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GENERAL CERTIFICATE OF EDUCATION TYSTYSGRIF ADDYSG GYFFREDINOL 2009 – 2010 APPLIED SCIENCE SPECIMEN QUESTION PAPER SPECIMEN MARKING SCHEME GCE APPLIED SCIENCE Specimen Assessment Materials 3 Contents Page Question Paper - Unit 1 5 Mark Scheme 21 GCE APPLIED SCIENCE Specimen Assessment Materials 5 CYD-BWYLLGOR ADDYSG CYMRU Tystysgrif Addysg Gyffredinol Uwch Gyfrannol/Uwch WELSH JOINT EDUCATION COMMITTEE General Certificate of Education Advanced Subsidiary/Advanced Candidate Name Centre Number Candidate Number 0 APPLIED SCIENCE UNIT 1 SPECIMEN PAPER (1 hour 30 minutes) INSTRUCTIONS TO CANDIDATES Write your name, centre number and candidate number in the spaces at the top of this page. Answer all questions. Write your answers in the spaces provided in this booklet. INFORMATION FOR CANDIDATES Section A is based on the pre-release article (included). The number of marks is given in brackets at the end of each question or part-question. You are reminded of the need for good English and orderly presentation in your answers. You are reminded that assessment will take into account the quality of written communication used in your answers. No certificate will be awarded to a candidate detected in any unfair practice during the examination. GCE APPLIED SCIENCE Specimen Assessment Materials 6 Pre-release Article This article has been downloaded from the internet. About.com:Smoking Cessation COPD Includes Emphysema and Chronic Bronchitis Chronic Obstructive Pulmonary Disease (COPD) is a disease in which the airways and tiny air sacs inside the lungs are partially obstructed or destroyed. The result is labored breathing. There are varying degrees of this illness, and different names for them, but it all comes back to damaged airways and air sacs. This disease occurs when a person breathes in lung irritants of some kind: smoke, chemicals, pollution, dust. It makes sense then, that the most common cause of COPD is smoking. The inside of our lungs look like upside down trees, with the trunks at the top, tapering down to tiny branches at the bottom. At the ends of branches, there are many thousands of tiny round air sacs. In healthy people, the passageways to the sacs are clear and open. The sacs are bouncy and strong. When we take a breath, the sacs full up like little balloons, and deflate when we breathe out. In lungs with COPD, the airways are partially blocked, and the air sacs are floppy and out of shape. When a person breathes in, the sacs do not fill as well, and the result is shortness of breath. One or all of these things may be happening inside of the lungs: • • • • The airways and the air sacs have lost their springiness, like an old rubber band might The walls between many of the sacs have been destroyed The walls of the airways become thick from inflammation Cells in the airways are making more mucus [sputum] and the airways are getting clogged due to that. Chronic bronchitis happens when the airways are inflamed and thickened. More of the cells in the airways are making mucus, so the result is a habitual cough and difficult breathing. Emphysema is what occurs as more and more of the walls between air sacs get destroyed. Instead of having lots of little sacs, the sacs break up and what is left are fewer larger sacs. These bigger sacs have less surface area for the exchange of oxygen and carbon dioxide than the tiny ones. Poor exchange of oxygen and carbon dioxide causes shortness of breath. Often, people with COPD have both chronic bronchitis and emphysema. Most are smokers or former smokers. This is a disease that develops slowly from repeated exposure to lung irritants. Most people do not begin to show symptoms until they're 40 years of age or older. While the damage is permanent, by quitting, a person can improve how they feel, and stop further damage from happening. GCE APPLIED SCIENCE Specimen Assessment Materials 7 COPD Symptoms and Treatments Do you have Symptoms of COPD? Symptoms of COPD include: • • • • • cough sputum (mucus) production shortness of breath, especially with exercise wheezing (a whistling or rattle type noise) when you breathe in tightness in the chest If you have any of the above symptoms of COPD, it's time to see your doctor. The earlier this disease is diagnosed and treated, the better your chances are at arresting further damage. If you are diagnosed with COPD, there are different treatments available, depending on how severe your symptoms are. Treatment can and does improve quality of life for many people. While the disease is not reversible, it can be slowed and actions taken to improve breathing. The number one thing you can do to improve your condition if you haven't already is to QUIT SMOKING. If you don't, the disease will progress faster, and the treatments won't help as much as they would if you were