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Resources with Free Access For NHS Medicines Information Services This is a list of resources that are freely accessible and considered useful to NHS MI services. It includes free paper resources (e.g. BNF, drug tariff) and freely accessible websites via the Internet or via National library arrangements. This list is not intended to be exhaustive. It is organised under general subject headings and should be used in conjunction with ‘Resources for Purchase by NHS Medicines Information Services’. Other UKMi resources give guidance on what resources to use when, e.g. UKMi workbook, Enquiry Answering Guidelines. There is also guidance on the risks associated with the use of various resources available in Limitations of Common Information Sources used by UKMi at http://www.ukmi.nhs.uk/filestore/ukmiacg/LimitationsofCommonInformationSourcesv6-June2014_3.doc. Although UKMi cannot assure the quality of the listed resources, all those listed are produced by reputable/well known organisations. URLs are available for download via the MiDatabank administrators and were correct at the time of publication but are liable to change. Where registration is required this is indicated. This document may also be used to store details of your departmental usernames and passwords if you haven’t entered them in MiDatabank. This can then be kept in an accessible place for all staff working in MI. See also Effective use of the Internet for Enquiry Answering for guidance on how to assess the quality of a website. Updating the List This list will be updated with new editions/ URLs etc. on an ongoing basis. The Clinical Governance Working Group reviews the content of the list periodically although the content of the website or resource is not formally reviewed. Suggestions for additions or deletions can be forwarded to [email protected] . Changes since October 2014 Title Authors/ Publisher URL and general notes Paediatric Formulary 9th Edition 2014 Guy’s, St Thomas’ and Lewisham Hospitals Change: addition to the list Hard copy no longer available for purchase. A downloadable PDF is available for free. http://www.guysandstthomas.nhs.uk/resources/publications/for mulary/paediatric-formulary-9th-edition.pdf Medicines Compliance Aid (MCA) database UKMi Change: addition to the list http://www.ukmi.nhs.uk/applications/mca/ Memorial SloanKettering Cancer Centre Integrative Medicine Service Change: addition to the list http://www.mskcc.org/cancer-care/integrative-medicine/aboutherbs-botanicals-other-products Date: February 2015 Title Username/ password Authors/ Publisher URL and general notes General British National Formulary BMA and RPS (twice yearly) One paper copy considered essential for each MI centre (only the September edition is published for free; March edition only available fro purchase). Online access preferred as updated monthly www.medicinescomplete.com/mc/bnf/current/ DoH—Department of Health DoH https://www.gov.uk/government/organisations /department-of-health Drug Safety Update MHRA https://www.gov.uk/drug-safety-update Drug Tariff The Stationery Office (monthly) Only available online www.ppa.org.uk/ppa/edt_intro.htm electronic Medicines Compendium (eMC) DataPharm Communications http://www.medicines.org.uk/emc/ England: www.evidence.nhs.uk/nhs-evidencecontent/journals-and-databases. Athens password required. Wales: http://howis.wales.nhs.uk Scotland: www.knowledge.scot.nhs.uk/home.aspx EMBASE Google search engine Google www.google.co.uk for general seach engine but also use Google scholar for more academic focus http://scholar.google.co.uk/ Medicines Q & As UKMi http://www.ukmi.nhs.uk/activities/medicinesQ As/default.asp An excel spreadsheet is available (with links) to all current Q & As. Q & As can also be accessed via the NICE evidence search www.evidence.nhs.uk (filter by Type of information ‘Evidence Summaries’ and Source ‘UKMi') England: www.evidence.nhs.uk/nhs-evidencecontent/journals-and-databases Athens password required. Wales: http://howis.wales.nhs.uk Scotland: www.knowledge.scot.nhs.uk/home.aspx Medline MHRA—Medicines & Healthcare Regulatory Agency MHRA www.mhra.gov.uk MIMS Monthly Index of Medical Specialities Haymarket Medical Pubs. www.emims.net Username and password required. NB. Access free to MICs (contact Regional Centre for details) Netdoctor Collaboration of UK and European healthcare professionals www.netdoctor.co.uk www.netdoctor.co.uk/medicines/ For information about drugs, search the “Medicines” section rather than the whole site. Date: February 2015 Title Username/ password Authors/ Publisher URL and