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B3: 7 Comorbidity HO3 GP Drug & Alcohol Supplement No.11 January 1999 Management of Concurrent Mental Health and Drug and Alcohol Problems Martin Evans and Katie Willey Introduction The management of mentally ill patients who misuse alcohol and other drugs creates significant challenges for general practitioners. Although not ideal, the term ‘dual diagnosis’ is used in this supplement to indicate that a patient has a mental illness and a co-existing, problematic substance use condition. Information from the Burdekin Report (1993) indicates that there is a notable lack of communication between health practitioners and services resulting in many individuals with a dual diagnosis falling through gaps in the health care system. An integrated approach, which involves a range of health providers, including professionals with mental health and drug and alcohol expertise, is required for these patients. Prevalence Rates High proportions of individuals with a mental illness are known to abuse alcohol and other drugs. According to prevalence figures from a major US study (Regier et al. 1990): 29% of all persons with a serious mental illness also had a problem with substance abuse (twice the population risk for alcohol and four times that for other drugs). 47% of persons with schizophrenia also had a problem with substance abuse (three times the population risks for alcohol and six times that for other drugs). 56% of persons with bipolar disorder also had a problem with substance abuse (eleven times the population risk for both alcohol and other drugs). 47% of persons with an alcohol disorder had a comorbid mental illness (twice the risk for the general population). 53% of persons with another drug disorder had a co-morbid mental illness (four times the risk for the general population). It was also concluded that people with mental disorders are two to six times more likely to develop substance abuse than the other way round. There have been few Australian studies on the prevalence of persons with the dual diagnosis of mental illness and alcohol and drug misuse. A study of acute psychiatric admissions to Rozelle Hospital, Sydney found that 60% had a current diagnosis of substance abuse and 66% had at least one such lifetime diagnosis of substance abuse (Cheung 1991). Information from a 1991/2 census of NSW community mental health agencies indicated that 35% of patients had a dual diagnosis (Muir et al. in press). A recent study of community health services on the Central Coast estimated that 1 in 3 patients seen had a dual diagnosis (Evans 1996). Problems associated with dual diagnosis The problems associated with substance abuse can have a devastating effect on the life of a person with a mental illness and their family. Common problems as discussed by McDermott and Pyett (1993) are: Precipitation or exacerbation of symptoms of mental illness; Reduction or exaggeration of the effects of medication; Self medication for symptoms of mental illness; Impulsive, aggressive or disinhibited behaviour; Increased attempts; Physical health deterioration; Lack of compliance with treatment; Increased frequency of relapse, acute psychiatric intervention and hospitalisation; Homelessness; Legal, financial, social and daily living problems. anxiety, depression and suicide Some groups are thought to be particularly at risk as a result of dual diagnosis and require specific approaches and interventions to be made (Burkstein et al. 1989; McDermott & Pyett 1993). These special groups are youth, women, aboriginal and homeless persons. Central Coast Area Health Service GP Drug & Alcohol Supplement No. 11 Treatment approaches Although there is considerable literature about dual diagnosis, there is limited information about best practice and practical guidelines for interventions. The integrated approach to dual diagnosis treatment combines mental health and drug and alcohol interventions in a concurrent, unified treatment program. There is considerable support for the integrated approach (Minkhoff 1991; McKelvey et al. 1989). Clenaghan et al. (1996) recommend “cross sector collaboration by way of formal and informal structures and networks to develop frameworks for service delivery with likely outcomes being the evolution of training initiatives and service development.” Systematic screening of patients for both disorders and developing links between service providers for purposes of specialist referral or conjoint management are recommended. The harm minimisation approach to dual diagnosis is also strongly recommended and supported by McDermott & Pyett (1993) and Clenaghan et al. (1996). This approach is practised widely by drug and alcohol services but less so by mental health services. Harm minimisation is a patient-centred approach which aims to reduce specific harms associated with dual diagnosis, such as homelessness, self medication and health problems, by specific matched interventions. It is recognised that in many cases abstinence from drugs may not be a realistic goal and, in these cases, a number of non-abstinence