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CURRICULUM VITAE of Masahiro Hiraoka Professional experiences 1977-1978 1978-1979 1979-1980 1984-1987 1987-1988 1988-1989 1989-1991 1992-1995 1995-present 2006-2010 2007-2009 2008-2013 2012-present Resident at Department of Radiology, Faculty of Medicine, Kyoto University Resident at Division of Radiation Oncology, Department of Radiology, Kawasaki Medical University Clinical staff at Division of Radiation Oncology, Department of Radiology, Kawasaki Medical University Assistant Professor, Department of Radiology, Faculty of Medicine, Kyoto University Visiting Assistant Professor, Department of Radiation Oncology, Stanford University Assistant Professor, Department of Radiology, Faculty of Medicine, Kyoto University Instructor, Department of Radiology, Faculty of Medicine, Kyoto University Associate Professor, Department of Radiology, Faculty of Medicine, Kyoto University Professor and Chairman, Department of Radiation Oncology & Image-applied Therapy, Kyoto University Graduate School of Medicine Director, Kyoto University Nanomedicine Merger Education Unit Director, Kyoto University Hospital Cancer Center Deputy Dean, Kyoto University Graduate School of Medicine Vice-director, Socio-academic collaboration office of Kyoto University Academic society activities President Federation of Asian Organizations for Radiation Oncology (FARO) Japanese Board of Cancer Therapy Japanese Society of Radiation Oncology Vice-president 1 Asian Society of Hyperthermic Oncology Executive Board members The Japanese Association for Molecular Targeting Therapy of Cancer Japanese Society of Molecular Imaging Japan Society of Breast Cancer Japan radiological Society Editor-in-Chief International Journal of Clinical Oncology Breast Cancer Associate Editor Cancer Science Awards 2008 Award of Minister of Economy, Trade and Industry for “Development of High-precision Radiotherapy System” 2008 An Award of Japan Society of Mechanical Engineering 2009 Prize of Komei-Nakayama Award of Japan Society of Clinical Oncology 2013 Prizes for Science and Technology of the Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology. Publication (2013-present) Hamaji M, Chen F, Matsuo Y, Ueki N, Hiraoka M, Date H. Treatment and prognosis of isolated local relapse after stereotactic body radiotherapy for clinical stage I non-small cell lung cancer: importance of salvage surgery. J Thorac Oncol. 2015 Aug 26. Onimaru R, Shirato H, Shibata T, Hiraoka M, Ishikura S, Karasawa K, Matsuo Y, Kokubo M, Shioyama Y, Matsushita H, Ito Y, Onishi H. Phase I study of stereotactic body radiation therapy for peripheral T2N0M0 non-small cell lung cancer with PTV<100cc using a continual reassessment method (JCOG0702). Radiother Oncol. 2015 Jul 29. pii: S0167-8140(15)00360-6. 2 Hirata K, Nakamura M, Yoshimura M, Mukumoto N, Nakata M, Ito H, Inokuchi H, Matsuo Y, Mizowaki T, Hiraoka M. Dosimetric evaluation of the Acuros XB algorithm for a 4MV photon beam in head and neck intensity-modulated radiation therapy. J Appl Clin Med Phys. 2015 Jul 8;16(4):5222. Tanaka S, Harada H, Hiraoka M. A novel method to visually determine the intracellular pH of xenografted tumor in vivo by utilizing fluorescent protein as an indicator. Biochem Biophys Res Commun. 