general notes General OTC Directory Proprietary Association of Great Britain Available in searchable form at www.medicinechestonline.co.uk. Use website drop down and selection criteria to access. UKMi UKMi www.ukmi.nhs.uk Some areas are password protected (contact Regional Centre for password) UKMi Discussion Group Ecompass (host) http://list.ecompass.nl/listserv/cgibin/wa?A0=MI-UK Adverse effects CHM—Commission on Human Medicines CHM/MHRA www.mhra.gov.uk/Committees/Medicinesadvi sorybodies/CommissiononHumanMedicines/i ndex.htm. Drug Analysis Prints (DAPs) for Yellow Card data MHRA http://www.mhra.gov.uk/drug-analysisprints/drug-analysis-prints-a-z/index.htm INCHEM International Programme on Chemical Safety www.inchem.org/. Toxicology information on chemicals and drugs. TOXNET US National Library Medicine http://toxnet.nlm.nih.gov/. Toxicology information including pregnancy related toxicity information. Also links to LactMed (see below) for drugs in lactation information. G6PD website Associazione Italiana Favismo http://www.g6pd.org/. Associazione Italiana Favismo is affiliated with UNIAMO, Italian Federation for Rare Diseases, which is member of EURORDIS, European Organization for Rare Diseases. This site should not be used in isolation for g6pd queries; no single resource is comprehensive. This site contains lists of safe and unsafe drugs and also attempts to quantify risk (low vs. high). Availability IDIS World Medicines IDIS World Medicines www.idispharma.com Durbin PLC Durbin PLC www.durbin.co.uk Pro-file Database Guy’s and St Thomas’ Hospital NHS Trust Sourcing unlicensed ‘special’ medicines. www.pro-file.nhs.uk. Registration required. Complementary Medicine Memorial SloanKettering Cancer Centre Date: February 2015 Integrative Medicine Service http://www.mskcc.org/cancer-care/integrativemedicine/about-herbs-botanicals-otherproducts Information for patients is also available Title Username/ password Authors/ Publisher URL and general notes Complementary Medicine Safety of Herbal Medicines MHRA www.mhra.gov.uk/Safetyinformation/Safetywa rningsalertsandrecalls/Safetywarningsandmes sagesformedicines/Safetywarningsandmessa gesforherbalmedicines/index.htm Contraception and Hormone Replacement Therapy IPPF Directory of Hormonal Contraceptives International Planned Parenthood Federation http://contraceptive.ippf.org Registration required. Can be used to identify foreign contraceptive pills. Family Planning Association Family Planning Association www.fpa.org.uk Contraception and Hormone Replacement Therapy Faculty of Family Planning and Reproductive Healthcare Royal College of Obstetricians and Gynaecologists www.ffprhc.org.uk/. Useful guidelines including choice of a contraceptive agent at different ages, in breast feeding, inflammatory bowel disease, interactions, missed pills and using pills outside their product licence, EHC and product reviews. Diagnostic tests Labtests online Collaboration of professional societies and supported by the Department of Health. www.labtestsonline.org.uk/. Patient orientated. Drug abuse Drug Misuse and Dependence— Guidelines on Clinical Management (The Orange Guide) National Treatment Agency www.nta.nhs.uk/uploads/clinical_guidelines_2 007.pdf DrugScope DrugScope www.drugscope.org.uk National Institute on Drug Abuse The National Institute on Drug Abuse (US) www.nida.nih.gov Talk to Frank DoH / Home Office www.talktoFrank.com Drug administration Intravenous Drug Administration Guides UKMi recommends all centres have access to good quality IV administration guidance. IMG—Injectable Medicines Guide (Medusa) Health of Wales Information Service http://medusa.wales.nhs.uk or www.injguide.nhs.uk. NB. Available free to contributing Trusts and all Trusts in Wales & N Ireland. Stabilis Compiled by hospital pharmacists in France http://www.stabilis.org/ Compatibility and stability data to supplement other resources. Date: February 2015 Title Username/ password Authors/ Publisher URL and general notes Drug interactions HIV Drug Interactions The University of Liverpool www.hiv-druginteractions.org Hepatitis drug interactions The University of Liverpool www.hep-druginteractions.org Cytochrome P450 website Indiana University http://medicine.iupui.edu/flockhart/ QT prolongation US education organisation AZCERT www.azcert.org. List drugs that prolong the QT Interval and/or induce Torsades de Pointes by risk category. Medscape drug interaction checker Medscape www.medscape.com/druginfo/drugintercheck er Registration required. Drugs.com interactions checker Cerner Multum http://www.drugs.com/drug_interactions.html To be used only after other approved