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Transparencies to accompany Hole’s Human Anatomy and Physiology, 11th edition 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. The structure of body parts make possible their functions Figure 1.2 The human body is composed of parts within parts Figure 1.3 Our cells lie within an internal environment, which they maintain Figure 1.5 A homeostatic mechanism monitors an aspect of the internal environment Figure 1.6 A thermostat is an example of a homeostatic mechanism Figure 1.7 The homeostatic mechanism that regulates body temperature Figure 1.8 Major body cavities Figure 1.9a Major body cavities Figure 1.9b The cavities within the head Figure 1.10 A transverse section through the thorax Figure 1.11 Transverse section through the abdomen Figure 1.12 The integumentary system covers the body Figure 1.13 The skeletal and muscular organ systems provide support and movement Figure 1.14 The nervous and endocrine organ systems Figure 1.15 The cardiovascular and lymphatic organ systems transport fluids Figure 1.16 The digestive, respiratory, and urinary organ systems Figure 1.17 The reproductive systems manufacture and transport sex cells Figure 1.18 The organ systems in humans interact to maintain homeostasis Figure 1.19 Sectioning the body along various planes Figure 1.20 A human brain sectioned along the sagittal plane Figure 1.21a A human brain sectioned along the transverse plane Figure 1.21b A human brain sectioned along the coronal plane Figure 1.21c Cylindrical parts cut in cross section, oblique section, or longitudinal section Figure 1.22 The abdominal area subdivided into nine regions Figure 1.23a The abdominal area subdivided into four quadrants Figure 1.23b Some terms used to describe body regions Figure 1.24 Human female torso showing the anterior surface and the superficial muscles Plate 1 28. Human male torso with the deeper muscle layers exposed Plate 2 29. Male torso with deep muscles removed and the abdominal viscera exposed Plate 3 30. Human male torso with the thoracic and abdominal viscera exposed Plate 4 31. Female torso with lungs, heart, and small intestine sectioned Plate 5 32. Female torso with heart, stomach, liver, and parts of the intestine and lungs removed Plate 6 33. Human female torso with the thoracic, abdominal, and pelvic viscera removed Plate 7 34. Saggital section of the head and trunk Plate 8 35. Saggital section of the head and neck Plate 9 36. Viscera of the thoracic cavity, sagittal section Plate 10 37. Viscera of the abdominal cavity, sagittal section Plage 11 38. Viscera of the pelvic cavity, sagittal section Plate 12 39. Transverse section of the head above the eyes, superior view Plate 13 40. Transverse section of the head at the level of the eyes, superior view Plate 14 41. Transverse section of the neck, inferior view Plate 15 42. Transverse section of the thorax through the base of the heart, superior view Plate 16 43. Transverse section of the thorax through the heart, superior view Plate 17 44. Transverse section of the abdomen through the kidneys, superior view Plate 18 45. Transverse section of the abdomen through the pancreas, superior view Plate 19 46. Transverse section of the male pelvic cavity, superior view Plate 20 47. Thoracic viscera, anterior view Plate 21 48. Thorax with the lungs removed, anterior view Plate 22 49. Thorax with the heart and lungs removed, anterior view Plate 23 50. Abdominal viscera, anterior view Plate 24 51. Abdominal viscera with the greater omentum removed, anterior view Plate 25 52. An atom of lithium Figure 2.1 53. A scan and illustration of the thyroid gland Figure 2B 54. Hydrogen molecules can combine with oxygen molecules to form water molecules Figure 2.2 55. Electron locations in hydrogen, helium, and lithium Figure 2.3 56. Formation of an ionic bond Figure 2.4 1 57. A hydrogen molecule forms when two hydrogen atoms share a pair of electrons and join by a covalent bond Figure 2.5 58. Structural and molecular formulas for molecules of hydrogen, oxygen, water, and carbon dioxide Figure 2.6 59. A water molecule can be represented by a threedimensional model Figure 2.7 60. Water is a polar molecule Figure 2.8 61. The polar nature of water molecules Figure 2.9 62. The pH values of some common substances Figure 2.10 63. Structural formulas for glucose--straight chain Figure 2.11a 64. Structural formulas for glucose--ring structure Figure 2.11b 65. The shape symbolizing the ring structure of a glucose molecule Figure 2.11c 66. A monosaccharide molecule consists of one 6carbon atom building block Figure 2.12a 67. A disaccharide molecule consists of two 6-carbon atom building blocks Figure 2.12b 68. A polysaccharide molecule consists of many building blocks Figure 2.12c 69. A molecule of saturated fatty acid Figure 2.13a 70. A molecule of unsaturated fatty acid Figure 2.13b 71. A triglyceride molecule Figure 2.14 72. A fat molecule contains a glycerol and three fatty acids Figure 2.15a 73. A phospholipid molecule Figure 2.15b 74. Schematic representation of a phospholipid Figure 2.15c 75. General structure of a steroid Figure 2.16a 76. The structural formula for cholesterol Figure 2.16b 77. General structure of an amino acid Figure 2.17a 78. Some representative amino acids and their structural formulas Figure 2.17b 79. A peptide bond between two amino acids Figure 2.18 80. The levels of protein structure Figure 2.19 81. A nucleotide Figure 2.20 82. A schematic representation of nucleic acid structure--RNA Figure 2.21a 83. A schematic representation of nucleic acid structure--DNA Figure 2.21b 84. The molecules of ribose and deoxyribose differ by a single oxygen atom Figure 2.22 85. Three-dimensional model of a water molecule Figure 2.23a 86. Three-dimensional model of a carbon dioxide molecule Figure 2.23b 87. Three-dimensional model of a glycine molecule Figure 2.23c 88. Three-dimensional model of a glucose molecule Figure 2.23d 89. Three-dimensional model of a fatty acid molecule Figure 2.23e 90. Three-dimensional model of a collagen molecule Figure 2.23f 91. Cells vary considerably in size Figure 3.1 92. Cells vary in shape and function Figure 3.2 93. A composite cell Figure 3.3 94. Human red blood cells viewed using a light microscope Figure 3.5a 95. Human red blood cells viewed using a transmission electron microscope Figure 3.5b 96. Human red blood cells viewed using a scanning electron microscope Figure 3.5c 97. The cell membrane is a phospholipid bilayer Figure 3.6 98. The cell membrane is composed primarily of phospholipids Figure 3.7 99. Some cells are joined by intercellular junctions Figure 3.8 100. Cellular adhesion molecules (CAMs) direct white blood cells to injury sites Figure 3.9 101. Rough ER is dotted with ribosomes, whereas smooth ER lacks ribosomes Figure 3.10b,c 102. The Golgi apparatus Figure 3.11b 103. Milk secretion Figure 3.12 104. A mitochondrion Figure 3.13 105. Centrioles Figure 3.15 106. Cilia are sweeping hairlike extensions Figure 3.16a 107. Cilia have a power stroke and a recovery stroke Figure 3.16b 108. Flagella form the tails of these human sperm cells Figure 3.17 109. The pores in