2015 Sep 4;464(4):1151-6. Nakamura M, Takamiya M, Akimoto M, Ueki N, Yamada M, Tanabe H, Mukumoto N, Yokota K, Matsuo Y, Mizowaki T, Kokubo M, Hiraoka M. Target localization errors from fiducial markers implanted around a lung tumor for dynamic tumor tracking. Phys Med. 2015 Jul 9. pii: S1120-1797(15)00152-0. Inokuchi H, Mizowaki T, Norihisa Y, Takayama K, Ikeda I, Nakamura K, Nakamura M, Hiraoka M. Clinical effect of multileaf collimator width on the incidence of late rectal bleeding after high-dose intensity-modulated radiotherapy for localized prostate carcinoma. Int J Clin Oncol. 2015 Jul 12. [Epub ahead of print] Mizowaki T, Norihisa Y, Takayama K, Ikeda I, Inokuchi H, Nakamura K, Kamba T, Inoue T, Kamoto T, Ogawa O, Hiraoka M. Long-term outcomes of intensity-modulated radiation therapy combined with neoadjuvant androgen deprivation therapy under an early salvage policy for patients with T3-T4N0M0 prostate cancer. Int J Clin Oncol. 2015 Jul 4. [Epub ahead of print] Nakamura M, Akimoto M, Ono T, Nakamura A, Yano S, Nakata M, Itasaka S, Mizowaki T, Shibuya K, Hiraoka M. Interfraction positional variation in pancreatic tumors using daily breath-hold cone-beam computed tomography with visual feedback. J Appl Clin Med Phys. 2015 Mar 8;16(2):5123. Sato S, Miyabe Y, Takahashi K, Yamada M, Nakamura M, Ishihara Y, Yokota K, Kaneko S, Mizowaki T, Monzen H, Hiraoka M. Commissioning and quality assurance of Dynamic WaveArc irradiation. J Appl Clin Med Phys. 2015 Mar 8;16(2):5080. Akimoto M, Nakamura M, Mukumoto N, Yamada M, Tanabe H, Ueki N, Kaneko S, Matsuo Y, Mizowaki T, Kokubo M, Hiraoka M. Baseline correction of a correlation model for 3 improving the prediction accuracy of infrared marker-based dynamic tumor tracking. J Appl Clin Med Phys. 2015 Mar 8;16(2):4896. Kishi T, Matsuo Y, Ueki N, Iizuka Y, Nakamura A, Sakanaka K, Mizowaki T, Hiraoka M. Pretreatment Modified Glasgow Prognostic Score Predicts Clinical Outcomes After Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer. Int J Radiat Oncol Biol Phys. 2015 Jul 1;92(3):619-26. Ikeda I, Mizowaki T, Ono T, Yamada M, Nakamura M, Monzen H, Yano S, Hiraoka M. Effect of intrafractional prostate motion on simultaneous boost intensity-modulated radiotherapy to the prostate: A simulation study based on intrafractional motion in the prone position. Med Dosim. 2015 May 19. pii: S0958-3947(15)00036-9. Matsuo Y, Verellen D, Poels K, Mukumoto N, Depuydt T, Akimoto M, Nakamura M, Ueki N, Engels B, Collen C, Kokubo M, Hiraoka M, de Ridder M. A multi-centre analysis of treatment procedures and error components in dynamic tumour tracking radiotherapy. Radiother Oncol. 2015 Jun;115(3):412-8. Burghelea M, Verellen D, Poels K, Gevaert T, Depuydt T, Tournel K, Hung C, Simon V, Hiraoka M, de Ridder M. Geometric Verification of Dynamic Wave Arc Delivery With the Vero System Using Orthogonal X-ray Fluoroscopic Imaging. Int J Radiat Oncol Biol Phys. 2015 Jul 15;92(4):754-61. Yamamoto M, Hokugo A, Takahashi Y, Nakano T, Hiraoka M, Tabata Y. Combination of BMP-2-releasing gelatin/β-TCP sponges with autologous bone marrow for bone regeneration of X-ray-irradiated rabbit ulnar defects. Biomaterials. 