smoke free. Treatment for COPD includes: • • • • • Bronchodilators. Short-acting bronchodilators last 4 to 6 hours with each dose and are used on an as needed basis. Long-acting bronchodilators last about 12 hours and are used daily. Because bronchodilators are inhaled, the medicine goes directly into the lungs, where it's needed. Inhaled glucocorticosteroids are steroids prescribed to some COPD patients to help reduce inflammation of the airways. A doctor may try them on a person for 6 weeks to 3 months initially to see if they are of any help. Pulmonary Rehabilitation is a program of combined exercise, disease management counselling and training to help the person become more active and do what they can to slow the progression of symptoms. Oxygen treatment is used when the patient has severe COPD symptoms, known usually at this point as emphysema. The oxygen level in the blood is too low, which leaves the person quite breathless. Inhaling oxygen will help them get enough oxygen and there will be less difficulty breathing. Depending on the need of the person, a doctor may advise using oxygen for part of the day, or all of the time. Surgery is sometimes recommended when other treatments have not provided any relief. COPD symptoms can worsen very quickly. When this happens, people may find that breathing suddenly becomes much more difficult; they may get a fever; experience more coughing and sputum that has changed colors. Be sure to get in touch with your doctor if this happens to you. GCE APPLIED SCIENCE Specimen Assessment Materials 8 If you experience any of these symptoms, seek emergency help: • • • • You have trouble talking or walking You have a very fast or irregular heartbeat Your lips or fingernails are gray or blue Your breathing is fast and hard, even after you've used your medications It's a good idea to put together a list which includes the numbers of your doctor and hospital, as well as what medications you're taking. Make sure you have the numbers of people who can take you to the doctor also, if necessary. Put this list in a central location, such as on the refrigerator. Let other family members know that it's there. COPD is the 4th leading cause of death in the United States and around the world. Material for this article was obtained from information about COPD at The National Heart, Lung and Blood Institute (NHLBI) Website. NHLBI is part of the national Institute of Health (NIH) GCE APPLIED SCIENCE Specimen Assessment Materials 9 Section A Answer all the questions These questions relate to the pre-release material. 1. 2. "Upside down trees" is the expression used in the article on COPD to describe lung structure. Replace the following words from the article with the correct biological terms. [4] Trunk ………………………….. Passageways ………………………….. tiny branches ………………………….. thousands of air sacs ………………………….. (i) What does a bronchodilator do? [1] ........................................................................................................................................... (ii) Why is this effective in helping breathing? [1] ........................................................................................................................................... .......................................................................................................................................... 3. Give four features of air sacs which make gas exchange more efficient. [4] ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... 4. Why are smokers, whose lung mucous has become thick and sticky, more likely to contract lung infections? [4] ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... GCE APPLIED SCIENCE Specimen Assessment Materials 10 5. Explain the likely cause of 'blue fingernails' in advanced COPD. [2] ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... 6. Quitting smoking is believed to lead to complete lung recovery. In what situation will this not be true? Explain why. [2] ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... 7. Describe the process of inhalation, using the following terms in the correct sequence: intercostal muscles; diaphragm; volume; pressure; ribs; pleural membranes. [8] ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... GCE APPLIED SCIENCE Specimen Assessment Materials 11 8. A decision was made not to treat a patient for COPD who had refused to quit smoking. What arguments could be used to justify this decision? [4] ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... GCE APPLIED SCIENCE Specimen Assessment Materials 12 SECTION B Answer all the questions 9. The procedures for testing blood in the hospital laboratory may involve a technician preparing a blood smear and examining it using a microscope. The photograph below shows a human blood smear. (a) (b) Identify A, B and C by giving the correct terms below. A ............................................................................. B ............................................................................. C ............................................................................. (i) What is the function of cell C? [3] [1] ......................................................................................................................................... (ii) What does cell C contain to enable it to carry out this function? [1] ................................................................... (c) The technician noticed that the cells labelled C were fewer in number than would normally be expected. What medical condition would this suggest? [1] ......................................................................................................................................... GCE APPLIED SCIENCE Specimen Assessment Materials 13 (d) Describe two hazards associated with taking a blood sample from a person. Give a control measure to minimise the risk of each. [4] ......................................................................................................................................... ......................................................................................................................................... ......................................................................................................................................... ......................................................................................................................................... 10. Complete the following statements. [2] (a) The blood leaves the heart through the ……………………….. on its way to the lungs. (b) The blood leaves the heart through the ……………………….. on its way to the rest of the body. GCE APPLIED SCIENCE Specimen Assessment Materials 14 11. The diagrams show the left side of the heart in three stages of the cardiac cycle. X and Y represent the position of valves but the drawing of them is incomplete. Key: A = left atrium V = left ventricle Atrial systole (a) Ventricular systole Ventricular diastole Give the names of the valves at X and Y. X ................................................................................. Y ................................................................................. [2] (b) Complete each diagram by drawing the valve at position X and the valve at position Y in each case showing clearly whether they are open or closed. [3] (c) Valves Y are attached to the heart wall by tendons. What is the function of these tendons? [1] ........................................................................................................................................ ........................................................................................................................................ (d) A doctor uses a stethoscope to listen to the sound of the heart beat. What is the cause of the first heart sound? [2] ........................................................................................................................... ........................................................................................................................... GCE APPLIED SCIENCE Specimen Assessment Materials 15 12. (a) Medical staff use a sphygmomanometer to measure a person's blood pressure. (i) When the nurse inflates the cuff on the person's arm, what happens to the blood flow in the artery of the arm? [1] ........................................................................................................................... (ii) What happens in the artery as the nurse slowly releases the pressure? [2] ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... (b) Blood pressure is recorded as 120/80 where the larger figure is the systolic pressure. What is systole? [1] ........................................................................................................................... (c) The diagram below shows the pressure in different vessels. (i) State why there is such a large pressure drop between the arteriole and venule. [2] ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... (ii) Calculate the percentage drop in pressure as blood flows through the capillaries. [1] Answer…………………… GCE APPLIED SCIENCE Specimen Assessment Materials 16 (d) Part of Body Blood Pressure/Kpa Standing Lying Head 9.3 13.2 Heart 13.3 13.3 Feet 26.8 13.1 Using the data and your knowledge explain why soldiers at attention on a hot parade ground sometimes faint. [4] ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... GCE APPLIED SCIENCE Specimen Assessment Materials 17 13. (a) Give two structural features which can be used to distinguish an artery from a vein. [2] ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... (b) The following diagram shows blood pressure