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Theory (10 questions) 1. A B C D E Displaying the distribution of a categorical variable Histogram Bar chart or pie chart scatterplot mean and standard deviation plot box diagram 2. What happens to the measures of the dispersion when adding the same number to each data value? Adding the same number to each data value in a variable does not change measures of dispersion Adding the same number to each data value in a variable shifts each measures of dispersion by the amount added Adding the same number to each data value in a variable shifts multiplies measures of dispersion by the amount added Adding the same number to each data value in a variable shifts each measures of dispersion by 2 units Adding the same number to each data value in a variable shifts each measures of dispersion by 2 units to the opposite direction A B C D E 3. A B C D E 4. A Definition of positive predictive value (PPV) A conditional probability: the probability of a negative test result once the person is healthy A conditional probability: the probability of a positive test result once the person has the disease A conditional probability: a probability that someone really does not have the disease once the test has given a negative result All of them A conditional probability: a probability that someone does have the disease once the test has given a positive result E The meaning of a confidence interval An interval which contains the probability of the (unknown) population parameter is the given value. An interval which contains the value of the (known) population parameter with unknown, but high probability. An interval which contains the value of the (unknown) population parameter with (given) high probability An interval which contains the value of the (known) population parameter with unknown probability An interval which contains the sample mean with unknown, but low probability 5. A B C D E What is (are) the assumption(s) of the two-sample t-test? Independent samples, normality and equality of variances. Dependent samples, normality and equality of variances. Independent samples, normality and equality of ranges. Dependent samples, normality and equality of medians. Independent samples, equality of medians and variances. B C D 6. A B C D E What is Type II Error? If a null hypothesis is incorrectly rejected when it is in fact true. If a null hypothesis is correctly rejected because it is true. When a null hypothesis is not rejected despite being false. When a null hypothesis is correctly not rejected because it is false. When the null- and the alternative hypothesis are also true. 7. A B C D E Which of the following is NOT true for the coefficient of correlation? If the regression line is decreasing, the coefficient of correlation is negative. Shows the value of the slope of the regression line Its value is between -1 and 1 . If its value is 1, there is a perfect linear relationship between the two variables If its value is -1, there is a perfect linear relationship between the two variables 8. A B C D E The aim of test of independence. The three variables are independent or not. The two variables are independent or not. Calculate the mean of population. Make the contingency table. Calculate the expected frequencies. 9. A D E Decision of nonparametric tests in case of small sample size (based on tables) The null hypothesis is accepted when the test statistic (sum of ranks) lies outside the interval given it table for the test The null hypothesis is accepted when the test statistic (sum of ranks) lies in the interval given it table for the test The null hypothesis is rejected when the test statistic (sum of ranks) lies in the interval given it table for the test The null hypothesis is rejected when 0 lies in the interval given it table for the test The null hypothesis is rejected when 0 lies outside the interval given it table for the test 10. A B C D E Which of following statistic we use to measure agreement? kappa alpha beta rho mu B C Correct answers: 1B, 2A, 3E, 4C, 5A, 6C, 7B, 8B, 9B, 10A Problems and calculations (10 questions) 11. A B C D E 12. A B C D E 13. A B C D E 14. A B C D E 15. A B C D E Given the following of the following small sample: X: 4 ; 1 ; 5 ; 4 ;1 , Calculate the mean and median Mean=3, median=4 Mean=3, median=5 Mean=5, median=5 Mean=5, median=4 Mean=3, median=3 In a study, a diagnostic test detected 270 true positive and 30 true negative samples of a total of 300 tests. What is the positive predictive value (PPV) of this test? PPV is 0.3 PPV is 0.9 PPV is 1 PPV is 1/9 PPV is 0.1 In a study, systolic blood pressure of 10 healthy women was measured. The mean was 119, the standard error 0.664. Calculate the 95% confidence interval for the population mean! (α=0.05, ttable=2.26). Interval is: (124.73, 125.27) Interval is: (120.89, 123.11) Interval is: (123.36, 124.64) Interval is: (117.5, 120.5) Interval is: (116.84, 121.16) Systolic blood pressure of 10 healthy women was measured. The sample mean=119, the standard error=0.664. Supposing that the sample was drawn from a normal distribution, check whether the population mean is 125! Find the null- and alternative hypotheses. H0: the population mean is=125, HA: the population mean is not 125 H0: the population mean is not 125, HA: the population mean is = 125 H0: the population mean is=119, HA: the population mean is not 119 H0: the population mean is=119, HA: the population mean is not 125 H0: the population mean is=119, HA: the population mean is 125 First-year medical students were asked about their age. The results: boys: n=78, mean=21.26, SD=2.98, girls: n=59, mean=19.9, SD=2.454. To test the null hypothesis (H0: the mean age of boys and girls is the same), what is the appropriate test? Chi-squared test to test whether the population means are equal. Independent samples t-test (two sample t-test) to test whether the population means are equal. One sample t-test to test whether the mean difference between paired observations is zero. Paired t-test to test whether the mean difference between paired observations is zero. Paired t-test to test whether the population means are equal. 16. A B C D E 17. A B C D E 18. A B C D E 19. A B C D E 20. A B C D E Medical students were asked about their age. Is there a significant difference in the mean age of boys and girls at 5% level, if the p-value is p=0.0051, the test statistic is t=2.841, the critical value in the t-table is t0.05,135=1.96? No, because p = 0.0051 < 0.05. Yes, because p = 0.0051 < 1.96. Yes, because p = 0.0051 < 0.05. No, because p = 0.0051 < 2.841. Yes, because p = 0.0051 < 0.95. The correlation coefficient of two variables based on a sample of 10 observations is 0.71. We want to know if there is a linear connection between the variables. What are the hypotheses of the test used to answer this question? H0: ρ = 0, HA: ρ ≠ 0 H0: ρ = 0.71, HA: ρ ≠ 0.71 H0: R = 0, HA: R ≠ 0 H0: ρ = 1, HA: ρ ≠ 1 H0: R = 0.71, HA: R ≠ 0.71 The correlation coefficient of two variables based on a sample of 32 observations is 0.28. We want to know if there is a linear connection between the variables (at an α level of 0.05). What is the value of the test statistic? 1.649 1.807 9.114 5.705 1.597 Control and patients with CHD illness were compared. Test the null hypothesis that the illness is independent of sex. The test statistic is 6.68 (α=0.05, χ2table=3.84). χ2> χ2table, so the difference is not significant at 5% level, illness is dependent on sex χ2> χ2table, so the difference is significant at 5% level, illness is independent of sex χ2< χ2table, so the difference is significant at 5% level, illness is independent of sex χ2> χ2table, so the difference is not significant at 5% level, illness is independent on sex χ2> χ2table, so the difference is significant at 5% level, illness is dependent on sex In a study 40 HPV positive tests of 50 abnormal cervical samples and 10 HPV positive tests of 60 normal cervical samples were detected. Calculate the odds ratio to estimate the risk ! 10 15 5 20 2 Correct answers: 11A, 12C, 13D, 14A, 15B, 16C, 17A, 18E, 19E, 20D