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BCNH SFC Learning Outcomes (14-15) Science Foundation Course Learning Outcomes On successful completion of the course, students will be able to: Use ideas about chemical and biological building blocks and apply these concepts to explaining phenomena occurring within biological systems. Indicative Content across the 6 Weekends Weekend 1 Content CHEMISTRY Components of Matter Defining the three states of matter (solids liquids and gases) and identifying their unique properties. Understanding the physical changes that occur during transitions between states of matter Definition of homogenous and heterogenous mixtures as distinguished from compounds and description of techniques to separate mixtures Description of elements and compounds, atoms and molecules and their relationship to one another Features of atomic structure Sub-atomic particles- protons, neutrons and electrons Ions Isotopes Mass Number Atomic Number Relative Atomic Mass Electronic Configuration- arrangement of shells and subshells in terms of orbitals (s, p, d, f), filling of orbitals (Aufbau principle) and Pauli Exclusion Principle. Lewis Dot diagrams System International SI units of measurement Scientific Notation Order of Magnitude SI units Periodic table Understanding the patterns of arrangement of elements into groups and periods - Patterns of reactivity within groups - Valency within groups 1 © BCNH 2005-2014 BCNH SFC Learning Outcomes (14-15) - Electronic configuration and across periods Atom size within groups and periods Components of Matter Defining the three states of matter (solids liquids and gases) and identifying their unique properties. Understanding the physical changes that occur during transitions between states of matter Definition of homogenous and heterogenous mixtures as distinguished from compounds and description of techniques to separate mixtures Description of elements and compounds, atoms and molecules and their relationship to one another Features of atomic structure Sub-atomic particles- protons, neutrons and electrons Ions Isotopes Mass Number Atomic Number Relative Atomic Mass Electronic Configuration- arrangement of shells and subshells in terms of orbitals (s, p, d, f), filling of orbitals (Aufbau principle) and Pauli Exclusion Principle. Lewis Dot diagrams System International SI units of measurement Scientific Notation Order of Magnitude SI units Periodic table Understanding the patterns of arrangement of elements into groups and periods - Patterns of reactivity within groups - Valency within groups - Electronic configuration and across periods - Atom size within groups and periods Compound Formation Understanding and explaining the role of the outer shell electron in chemical bonding and intramolecular forces: - Features of Ionic Bonding- metal and non-metals; full transfer of electrons - Features of covalent bonding- two non-metals; sharing of electrons - Dative Bonding- electron pair contributed by one atom and shared by two Lewis Dot diagrams Weekend 2 Content CHEMISTRY Compound Formation 2 © BCNH 2005-2014 BCNH SFC Learning Outcomes (14-15) Understanding and explaining the role of the outer shell electron in chemical bonding and intramolecular forces: - Dative Bonding- electron pair contributed by one atom and shared by two Representing chemical reactions through writing word and balanced symbol equations Stoichiometry Describing the features of homolytic and heterolytic cleavage: - Nucleophiles - Electrophiles Redox Reactions- oxidation and reduction Intermolecular Forces Understanding how compound features are determined by intermolecular forces Describing the features of intermolecular forces - Dispersion forces - Hydrophobic forces - Permanent dipole interactions - Hydrogen bonds - Ionic interactions - Van der Waals forces Acids and Alkalis Definition of acids as proton donors and alkalis ad proton acceptors and hydroxide group releasers Testing for acids using Indicators Measuring acidity and alkalinity using pH Equilibrium and Le Chatelier’s principle Oxidation and Reduction Definition of oxidation as loss of electrons and reduction as gain of electrons (redox reactions) Explanation of the differences between an oxidising and reducing agents Biological examples of redox reactions Understanding oxidation numbers Weekend 3 Content CHEMISTRY Free Radicals Understanding that free radicals form as a result of homolytic cleavage Naming and writing the formulas of some free radicals Describing the key stages of free radical formation- Initiation, Propagation and Termination Explanation how antioxidants inhibit propagation Organic Chemistry and Functional Groups Description of the features of Alkanes, Alkenes and Alkynes Rules of Nomenclature of organic molecules 3 © BCNH 2005-2014 BCNH SFC Learning Outcomes (14-15) Alcohols, Ethers & Carbonyls Carboxylic Acids, Esters & Nitrogen-Based Groups Amides, Thiols & Aromatic Compounds Isomers- Structural and Stereoisomers Weekend 4 Content BIOLOGY & CHEMISTRY Amino Acids and Proteins Role of protein within the body Composition and generalised structure of amino acid Essential and Non-essential Amino acids Trans fatty acids and their implications for health Primary, Secondary, Tertiary and Quaternary structure of proteins Enzymes and Catalysts Role in lowering activation for increasing reaction rate Effect of temperature and pH on enzymatic function Enzyme Action: active site, substrate, co-enzymes, co-factors, inhibitors. Carbohydrates Composition of carbohydrates Classification of carbohydrates Monosaccharides, Disaccharides and Polysaccharides Aldoses, Ketose, Hexoses and Trioses Enantiomers Ring formation Presence of carbohydrates within biological systems Lipids Composition of lipids Classification of lipids Cis/Trans fats Essential fatty acids Simple/Complex lipids Weekend 5 Content BIOLOGY Cell Structure Structure of Animals and Plant cells Prokaryote vs eukaryote cells Organelles, cell wall, plasma membrane, nucleus, mitochondria, golgi apparatus, endoplasmic reticulum, ribosomes, lysosomes, chloroplasts, cilia Transport across plasma membrane Diffusion Osmosis Facilitated Diffusion Active 4 © BCNH 2005-2014 BCNH SFC Learning Outcomes (14-15) Endocytosis Exocytosis Structure of Nucleic acids Composition of nucleic acids- DNA, RNA, mRNA tRNA Role of nucleic acids DNA replication Human Genome Project Purpose of Mitosis/Meiosis and outline the stages within these Respiration Respiration equation C6H6O6 + 6O CO2 + H2O + 32ATP Stages within respiration; Glycolysis, Link Reaction, Kreb’s Cycle and Oxidative Phosphorylation Weekend 6 Content BIOLOGY & CHEMISTRY Acids/Alkalis The role of buffers in maintaining pH within a narrow range Chemistry of Supplements Definition Elemental Composition of vitamins and minerals Supplement examples and labelling Genetics Inheritance and Chromosomal abnormalities The Mammalian Transport System Structure and Function of Arteries, Veins and Capillaries The structure and function of blood Haemoglobin and transport of oxygen Obtaining Oxygen-gaseous exchange in the alveoli Weekend 7 Content Revision & Mock Exam 5 © BCNH 2005-2014