sources have been used. Useful for information not readily available in UK sources. Evidence Based Medicine Evidence Search— Health and Social care NICE www.evidence.nhs.uk. General search engine for evidence based reviews relevant to the NHS. Bandolier Pain Research Group Oxford www.medicine.ox.ac.uk/bandolier N.B. It doesn’t look as if this site has been updated for some time. Still useful for explanations of terms e.g. NNT etc but do not use for evidence. The Cochrane Library The Cochrane Foundation John Wiley & Sons http://www.cochranelibrary.com/ Medicines and Prescribing Centre NICE http://www.nice.org.uk/mpc/index.jsp New site following integration of the former National Prescribing Centre into NICE. NICE -National Institute for Health and Care Excellence NICE www.nice.org.uk CKS Clinical Knowledge Summaries NICE http://cks.nice.org.uk/ SIGN—Scottish Intercollegiate Guidelines Network SIGN www.sign.ac.uk WeMeRec Bulletins Welsh Medicines Resource Centre www.wemerec.org HTA assessments National Coordinating Centre for HTA www.hta.ac.uk/ Many of these evaluations inform NICE guidance. Centre for Reviews and Dissemination University of York www.york.ac.uk/inst/crd/ Date: February 2015 Title Username/ password Authors/ Publisher URL and general notes Infections The Green Book Immunisation Against Infectious Disease DoH https://www.gov.uk/government/organisations /public-health-england/series/immunisationagainst-infectious-disease-the-green-book Immunisation Information Public Health England https://www.gov.uk/government/organisations /public-health-england/series/immunisation Public Health England Gov.uk https://www.gov.uk/government/organisations /public-health-england Replaces the Health Protection Agency site Lactation At least two resources should be used for all lactation enquiries. See also Resources for purchase list. LactMed US National Library of Medicine http://toxnet.nlm.nih.gov/cgibin/sis/htmlgen?LACT. UK Drugs in Lactation Advisory Service database Trent and West Midlands MIC UKMi http://www.midlandsmedicines.nhs.uk/content .asp?section=6&subsection=17&pageIdx=1 Legal and ethical Medicines, Ethics and Practice: A guide for pharmacists and pharmacy technicians RPS www.rpharms.com/law-and-ethics/medicinesethics-and-practice-guide.asp Only free to RPS members. New products NDO New Drugs Online UKMi www.ukmi.nhs.uk/applications/NDO/ Registration required (free). Also contains links to independent new medicines reviews. New medicines reviews UKMi/L(C)NDG UKMi/ L(C)NDG/ RDTC new medicines evaluations listed at http://www.ukmi.nhs.uk/activities/newProduct s/default.asp?pageRef=3 but available via www.evidence.nhs.uk NIHR Horizon Scanning Centre http://www.hsc.nihr.ac.uk/ Midlands Therapeutics and Review Advisory Committee (MTRAC) http://centreformedicinesoptimisation.co.uk/mt rac/committee-recommendations Click on relevant alphabetical files to access ‘Commissioning support sheets’ for listed products. Tick box and download to access pdf document. Patents Database UKMi http://www.midlandsmedicines.nhs.uk/content .asp?section=5&subsection=9&pageIdx=1 UKMi username and password required Prescribing Outlook UKMi http://www.ukmi.nhs.uk/activities/newProduct s/default.asp?pageRef=12 Scottish medicines Consortium (SMC) reviews SMC www.scottishmedicines.org.uk/ All Wales Medicines Strategy Group (AWMSG) reviews AWMSG www.wales.nhs.uk/sites3/home.cfm?OrgID=3 71 Date: February 2015 Title Username/ password Authors/ Publisher URL and general notes New products European Medicines Agency EMA www.ema.europa.eu Paediatrics BNF for Children 2014-2015 BMA, RPSGB, RCPCH & NPPG (annual) One paper copy considered essential for each MI centre (published annually)online via. Online access preferred since the content is updated monthly. http://www.medicinescomplete.com/mc/bnfc/c urrent/ Paediatric Formulary 9th Edition, 2014 Guy’s, St Thomas’ and Lewisham Hospitals 9th edition available as a PDF via: http://www.guysandstthomas.nhs.uk/resource s/publications/formulary/paediatric-formulary9th-edition.pdf. An iApp is due to be released in March 2015 (small charge will apply) Medicines for Children Partnership RCPCH, NPPG and WellChild. http://www.medicinesforchildren.org.uk/. Also contains patient information leaflets. Palliative care Palliative Adult Network Guidelines (PANG) Developed by a collaboration of UK Cancer networks Freely available at http://book.pallcare.info/. This should be used as a core resource in preference to the print version, but not the electronic version, of Palliative Care Formulary (see below). Palliative Care Matters Network of Palliative Care healthcare