Download Figure 1: A pedigree chart (family tree) identifying blood genotypes

Figure 1: A pedigree chart (family tree) identifying blood genotypes.
Lynch syndrome cancer risk is inherited in an autosomal dominant pattern, which means one
inherited copy of the altered gene in each cell is sufficient to increase cancer risk. Sussanah has the
heterozygous genotype for Lynch syndrome. Her husband, Paul, has the homozygous genotype for the
normal condition (no Lynch syndrome).
Short Story 1: Lynch syndrome
Syndactyly, also known as mulefoot, in cattle is inherited as an autosomal recessive trait. A bull
named Edgar is suspected of carrying a recessive allele for syndactyly. A cow named Mary has
syndactyly; it is very difficult for her to walk, because the two toes on her feet are fused together. A cow
named Rhoda is a carrier for syndactyly. A cow named Phyllis does not have syndactyly and is not a
carrier for syndactyly.
Short Story 2: Syndactyly
Red Star chickens are gender linked for color. The females are red and the males are white. This
makes it especially easy to sort chicks when they hatch. People interested in raising chickens for eggs
should select red chicks. People interested in raising chickens for meat should select white chicks.
Short Story 3: Red Star chickens
Hemophilia is a bleeding disorder that slows the blood clotting process. People with this
condition experience prolonged bleeding or oozing following an injury, surgery, or having a tooth pulled.
In severe cases of hemophilia, continuous bleeding occurs after minor trauma or even in the absence of
injury (spontaneous bleeding). Serious complications can result from bleeding into the joints, muscles,
brain, or other internal organs. Milder forms of hemophilia do not necessarily involve spontaneous
bleeding, and the condition may not become apparent until abnormal bleeding occurs following surgery
or a serious injury.Hemophilia occurs much more commonly in males than in females. About 1 in 4,000
to 1 in 5,000 males worldwide are born with this disorder. Hemophilia is inherited in an X-linked
recessive pattern.
Rhonda does not have Hemophilia. However, Rhonda’s father, George, did have Hemophilia.
Rhonda’s mother, Eileen, did not have Hemophilia. Rhonda’s husband, Frank, does not have Hemophilia.
Frank’s parents, Mark and Julie, did not have Hemophilia.
Short Story 4: Hemophilia
1. In Figure 1, what is person 1’s blood genotype?
2. In Figure 1, what is person 5’s blood genotype?
3. In Figure 1, what is person 7’s blood genotype?
4. In short story 1, show by using a Punnett Square, what are the odds of Sussanah and Paul having a
child with Lynch syndrome.
5. In short story number 1, show by using a Punnett Square, what are the odds of Sussanah and Paul
having a baby girl?
6. In short story 2, how would you determine if Edgar is carrying a recessive allele for syndactyly?
7. In short story 3, show by using a Punnett Square, why are the females always red in color, but the
males always white in color?
8. In short story 4, show by using a Punnett Square, what are the odds of Rhonda and Frank having a
baby girl with Hemophilia?
9. In short story 4, show by using a Punnett Square, what are the odds of Rhonda and Frank having a
baby boy with Hemophilia?
10. A homozygous red flowering pea plant is crossed with a homozygous white flowering pea plant.
Show by using a Punnett Square, what are the odds of having a pink flowering offspring?