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Chapter Eleven Living with Cancer and Chronic Conditions Status of Cancer Today Annually, over 1.2 million people developed cancer [U.S. 2002] Contributing factors could be: • • • • • • aging tobacco use high fat foods pollution no health insurance lack of education Cell Regulation Cells perform important daily functions Regulatory genes – responsible for monitoring cell replication, specialization, DNA repair, and suppression Oncogenes – faulty regulatory genes that fail to function properly Proto oncogenes –normal regulatory genes that may become oncogenes Oncogene Formation All cells have proto oncogenes 3 mechanisms that contribute to oncogene formation: 1. genetic mutations 2. viral infections 3. presence of carcinogens, environmental agents Characteristics of a Cancerous Cell Infinite life expectancy (telomerase enzyme) Absence of contact inhibition Absence of cellular cohesiveness (metastasis) Ability to control extra blood supply (angiogenesis potential) Types of Cancers 1. 2. 3. 4. Carcinoma Sarcoma Lymphoma Leukemia Benign vs. malignant growths are not always safe Types of Cancers, cont. 1. 2. 3. 4. melanoma neuroblastom a adenocarcino ma hepatoma Benign vs. malignant growths are not always safe How Cancer Spreads Common Cancer Sites of the Body Lung Breast Uterus Vagina Ovary Lymph Cervix Prostate Testicle Colon/rectum Pancreas Skin Self-Check (Breast) Self-Check (Testicles) ABCDE’s of Skin Cancer Asymmetry Border Color Diameter Elevation 7 Warning Signs of Cancer Change in bowel/bladder habits A sore that won’t heal Unusual bleeding Thickening or lump Indigestion Obvious change in wart/mole Nagging cough Treatment for Cancer Surgery Radiation Chemotherapy Immunotherapy Alternative cancer therapies Risk Reduction Know family history Select occupation carefully Avoid tobacco Eat properly Monitor environmental exposure to carcinogens Risk Reduction (cont’d) Control body weight Exercise regularly Limit UV rays Consume alcohol moderately Other Chronic Health Conditions Systemic lupus erythematosus Crohn’s Disease Multiple Sclerosis Diabetes mellitus (Type 1 and 2) Alzheimer’s Disease Sickle Cell Disease Chapter Eleven Living with Cancer and Chronic Conditions