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Destroying Schedule 4 Controlled Drugs (CDs) It is now a legal requirement that the following Schedule 4 CDs must be denatured in a DOOP kit before being destroyed. As with other CDs they need to be destroyed by a pharmacist and nurse. Chlordiazepoxide Nitrazepam Clobazam Oxazepam Clonazepam (Potassium Chlorazepate) Diazepam (Triazolam) Loprazolam Zaleplon Lorazepam Zolpidem Lormetazepam Zopiclone This destruction must be recorded in the book specially held on the ward/team base to record the destruction or return of ‘medicines requiring additional security’. There is however an exception - any dose of a controlled drug that is prepared but not administered, including odd doses spat out by the patient must be destroyed on the ward or department immediately. Though CDs are usually destroyed in a DOOP kit, these single doses can be disposed of in the general medicines waste bin. Solid dosage forms should be wetted in a small amount of soapy water before tipping everything into the general medicines waste bin. This destruction of the controlled drug must be in the presence of a second designated practitioner or if not available another member of staff familiar with CDS, e.g. an authorized employee trained to witness the administration of CDs. The appropriate entry must be made either in the Controlled Drug Register if a full CD requiring storage in the CD cupboard or if a schedule 4 CD in the book especially held on the ward/team base. The entry must include the signatures of the two individuals involved in the destruction. Pharmacy Team September 2016