the nuclear envelope Figure 3.20a 110. Transmission electron micrograph of a cell nucleus Figure 3.20b 111. An example of diffusion Figure 3.21 112. Diffusion Figure 3.22 113. Oxygen enters cells and carbon dioxide leaves cells by diffusion Figure 3.23 114. Facilitated diffusion Figure 3.24 115. Osmosis Figure 3.25 116. Placing red blood cells in an isotonic, hypertonic, or hypotonic solution Figure 3.26 117. Filtration of water and solids Figure 3.27 118. Filtration in the body Figure 3.28 119. Active transport Figure 3.29 120. A cell may take in a tiny droplet of fluid from its surroundings by pinocytosis Figure 3.30 121. A cell may take in a solid particle from its surroundings by phagocytosis Figure 3.31 122. A lysosome combines with a vesicle that contains a phagocytized particle Figure 3.32 123. Receptor-mediated endocytosis Figure 3.33 124. Exocytosis releases particless from cells Figure 3.34 2 125. Transcytosis transports HIV across the lining of the anus or vagina Figure 3.35 126. The cell cycle is divided into interphase and cell division Figure 3.36 127. Mitosis and cytokinesis Figure 3.37 128. A cancer cell is rounder and less specialized than surrounding healthy cells Figure 3.39 129. Steps in the development of cancer Figure 3.40 130. Stem cells and progenitor cells Figure 3.41 131. Cell lineages Figure 3.42 132. Two monosaccharides may join by dehydration synthesis to form a disaccharide Figure 4.1 133. A glycerol molecule and three fatty acid molecules may join by dehydration synthesis to form a fat molecule Figure 4.2 134. Two amino acid molecules unite by dehydration synthesis to form a peptide bond Figure 4.3 135. An enzyme catalyzed reaction Figure 4.4 136. A metabolic pathway Figure 4.5 137. A negative feedback mechanism Figure 4.6 138. An ATP molecule consists of an adenine, a ribose, and three phosphates Figure 4.7 139. ATP provides energy for cellular reactions; cellular respiration generates ATP Figure 4.8 140. Glycolysis Figure 4.9 141. Glycolysis breaks down glucose in three stages Figure 4.10 142. The citric acid cycle Figure 4.11 143. A summary of ATP synthesis by oxidative phosphorylation Figure 4.12 144. An overview of aerobic respiration Figure 4.13 145. Hydrolysis breaks down carbohydrates from foods into monosaccharides Figure 4.14 146. A summary of the breakdown (catabolism) of proteins, carbohydrates, and fats Figure 4.15 147. Each nucleotide of a nucleic acid consists of a 5carbon sugar; a phosphate group; and an organic, nitrogenous base Figure 4.16 148. A polynucleotide chain consists of nucleotides connected by a sugar-phosphate backbone Figure 4.17 149. DNA consists of two polynucleotide chains Figure 4.18 150. DNA and chromosome structure Figure 4.19 151. DNA molecule replicates Figure 4.20 152. RNA is single-stranded, contains ribose, and has uracil Figure 4.21 153. Synthesis of an RNA molecule Figure 4.22 154. DNA information is transcribed into mRNA, and mRNA is translated into a sequence of amino acids Figure 4.23 155. Protein synthesis occurs on ribosomes Figure 4.24 156. Mutation Figure 4.25 157. Four inborn errors of metabolism Figure 4.26 158. Simple squamous epithelium consists of a layer of tightly packed, flattened cells Figure 5.1a,b 159. Simple squamous epithelium Figure 5.1c,d 160. Simple cuboidal epithelium Figure 5.2 161. Simple columnar epithelium Figure 5.3 162. Pseudostratified columnar epithelium Figure 5.5 163. Stratified squamous epithelium Figure 5.6 164. Stratified cuboidal epithelium Figure 5.7 165. Stratified columnar epithelium Figure 5.8 166. Transitional epithelium Figure 5.9a,b 167. Transitional epithelium Figure 5.9c,d 168. Structural types of exocrine glands Figure 5.10 169. Glandular secretions Figure 5.11 170. Macrophages are scavenger cells common in connective tissues Figure 5.14 171. Scanning electron micrograph of a mast cell Figure 5.15 172. Abnormal collagen causes the stretchy skin of Ehlers-Danlos syndrome type I Figure 5.17 173. Loose connective tissue, or areolar tissue, contains numerous fibroblasts Figure 5.18 174. Adipose tissue cells contain large fat droplets that push the nuclei close to the cell membranes Figure 5.19 175. Reticular connective tissue is a network of thin collagenous fibers Figure 5.20 176. Regular dense connective tissue consists largely of tightly packed collagenous fibers Figure 5.21 177. Elastic connective tissue contains many elastic fibers between them Figure 5.22 178. Hyaline cartilage cells (chrondrocytes) are located in the lacunae Figure 5.23 179. Elastic cartilage contains many elastic fibers in its intercellular material Figure 5.24 180. Fibrocartilage contains many large collagenous fibers in its intercellular material Figure 5.25 181. Bone tissue Figure 5.26a,b 182. Blood tissue consists of red and white blood cells and platelets suspended in an intercellular fluid Figure 5.27 183. Skeletal muscle tissue is composed of striated muscle fibers with many nuclei Figure 5.28 184. Smooth muscle tissue consists of spindle-shaped cells, each with a large nucleus Figure 5.29 185. Cardiac muscle cells are branched and interconnected, with a single nucleus each Figure 5.30 186. A neuron with cellular processes extending into its surroundings Figure 5.31 187. An organ, such as the skin, is composed of several kinds of tissues Figure 6.1 188. A section of skin Figure 6.2a 189. Epidermis Figure 6.3 190. A melanocyte may have pigment-containing extensions that pass between epidermal cells and transfer pigment into them Figure 6.4b 3 191. A hair grows from the base of a hair follicle Figure 6.5 192. Scanning electron micrograph of a hair emerging from the epidermis Figure 6.6 193. Nails grow from epithelial cells Figure 6.7 194. A sebaceous gland secretes sebum into a hair follicle Figure 6.8 195. Location of the ducts of the eccrine and apocrine sweat glands Figure 6.9 196. Body temperature regulation is an example of homeostasis Figure 6.11 197. Healing of a wound Figure 6.13 198. Subdivision of the body into regions as an aid for estimating the extent of damage burns cause Figure 6.14 199. Bones are classified by shape Figure 7.1 200. Major parts of a long bone Figure 7.2 201. Photo of femur, epiphyses of the femur, and a skull bone Figure 7.3a 202. Compact bone is composed of osteons cemented together by bone matrix Figure 7.4 203. Fetal skeleton (fourteen-week old fetus) Figure 7.6a 204. Major stages in the development of an endochondral bone Figure 7.8 205. Epiphyseal plate Figure 7.9 206. Radiograph showing the presence of epiphyseal plates in a child's bones Figure 7.11 207. Increased amount of bone at the sites of muscle attachment Figure 7.12 208. Hormonal regulation of bone calcium resorption and deposition Figure 7.13 209. Sutural bones Figure 7.14 210. Major bones of the skeleton Figure 7.15 211. The hyoid bone Figure 7.16 212. Anterior view of the skull Figure 7.17 213. The orbit of the eye includes both cranial and facial bones Figure 7.18 214. Right lateral view of the skull Figure 7.19 215. Inferior view of the skull Figure 7.20 216. The sphenoid bone Figure 7.21 217. The ethmoid bone Figure 7.22 218. Lateral wall of the nasal