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Chapter 6 : Chromosomes
and Cell Reproduction
Section 3: Mitosis & Cytokinesis
Chromatid Separation in Mitosis
• During mitosis the chromatids on each
chromosome are physically moved to opposite
sides of the dividing cell with the help of the
spindle.
• Spindles are cell structures made up of both
centrioles and individual microtubule fibers that are
involved in moving chromosomes during cell
division.
Forming the Spindle
• When a cell enters the
mitotic phase, the
centriole pairs start to
separate, moving
toward opposite poles
of the cell.
• As the centrioles
move apart, the
spindle begins to
form.
Separation of Chromatids by Attaching Spindle
Fibers
• The chromatids are moved to
each pole of the cell in a
manner similar to bringing a
fish in on a fishing rod and reel.
• When the microtubule “fishing
line” is “reeled in,” the
chromatids are pulled to
opposite poles.
• As soon as the chromatids
separate from each other they
are called chromosomes.
Mitosis
•Step 1: Prophase
• Chromosomes
condense and
become visible. The
nuclear envelope
dissolves and a
spindle forms.
Mitosis (continued)
• Step 2: Metaphase
• The chromosomes
move to the center of
the cell and line up
along the equator.
Spindle fibers link the
chromatids of each
chromosome to
opposite poles.
*longest phase of
mitosis!
Mitosis (continued)
• Step 3: Anaphase
• Centromeres divide, and
two chromatids (now
called chromosomes)
move toward opposite
poles as spindle fibers
attached to them begin to
shorten.
• “Ana” means “back” or
“backward”
Mitosis (continued)
• Step 4: Telophase
• A nuclear envelope forms
around the chromosomes
at each pole.
• Chromosomes, now at
opposite poles of the cell,
uncoil and the spindle
dissolves. Spindle fibers
break down and
disappear.
MITOSIS IS NOW
COMPLETE
Cytokinesis
• As mitosis ends, cytokinesis
begins.
• During cytokinesis, the
cytoplasm of the cell is divided
in half and the cell membrane
grows to enclose each cell,
forming two separate cells as a
result.
• The end result of mitosis and
cytokinesis is two genetically
identical cells, where only one
cell existed before.
Cytokinesis: Animal Cells vs. Plant Cells
Animal Cells
• Lack a cell wall
Plant Cells
• Vesicles formed by the golgi
apparatus fuse at the midline of
the dividing cell and form a cell
plate across the middle of a
plant cell.
• Cell is pinched in half by a belt • A new cell wall forms on both
of protein threads, forming two
sides of the plate and separates
separate animal cells.
into two plant cells.
MITOSIS
EXIT SLIP
• Draw each step of mitosis and describe what is happening during
each step!
• You can use your notes!
• Place in inbox before you leave.
• Make sure your NAME, PERIOD, AND DATE are at the top of your
paper. Thanks!