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HIV genome map
This genetic map of the HIV-1 viral genome depicts the
structural and regulatory genes in their relative position as
well as their products and functions.
- The remaining genes (vif, vpr, vpu, rev and nef) are regulatory
genes whose products play critical roles in controlling viral expression of
viral gene products within the infected cell.
-The rev-responsive element (RRE) is the binding site for the rev gene
product which transport RNA massage from the nucleus
HIV-1 and related Retroviruses
Primate lentiviruses
Studies of the
African green monkey
and their related
simian
virus (SIVagm)yield
important information
in our understanding
of
HIV-1 and HIV-2.
There are three major species of
African green monkeys
This map of Africa
indicates the native
locations of different
species of the African
green monkey.Within
each species, a unique
family of SIVagm
has been show to
exist.
Geographic domain of African green monkeys
When the SIVagm
from different species
of African green
monkeys are genetically
mapped the phylogenic
tree demonstrates
unique clustering of
SIVagm based on the
species was obtained.
Phylogenic differences of SIVagm
SIVagm has
several subspecies
bas on the species
of African green
monkey
Subgroups of SIV