professionals. www.pallcare.info/ Use in preference to PANG for syringe driver compatibilities www.pallcare.info/mod.php?mod=sdrivers&m enu=14 Palliativedrugs.com (Palliative Care Formulary on-line) Robert Twycross & Andrew Wilcock www.palliativedrugs.com (Registration required), but the syringe driver tables are freely available using login (click on SDSD tab). Patient information NHS Choices Gov.uk http://www.nhs.uk Patient UK Patient Information Publications/ Egton Medical Information Systems www.patient.co.uk. This site has useful healthcare professional pages (see Therapeutics section below). Medicines Guides Datapharm Communications www.medicines.org.uk/Guides Pharmaceutical The Fridge Database Northwick Park MIC UKMi www.ukmi.nhs.uk/Secure/Fridge/Index.asp UKMi username and password required Medicines Compliance Aid (MCA) database Southwest Medicines Information UKMi http://www.ukmi.nhs.uk/applications/mca/ Date: February 2015 Title Username/ password Authors/ Publisher URL and general notes Pregnancy At least two resources should be used for all pregnancy enquiries. See also Resources for purchase list. TOXBASE UKTIS* UK Teratology Information Service www.toxbase.org Registration required. Monographs not suitable as patient information leaflets—see BUMPs. Royal College of Obstetrics and Gynaecology Royal College of Obstetrics and Gynaecology https://www.rcog.org.uk A range of guidelines on women’s health is available. BUMPS—Best use of medicines in pregnancy UKTIS www.medicinesinpregnancy.org. Produced by UKTIS. Provides information factsheets (containing essentially the same information as Toxbase) suitable for members of the public which can be used in discussion with a health care provider. Inclusion on this list does not endorse its use by patients without such support. Psychiatry www.switchwiki.eu Psychiatrienet http://wiki.psychiatrienet.nl/index.php/Main_P age Contains tables for: Switching between antidepressants Switching between antipsychotics Benzodiazepine conversion calculator NB. Inaccuracies in some tables have been identified. The authors have subsequently corrected these. This resource should only be used in conjunction with other resources and, ideally, be discussed with a mental health specialist Liver impairment LiverTox Date: February 2015 See opposite for details. http://livertox.nlm.nih.gov/index.html This resource is a joint venture between the Liver Disease Research Branch of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the Division of Specialized Information Services of the National Library of Medicine (NLM), National Institutes of Health Title Username/ password Authors/ Publisher URL and general notes Statistics Statistics in Divided Doses North West MIC UKMi www.ukmi.nhs.uk/activities/Research/default. asp?pageRef=27 Therapeutics Patient UK Patient Information Publications / Egton Medical Information Systems www.patient.co.uk. After putting a term in the search box you will have a list of resources to choose from. Those with an apple and a plus sign are written for healthcare professionals and are an excellent resource with the following general headings: presentation, diagnosis, aetiology, epidemiology, assessment, management etc. The Merck Manual of Diagnosis and Treatment Berkow, R et al Merck and Co. www.merckmanuals.com/professional/index.h tml. The latest edition can also be purchased as a hard copy. Dermnet New Zealand Dermatological Society www.dermnetnz.org/ A useful starting point for background information and advice for dermatological enquiries. Travel Malaria Reference Laboratory HPA (now part of Public Health England) www.malaria-reference.co.uk National Travel Health Network and Centre (NaTHNaC) National Travel Health Network and Centre, DoH www.nathnac.org. This advice is based on that produced by the HPA (now Public Health England) and may differ from advice in other sources (i.e. Travax, Fit for Travel). However, all advice is evidence based. It is advised that one resource only is used in these circumstances. Health Advice for Travellers NHS England http://www.nhs.uk/nhsengland/Healthcareabr oad/pages/Healthcareabroad.aspx Fit for Travel Provided by NHS Scotland. www.fitfortravel.nhs.uk. Public access site for sister site Travax. This advice is based on that produced by NHS Scotland and may differ from advice in other sources (i.e. NaTHNac). However, all advice is evidence based. It is advised that one resource only is used in these circumstances. Wound management and dressings Dressings.org Date: February 2015 Surgical Materials Testing Laboratory www.dressings.org NB website last modified Nov 2011