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Lab 5 ALS & Trigeminal Systems 1Marginal Zone 2Substantia gelatinosa Mid-lumbar level of spinal cord Cresyl violet stain for cell bodies (Anatomical Orientation) Ventral white 1 comissure Substantia 2 Gelatinosa (very white) Ventral white 1comissure Substantia 2 Gelatinosa (relatively white) 2 ML raphe 3 nuclei 5 ML ALS 1 ALS 4 What brainstem level is shown here? Rostral Medulla The ALS & ML labels represent sensation from which side of the body? Left 2 Medial lemniscus 1 ALS Medial 4 lemniscus ALS 3 ALS What brainstem level is shown here? Caudal Pons ALS 1 ALS Medial 2 Lemniscus Medial 5 Lemniscus ALS4 PAG 3 PAG 6 What brainstem level is shown here? Rostral Midbrain Internal medullary lamina + Intralaminar nuclei General location: Internal medullary lamina + intralaminar nuclei 1 3 Posterior 2 limb, internal capsule What is the approximate location of the: Substantia Gelatinosa? Marginal Zone? Ventral White Commisure? ALS? What spinal level is shown here? Sacral (again, probably don’t need to know) What is the approximate location of the: Substantia Gelatinosa? Marginal Zone? Ventral White Commisure? ALS? What spinal level is shown here? Lumbar What is the approximate location of the: Substantia Gelatinosa? Marginal Zone? Ventral White Commisure? ALS? What spinal level is shown here? Thoracic What is the approximate location of the: Substantia Gelatinosa? Marginal Zone? Ventral White Commisure? ALS? What spinal level is shown here? Cervical What is the approximate location of the: ALS? Reticular Formation? Poorly defined area. What brainstem level is shown here? Caudal Medulla What is the approximate location of the: ALS? Reticular Formation? What brainstem level is shown here? Mid/Rostral Medulla What is the approximate location of the: What brainstem level is shown here? ALS? Rostral Medulla Reticular Formation? Raphe Nucleus? Decending Pain Block (Serotonin or NorEp) What is the approximate location of the: ALS? Reticular Formation? Raphe Nucleus? What brainstem level is shown here? Caudal Pons What is the approximate location of the: ALS? Reticular Formation? Raphe Nucleus? What brainstem level is shown here? Rostral Pons What is the approximate location of the: ALS? Reticular Formation? Medial Lemniscus? What brainstem level is shown here? Rostral Pons What is the approximate location of the: ALS? Reticular Formation? PAG? What brainstem level is shown here? Rostral Midbrain Contains fibers from both: ALS and Medial Lemniscus What is the approximate location of the VPL? What part of the brain is shown here? Thalamus What is the approximate location of the ALS? What is the approximate location of the ALS? What is the approximate location of the ALS? What is the approximate location of the ALS? Trigeminal System C.N. V nerve roots, trigeminal nerve Medial 1 lemniscus VTTT 2 Motor (medial) 3 & main sensory (lateral) nuclei of V, separated by C.N. V nerve roots (black line) What level of the brainstem is shown here? Rostral Pons Spinal trigeminal tract 2 Spinal trigeminal 1 nucleus General position of spinal trigeminal tract (lateral) and spinal trigeminal nucleus (medial) – in lateral tegmentum What level of the brainstem is shown here? Caudal Medulla 1 POSITION OF MEDIAL LEMNISCUS (outlined in red) ALS 2 Spinal trigeminal 3 nucleus ALS 5 Spinal trigeminal 7 tract Spinal trigeminal 4 tract Spinal trigeminal 6 nucleus What level of the brainstem is shown here? Rostral Medulla Medial 2 lemniscus 1 ALS 6 Medial lemniscus ALS 5 spinal 7 trigeminal nucleus Spinal trigeminal 3 nucleus Spinal trigeminal 4 tract What level of the brainstem is shown here? Caudal Pons spinal 8 trigeminal tract ALS 1 ALS Medial 2 Lemniscus Medial 7 Lemniscus ALS5 location of 3 the VTTT PAG 4 PAG 8 location of 6 the VTTT What level of the brainstem is shown here? Rostral Midbrain Medial Lemniscus ML ML VTTT VTTT ALS ALS PAG VTTT What is the approximate location of the ML, ALS, & VTTT in the figure on the left? What is the approximate location of the ML, ALS, & VTTT in the figure on the right? Spinaltrigeminal Nucleus – sends axons that cross & accend to VPM Spinaltrigeminal tract – ipsilateral pain and temp from face and teeth What is the approximate location of the: Spinal Trigeminal Tract? Spinal Trigeminal Nucleus? What brainstem level is shown here? Caudal Medulla Axons cross and ascend in to VTTT at the caudal pons and continue to the VPM What is the approximate location of the: Spinal Trigeminal Tract? Spinal Trigeminal Nucleus? What brainstem level is shown here? Mid/Rostral Medulla What is the approximate location of the: Spinal Trigeminal Tract? Spinal Trigeminal Nucleus? What brainstem level is shown here? Rostral Medulla Trigeminal Roots Main Motor Nucleus Supplies muscles of mastication Main Sensory Nucleus Discriminative touch Receives fibes from trigem ganglion Sends axons across midline to VTTT Mixed VTTT Contralateral What is the approximate location of the: Trigeminal Main Sensory Nucleus? Trigeminal Main Motor Nucleus? VTTT? spinotrgeminal tract (Ipsilateral) What brainstem level is shown here? Rostral Pons What is the approximate location of the VTTT? What brainstem level is shown here? Rostral Midbrain VPM = sensory relay nucleus for general face sensation and for taste What is the approximate location of the: VPM? Posterior Limb of the Internal Capsule? What part of the brain is shown here? Thalamus
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