithelial Tissue • Epithelium functions in protection, secretion, absorption, and excretion. • It is composed of tightly packed cells anchored to a basement membrane. • Epithelium lacks blood vessels and rapidly divides. • Epithelial tissues are classified by cell shape and number of cell layers. Simple Squamous Epithelium • Simple squamous epithelium consists of a single layer of thin, flat cells that fit tightly. Figure 5.1 Simple Squamous Epithelium • It functions in filtration, diffusion, osmosis, and covers surfaces. • It is found in air sacs of the lung, walls of capillaries, lines blood vessels, and covers the membranes that line body cavities. Simple Cuboidal Epithelium • Simple cuboidal epithelium consists of a single layer of cubeshaped cells. Figure 5.2 Simple Cuboidal Epithelium • It functions in secretion and absorption. • It is found on the surface of the ovaries, linings of kidney tubules, linings of the ducts of certain glands. Simple Columnar Epithelium • Simple columnar epithelium is a single layer of elongated, columnshaped cells. Figure 5.3 Simple Columnar Epithelium • It functions in protection, secretion, and absorption. • It can be ciliated or nonciliated. Simple Columnar Epithelium • Specialized goblet cells secrete mucus. • It is found lining the uterus, stomach, and intestines. Pseudostratified Columnar Epithelium • Pseudostratified columnar epithelium is a single layer of elongated cells that appears to be more than one layer. Figure 5.5 Pseudostratified Columnar Epithelium • It is often ciliated and contains goblet cells. • It functions in protection, secretion, and movement of mucus and cells. • It is found lining the respiratory passages. Stratified Squamous Epithelium • Stratified squamous epithelium consists of many layers of cells with flat cells on the outer layers. Figure 5.6 Stratified Squamous Epithelium • It functions in protection. • It is found in the outer layer of the skin, linings of the oral cavity, throat, vagina, and anal cavity. Stratified Cuboidal Epithelium • Stratified cuboidal epithelium consists of two to three layers of cubedshaped cells. Figure 5.7 Stratified Cuboidal Epithelium • It functions in protection. • It is found in the linings of the mammary glands, sweat glands, salivary glands, and pancreas. Stratified Columnar Epithelium • Stratified columnar epithelium consists of a top layer of elongated cells, and lower layers of cubeshaped cells. Figure 5.8 Stratified Columnar Epithelium • It functions in protection and secretion. • It is found in the vas deferens, part of the male urethra, and parts of the pharynx. Transitional Epithelium • Transitional epithelium consists of many layers of cube-shaped and elongated cells. Figure 5.9a Transitional Epithelium • It functions in distensibility and protection. • It is found in the inner lining of the urinary bladder, ureters and part of the urethra. Figure 5.9b Glandular Epithelium • Glandular epithelium is composed of cells that produce and secrete substances. • Exocrine glands secrete products into ducts. • Endocrine glands secrete products into tissue fluid or blood. • A unicellular exocrine gland is the mucoussecreting goblet cell. Multicellular Glands • A simple gland communicates with the surface through one unbranched duct. Figure 5.10 Multicellular Glands • A compound gland communicates with the surface through a branched duct. • Tubular glands are epithelial-lined tubes. • Alveolar (acinar) glands have saclike endings. Glandular Secretion • Merocrine glands release fluid through exocytosis. Ex: salivary glands. Figure 5.11 Glandular Secretion • Apocrine glands release cellular product by pinching off the free end of the cell. Ex: mammary glands. Glandular Secretion • Holocrine glands secrete the entire cell full of the secretory product. Ex: sebaceous glands. Merocrine Secretion • Most exocrine glands are merocrine. • There are two types of merocrine cells, serous and mucous. • Serous fluid is watery with a high enzyme concentration. • Mucous cells secrete a mucus, a thick fluid rich in the glycoprotein, mucin. Connective Tissues • Connective tissue is the most abundant tissue in the body. • Extracellular material, matrix, makes up the bulk of the tissue. • Matrix is composed of fibers and ground substance. • Connective tissue cells usually can divide. Connective Tissue Cell Types • Fibroblasts secrete protein into the matrix. Figure 5.13 Connective Tissue Cell Types • Macrophages originate as white blood cells. They can move and phagocytize foreign particles. Figure 5.14 Connective Tissue Cell Types • Mast cells release heparin, which prevents blood clotting, and histamine, which aids in the inflammatory response. Figure 5.15 Connective Tissue Fibers • Collagenous fibers, white fibers, are made of thick threads of collagen. They are strong, flexible, and