treatment goals are required. January 1999 General practitioners’ roles in the care of these patients include: 1. Identification 2. Accurate diagnosis 3. Coordination of care 4. Provision of interventions 5. Follow-up and monitoring 6. Early response to deterioration in the patient’s clinical condition 1. Identification of dual diagnosis Familiarity with the indicators of dual diagnosis and the ability to identify signs and symptoms of both mental illness and drug and alcohol conditions are the keys to identifying a person with dual diagnosis. Carr (1997) states that detection of substance use in a person with schizophrenia is the first priority. Undetected substance use may be one of the reasons patients respond poorly to treatment. Carr (1997) also states that it is important to acknowledge the reasons the person is using other substances particularly if use helps relieve distress. Addressing the ‘margin of safety’ between the adverse effects and desired effects in all types of drugs both prescribed and recreational is necessary. Abstinence should be advocated as the safest option but a harm minimisation approach can be used as a satisfactory compromise. Short-term goals such as controlled and safe use and relapse prevention skills should also be discussed with the patient and if necessary, interpersonal and social problems should be addressed. Practical approaches when working with dual diagnosis patients Indicators of dual alcohol assessment Engagement and persuasion strategies have been shown to be particularly useful in the initial contact with patients who have a dual diagnosis. Engagement refers to the initial development of a trusting relationship between patient and service provider. Persuasion refers to the process by which patients learn how substance use affects their lives and develop motivation to change (Osher & Kofoed 1989). Other approaches that have been recommended by Clenaghan et al. (1996) as guidelines for the management of dual diagnosis include: Assertive outreach interventions and close monitoring of patients; A comprehensive and holistic approach so that the varied, associated problems can be addressed by a range of strategies; A longitudinal perspective to treatment, which should occur continuously over years rather than sporadically or during crises. A detailed account of a drug and alcohol assessment is outlined in a previous supplement (No. 3 Assessment and Treatment of Alcohol Problems in the General Practice Setting). In summary, a drug and alcohol assessment involves: establishing current level of use, often using a retrospective timeline which is taken by starting with the last time a person used alcohol or other drugs and enquire back through that day and then to the day before and so on for seven days. The patient is then asked if this is a typical week. taking a lifetime history of use through enquiring about age at onset of regular use, changes in use over time, periods of abstinence and problems with withdrawal. assessing problems related to alcohol and other drug use through pharmacological knowledge and through report from the patient about problems related to health, relationships and sexual behaviour, work, accidents, and problems of dependence. This includes narrowing of drinking repertoire (type, time, amount of use becomes more stereotyped), salience of drinking (primacy over other activities), subjective awareness of compulsion to drink, increased tolerance to alcohol, repeat withdrawal symptoms, relief or avoidance of withdrawal symptoms by further drinking and reinstatement after abstinence. Primary care for dual diagnosis patients Managing a patient with concurrent mental health and alcohol or other drug problems can be difficult due to the complexity of clinical and social problems these patients can experience. General practitioners play a critical role as the primary carer in the ongoing management and continuity of care for dual diagnosis patients. Central Coast Area Health Service diagnosis: Drug and GP Drug & Alcohol Supplement No. 11 Indicators of dual diagnosis: Mental health assessment A comprehensive mental health assessment is lengthy and involves, among other things, taking a psychiatric history, history of current problem, family psychiatric history and details of relevant medical conditions. The mental state examination (MSE) is a useful tool in assessing current mental state (Leon, Bowden & Faber 1989). The MSE includes assessment of: Appearance - does the patient look physically ill? Is there evidence of self-neglect? Is the patient’s dressing flamboyant or inappropriate? Is the person well groomed or unkempt? Activity - a number of overt symptoms can be observed including rigidity, anxiety, aggression, withdrawal, disinhibition, impulsivity, suspicion, shyness or timidity during the interview. Is the patient’s overt behaviour consistent with what they are saying? Does the patient make appropriate eye contact or none at all? Does the patient display slowness or retardation, overactivity, agitation, excitation, awkwardness or idiosyncratic movements or posturing and waxy