2015 Jul;56:18-25. Inoue M, Yoshimura M, Sato S, Nakamura M, Yamada M, Hirata K, Sasaki M, Fujimoto T, Ogura M, Hiraoka M. Improvement of registration accuracy in accelerated partial breast irradiation using the point-based rigid-body registration algorithm for patients with implanted fiducial markers. Med Phys. 2015 Apr;42(4):1904-10. Gaowa A, Horibe T, Kohno M, Tabata Y, Harada H, Hiraoka M, Kawakami K. Enhancement of anti-tumor activity of hybrid peptide in conjugation with carboxymethyl dextran via disulfide linkers. Eur J Pharm Biopharm. 2015 May;92:228-36. 4 Hamaji M, Chen F, Matsuo Y, Kawaguchi A, Morita S, Ueki N, Sonobe M, Nagata Y, Hiraoka M, Date H. Video-assisted thoracoscopic lobectomy versus stereotactic radiotherapy for stage I lung cancer. Ann Thorac Surg. 2015 Apr;99(4):1122-9. Hatanaka S, Miyabe Y, Tohyama N, Kumazaki Y, Kurooka M, Okamoto H, Tachibana H, Kito S, Wakita A, Ohotomo Y, Ikagawa H, Ishikura S, Nozaki M, Kagami Y, Hiraoka M, Nishio T. Dose calculation accuracies in whole breast radiotherapy treatment planning: a multi-institutional study. Radiol Phys Technol. 2015 Jul;8(2):200-8. Nakamura M, Akimoto M, Mukumoto N, Yamada M, Tanabe H, Ueki N, Matsuo Y, Mizowaki T, Kokubo M, Hiraoka M. Influence of the correlation modeling period on the prediction accuracy of infrared marker-based dynamic tumor tracking using a gimbaled X-ray head. Phys Med. 2015 May;31(3):204-9. Goto Y, Zeng L, Yeom CJ, Zhu Y, Morinibu A, Shinomiya K, Kobayashi M, Hirota K, Itasaka S, Yoshimura M, Tanimoto K, Torii M, Sowa T, Menju T, Sonobe M, Kakeya H, Toi M, Date H, Hammond EM, Hiraoka M, Harada H. UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α. Nat Commun. 2015 Jan 23;6:6153. Hiraoka M, Inokuchi H. [Recent progress in radiation therapy]. Gan To Kagaku Ryoho. 2014 Dec;41(13):2535-8. Review. Japanese. Ishihara Y, Sawada A, Nakamura M, Miyabe Y, Tanabe H, Kaneko S, Takayama K, Mizowaki T, Kokubo M, Hiraoka M. Development of a dose verification system for Vero4DRT using Monte Carlo method. J Appl Clin Med Phys. 2014 Nov 8;15(6):4961. Kodaira T, Nishimura Y, Kagami Y, Ito Y, Shikama N, Ishikura S, Hiraoka M. Definitive radiotherapy for head and neck squamous cell carcinoma: update and perspectives on the basis of EBM. Jpn J Clin Oncol. 2015 Mar;45(3):235-43. Nakajima A, Endo H, Okuyama H, Kiyohara Y, Kimura T, Kamiura S, Hiraoka M, Inoue M. Radiation sensitivity assay with a panel of patient-derived spheroids of small cell carcinoma of the cervix. Int J Cancer. 2015 Jun 15;136(12):2949-60. Ueki N, Matsuo Y, Togashi Y, Kubo T, Shibuya K, Iizuka Y, Mizowaki T, Togashi K, 5 Mishima M, Hiraoka M. Impact of pretreatment interstitial lung disease on radiation pneumonitis and survival after stereotactic body radiation therapy for lung cancer. J Thorac Oncol. 2015 Jan;10(1):116-25. Iizuka Y, Yoshimura M, Inokuchi H, Matsuo Y, Nakamura A, Mizowaki T, Hirano S, Kitamura M, Tateya I, Hiraoka M. Recurrence patterns after postoperative radiotherapy for squamous cell carcinoma of the pharynx and larynx. Acta Otolaryngol. 