cavity Figure 7.23 219. Floor of the cranial cavity Figure 7.24 220. Locations of the sinuses Figure 7.25 221. The palatine bones Figure 7.26 222. Sagittal section of the skull Figure 7.27 223. Coronal section of the skull Figure 7.28 224. Mandible Figure 7.29 225. Right lateral view of the infantile skull Figure 7.31a 226. Superior view of the infantile skull Figure 7.31b 227. The curved vertebral column Figure 7.32 228. Typical thoracic vertebra Figure 7.33 229. Superior view of the atlas and right lateral view and superior view of the axis Figure 7.34 230. Radiograph of the cervical vertebrae Figure 7.35 231. Superior view of a cervical vertebra Figure 7.36a 232. Superior view of a thoracic vertebra Figure 7.36b 233. Superior view of a lumbar vertebra Figure 7.36c 234. Sacrum and coccyx Figure 7.37 235. The thoracic cage Figure 7.38a 236. Radiograph of the thoracic cage Figure 7.38b 237. A typical rib Figure 7.39 238. The pectoral girdle Figure 7.40a 239. Scapula Figure 7.41 240. Right upper limb Figure 7.42a-c 241. Radiograph of the right elbow and forearm Figure 7.42d 242. Humerus Figure 7.43 243. Radius and ulna Figure 7.44 244. Wrist and hand Figure 7.45a-b 245. Radiograph of the right hand Figure 7.45c 246. A person with polydactyly has extra digits Figure 7.46 247. Pelvic girdle Figure 7.47a-b 248. Radiograph of the pelvic girdle Figure 7.47c 249. Coxa Figure 7.48 250. The female pelvis Figure 7.49 251. Radiograph of the right knee Figure 7.50a 252. Parts of the lower limb Figure 7.50b-d 253. Femur Figure 7.51 254. Bones of the right leg Figure 7.52 255. Radiograph view of the right foot from the medial side Figure 7.53a 256. The talus moves freely where it articulates with the tibia and fibula Figure 7.53b 257. Right foot viewed superiorly Figure 7.54a 258. Radiograph of the right foot viewed superiorly Figure 7.54b 259. The bones change to different degrees and at different rates over a lifetime Figure 7.55 260. The skull, frontal view Plate 26 261. The skull, left anterolateral view Plate 27 262. The skull, left posterolateral view Plate 28 263. Bones of the left orbital region Plate 29 264. Bones of the anterior nasal region Plate 30 265. Bones of the left zygomatic region Plate 31 266. Bones of the left temporal region Plate 32 267. The skull, inferior view Plate 33 268. Base of the skull, sphenoid region Plate 34 269. Base of the skull, occipital region Plate 35 270. Base of the skull, maxillary region Plate 36 271. Mandible, lateral view Plate 37 272. Mandible, medial surface of right ramus Plate 38 273. Frontal bone, anterior view Plate 39 274. Occipital bone, inferior view Plate 40 275. Temporal bone, left lateral view Plate 41 276. Ethmoid bone, right lateral view Plate 42 277. Sphenoid bone, anterior view Plate 43 278. Sphenoid bone, superior view Plate 44 279. The skull, sagittal section Plate 45 4 280. Ethmoidal region, sagittal section Plate 46 281. Sphenoidal region, sagittal section Plate 47 282. The skull, floor of the cranial cavity Plate 48 283. Frontal region, transverse section Plate 49 284. Sphenoidal region, floor of the cranial cavity Plate 50 285. Skull of a fetus, left anterolateral view Plate 51 286. Skull of a fetus, left superior view Plate 52 287. Skull of a child, right lateral view Plate 53 288. Skull of an aged person, left lateral view Plate 54 289. The articulation between the tibia and fibula Figure 8.1 290. Fibrous joints Figure 8.2 291. The articulation between the root of a tooth and the jawbone is a gomphosis Figure 8.4 292. The articulation between the first rib and the manubrium is a synchondrosis Figure 8.5 293. Fibrocartilage composes the symphysis pubis Figure 8.6 294. The generalized structure of a synovial joint Figure 8.7 295. Menisci separate the articulating surfaces of the femur and tibia Figure 8.8 296. Types and examples of synovial (freely movable) joints Figure 8.9a-c 297. Types and examples of synovial (freely movable) joints Figure 8.9d-f 298. Adduction, abduction, dorsiflexion, plantar flexion, hyperextension, extension, and flexion Figure 8.10 299. Rotation, circumduction, pronation, and supination Figure 8.11 300. Eversion, inversion, retraction, protraction, elevation, and depression Figure 8.12 301. The shoulder joint allows movement in all directions Figure 8.13a 302. Photograph of the shoulder joint Figure 8.13b 303. Ligaments associated with the shoulder joint Figure 8.14 304. The elbow joint Figure 8.15 305. Ligaments associated with the elbow joint Figure 8.16 306. The hip joint Figure 8.18a 307. Photograph of the hip joint Figure 8.18b 308. The major ligaments of the right hip joint Figure 8.19 309. The knee joint is the most complex of the synovial joints Figure 8.20a 310. Photograph of the knee joint Figure 8.20b 311. Ligaments within the knee joint help to strengthen it Figure 8.21 312. Nuclear scan of good and bad knees Figure 8.23 313. Tendons attach muscles to bones; aponeuroses attach muscles to other muscles Figure 9.1 314. A skeletal muscle is composed of a variety of tissues Figure 9.2 315. Skeletal muscle fiber Figure 9.4 316. A sarcomere Figure 9.5 317. Thick filaments are composed of the protein myosin, and thin filaments are composed of the protein actin Figure 9.6 318. A network of sarcoplasmic reticulum and a system of transverse tubules Figure 9.7 319. Neuromuscular junction Figure 9.8a 320. Muscle fibers within a motor unit may be distributed throughout the muscle Figure 9.9 321. Sliding filament theory Figure 9.10 322. When a skeletal muscle contracts, individual sarcomeres shorten Figure 9.11a 323. A muscle cell uses energy released in cellular respiration to synthesize ATP Figure 9.12 324. Oxygen required to support aerobic reactions of cellular respiration is carried in the blood and stored in myoglobin Figure 9.13 325. Liver cells can convert lactic acid, generated by muscles anaerobically, to glucose Figure 9.14 326. A myogram of a single muscle twitch Figure 9.15 327. The length-tension relationship of skeletal muscle Figure 9.16 328. Myograms of a series of twitches, summation, and a tetanic contraction Figure 9.17 329. Types of muscle contractions Figure 9.18 330. Transmission electron micrograph of intercalated discs of cardiac muscle Figure 9.19 331. Three types of levers Figure 9.20 332. Levers and movement Figure 9.21 333. The biceps brachii has two heads that originate on the scapula Figure 9.22 334. Anterior view of superficial skeletal muscles Figure 9.23 335. Posterior view of superficial skeletal muscles Figure 9.24 336. Muscles of facial expression and mastication Figure 9.25 337. Deep muscles of the back and the neck Figure 9.26 338. Muscles of the posterior shoulder Figure 9.27 339. Muscles of the anterior chest and abdominal wall Figure 9.28 340. Muscles of the posterior surface of the scapula and arm Figure 9.29 341. Cross section of the arm Figure 9.30 342. Muscles of the anterior shoulder and the arm, with the rib cage removed Figure 9.31 343. Muscles of the anterior forearm Figure 9.32 344. Muscles of the arm and forearm Figure 9.33 345. A cross section of the forearm (superior view) Figure 9.34 346. Isolated muscles of the