changes as blood travels through one circuit of the circulatory system. Explain fully the reasons for the alternating high and low blood pressure in region A. [3] ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... (c) Why is it important that the blood pressure in the lung capillaries is lower than that in the body capillaries? [1] ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... GCE APPLIED SCIENCE Specimen Assessment Materials 18 14. A doctor may carry out an electrocardiogram (ECG) test which provides results as a graph trace. The diagram below shows a normal ECG trace. (a) Explain what an ECG is used for. [1] ........................................................................................................................................... ........................................................................................................................................... (b) (i) What causes P on the ECG trace? [1] ........................................................................................................................................... (ii) What causes QRST on the ECG trace? [1] ........................................................................................................................................... (c) Explain how a doctor may use a treadmill and an ECG in combination to diagnose a condition that had been indicated by a resting ECG. [4] ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... GCE APPLIED SCIENCE Specimen Assessment Materials 19 15. The picture below shows an MRI scanner being used. (a) What is an MRI scan used for? [1] ........................................................................................................................... ........................................................................................................................... (b) Give three advantages of using MRI scanning rather than X-rays. [3] ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... (c) Explain why it is important to remove items such as watches or bracelets when undergoing an MRI scan. [1] ........................................................................................................................... ........................................................................................................................... (d) Why would the images from an MRI scan involving the mouth not be clear and sharply defined. [1] ........................................................................................................................... ........................................................................................................................... GCE APPLIED SCIENCE Specimen Assessment Materials 21 STRICTLY CONFIDENTIAL WELSH JOINT EDUCATION COMMITTEE CYD-BWYLLGOR ADDYSG CYMRU MARK SCHEME COVER SHEET AS/A2 UNITS NOTES Assistants are asked to read and digest thoroughly all the information set out in the document "Instructions for Examiners". It is essential for the smooth running of the examination that these instructions are adhered to by all. Particular attention should be paid to the following instructions regarding marking: 1. The markscheme indicates the central information required to access the mark. However points, particularly in extended prose answers, should be made in the correct context and expanded sufficiently beyond a basic phrase or term in order to provide a complete and coherent answer to the question asked including relevant explanation of the points being made. 2. Compliance with the mark scheme is required of all assistants in order to ensure comparability. The mark scheme shows a variety of suitable correct answers to the questions. Over-rigidity in its interpretation is not intended and it is accepted that points may be made in a variety of different ways to include converse and counterpoints. Thus, except where terms are specifically requested, all correct responses even if expressed using different words are acceptable provided the points are explicit, unambiguous and made in the correct context. If the meaning is unclear then the mark cannot be awarded. 