2015 Jan;135(1):96-102. Ono T, Miyabe Y, Yamada M, Yokota K, Kaneko S, Sawada A, Monzen H, Mizowaki T, Kokubo M, Hiraoka M. Development of an expanded-field irradiation technique using a gimbaled x-ray head. Med Phys. 2014 Oct;41(10):101706. Matsuo Y, Chen F, Hamaji M, Kawaguchi A, Ueki N, Nagata Y, Sonobe M, Morita S, Date H, Hiraoka M. Comparison of long-term survival outcomes between stereotactic body radiotherapy and sublobar resection for stage I non-small-cell lung cancer in patients at high risk for lobectomy: A propensity score matching analysis. Eur J Cancer. 2014 Nov;50(17):2932-8. Iizuka Y, Matsuo Y, Umeoka S, Nakamoto Y, Ueki N, Mizowaki T, Togashi K, Hiraoka M. Prediction of clinical outcome after stereotactic body radiotherapy for non-small cell lung cancer using diffusion-weighted MRI and (18)F-FDG PET. Eur J Radiol. 2014 Nov;83(11):2087-92. Matsuo Y, Ueki N, Takayama K, Nakamura M, Miyabe Y, Ishihara Y, Mukumoto N, Yano S, Tanabe H, Kaneko S, Mizowaki T, Monzen H, Sawada A, Kokubo M, Hiraoka M. Evaluation of dynamic tumour tracking radiotherapy with real-time monitoring for lung tumours using a gimbal mounted linac. Radiother Oncol. 2014 Sep;112(3):360-4. Tsuruta Y, Nakata M, Nakamura M, Matsuo Y, Higashimura K, Monzen H, Mizowaki T, Hiraoka M. Dosimetric comparison of Acuros XB, AAA, and XVMC in stereotactic body radiotherapy for lung cancer. Med Phys. 2014 Aug;41(8):081715. Fujimoto T, Monzen H, Nakata M, Okada T, Yano S, Takakura T, Kuwahara J, Sasaki M, Higashimura K, Hiraoka M. Dosimetric shield evaluation with tungsten sheet in 4, 6, and 9MeV electron beams. Phys Med. 2014 Nov;30(7):838-42. 6 Koubuchi S, Takakura T, Nakamura M, Mizowaki T, Nakata M, Hiraoka M. Accuracy of positional correction for the floor-mounted kV X-ray IGRT system in angled couch positions. Radiol Phys Technol. 2014 Jul;7(2):373-8. Shiinoki T, Sawada A, Ishihara Y, Miyabe Y, Matsuo Y, Mizowaki T, Kokubo M, Hiraoka M. Dosimetric impact of gold markers implanted closely to lung tumors: a Monte Carlo simulation. J Appl Clin Med Phys. 2014 May 8;15(3):4594. Sasaki M, Nakata M, Inoue M, Sato S, Nakamura M, Fujimoto T, Tsuruta Y, Yano S, Higashimura K, Yoshimura M, Hiraoka M. [Use of surgical clips to verify positional accuracy in image-guided accelerated partial breast irradiation].Nihon Hoshasen Gijutsu Gakkai Zasshi. 2014 May;70(5):467-75. Japanese. Mampuya WA, Matsuo Y, Ueki N, Nakamura M, Mukumoto N, Nakamura A, Iizuka Y, Kishi T, Mizowaki T, Hiraoka M. The impact of abdominal compression on outcome in patients treated with stereotactic body radiotherapy for primary lung cancer. J Radiat Res. 2014 Sep;55(5):934-9. Mukumoto N, Nakamura M, Yamada M, Takahashi K, Tanabe H, Yano S, Miyabe Y, Ueki N, Kaneko S, Matsuo Y, Mizowaki T, Sawada A, Kokubo M, Hiraoka M. Intrafractional tracking accuracy in infrared marker-based hybrid dynamic tumour-tracking irradiation with a gimballed linac. Radiother Oncol. 2014 May;111(2):301-5. Miki K, Hashimoto H, Inoue T, Matsuoka H, Harada H, Hiraoka M, Ohe K. Sonication-induced formation of size-controlled self-assemblies of amphiphilic Janus-type polymers as optical tumor-imaging agents. Small. 2014 Aug;10(15):3119-30. Ogura K, Mizowaki T, Ishida Y, Hiraoka M. Dosimetric advantages of O-ring design radiotherapy system for skull-base tumors. J Appl Clin Med Phys. 2014 Mar 6;15(2):4608. Watanabe T, Mizowaki T, Arakawa Y, Iizuka Y, Ogura K, Sakanaka K, Miyamoto S, Hiraoka M. Pineal parenchymal tumor of intermediate differentiation: Treatment outcomes of five cases. Mol Clin Oncol. 