abdominal wall Figure 9.35 347. Muscles of the male and female pelvic outlet Figure 9.36 5 348. Muscles of the anterior right thigh and isolated view of the vastus intermedius Figure 9.37 349. Muscles of the lateral right thigh Figure 9.38 350. Muscles of the thigh and leg Figure 9.39 351. A cross section of the thigh Figure 9.40 352. Muscles of the anterior right leg Figure 9.41 353. Muscles of the lateral right leg Figure 9.42 354. Muscles of the posterior right leg Figure 9.43 355. A cross section of the leg Figure 9.44 356. Surface anatomy of head and neck Plate 55 357. Surface anatomy of upper limb and thorax Plate 56 358. Surface anatomy of back and upper limbs Plate 57 359. Surface anatomy of torso and arms Plate 58 360. Surface anatomy of torso and thighs Plate 59 361. Surface anatomy of forearm Plate 60 362. Surface anatomy of the hand Plate 61 363. Surface anatomy of knee and surrounding area Plate 62 364. Surface anatomy of knee and surrounding area Plate 63 365. Surface anatomy of ankle and leg Plate 64 366. Surface anatomy of ankle and foot Plate 65 367. Lateral view of the head Plate 66 368. Anterior view of the trunk Plate 67 369. Posterior view of the trunk, with deep thoracic muscles exposed on the left Plate 68 370. Posterior view of the right thorax and arm Plate 69 371. Posterior view of the right forearm and hand Plate 70 372. Anterior view of the right thigh Plate 71 373. Posterior view of the right thigh Plate 72 374. Anterior view of the right leg Plate 73 375. Lateral view of the right leg Plate 74 376. Posterior view of the right leg Plate 75 377. Neurons are the structural and functional units of the nervous system Figure 10.1 378. Nervous system Figure 10.2 379. A common neuron Figure 10.3 380. The myelin sheath of a myelinated axon Figure 10.4a 381. Light micrograph of a myelinated axon Figure 10.4b 382. An axon lying in a longitudinal groove of a Schwann cell lacks a myelin sheath Figure 10.4c 383. A falsely colored transmission electron micrograph of myelinated and unmyelinated axons in cross section Figure 10.5 384. The multipolar neuron, the bipolar neuron, and the unipolar neuron Figure 10.6 385. Sensory neurons, interneurons, and motor neurons Figure 10.7 386. The microglial cell, oligodendrocyte, astrocyte, and ependymal cell Figure 10.8 387. Events that occur when a myelinated axon is injured Figure 10.10 388. Synaptic cleft at a synapse Figure 10.11 389. The synapse Figure 10.12a 390. A transmission electron micrograph of a synaptic knob filled with synaptic vesicles Figure 10.12b 391. A gatelike mechanism can close or open some of the channels in cell membranes through which ions pass Figure 10.13 392. Conditions that lead to the resting potential Figure 10.14 393. A subthreshold depolarization will not result in an action potential Figure 10.15 394. Membrane potential Figure 10.16 395. An oscilloscope records an action potential Figure 10.17 396. Nerve impulse Figure 10.18 397. On a myelinated axon, a nerve impulse appears to jump from node to node Figure 10.19 398. The synaptic knobs of many axons may communicate with the cell body of a neuron Figure 10.20 399. Impulse processing in neuronal pools Figure 10.21 400. Meninges Figure 11.1 401. Meninges of the spinal cord Figure 11.2 402. Ventricles within the cerebral hemispheres and brainstem Figure 11.3a 403. Choroid plexuses in ventricle walls secrete cerebrospinal fluid Figure 11.4 404. Spinal cord Figure 11.5 405. A cross section of the spinal cord Figure 11.6a 406. Micrograph of the spinal cord Figure 11.6b 407. A reflex arc Figure 11.7 408. The knee-jerk reflex Figure 11.8 409. A withdrawal reflex Figure 11.9 410. Maintaining balance with a withdrawal reflex Figure 11.10 411. Major ascending and descending tracts within a cross section of the spinal cord Figure 11.11 412. Sensory impulses originating in skin touch receptors Figure 11.12 413. Most motor fibers of the corticospinal tract begin in the cerebral cortex Figure 11.13 414. A dislocation of the atlas may cause a compression injury to the spinal cord Figure 11C 415. Brain development Figure 11.14 416. The major portions of the brain Figure 11.15a 417. Lobes of the cerebral hemispheres Figure 11.16 418. Some sensory, association, and motor areas of the left cerebral cortex Figure 11.17 419. Functional regions of the cerebral cortex Figure 11.18 420. A coronal section of the left cerebral hemisphere reveals some of the basal nuclei Figure 11.19 421. Brainstem Figure 11.20 6 422. The reticular formation Figure 11.21 423. The cerebellum Figure 11.22 424. Brain waves record fluctuating electrical changes in the brain Figure 11F 425. The structure of a peripheral mixed nerve Figure 11.23 426. The cranial nerves arise from the brainstem Figure 11.25 427. Trigeminal nerves Figure 11.26 428. Facial nerves Figure 11.27 429. Vagus nerves Figure 11.28 430. Spinal nerves Figure 11.29 431. Dermatomes Figure 11.30 432. Spinal nerve Figure 11.31 433. Anterior branches of the spinal nerves in the thoracic region give rise to intercostal nerves Figure 11.32 434. Nerves of the brachial plexus Figure 11.33 435. Nerves of the lumbosacral plexus Figure 11.34 436. Motor pathways Figure 11.35 437. A chain of paravertebral ganglia extends along each side of the vertebral column Figure 11.36 438. Sympathetic fibers Figure 11.37 439. Preganglionic fibers of the sympathetic division of the autonomic nervous system Figure 11.38 440. The preganglionic fibers of the parasympathetic division of the autonomic nervous system Figure 11.39 441. Sympathetic and parasympathetic fibers Figure 11.40 442. Receptors Figure 11.41 443. Touch and pressure receptors Figure 12.1 444. Surface regions to which visceral pain may be referred Figure 12.2 445. Pain originating in the heart may feel as if it is coming from the skin Figure 12.3 446. Increased muscle length stimulates muscle spindles, which stimulate muscle contraction Figure 12.4a 447. Golgi tendon organs occupy tendons, where they inhibit muscle contraction Figure 12.4b 448. Olfactory receptors Figure 12.5 449. Light micrograph of the olfactory epithelium Figure 12.6 450. Taste receptors Figure 12.7 451. A light micrograph of some taste buds Figure 12.8 452. Major parts of the ear Figure 12.9 453. The tensor tympani and the stapedius are effectors in the tympanic reflex Figure 12.10 454. Perilymph and the spiral lamina within the inner ear Figure 12.11 455. The cochlea is a coiled, bony canal with a membranous tube inside Figure 12.12 456. Cochlea Figure 12.13 457. Organ of Corti Figure 12.14 458. Receptors in regions of the cochlear duct sense different frequencies of vibration Figure 12.15 459. The auditory nerve pathway Figure 12.16 460. The saccule and utricle Figure 12.17 461. The maculae respond to changes in head position Figure 12.18 462. Scanning electron micrograph of hairs of hair cells Figure 12.19 463. A crista ampullaris is located within the ampulla of each semicircular canal Figure 12.20 464. Equilibrium Figure 12.21 465. Sagittal section of the closed eyelids and the anterior portion of the eye Figure 12.22 466. The lacrimal apparatus consists of a tear-secreting gland