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Dr.Osama Esmaeel Al-Mushhadany Wound Healing Body attempt to restore tissue to its structural and functional pre injury state. Wound healing either by regeneration or repair Wound Healing All tissues repair except? Liver and bone Wound Healing Normally Proceeds in an Organized Process Four Phases of Wound Healing 1-Hemostasis 2-Inflammation 3-Proliferation 4-Remodeling (maturation) Classification of wound closure and healing By primary intention 2. By secondary intention 3. By tertiary intention 1. Features of good scar 1234- Fine line scar Absence of contour irregularities No pigmentary irregularities No contracture or distortion Obtaining A Fine-Line Scar(good scar) The final appearance of a scar is dependent on many factors: (1) the age of the patient, type of skin and location on the body. (2) the tension on the closure. (3) the direction of the wound. (4) co-morbid conditions. (5) the technique used for skin closure. Obtaining A Fine-Line Scar .Age. Who will have better scar a child or elderly patient? Obtaining A Fine-Line Scar .Age. Loss of elasticity combined with changes in the subcutaneous tissue, produce wrinkling, which makes scars in older individuals less obvious and less prone to stretching. Child: raised red scar. Old age : flat white scar. Obtaining A Fine-Line Scar Type of skin: Type of skin should also be taken into account. Skin that is oily or pigmented, or both, produces more unsightly scars.. Obtaining A Fine-Line Scar Certain anatomic areas produce unfavorable scars that tend to become hypertrophic or widened. The shoulder and sternal area are notable examples. On the other hand, eyelid scars almost always heal with a fine-line scar Obtaining A Fine-Line Scar Nutritional status can affect wound healing. 1. 2. 3. 4. 5. Wounds gain strength less rapidly in the face of protein depletion. Vitamin A reverses the healing retardation caused by steroids. Vitamin C deficiency has long been known to cause scurvy, characterized by a failure of collagen synthesis. Zinc is required for epitheliazation and fibroblast proliferation. Ferrous iron and copper are necessary for normal collagen metabolism. Obtaining A Fine-Line Scar Co-morbid conditions such as anemia,ureamia and Diapedus can retard wound healing. . Obtaining A Fine-Line Scar Atraumatic technique by: Minimizing damage to the skin edges with atraumatic technique Debridement of necrotic or foreign material Good irrigation of traumatic or contaminated wounds. Careful handling of tissue. No crushing or dryness. No strangulation or tension. Hemostasis. Sharp knife. No hot sponges. Obtaining A Fine-Line Scar Skin lines The lines of tension in the skin were first noted byLanger(1861) who described the normal tension lines of the skin, called “Langer’s lines”. Or called “relaxed skin tension lines” Excision of lesions is planned when possible so that the final scar will be parallel to the relaxed skin tension lines. Maximal contraction occurs when a scar crosses the lines of minimal tension at a right angle. Wrinkle lines are generally the same as the relaxed skin tension lines. Method of homeostasis Electro-cautery. Ligature. Pressure and time. Clamping and twisting. Vasoconstrictor. Fibrin foam. Methods of suturing A. interrupted. B. Vertical mattress. C. Transvers mattress. D. Subcuticular . E. Continous. Factors determine the severity of suture markers 1.Time of removal of stitches . 2.Diameter of the suture . 3. Relation to wound edges. 4. Region of the body. 5.Absence of infection. 6. Propensity for keloid. When to remove the Stitches from different body sites? Sutures Are the most common materials used to close a wound. They are 2 types: 1. Absorbable: a. Natural : b. Catgut (plain , chromic) from submucosa of sheep intestine. Collagen suture from flexors of beeves. Synthetic: – – – Polyglycolic A.(Dexon ). Polyglactin 910 (Vicryl ). PDS (polydiaoxonon suture). Non-absorbable: 2. 1. 2. Natural : silk, cotton. stainless steel. Synthetic: 1. 2. 3. Polyamide (nylon): degrade 20 % / year. Polyester (Dacron, Ethibond) Polypropylene ( Prolene). Skin graft Definition: is a segment of epidermis and dermis that is removed without its blood supply from donor site transferred into a recipient site Types: according to: Origin: Autograft , allo-(homo), xeno(hetero)-, iso-graft (identical twins) Thickness: Split-thickness graft(Thiersch graft): thin ,intermediate, thick. Full thickness graft (Wolfe graft). Flaps “ part of tissue which retains its vascular attachment to body, transplanted to reconstruct a defect.” The flap donor site closed by suture or SSG. Skin tumors Basal cell carcinoma (BCC) Most common, 75% of skin tumors. Arise from basal layer of epidermis. Affects white skin, Male: Female=3:2 . Occurs on exposed parts: face, neck, scalp. No metastasis. Commonly Caucasian male older than 60 years Diagnosis: by biopsy (FNA, incisional biopsy , excisional biopsy) Treatment: Surgery: excision with 2-5 mm. healthy margin, & repair defect by skin graft or flap. Radiotherapy: in large lesion, oldman, refusing operation. Cryotherapy: for primary lesion < 2 cm., but hypopigmentation, scarring are disadvantages. Squamous Cell Carcinoma (SCC) is second most common skin cancer. arises from the malignant transformation of keratinocytes in the epidermis. arise either in normal skin or in preexisting lesion as (actinic keratosis, leukoplakia, radiation keratosis, scars( where called Marjolin ulcer). Clinically: present as irregular ulcer, everted edge, indurated base,attached deeply, blood-stained discharge,frequent lymph n. positive. Treatment: biopsy done. 1- Excision Surgical excision with 10-mm margin If lymph n. positive: excise lesion with lymph n. dissection. 2-Radiation therapy is best used in older patients, Alkhansah ospital Psc Cleft lip and palate One of the most frequently encountered congenital facial defects Embryology: result of breakdown in the normal lines of fusion during the early stage of fetal development Etiology of the clefts The cause of the cleft lip and palate is multifactorial involving both genetic and environmental factors 15% of the cleft cases are syndromatic with more than 170 syndrome have it as a feature Smoking is now well known to increase the incidence of clefting Multivitamine and folic acid in the 1st four months of pregnancy is protective Types of cleft lip and palate Types of cleft palate Common questions asked by the family 1-How to feed the baby 2-Timing of surgery 3-How many operation needed Feedings It is important to keep the cleft clean Breastfeeding is extremely challenging. Repair :lip at 3 months or rule of 10 (10 pounds weight, 10 gm Hb, 10 weeks old). Palate : at 12-18 months, by Veau-Wardil, 4 flaps, Langenbek. Aim of repair: lip: to improve appearance Palate: to achieve normal speech and prevent regurgitation . Millard op. Veau-Wardil op. Langenbek Effects on child : Inability to suck. Speech –nasal. Dentition deformity Nose deformity. Hearing defects.