2014 Mar;2(2):197-202. Epub 2013 Dec 23. Sato M, Hiraoka M, Suzuki H, Sakima M, Mamun AA, Yamane Y, Fujita T, Yokoyama U, 7 Okumura S, Ishikawa Y. Protection of cardiomyocytes from the hypoxia-mediated injury by a peptide targeting the activator of G-protein signaling 8. PLoS One. 2014 Mar 14;9(3):e91980. Nakamura A, Itasaka S, Takaori K, Kawaguchi Y, Shibuya K, Yoshimura M, Matsuo Y, Mizowaki T, Uemoto S, Hiraoka M. Radiotherapy for patients with isolated local recurrence of primary resected pancreatic cancer. Prolonged disease-free interval associated with favorable prognosis. Strahlenther Onkol. 2014 May;190(5):485-90. Ono T, Miyabe Y, Yamada M, Shiinoki T, Sawada A, Kaneko S, Monzen H, Mizowaki T, Kokubo M, Hiraoka M. Geometric and dosimetric accuracy of dynamic tumor-tracking conformal arc irradiation with a gimbaled x-ray head. Med Phys. 2014 Mar;41(3):031705. Ueki N, Matsuo Y, Nakamura M, Mukumoto N, Iizuka Y, Miyabe Y, Sawada A, Mizowaki T, Kokubo M, Hiraoka M. Intra- and interfractional variations in geometric arrangement between lung tumours and implanted markers. Radiother Oncol. 2014 Mar;110(3):523-8. Ogura K, Mizowaki T, Arakawa Y, Ogura M, Sakanaka K, Miyamoto S, Hiraoka M. Initial and cumulative recurrence patterns of glioblastoma after temozolomide-based chemoradiotherapy and salvage treatment: a retrospective cohort study in a single institution. Radiat Oncol. 2013 Apr 23;8:97. Zhao T, Zhu Y, Morinibu A, Kobayashi M, Shinomiya K, Itasaka S, Yoshimura M, Guo G, Hiraoka M, Harada H. HIF-1-mediated metabolic reprogramming reduces ROS levels and facilitates the metastatic colonization of cancers in lungs. Sci Rep. 2014 Jan 23;4:3793. Ogura K, Mizowaki T, Arakawa Y, Sakanaka K, Miyamoto S, Hiraoka M. Efficacy of salvage stereotactic radiotherapy for recurrent glioma: impact of tumor morphology and method of target delineation on local control. Cancer Med. 2013 Dec;2(6):942-9. Nishio T, Shirato H, Ishikawa M, Miyabe Y, Kito S, Narita Y, Onimaru R, Ishikura S, Ito Y, Hiraoka M. Design, development of water tank-type lung phantom and dosimetric verification in institutions participating in a phase I study of stereotactic body radiation therapy in patients with T2N0M0 non-small cell lung cancer: Japan Clinical Oncology Group trial (JCOG0702). J Radiat Res. 2014 May;55(3):600-7. 8 Ikeda I, Mizowaki T, Norihisa Y, Takayama K, Kamba T, Inoue T, Nakamura E, Kamoto T, Ogawa O, Hiraoka M. Long-term outcomes of dynamic conformal arc irradiation combined with neoadjuvant hormonal therapy in Japanese patients with T1c-T2N0M0 prostate cancer: case series study. Jpn J Clin Oncol. 2014 Feb;44(2):180-5. Gaowa A, Horibe T, Kohno M, Sato K, arada H, Hiraoka M, Tabata Y, Kawakami K. Combination of hybrid peptide with biodegradable gelatin hydrogel for controlled release and enhancement of anti-tumor activity in vivo. J Control Release. 2014 Feb 28;176:1-7. Sakanaka K, Matsuo Y, Nagata Y, Maki S, Shibuya K, Norihisa Y, Narabayashi M, Ueki N, Mizowaki T, Hiraoka M. Safety and effectiveness of stereotactic body radiotherapy for a clinically diagnosed primary stage I lung cancer without pathological confirmation. Int J Clin Oncol. 