and a series of ducts Figure 12.23 467. The extrinsic muscles of the right eye Figure 12.24 468. Transverse section of the right eye Figure 12.25 469. Anterior portion of the eye Figure 12.26 470. Lens and ciliary body viewed from behind Figure 12.28 471. Accommodation Figure 12.29 472. Aqueous humor Figure 12.30 473. Dim and bright light effects on the iris and pupil Figure 12.31 474. The retina consists of several cell layers Figure 12.32 475. Light micrograph of the retina Figure 12.33 476. Retina Figure 12.34 477. Effects of light passing through glass at an oblique angle Figure 12.35 478. Light waves passing through a lens Figure 12.36 479. The image of an object forms upside down on the retina Figure 12.37 480. Rods and cones Figure 12.38a,b 481. Scanning electron micrograph of rods and cones Figure 12.38c 482. Rhodopsin is embedded in discs of membrane that are stacked within the rod cells Figure 12.39 483. Stereoscopic vision results from formation of two slightly different retinal images Figure 12.40 484. The visual pathway Figure 12.41 485. Types of glands Figure 13.1 486. Chemical communication Figure 13.2 487. Locations of major endocrine glands Figure 13.3 488. Structural formulas of cortisol, norepinephrine, and PGE2 and amino acid sequences of PTH and oxytocin Figure 13.4 489. Steroid hormones Figure 13.5 490. Adenylate cyclase conversion Figure 13.6 491. Nonsteroid hormones Figure 13.7 492. Control of the endocrine system Figure 13.8 493. The pituitary gland Figure 13.9 494. A change in the internal environment alters hormone secretion Figure 13.10 7 495. Negative feedback and hormone concentrations Figure 13.11 496. Hypothalamic releasing hormones stimulate cells of the anterior lobe to secrete hormones Figure 13.12 497. Hypothalamic control of the peripheral endocrine glands may utilize as many as three types of hormones Figure 13.13 498. Light micrograph of the anterior pituitary gland Figure 13.14 499. Hormones released from the hypothalamus and the anterior lobe of the pituitary gland Figure 13.15 500. TRH from the hypothalamus stimulates the anterior pituitary gland to release TSH Figure 13.16 501. The structure of oxytocin differs from that of ADH by only two amino acids, yet they function differently Figure 13.17 502. Thyroid gland Figure 13.18 503. A light micrograph of thyroid gland tissue Figure 13.19 504. The hormones thyroxine and triiodothyronine have very similar molecular structures Figure 13.20 505. Cretinism Figure 13.21 506. Graves disease Figure 13.22 507. Goiter Figure 13.23 508. The parathyroid glands are embedded in the posterior surface of the thyroid gland Figure 13.24 509. Light micrograph of the parathyroid gland Figure 13.25 510. Mechanism by which PTH promotes calcium absorption in the intestine Figure 13.26 511. Parathyroid hormone stimulates bone to release calcium and the kidneys to conserve calcium Figure 13.27 512. Adrenal glands Figure 13.28 513. Light micrograph of the adrenal medulla and the adrenal cortex Figure 13.29 514. Epinephrine and norepinephrine have similar molecular structures and similar functions Figure 13.30 515. Aldosterone increases blood volume and pressure Figure 13.31 516. Cortisol and aldosterone are steroids with similar molecular structures Figure 13.32 517. Negative feedback regulates cortisol secretion Figure 13.33 518. Hormone-secreting cells of the pancreas are grouped in islets that are closely associated with blood vessels Figure 13.34 519. Light micrograph of a pancreatic islet in the pancreas Figure 13.35 520. Insulin and glucagon function together to stabilize blood glucose concentration Figure 13.36 521. During stress, the hypothalamus helps prepare the body for fight or flight Figure 13.37 522. Blood consists of plasma, red blood cells, white blood cells, and platelets Figure 14.1 523. The percentage of red cells (hematocrit) can be determined if a blood-filled capillary tube is centrifuges Figure 14.2 524. Blood cells Figure 14.3 525. Red blood cells Figure 14.4 526. Low blood oxygen causes the kidneys and liver to release erythropoietin Figure 14.5 527. Life cycle of a red blood cell Figure 14.6 528. Light micrographs of red blood cells, normal and abnormal Figure 14.7 529. Structural formulas Figure 14.8 530. A neutrophil has a lobed nucleus with two to five components Figure 14.9 531. An eosinophil has red-staining cytoplasmic granules Figure 14.10 532. A basophil has cytoplasmic granules that stain deep Figure 14.11 533. A monocyte may leave the bloodstream and become a macrophage Figure 14.12 534. The lymphocyte contains a large, spherical nucleus Figure 14.13 535. Diapedesis Figure 14.14 536. Phagocytosis Figure 14.15 537. Blood composition Figure 14.16 538. Steps in platelet plug formation Figure 14.17 539. Schematic of blood-clotting mechanism Figure 14.19 540. Light micrograph of a normal artery Figure 14.20a 541. The inner wall of an artery changed as a result of atherosclerosis Figure 14.20b 542. Different combinations of antigens and antibodies distinguish blood types Figure 14.21 543. Agglutination Figure 14.22 544. Rh factor Figure 14.23 545. The cardiovascular system transports blood throughout the body Figure 15.1 546. Anterior view of a human heart Figure 15.2 547. The heart is posterior to the sternum, where it lies upon the diaphragm Figure 15.3 548. The heart is within the mediastinum and is enclosed by a layered pericardium Figure 15.4 549. Layers of the heart wall: an endocardium, a myocardium, and an epicardium Figure 15.5 550. Coronal sections of the heart Figure 15.6b 551. Photograph of a human tricuspid valve Figure 15.7 552. Photograph of the pulmonary and aortic valves of the heart Figure 15.8 553. The skeleton of the heart Figure 15.9 554. The right and left ventricles Figure 15.10 555. Path of blood through the heart and pulmonary circuit Figure 15.11 556. The openings of the coronary arteries lie just beyond the aortic valve Figure 15.12 8 557. Blood vessels associated with the surface of the heart Figure 15.13a 558. Blood vessels associated with the surface of the heart Figure 15.13b 559. An angiogram (radiograph) of the coronary arteries is used to examine blood vessels Figure 15.14 560. Path of blood through the coronary circulation Figure 15.15 561. The atria empty during atrial systole and fill with blood during atrial diastole Figure 15.16 562. Thoracic regions where the sounds of each heart valve are most easily heard Figure 15.17 563. The cardiac conduction system Figure 15.18 564. Components of the cardiac conduction system Figure 15.19 565. The muscle fibers within the ventricular walls all arranged in patterns of whorls Figure 15.20 566. ECG pattern Figure 15.21 567. A graph of some of the changes that occur in the left ventricle during a cardiac cycle Figure 15.22 568. A prolonged QRS complex may result from damage to the A-V bundle fibers Figure 15.23 569. Autonomic nerve impulses alter the activities of the S-A and A-V nodes Figure 15.24 570. Blood vessels Figure 15.25 571. The smallest arterioles have only a few smooth muscle fibers in their walls Figure 15.26 572. Some metarterioles provide arteriovenous shunts by