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Cellular Respiration

Cellular Respiration: metabolic reactions
that convert stored chemical energy into
usable chemical energy (ATP).

Where? inside cells of organisms

Two Major Types
 Aerobic Respiration- oxygen (electron
acceptor) is required to generate ATP
 Anaerobic Respiration- talk about this later.
Food is ingested
Food is modified- broken
down
Is Oxygen Present to
accept electrons?
Aerobic
Respiration
YES!
i. Kreb’s Cycle
ii. Electron Transport Chain
NO!
Anaerobic
Respiration
Fermentation
• Lactate
• Ethanol + CO2
Food is ingested
Food is modified- broken
down into monomers
Is Oxygen Present to
accept electrons?
Aerobic
Respiration
YES!
i. Kreb’s Cycle
ii. Electron Transport Chain
NO!
Anaerobic
Respiration
Fermentation
• Lactate
• Ethanol + CO2
Stage 1 of Cellular Respiration
Most Common Example: Glycolysis

Glycolysis: breaking
down of glucose

Glucose  pyruvate
+ ATP

Pyruvate = 3 Carbon
sugar
O2
Steps of Glycolysis
1.
Phosphates from two ATP molecules are transferred to
a single glucose molecule to make a 6- C- PP
compound (takes three reactions)
2.
The 6-C-PP compound is broken down into two 3- C- P
compounds (takes two reactions)
3.
Another phosphate is is added to the two 3- C- P
compounds to make two 3- C- PP compounds
4.
Each 3- C- PP compound is converted into pyruvate,
producing four 3-C pyruvates (takes four reactions)
Food is ingested
Food is modified- broken
down
Is Oxygen Present to
accept electrons?
Aerobic
Respiration
YES!
i. Kreb’s Cycle
ii. Electron Transport Chain
NO!
Anaerobic
Respiration
Fermentation
• Lactate
• Ethanol + CO2
Inner
Compartment
Inside of Cell
Aerobic Respiration
Summary

Goal: To make lots of ATP = usable chemical
energy for the cell
Krebs Cycle

Uses pyruvate to free electrons

Electron Carriers: NADH, FADH2
Electron Transport Chain

Electrons used to create a H+ gradient to leave via
ATP synthase to make ATP.
Pre- Krebs Cycle

Pyruvate enters a mitochondrion and is
converted into a 2-C compound

By product is a 2-C acetyl molecule (different 2C compound)

Acetyl binds to a molecule called coenzyme A
(CoA) to make acetyl-CoA.
Krebs Cycle
1.
Acetyl-CoA binds to a 4-C compound, to make a 6-C
compound and releases coenzyme A
2.
CO2 is released from 6-C compound, to make a 5-C
compound. Electrons are transferred to NAD+, to make
NADH
3.
CO2 is released from the 5-C compound, to make a 4-C
compound. ATP is made and NADH are made
4.
4-C compound is converted into a different 4-C
compound. Electrons are transferred to FAD, to make
FADH2
5.
New 4-C compound is converted to original 4-C
compound to continue cycle. NADH is made.
Electron Transport Chain
1.
Electrons from electron carriers NADH and FADH2
pass through the ETC located in the inner
mitochondria membrane
2.
Energy from the electrons is used to pump H+ ions
outside the inner mitochondria compartment
3.
Since there is a higher concentration of H+ ions
outside, they are transported back inside through
carrier protein ATP Synthase
4.
ATP Synthase uses the H+ ion gradient to combine
ADP & P to make ATP
5.
The used electrons and H+ ions bind with oxygen to
form water.
Aerobic Respiration Movie
Topic- Glycolysis, Krebs
Cycle, ETC
Tools- camera, large dry
erase board and dry
erase markers.
Rubric- max 5 pts each
Accuracy

Vincent and Gavin

Gaby and Kira

Luke and Alivia

Claire and Grant

Alvaro and Thomas

Andrew and Maddie

Shruti and Dominic
Easy to See/ Hear
Intriguing/ Creative