3. Marking is to be carried out with a red ballpoint or felt-tip pen. The ticks are to be placed on the word or phrase which qualifies for the mark. 4. Sub-totals in the margins must clearly be seen to be the sum of ticks within the script and all questions should show evidence of marking. The total for the question should be written at the end of the question. Transfer each checked total to the front cover. GCE APPLIED SCIENCE Specimen Assessment Materials 22 WELSH JOINT EDUCATION COMMITTEE CYD-BWYLLGOR ADDYSG CYMRU General Certificate of Education Tystysgrif Addysg Gyffredinol MARK SPECIFICATION GRID GCE APPLIED SCIENCE UNIT TEST Year of Examination __Specimen paper Page__1____of___2____ Session: summer/winter Unit __1_______ Assessment Objective Target Totals Question Number Section A 1 AO1 AO2 AO3 59 16 5 Paper Total Mark 80 Specification Reference 4 2 2 3 4 4 3 1 5 1 1 6 1 1 7 8 8 1 9 3 9b 2 9c 1 3 9d 30 4 10 2 11a 2 11b 1 11c 1 11d 2 12a 2 12b 1 12c 2 1 12d 3 1 10 2 2 8 1 11 GCE APPLIED SCIENCE Specimen Assessment Materials 23 WELSH JOINT EDUCATION COMMITTEE CYD-BWYLLGOR ADDYSG CYMRU General Certificate of Education Tystysgrif Addysg Gyffredinol MARK SPECIFICATION GRID GCE APPLIED SCIENCE UNIT TEST Year of Examination __________ Page___2___of__2_____ Session: summer/winter Unit ____1_____ Assessment Objective Target Totals Question Number 13a AO1 AO2 AO3 59 16 5 80 Specification Reference 2 13b 2 13c 1 14a 1 14b 2 14c 15a 1 15b 3 15c 1 15d Raw Totals: Paper Total Mark 59 1 6 4 7 1 6 17 4 80 GCE APPLIED SCIENCE Specimen Assessment Materials 24 Unit 1 Mark scheme: 1. Trachea; Bronchus/bronchi; Bronchioles; Alveoli; [1] [1] [1] [1] 2. Relaxes the muscles of the bronchioles; Reduces resistance to airflow/allows air to move more easily into alveoli. [1] [1] 3. Large surface area; rich blood supply; thin walls; moist [1] [1] [1] [1] 4. Cilia normally move mucous continuously away from lungs; thick sticky mucous difficult to move; cilia unable to function effectively; mucous traps dirt and pathogens; pathogens can cause lung infections. 4 from 5 5. Low oxygen levels in the blood; deoxygenated blood is dark red/blue/ oxygenated blood is bright red/pink. [1] [1] 6. during emphysema/ walls of alveoli have broken down; so there is permanent damage. [1] [1] 7. Intercostal muscles contract Ribs are raised upwards/outwards Diaphragm contracts/flattens Pleural membranes hold lungs to wall Volume increases Pressure decreases Air moves in Correct sequence [8] 8. smoking causes COPD; quitting smoking arrests or reverses process; treatment expensive; hospital/consultant time taken up; commitment from patient is reasonable expectation; without the commitment the treatment would be less effective; time/treatment should be given to other patients; OWTTE! Any 4. [4] GCE APPLIED SCIENCE Specimen Assessment Materials 25 Section B: 9. 10. 11. 12. (a) A white blood cell/lymphocyte B plasma C erythrocyte [1] [1] [1] (b) (i) (ii) [1] [1] (c) anaemia [1] (d) Risk of puncture wound from sharp needle so dispose of carefully in 'sharps' container. Cross contamination of blood/infection so wear protective (latex) gloves. [2] [2] (a) pulmonary artery; [1] (b) aorta; [1] (a) X= semilunar/aortic valve Y= bicuspid/atrio-ventricular/mitral valve [1] [1] (b) atrial systole- Y open X closed Ventricular systole X open Y closed Ventricular diastole Y open X closed (Valves drawn as open or closed and in correct direction) [1] [1] [1] (c) To prevent valves inverting/being forced the wrong way [1] (d) closure of the valve ref to atrioventricular [1] [1] (a) (i) blood flow stops; [1] (ii) reduces pressure and blood flow starts; at first only at systole; then normal blood flow at diastolic pressure [2] transport Contains haemoglobin (b) contraction of the ventricles (c) (i) Blood has passed through capillaries; small diameters give large resistance so large pressure drop; [2] (ii) 63% (d) [1] [1] increase blood in leg veins/veins distended; less blood to brain; venous return assisted by movement; less return(attention), hence distension; less flow to brain causes faint; pressure in the head whilst standing is lowered; data quoted . Any 4. [4] GCE APPLIED SCIENCE Specimen Assessment Materials 26 13. 14. 15. (a) Ref. to valves; size of lumen; thickness of muscle layer. Any 2. [2] (b) Contraction of ventricles causes a surge in blood pressure/ This drops when the ventricles relax/ But does not fall to zero because of the closing of the semi-lunar valves/ The elastic recoil of the arteries maintains blood pressure. Any 3. (c) (Interstitial) fluid in the lungs must not build up as this reduces the efficiency of gaseous exchange/fluid leaks out of capillaries and fills lungs. [1] (a) Measure the electrical activity in the heart over time/to diagnose heart attack/conduction faults in the heart/arrhythmia/pacemaker malfunction. [1] (b) (i) Wave of conduction/excitation over the atria. [1] (ii) Wave of conduction/excitation over the ventricles. [1] (c) Patient attached to ECG; runs/walks briskly on treadmill; heart rate increased/BP increased; heart under strain; fault more likely to show in these circumstances. Any 4. [4] (a) Diagnosis of growths/tumours/soft tissue injuries. [1] (b) Less risk as X-rays can be harmful/cause mutations. Complete picture can be built up not just 2D. Provides detail of soft tissues. [1] [1] [1] (c) These/similar items would interfere with the magnetic field. [1] (d) It is impossible to keep the mouth completely still for any length of time. [1] GCE Applied Science SAMs (2009-2010)/ED 9 May 2008