2014 Oct;19(5):814-21. Igaki H, Onishi H, Nakagawa K, Dokiya T, Nemoto K, Shigematsu N, Nishimura Y, Hiraoka M; Japanese Society for Therapeutic Radiology and Oncology Health Insurance Committee. A newly introduced comprehensive consultation fee in the national health insurance system in Japan: a promotive effect of multidisciplinary medical care in the field of radiation oncology--results from a questionnaire survey. Jpn J Clin Oncol. 2013 Dec;43(12):1233-7. Nakamura M, Sawada A, Mukumoto N, Takahashi K, Mizowaki T, Kokubo M, Hiraoka Effect of audio instruction on tracking errors using a four-dimensional image-guided radiotherapy system. J Appl Clin Med Phys. 2013 Sep 6;14(5):255-64. M. Takakura T, Nakamura M, Shibuya K, Nakata M, Nakamura A, Matsuo Y, Shiinoki T, Higashimura K, Teshima T, Hiraoka M. Effects of interportal error on dose distribution in patients undergoing breath-holding intensity-modulated radiotherapy for pancreatic cancer: evaluation of a new treatment planning method. J Appl Clin Med Phys. 2013 Sep 6;14(5):43-51. Mampuya WA, Nakamura M, Matsuo Y, Ueki N, Iizuka Y, Fujimoto T, Yano S, Monzen H, Mizowaki T, Hiraoka M. Interfraction variation in lung tumor position with abdominal compression during stereotactic body radiotherapy. Med Phys. 2013 Sep;40(9):091718. Akimoto M, Nakamura M, Mukumoto N, Tanabe H, Yamada M, Matsuo Y, Monzen H, 9 Mizowaki T, Kokubo M, Hiraoka M. Predictive uncertainty in infrared marker-based dynamic tumor tracking with Vero4DRT. Med Phys. 2013 Sep;40(9):091705. Kita Y, Imamura M, Mizowaki T, Norihisa Y, Yoshimura K, Hiraoka M, Ogawa O. Late recurrence of nonseminomatous germ cell tumor successfully treated with intensity-modulated radiation therapy. Jpn J Clin Oncol. 2013 Aug;43(8):835-7. Ikeda I, Mizowaki T, Sawada Y, Nakata M, Norihisa Y, Ogura M, Hiraoka M. Assessment of interfractional prostate motion in patients immobilized in the prone position using a thermoplastic shell. J Radiat Res. 2014 Jan 1;55(1):168-74. Kasuya G, Toita T, Furutani K, Kodaira T, Ohno T, Kaneyasu Y, Yoshimura R, Uno T, Yogi A, Ishikura S, Hiraoka M. Distribution patterns of metastatic pelvic lymph nodes assessed by CT/MRI in patients with uterine cervical cancer. Radiat Oncol. 2013 Jun 8;8:139. Fukui N, Kageyama Y, Higashi Y, Kihara K, Kizaka-Kondoh S, Hiraoka M, Shinojima T, Suzuki K, Oya M. Development of a novel interferon-α2b gene construct with a repetitive hypoxia-inducible factor binding site and its suppressive effects on human renal cell carcinoma cell lines in vitro. Int J Clin Oncol. 2014;19(3):497-504. Iwata H, Masuda N, Ohno S, Rai Y, Sato Y, Ohsumi S, Hashigaki S, Nishizawa Y, Hiraoka M, Morimoto T, Sasano H, Saeki T, Noguchi S. A randomized, double-blind, controlled study of exemestane versus anastrozole for the first-line treatment of postmenopausal Japanese women with hormone-receptor-positive advanced breast cancer. Breast Cancer Res Treat. 