connecting arterioles directly to venules Figure 15.28 573. Substances are exchanged between blood and tissue fluid through openings separating endothelial cells Figure 15.29a 574. Transmission electron micrograph of a capillary cross section Figure 15.29b-c 575. Light micrograph of a capillary network Figure 15.30 576. Water leaves capillaries because of a net outward pressure at the capillaries' arteriolar ends Figure 15.31 577. Venous valves Figure 15.32 578. Most of the blood volume is contained within the veins and venules Figure 15.33 579. Sites where an arterial pulse is most easily detected Figure 15.34 580. Some of the factors that influence arterial blood pressure Figure 15.35 581. Vasodilation and vasoconstriction Figure 15.36 582. Controlling cardiac output and peripheral resistance regulates blood pressure Figure 15.37 583. If blood pressure rises, baroreceptors initiate the cardioinhibitor reflex Figure 15.38 584. Dilating arterioles helps regulate blood pressure Figure 15.39 585. The massaging action of skeletal muscles helps move blood through the venous system toward the heart Figure 15.40 586. Blood reaches the lungs through branches of the pulmonary arteries; it returns through pulmonary veins Figure 15.41 587. Cells of the alveolar wall are tightly joined Figure 15.42 588. The major blood vessels associated with the heart Figure 15.43 589. Major branches of the abdominal aorta Figure 15.44a 590. Angiogram of the abdominal aorta Figure 15.44b 591. The main arteries of the head and neck Figure 15.45 592. An angiogram of the arteries associated with the head Figure 15.46 593. View of inferior surface of the brain Figure 15.47 594. The main arteries to the shoulder and upper limb Figure 15.48 595. Arteries that supply the thoracic wall Figure 15.49 596. Arteries that supply the pelvic region Figure 15.50 597. Main branches of the external iliac artery Figure 15.51 598. Major vessels of the arterial system Figure 15.52 599. The major veins of the brain, head, and neck Figure 15.53 600. The main veins of the upper limb and shoulder Figure 15.54 601. Veins that drain the thoracic wall Figure 15.55 602. Veins that drain the abdominal viscera Figure 15.56 603. Schematic drawing of the cardiovascular system Figure 15.57 604. The main veins of the lower limb and pelvis Figure 15.58 605. Major vessels of the venous system Figure 15.59 606. Schematic representation of lymphatic vessels transporting fluid from interstitial spaces to the bloodstream Figure 16.1 607. Lymphatic capillaries Figure 16.2 608. Light micrograph of the flaplike valve within a lymphatic vessel Figure 16.3 609. Lymphatic vessels merge into larger lymphatic trunks Figure 16.4 610. A lymphangiogram of the lymphatic vessels and lymph nodes of the pelvic region Figure 16.5 611. Lymphatic pathways Figure 16.6 612. The lymphatic pathway Figure 16.7 613. Tissue fluid enters lymphatic capillaries through flaplike valves between epithelial cells Figure 16.8 614. Lymph enters and leaves a lymph node through lymphatic vessels Figure 16.9 615. A section of a lymph node Figure 16.10a 616. Light micrograph of a lymph node Figure 16.10b 617. Major locations of lymph nodes Figure 16.11 9 618. Thymus and spleen Figure 16.12a 619. Spleen Figure 16.14a 620. Light micrograph of the spleen Figure 16.14b 621. Bone marrow releases undifferentiated lymphocytes Figure 16.16 622. T cell and B cell activation Figure 16.17a 623. Macrophages bind to lymphocytes Figure 16.17b 624. A B cell encounters an antigen that fits its antigen receptor Figure 16.18 625. An activated B cell proliferates after stimulation by cytokines released by helper T cells Figure 16.19 626. An immunoglobin molecule Figure 16.20 627. A primary immune response produces a lesser concentration of antibodies than a secondary response Figure 16.21 628. Immediate-reaction allergy Figure 16.22a 629. A mast cell releases histamine granules Figure 16.22b 630. Scleroderma hardens the skin Figure 16.23 631. Organs of the digestive system Figure 17.1 632. The alimentary canal is a muscular tube about 8 meters long Figure 17.2 633. Layers of the wall of the small intestine: inner mucosa, submucosa, muscular layer, and outer mucosa Figure 17.3 634. Movements through the alimentary canal Figure 17.4 635. The mouth is adapted for ingesting food and preparing it for digestion Figure 17.5 636. The surface of the tongue Figure 17.6 637. Sagittal section of the mouth, nasal cavity, and pharynx Figure 17.7 638. Partially dissected child's skull revealing primary and developing secondary teeth Figure 17.8 639. Permanent teeth: the secondary teeth of the upper and lower jaws Figure 17.9a 640. Permanent teeth: anterior view of the secondary teeth Figure 17.9b 641. A section of a cuspid tooth Figure 17.10 642. Locations of the major salivary glands Figure 17.11 643. Light micrograph of the parotid salivary gland Figure 17.12a 644. Light micrograph of the submandibular salivary gland Figure 17.12b 645. Light micrograph of the sublingual salivary gland Figure 17.12c 646. Muscles of the pharyngeal wall, posterior view Figure 17.13 647. Steps in the swallowing reflex Figure 17.14 648. The esophagus functions as a passageway between the pharynx and the stomach Figure 17.15 649. This cross section of the esophagus shows its muscular wall Figure 17.16 650. Stomach Figure 17.17 651. Radiograph of a stomach Figure 17.18 652. Lining of the stomach Figure 17.19a 653. A light micrograph of cells associated with the gastric glands Figure 17.19b 654. The secretion of gastric juice is regulated in part by parasympathetic nerve impulses Figure 17.20 655. Stomach movements Figure 17.21 656. The enterogastric reflex regulates the rate at which chyme leaves the stomach Figure 17.22 657. The pancreas is closely associated with the duodenum Figure 17.23 658. Acidic chyme entering the duodenum from the stomach Figure 17.24 659. A transverse section of the abdomen reveals the liver and other organs Figure 17.25 660. Lobes of the liver, viewed anteriorly and inferiorly Figure 17.26 661. Hepatic lobe Figure 17.27a-b 662. Light micrograph of hepatic lobules in cross section Figure 17.27c 663. The paths of blood and bile within a hepatic lobule Figure 17.28 664. Falsely colored radiograph of a gallbladder that contains gallstones Figure 17.29 665. Fatty chyme entering the duodenum stimulates the gallbladder to release bile Figure 17.30 666. The three parts of the small intestine are the duodenum, the jejunum, and the ileum Figure 17.31 667. Radiograph showing a normal small intestine containing a radiopaque substance that the patient ingested Figure 17.32 668. Mesentery formed by folds of the peritoneal membrane Figure 17.33 669. The greater omentum hangs like an apron over the abdominal organs Figure 17.34 670. Structure of a single intestinal villus Figure 17.35 671. Light micrograph of intestinal villi from the wall of the duodenum Figure 17.36 672. Intestinal epithelium Figure 17.37a 673. Transmission electron micrograph of microvilli Figure 17.37b 674. Section of small intestine Figure 17.38 675. Digestion breaks down complex carbohydrates into disaccharides Figure 17.39 