flexibility? Mood and affect - mood is described as the subjective feeling state of the patient, such as elation, depression, anger, and anxiety. Variations in mood throughout the day should be noted. Affect is a transitory emotional expression at the time of interview. Affect can vary in range, intensity, stability, appropriateness and relatedness. Speech and language - it is important to examine both the form of speech and the content. What is the patient’s rate of speech? Does the patient use words in an idiosyncratic way or invent new words (neologisms)? Does speech flow normally? Is the speech pressured? Is there evidence of thought blocking, flight of ideas, evasion, loosening of associations, circumstantiality, tangentiality, perseveration, preoccupation, paucity of ideas or over abundance of ideas? Thought content - is there evidence of ruminations, obsessions, compulsions, delusional ideas, overvalued ideas, pre-occupations or phobias? Perceptual disturbances - are symptoms of illusions (misinterpreted perceptions such as seeing shadows as people), hallucinations (sensory experiences without external stimulation), depersonalisation (patient feels they have lost their personal identity), derealisation (patient feels that the environment is unreal) or formication (tactile hallucination of insects crawling under skin) present? Insight and judgment - the patient’s capacity to understand his or her symptoms as abnormal experiences and relate them to the presence of illness. Neuropsychiatric evaluation - it is important to examine cognitive functioning and check level of consciousness, attention and concentration, January 1999 language fluency, memory and higher cognitive functioning. 2. Accurate diagnosis Patients with dual mental health and drug and alcohol problems often present with unclear diagnoses, which inhibits effective treatment approaches being instituted. Patients can present with a range of signs and symptoms which need to be sorted into differential diagnoses initially, and then further investigated and clarified into a diagnosis which can guide treatment. An example would be the presence of psychotic symptoms, which may be substance induced, may be secondary to a medical condition or part of a schizophrenic illness. The appropriate treatment, which would be different with each diagnosis, will be determined by making an accurate diagnosis. Because the GP will usually have a longterm relationship with the patient, knowledge of individual patterns of mental illness can be included in making an accurate diagnosis. GPs can use this knowledge to determine the extent to which substance use or mental illnesses are the primary issues. GPs also have the capacity to investigate for causes of the problems, such as screening for presence of drugs or identifying medical conditions, which may be causative, such as intracranial hemorrhages. 3. Coordination of care Dual diagnosis patients often have multiple health and social problems, thus coordinated care which achieves the involvement of a range of relevant service providers in the management of the dual diagnosis patient is of clinical benefit. Involvement of services such as Area Mental Health and Drug and Alcohol Services either in a consultative and referral role or as collaborating service providers is usually necessary. The GP is ideally placed to be the primary carer of the patient calling on specialist services when the need arises. An example could be when the patient does not turn up for an appointment with the Mental Health Team. The patient’s GP can assess the patient and if necessary, organise urgent assertive follow up of the patient by the mental health team to gain quick, early control of the patient’s deteriorating clinical condition. General health care provided by the GP will also improve outcomes for these patients. This type of management has been advocated as a successful approach in the management of dual diagnosis. (Clenaghan et al, 1996) The support of the Area Health Service can be useful in managing this group of patients. Involvement of both Mental Health Services and Alcohol and Other Drug Services would usually be included in the management plan for a person with concurrent mental health and drug and alcohol problems. Each service can offer specialist expertise and support. The Central Coast Mental Health Service and the Alcohol and Other Drug Service are striving now to work more cooperatively together to manage patients with dual diagnoses. These services are working to Central Coast Area Health Service GP Drug & Alcohol Supplement No. 11 January 1999 more effectively treat the patients who previously fell between the gaps. that can result in high levels of distress and disruption to the patient’s life. 4. Provision of interventions 6. Early response to deterioration in the patient’s clinical condition There are a number of drug and alcohol interventions that are known to be effective, including relapse prevention strategies, controlled drinking programs and motivational interviewing (Mattick & Jarvis 1993). These interventions should also be used with patients who have dual diagnoses. Although these interventions are not likely to be effective for patients with unstable psychiatric presentations, they are appropriate for patients who have relatively stable presentations and some degree of insight. Psychosocial treatment of psychiatric conditions includes provision of education about psychiatric disorders, signs of early relapse, the benefits of treatment, and how to identify symptoms early. It also includes rehabilitation of patients through, for example, social skills and living skills training. These approaches should be applied to patients with dual drug and alcohol and mental health problems. 