2013 Jun;139(2):441-51. Fujita M, Sasanuma H, Yamamoto KN, Harada H, Kurosawa A, Adachi N, Omura M, Hiraoka M, Takeda S, Hirota K. Interference in DNA replication can cause mitotic chromosomal breakage unassociated with double-strand breaks. PLoS One. 2013;8(4):e60043. Mukumoto N, Nakamura M, Sawada A, Suzuki Y, Takahashi K, Miyabe Y, Kaneko S, Mizowaki T, Kokubo M, Hiraoka M. Accuracy verification of infrared marker-based dynamic tumor-tracking irradiation using the gimbaled x-ray head of the Vero4DRT (MHI-TM2000). Med Phys. 2013 Apr;40(4):041706. 10 Sakanaka K, Mizowaki T, Sato S, Ogura K, Hiraoka M. Volumetric-modulated arc therapy vs conventional fixed-field intensity-modulated radiotherapy in a whole-ventricular irradiation: a planning comparison study. Med Dosim. 2013 Summer;38(2):204-8. Yoshimura M, Itasaka S, Harada H, Hiraoka M. Microenvironment and radiation therapy. Biomed Res Int. 2013;2013:685308. Nakamura A, Shibuya K, Nakamura M, Matsuo Y, Shiinoki T, Nakata M, Mizowaki T, Hiraoka M. Interfractional dose variations in the stomach and the bowels during breathhold intensity-modulated radiotherapy for pancreatic cancer: Implications for a dose-escalation strategy. Med Phys. 2013 Feb;40(2):021701. Watanabe T, Monzen H, Hara M, Mizowaki T, Hiraoka M. Pharmacokinetic model of myocardial (99m)Tc-sestamibi washout. Ann Nucl Med. 2013 Apr;27(3):279-84. Kinoshita H, Shimizu Y, Mizowaki T, Takayama K, Norihisa Y, Kamoto T, Kamba T, Hayashino Y, Hiraoka M, Ogawa O. Risk factors predicting the outcome of salvage radiotherapy in patients with biochemical recurrence after radical prostatectomy. Int J Urol. 2013 Aug;20(8):806-11. Matsugi K, Nakamura M, Miyabe Y, Yamauchi C, Matsuo Y, Mizowaki T, Hiraoka M. Evaluation of 4D dose to a moving target with Monte Carlo dose calculation in stereotactic body radiotherapy for lung cancer. Radiol Phys Technol. 2013 Jan;6(1):233-40. Mampuya WA, Matsuo Y, Nakamura A, Nakamura M, Mukumoto N, Miyabe Y, Narabayashi M, Sakanaka K, Mizowaki T, Hiraoka M. Differences in dose-volumetric data between the analytical anisotropic algorithm and the x-ray voxel Monte Carlo algorithm in stereotactic body radiation therapy for lung cancer. Med Dosim. 2013 Spring;38(1):95-9. Matsuo Y, Onishi H, Nakagawa K, Nakamura M, Ariji T, Kumazaki Y, Shimbo M, Tohyama N, Nishio T, Okumura M, Shirato H, Hiraoka M; Japan Conformal External Beam Radiotherapy Group; Japan Society of Medical Physics; Japan Society of Medical Physics; Japanese Society of Radiological Technology. Guidelines for respiratory motion management in radiation therapy. J Radiat Res. 2013 May;54(3):561-8. Utsunomiya S, Monzen H, Akimoto M, Mukumoto N, Ishihara Y, Shiinoki T, Nakamura M, 11 Miyabe Y, Sato S, Matsuo S, Hiraoka M. A feasibility study on reduction of the entrance-surface dose to neonates by use of a new digital mobile X-ray system. Radiol Phys Technol. 2013 Jan;6(1):157-61. Ueki N, Matsuo Y, Shibuya K, Nakamura M, Narabayashi M, Sakanaka K, Norihisa Y, Mizowaki T, Hiraoka M. Differences in the dose-volume metrics with heterogeneity correction status and its influence on local control in stereotactic body radiation therapy for lung cancer. J Radiat Res. 2013 Mar 1;54(2):337-43. Mizowaki T, Takayama K, Nagano K, Miyabe Y, Matsuo Y, Kaneko S, Kokubo M, Hiraoka M. Feasibility evaluation of a new irradiation technique: three-dimensional unicursal irradiation with the Vero4DRT (MHI-TM2000). J Radiat Res. 2013 Mar 1;54(2):330-6. 12