676. The amino acids that result from dipeptide digestion are absorbed by intestinal villi and enter the blood Figure 17.40 677. Fatty acids and glycerol result from fat digestion Figure 17.41 678. Fat absorption has several steps Figure 17.42 679. Parts of the large intestine Figure 17.43 680. Radiograph of the large intestine containing a radiopaque substance that the patient ingested Figure 17.44 10 681. The rectum and the anal canal are at the distal end of the alimentary canal Figure 17.45 682. Light micrograph of the large intestinal wall Figure 17.46 683. Light micrograph of the large intestinal mucosa Figure 17.47 684. Hormones control body weight Figure 18.1 685. Liver enzymes catalyze reactions that convert the monosaccharides fructose and galactose into glucose Figure 18.2 686. Monosaccharides from foods are used for energy, stored as glycogen, or reacted to produce fat Figure 18.3 687. The body digests fat from foods into glycerol and fatty acids Figure 18.4 688. The liver uses fatty acids to synthesize a variety of lipids Figure 18.5 689. Proteins are digested to their constituent amino acids Figure 18.6 690. The body digests proteins from foods into amino acids Figure 18.7 691. A bomb calorimeter measures the caloric content of a food sample Figure 18.8 692. A molecule of beta carotene can react to form two molecules of retinal, which can react to form retinol Figure 18.10 693. Vitamin D deficiency causes rickets, in which the bones and teeth do not develop normally Figure 18.11 694. Enzymes catalyze reactions that convert niacin from foods into physiologically active niacinamide Figure 18.12 695. Niacinamide is incorporated into molecules of coenzyme 1 Figure 18.13 696. Vitamin B6 includes three similar chemical compounds Figure 18.14 697. Vitamin B12, which has the most complex molecular structure of the vitamins, contains cobalt Figure 18.15 698. Vitamin C is chemically similar to some 6-carbon monosaccharides Figure 18.16 699. Three examples of essential sulfur-containing nutrients Figure 18.18 700. A hemoglobin molecule contains four heme groups Figure 18.19a 701. Normal red blood cells Figure 18.19b 702. Red blood cells containing too little hemoglobin Figure 18.19c 703. Food guide pyramids Figure 18.20 704. Two types of starvation in the young Figure 18.21 705. Organs of the respiratory system Figure 19.1 706. Major features of the upper respiratory tract Figure 19.2 707. Mucus movement in the respiratory tract Figure 19.3 708. Radiographs of the skull Figure 19.4 709. Anterior and posterior views of the larynx Figure 19.5 710. Coronal section and sagittal section of the larynx Figure 19.6 711. The vocal cords as viewed from above the glottis closed and open Figure 19.7a,b 712. Photograph of the glottis and vocal folds Figure 19.7c 713. The trachea transports air between the larynx and the bronchii Figure 19.8 714. Cross section of the trachea Figure 19.9 715. Light micrograph of a section of the tracheal wall Figure 19.10 716. A tracheostomy may be performed to allow air to bypass an obstruction within the larynx Figure 19.11 717. The bronchial tree consists of the passageways that connect the trachea and the alveoli Figure 19.12 718. A plastic cast of the bronchial tree Figure 19.13 719. The respiratory tubes end in tiny alveoli, each of which is surrounded by a capillary network Figure 19.14 720. Light micrograph of alveoli Figure 19.15 721. Oxygen diffuses into the capillary; carbon dioxide diffuses into the alveolus Figure 19.16 722. Locations of the lungs within the thoracic cavity Figure 19.19 723. Left and right pleural spaces Figure 19.20 724. When the lungs are at rest, the pressure inside of the lungs is equal to the pressure outside of the thorax Figure 19.21 725. Moving the plunger of a syringe causes air to move in or out of the syringe Figure 19.22 726. Normal inspiration Figure 19.23 727. Maximal inspiration Figure 19.24 728. Expiration Figure 19.25 729. Respiratory volumes and capacities Figure 19.26 730. A spirometer can be used to measure respiratory air volumes Figure 19.27 731. The respiratory center is located in the pons and the medulla oblongata Figure 19.28 732. The medullary rhythmicity and pneumotaxic areas of the respiratory center control breathing Figure 19.29 733. Decreased blood oxygen concentration stimulates peripheral chemoreceptors Figure 19.30 734. The process of inspiration Figure 19.31 735. Alveolar pores allow air to pass from one alveolus to another Figure 19.32 736. The respiratory membrane Figure 19.33 737. Falsely colored electron micrograph of a capillary located between alveoli Figure 19.34 738. Gases are exchanged between alveolar air and capillary blood because of differences in partial pressures Figure 19.35 11 739. Hemoglobin is completely saturated at normal systemic arterial PO2 Figure 19.36 740. Blood transports oxygen Figure 19.37 741. The amount of oxygen released from oxyhemoglobin increases as PCO2 increases Figure 19.38 742. The amount of oxygen released from oxyhemoglobin increases as the blood pH decreases Figure 19.39 743. The amount of oxygen released from oxyhemoglobin increases as the blood temperature increases Figure 19.40 744. Carbon dioxide produced by tissue cells is transported in several different states Figure 19.41 745. As bicarbonate ions diffuse out of the red blood cell, chloride ions from the plasma diffuse into the cell Figure 19.42 746. In the lungs, carbon dioxide diffuses from the blood into the alveoli Figure 19.43 747. The urinary system includes the kidneys, ureters, urinary bladder, and urethra Figure 20.1 748. Structures of the urinary system are visible in this falsely colored radiograph Figure 20.2 749. Transverse and sagittal sections of the kidneys Figure 20.3 750. The kidney Figure 20.4 751. Blood vessels associated with the kidneys and adrenal glands Figure 20.5 752. Main branches of the renal artery and vein Figure 20.6a 753. Corrosion cast of the renal arterial system Figure 20.6b 754. The glomerular capsule has a visceral layer and a parietal layer Figure 20.8 755. Structure of a nephron and the blood vessels associated with it Figure 20.10 756. Juxtaglomerular apparatus Figure 20.12 757. Cortical nephrons are close to the surface of a kidney; juxtramedullary nephrons are near the renal medulla Figure 20.13 758. The capillary loop of the vasa recta is closely associated with the nephron loop of a juxtamedullary nephron Figure 20.14 759. Pathway of blood through the blood vessels of the kidney and nephron Figure 20.15 760. Capillaries in the kidneys are highly specialized Figure 20.16 761. Glomerular filtration Figure 20.17 762. The rate of glomerular filtration Figure 20.18 763. Relative amounts of glomerular filtrate and urine formed in twenty-four hours Figure 20.19 764. The formation of angiotensin II in the bloodstream Figure 20.20 765. The two processes which contribute to urine formation Figure 20.21 766. In the proximal portion of the renal tubule, osmosis reabsorbs water Figure 20.22 767. In the distal convoluted tubule, potassium ions may be passively secreted Figure 20.23 768. Urine concentrating mechanism Figure 20.24 769. The