inelastic. Figure 5.16 Connective Tissue Fibers • Elastic fibers, yellow fibers, are made of bundles of elastin. • Reticular fibers are thin,collagenous fibers that form branched networks for support. Loose Connective Tissue • Loose connective tissue or areolar tissue binds organs together and holds tissue fluids. Figure 5.18 Loose Connective Tissue • It is cells (fibroblasts) in a fluid-gel matrix. • It forms thin membranes found beneath the skin, between muscles, and beneath epithelial tissue. Adipose Tissue • Adipose tissue protects, insulates, and stores fat in droplets inside the cells. Figure 5.19 Adipose Tissue • It consists of cells (adipocytes) in a fluid-gel matrix. • It is found beneath the skin, around the kidneys, behind the eyes, and on the heart. Reticular Connective Tissue • Reticular connective tissue supports organs. Figure 5.20 Reticular Connective Tissue • It is composed of thin, collagenous fibers and cells in a fluid-gel matrix. • It is found in the walls of the liver, spleen, and lymphatic organs. Dense Connective Tissue • Dense connective tissue binds organs together. Figure 5.21 Dense Connective Tissue • It is composed thick collagenous fibers, thin elastic fibers and fibroblasts in a fluid-gel matrix. • It is found in tendons, ligaments, and the dermis of the skin. Elastic Connective Tissue • Elastic connective tissue supports, protects, and provides a flexible framework. Figure 5.22 Elastic Connective Tissue • It consists of elastic fibers and fibroblasts in a solid-gel matrix. • It connects vertebrae and is found in the walls of arteries and airways. Cartilage • Cartilage is a rigid connective tissue. • The matrix consists of collagenous fibers in a gel-like ground substance. • Cartilage cells, chondrocytes, are found in small chambers, lacunae. • Cartilage is covered with a thin layer of connective tissue, the perichondrium. • Cartilage lacks blood vessels. Cartilage • Cartilage cells, chondrocytes, are found in small chambers, lacunae. • Cartilage is covered with a thin layer of connective tissue, the perichondrium. • Cartilage lacks blood vessels. Hyaline Cartilage • Hyaline cartilage supports, protects, and provides a framework. • It is the most common type of cartilage. Figure 5.23 Hyaline Cartilage • It is found in the ends of bones, nose, and rings in the respiratory passages. • Hyaline cartilage provides the embryonic model for the skeleton. Elastic Cartilage • Elastic cartilage supports, protects, and provides a flexible framework. Figure 5.24 Elastic Cartilage • Its matrix contains many elastic fibers. • It is found in the outer ear and part of the larynx. Fibrocartilage • Fibrocartilage supports, protects, and absorbs shock during body movement. Figure 5.25 Fibrocartilage • It is the toughest type of cartilage. • It is found between the vertebrae (intervertebral discs), in the knee and parts of the pelvic girdle. Bone • Bone supports, protects, provides a framework for muscle attachment. Figure 5.26 Bone • It is composed of cells (osteocytes) in a hard calcified matrix. The osteocytes are located in layers, lamellae, organized into osteons. Bone • It is found in the skeleton and middle ear. Blood • Blood transports gases, nutrients, and wastes, defends against disease, and acts in clotting. Figure 5.27 Blood • It is composed of cells and platelets in a fluid matrix, the blood plasma. • It is found within the blood vessels. Muscle Tissue • Muscle tissue is contractile. • Muscle fibers can shorten and thicken. • There are three types of muscle tissue: skeletal, smooth, and cardiac. Skeletal Muscle • Skeletal muscles attach to bones and are controlled by conscious effort. Figure 5.28 Skeletal Muscle • It is also called voluntary muscle. Skeletal Muscle • The muscle cells have many nuclei and exhibit light and dark banding patterns called striations. • Skeletal muscles contract in response to nerve signals. Smooth Muscle • Smooth muscle appears smooth because it lacks striations. • Smooth muscle action is not under conscious control and it is called involuntary. Figure 5.29 Smooth Muscle • The cells are spindle-shaped with a central nucleus. • Smooth muscle is found in the stomach, intestines, uterus, and blood vessels. Cardiac Muscle • Cardiac muscle tissue is found only in the heart. Figure 5.30 Cardiac Muscle • The striated cells are joined end to end with a specialized intercellular junction called an intercalated disk. • Cardiac muscle is under involuntary control. Figure 5.30 Nervous Tissues • Nervous tissues are found in the brain, spinal cord, and peripheral neurons. Figure 5.31 Nervous Tissues • Nerve cells or neurons sense changes and transmit signals. Nervous Tissues • Neuroglia are cells that support and bind nervous tissue. They supply nutrients, carry on phagocytosis, and play a role in cell to cell communication.