5. Follow-up and monitoring Close monitoring and follow-up have been advocated as one of the most effective strategies in the management of patients with dual diagnosis. They provide the opportunity to identify early any variations in mental state and degrees of substance use, and also improve compliance with psychiatric medication. They also provide continuous care for these clients in comparison to crisis driven and acute episodic care Patients will dual diagnosis often has a number of health, social and interpersonal problems exacerbated by both mental illness and substance use. Because GPs are in a position to regularly follow-up these clients they are well placed to monitor deterioration in the patient’s clinical condition. Once recognised, the GP can increase the frequency of contact, increase or change medication as required, or facilitate entry into other services before the condition worsens. Prevention of an acute episode and admission to hospital is the optimal result ensuring as little disruption to the patient’s life as possible. _________ The Mental Health Service can be contacted on 02 43 203 500 24 hours a day, 7 days a week. The Alcohol and Other Drug intake service can be contacted by patients on 02 43 202 637 between 8.00-5.00 pm on weekdays. Information and advice for GPs about the management of patients with alcohol and other drug problems can be obtained through the Drug and Alcohol Clinical Advisory Service on 0413 276 177. Please note this service is to be obtained by health professionals only. References Burdekin, B., Guilfoyle, M. & Hall, D. (1993). Human rights and mental illness. Report of the national inquiry into human rights of people with mental illness. Australian Government Publishing Service: Canberra. Burkstein, O., Brent, D. & Kaminer, Y. (1989). Co-morbidity of substance abuse and other psychiatric disorders in adolescents. American Journal of Psychiatry, 146: 1131-1141. Carr, V.J. (1997). The role of the general practitioner in the treatment of schizophrenia: specific issues. Medical Journal of Australia, 166, 3: 143-146 Cheung, R. (1991). The detection of psychoactive substance use in acute admissions : a pilot study, dissertation for R.A.N.Z.C.P. Fellowship. Clenaghan, P., Rosen, A., Van Bysterveld, M., Friel, O. & Spilsburg G. (1996). Developing effective strategies for people with a serious mental illness and problematic substance use. Royal North Shore Hospital and Community Mental Health and Drug and Alcohol Services, Sydney. Evans, M. (1996). Identifying the needs of community mental health workers in managing clients who misuse alcohol and other drugs. Central Coast Area Health Service. Hall, W. & Farrell, M. (1997). Co-morbidity between substance use and other mental disorders. National Drug and Alcohol Research Centre, Sydney. Leon, R.L., Bowden, C.L. and Faber, R.A. (1989). The psychiatric interview, history and mental state examination. In Kaplan, H.I and Sadock, B.J. (Eds) Comprehensive Textbook of Psychiatry/V, Volume 1, 5th Edition. Williams and Williams: Baltimore. Chapter 9.1. Mattick, R. & Jarvis, T. (1993). An outline for the management of alcohol problems : quality assurance project. Government Publishing Service : Canberra. Australian McDermott, F. & Pyett, P. (1995). Not welcome anywhere - people who have both a serious psychiatric disorder and problematic drug or alcohol use. Victorian Community Managed Mental Health Services: Melbourne. McKelvey, M., Kane, J. & Kellison, K. (1989). Substance abuse and mental illness. Journal of Psychosocial Nursing and Mental Health Services, 25 (1), 20-25. Minkoff, K. (1991). Program components of a comprehensive integrated care system for serious mentally ill patients with substance disorders. New Directions for Mental Health Services, 50, 13-27. Muir, C., Flaherty, B. & Ross, J. (In press). Census of community drug and alcohol clients, NSW 1991 & 1992. Drug and Alcohol Directorate, Sydney. Osher, F. & Kofoed, L. (1989). Treatment of patients with psychiatric and psychoactive substance abuse disorders. Hospital and Community Psychiatry, 40, 1925-1030. Central Coast Area Health Service GP Drug & Alcohol Supplement No. 11 January 1999 Regier, D., Farmer, M., Rae, D., Goodwin, F., Judd, L., Keith, S. & Locke, B. (1990). Co-morbidity of mental disorders with alcohol and other drug abuse - Results from the E.C.A. study. Journal of the American Medical Association, 264, 2511-2518. Central Coast Area Health Service