countercurrent multiplier Figure 20.25 770. A countercurrent mechanism in the vasa recta helps maintain the NaCl concentration gradient Figure 20.26 771. Cross section of a ureter Figure 20.27 772. The urinary bladder Figure 20.28 773. A male urinary bladder Figure 20.29 774. Light micrograph of the human urinary bladder wall Figure 20.30 775. Cross section of the urethra Figure 20.31 776. Male and female urinary bladder and urethra Figure 20.32 777. Water in the body of an average adult male Figure 21.1 778. Cell membranes separate fluid in the intracellular compartment Figure 21.2 779. Extracellular fluid Figure 21.3 780. Net movements of fluids between compartments Figure 21.4 781. Water balance Figure 21.5 782. Electrolyte balance Figure 21.6 783. Potassium ion concentration Figure 21.7 784. Concentration of calcium ions Figure 21.8 785. Some of the metabolic processes that provide hydrogen ions Figure 21.9 786. An increase in carbon dioxide elimination follows as increase in carbon dioxide production Figure 21.10 787. Concentration of hydrogen ions Figure 21.11 788. Chemical buffers act rapidly Figure 21.12 789. Sagittal/posterior view of male reproductive organs Figure 22.1a 790. Sagittal/posterior view of male reproductive organs Figure 22.1b 791. During fetal development, each testis descends through an inguinal canal and enters the scrotum Figure 22.2 792. Structure of the testis Figure 22.3 793. Spermatogonia give rise to primary spermatocytes by mitosis, which give rise to sperm cells by meiosis Figure 22.5 794. Spermatogenesis involves two successive meiotic divisions Figure 22.6 795. Crossing over mixes up traits Figure 22.7 796. As a result of crossing over, the genetic information in sperm cells and egg cells varies from cell to cell Figure 22.8 797. Sperm cell Figure 22.9a 798. Cross section of a human epididymis Figure 22.11 799. Structure of the penis Figure 22.14 12 800. Mechanism of penile erection Figure 22.15 801. Mechanism of emission and ejaculation Figure 22.16 802. The hypothalamus controls sperm cell maturation and development of male secondary sex characteristics Figure 22.17 803. Sagittal view of female reproductive organs Figure 22.18a 804. Transverse section of the female pelvic cavity Figure 22.18b 805. The ovaries are located on each side against the lateral walls of the pelvic cavity Figure 22.19 806. During oogenesis, a single egg cell results from meiosis in a primary oocyte Figure 22.20a 807. Light micrograph of the surface of a mammalian ovary Figure 22.21 808. Structure of a mature follicle Figure 22.22a 809. Light micrograph of a mammalian (monkey) ovary Figure 22.23 810. As a follicle matures, a developing oocyte enlarges and becomes surrounded by follicular cells and fluid Figure 22.25 811. The funnel-shaped infundibulum of the uterine tube partially encircles the ovary Figure 22.26 812. Female external reproductive organs Figure 22.29 813. Mechanism of erection, lubrication, and orgasm in the human female Figure 22.30 814. Control of female secondary sex development Figure 22.31 815. Major events in the female reproductive cycle Figure 22.32 816. Structure of the female breast and mammary glands Figure 22.33 817. Surgical methods of birth control Figure 22.35 818. The paths of the egg and sperm cells through the female reproductive tract Figure 23.1 819. Steps in fertilization Figure 23.3 820. Light micrographs of a human egg, the two-cell stage, and a morula Figure 23.4 821. Stages of early human development Figure 23.5 822. Preimplantation genetic diagnosis probes diseasecausing genes in an eight-celled cleavage embryo Figure 23C 823. After the sixth day of development, the blastocyst contacts the uterine wall and begins to implant Figure 23.6a,b 824. Mechanism that preserves the uterine lining during early pregnancy Figure 23.8 825. Relative concentrations of three hormones in maternal blood during pregnancy Figure 23.9 826. Early in the embryonic stage of development, the three primary germ layers form Figure 23.10 827. Human embryo at three weeks, three and one-half weeks, and about four weeks Figure 23.12 828. Development of an embryo in the fifth through seventh weeks of gestation Figure 23.13a 829. A human embryo after about six weeks of development Figure 23.13b 830. 798A Changes occurring during the fifth to seventh weeks of development Figure 23.14a-d 831. 798B Changes occurring during the fifth to seventh weeks of development Figure 23.14e-g 832. As the amnion develops, it surrounds the embryo and the umbilical cord begins to form Figure 23.15 833. Section of the villus Figure 23.16 834. The placenta consists of an embryonic portion and a maternal portion Figure 23.17 835. The developing placenta as it appears during the seventh week of pregnancy Figure 23.18 836. By the beginning of the eighth week of development, the embryonic body is recognizable as a human Figure 23.19 837. Structures in the developing embryo and fetus are sensitive to specific teratogens Figure 23.20 838. During development, body proportions change considerably Figure 23.21 839. Formation of external reproductive organs Figure 23.22 840. A full-term fetus is usually positioned with its head near the cervix Figure 23.23 841. Oxygen and nutrients diffuse into the fetal blood from the maternal blood Figure 23.24 842. The general pattern of fetal circulation shown anatomically Figure 23.25 843. The general pattern of fetal circulation shown schematically Figure 23.26 844. A positive feedback mechanism propels the birth process Figure 23.27 845. Stages in birth Figure 23.28 846. Mammary glands Figure 23.29 847. Myoepithelial cells contract to release milk Figure 23.30 848. Mechanism that releases milk from the breasts Figure 23.31 849. The neonatal period extends from birth to the end of the fourth week after birth Figure 23.32 850. Major changes occur in the newborn's cardiovascular system Figure 23.33 851. From DNA to gene to chromosome Figure 24.1 852. The gene encoding the CFTR protein is on the seventh largest chromosome Figure 24.2a 853. In cystic fibrosis, the CFTR protein is abnormal, usually missing an amino acid Figure 24.2b 854. Representing the genome and proteome Figure 24.3a 855. Representing the genome and proteome Figure 24.3b 856. A karyotype using the FISH technique Figure 24.4 13 857. Inheritance of cystic fibrosis from carrier parents illustrates autosomal recessive inheritance Figure 24.5 858. Inheritance of Huntington disease from a parent illustrates autosomal dominant inheritance Figure 24.6 859. Incomplete dominance appears in the plasma cholesterol levels of heterozygotes and homozygotes for familial hypercholesterolemia Figure 24.7 860. Photographs illustrating the varying nature of height Figure 24.8 861. Variations in skin color Figure 24.9 862. Variations in eye color Figure 24.10 863. Sex determination Figure 24.11 864. The X and Y chromosomes Figure 24.12 865. Extra or missing chromosomes constitute aneuploidy Figure 24.14 866. Three ways to check a fetus's chromosomes Figure 24.15 867. Ultrasound Figure 24.16 868. Sites of gene therapy and the methods used to introduce normal DNA Figure 24C 14