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MEDIA ALERT – CALLING FOR HEAD AND NECK CANCER PATIENTS TO TAKE PART IN A NEW STUDY FOR IMMEDIATE RELEASE: FRIDAY 13TH FEBRUARY 2015 To set up an interview and for more information please call Media Ambitions on + 44 (0) 208 940 2222 or email [email protected] “Head and neck cancers are usually treated with surgery, radiotherapy or chemotherapy or a combination of these treatments. Improvements in focussing chemotherapy treatment to the areas affected by the cancer will improve effectiveness and reduce side-effects of treatment. This study which is being carried out with Cancer Research UK will help to do just this.” Dr Vinod Joshi. Founder, the Mouth Cancer Foundation The Mouth Cancer Foundation, one of the UK’s leading mouth cancer charities, is keen to support a new study looking at a type of light treatment with chemotherapy for head and neck cancer patients as it may be a lifeline for those whose cancer returns. This study, which has been approved by the hospital’s independent ethics committee and the national regulatory authorities, is being carried out by PCI Biotech and supported by Cancer Research UK. It is looking at how well a combination of laser light treatment and a chemotherapy drug called bleomycin works to treat people with head and neck cancer. Researchers are looking at a new cancer treatment called PCA11. With this treatment patients have 2 drugs. The first is called Amphinex, which makes body tissue sensitive to light. The second is bleomycin chemotherapy. After you have had Amphinex and bleomycin, the doctor directs a laser light either onto the surface of the cancer, or through fibres that are put directly into the cancer. The light activates the Amphinex, which in turn helps the bleomycin to get into the cancer cells and kill them. Patients usually require several treatments of bleomycin. But researchers hope that the study will prove only one dose is required. The aim of this study is to see if this treatment works and if it will be a safe choice for people with head and neck cancer that has come back after previous treatment. For full details of the study and conditions of taking part please http://www.cancerresearchuk.org/about-cancer/trials/a-study-looking-type-light-treatment-withchemotherapy-cancer-head-neck -ENDS- visit For general press enquiries, please contact: Elizabeth Ayto Laverack or Izabela Nair Media Ambitions - +44 208 940 2222 [email protected] [email protected] www.mediaambitions.com NOTES TO EDITORS The Mouth Cancer Foundation – www.mouthcancerfoundation.org The Mouth Cancer Foundation is a registered charity no. 1109298. The Mouth Cancer Screening Accreditation Scheme aims to improve outcomes for head and neck cancers in accordance with The British Dental Association’s occasional paper for the early detection and prevention of oral cancer and NICE guidelines. It offers a realistic approach for dentists who seek to adopt best practice in oral cavity examination and opportunistic screening. The scheme embraces recent Care Quality Commission, Information Governance and Clinical Governance requirements and necessitates the recommendation by the General Dental Council for continuous professional development for the management of oral cancer for dentists. The Mouth Cancer Screening Accreditation Scheme is open to any dental practice whose clinicians are registered with the GDC. For more please contact the Mouth Cancer Foundation via [email protected] or call +44 (0) 1924 950 950 for more information. About Mouth Cancer Around 60,000 people in the UK will be diagnosed with mouth cancer over the next decade. In the UK, 7,700 people were diagnosed with Mouth Cancer in 2011. Tobacco use is still considered the main cause of mouth cancer. According to the World Health Organisation, up to half of current smokers will die of a tobacco-related illness – including mouth cancer. Drinking to excess can increase the risk of mouth cancer by four times. Those who smoke and drink are up to 30 times more likely to develop mouth cancer. Mouth cancer is twice more common in men than in women, though an increasing number of women are being diagnosed with the disease. Age is another factor, with people over the age of 40 more likely to be diagnosed, though more young people are now being affected than previously. Poor diet is linked to a third of all cancer cases. Experts suggest the Human Papilloma Virus (HPV), transmitted through oral sex, could overtake tobacco and alcohol as the main risk factor within the coming decade. Cancers can occur in any part of the mouth, tongue, lips, and adjacent areas like the throat, salivary glands, pharynx, larynx, sinus, and other sites in the head and neck area. Symptoms include: An ulcer or white or red patch anywhere in the mouth that does not heal within 3 weeks. A lump or swelling anywhere in the mouth, jaw or neck that persists for more than 3 weeks. A difficulty in swallowing, chewing or moving the jaw or tongue. A numbness of the tongue or other area of the mouth. A feeling that something is caught in the throat. A chronic sore throat or hoarseness that persists more than 6 weeks. An unexplained loosening of teeth with no dental cause. More information about Mouth Cancer is available at the Mouth Cancer Foundation web site www.mouthcancerfoundation.org or by emailing [email protected] PCI Biotech – www.pcibiotech.com PCI Biotech is a cancer focused biopharmaceutical company headquartered in Norway and listed on the Oslo Stock Exchange. The company is developing therapeutic products based on its proprietary photochemical internalisation (PCI) technology. The PCI technology induces triggered endosomal release and may be used to unlock the true therapeutic potential of a wide array of modalities, such as small molecules, ADCs and siRNA. Two programs are currently in clinical development in patient populations with a high unmet medical need; recurrent head & neck cancer (phase II) and bile duct cancer (phase I/II).