Download Amoxicillin 80 to 90 mg/kg/day

THE DOSE MAY
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CONSIDER &
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Example of a 90 mg/kg/day prescription for acute otitis media
Typical HIGH DOSE
Amoxicillin Prescription
If using 250 mg/5mL
Child’s WEIGHT
(kilograms)
Child’s WEIGHT
(approx. pounds)
Typical AGE for Child
of this Weight
7
15
6 to 11 months
300 mg BID =
6 mL BID
9
20
12 to 23 months
400 mg BID =
8 mL BID
14
30
2 to 3 year old
625 mg BID =
12.5 mL BID
18
40
4 to 5 year old
800 mg BID =
16 mL BID
23
50
6 to 7 year old
1000 mg BID =
20 mL BID
27
60
8 to 9 year old
1200 mg BID =
24 mL BID
Typical
DURATION of
Treatment
10 days
5 days
(may be up to 10 days
if recurrent infection,
treatment failure or
perforated ear drum)
Usual maximum dose is 3 g / day CPS’15 states up to 4g/day for pneumonia in children
• Guidelines recommend high-dose amoxicillin for greater effectiveness in
infections commonly caused by intermediate-resistant Streptococcus pneumoniae.
• High-dose amoxicillin is indicated for acute otitis media (BID x 5 to 10 days), and
sometimes other infections, such as pneumonia (TID x 7 to 10 days).
• After completing a weight-based dose check on a pediatric prescription,
the higher dose range may sometimes appear alarmingly ‘adult-like’, but is
reasonable, effective and well-tolerated.
For more information, visit www.RxFiles.ca
References:
1.Blondel-Hill E, Fryters S. Bugs & Drugs: an antimicrobial/infectious diseases reference. Edmonton (AB): Alberta Health Services; 2017. App Accessed May 2017.
2. Anti-infective Review Panel.Anti-infective Guidelines for Community Acquired Infections. Toronto: MUMS Guideline Clearinghouse; 2013. App Accessed 2017.
3. Sanford Guide Committee. The Sanford Guide to Antimicrobial Therapy, 47th Edition. Antimicrobial Therapy, INC; 2017.
4. Nicole Le Saux, Joan L Robinson; Canadian Paediatric Society (CPS) Infectious Diseases and Immunization Committee Paediatr Child Health 2016;21(1):39-44.
Accessed online 17 May 2017 at http://www.cps.ca/assets/pdfreactor/pdf.php?lang=en&paper=acute-otitis-media
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