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4/03/2012
Wednesday
Do Now
• Practice drawing a punnett square
• Read explanation first
• Do Monohybrid only
• In a typical experiment, Mendel mated two
contrasting, true-breeding varieties, a
process called hybridization
• The true-breeding parents are the P
generation
• The hybrid offspring of the P generation
are called the F1 generation
• When F1 individuals self-pollinate, the F2
generation is produced
Copyright © 2008 Pearson Education Inc., publishing as Pearson Benjamin Cummings
Fig. 14-5-1
P Generation
Purple flowers White flowers
Appearance:
Genetic makeup:
PP
pp
Gametes:
P
p
Fig. 14-5-2
P Generation
Purple flowers White flowers
Appearance:
Genetic makeup:
PP
pp
Gametes:
p
P
F1 Generation
Appearance:
Genetic makeup:
Gametes:
Purple flowers
Pp
1/
2
P
1/
2
p
Fig. 14-5-3
P Generation
Purple flowers White flowers
Appearance:
Genetic makeup:
PP
pp
Gametes:
p
P
F1 Generation
Appearance:
Genetic makeup:
Gametes:
Purple flowers
Pp
1/
2
1/
P
2
Sperm
F2 Generation
P
p
PP
Pp
Pp
pp
P
Eggs
p
3
1
p
3
Phenotype
Genotype
Purple
PP
(homozygous)
Purple
Pp
(heterozygous)
1
2
1
Purple
Pp
(heterozygous)
White
pp
(homozygous)
Ratio 3:1
Ratio 1:2:1
1
Mendel used the scientific approach
to identify two laws of inheritance
1. Law of Segragation (The “First Law”)
: the two alleles of an individual for
each trait separate (segregate) during
gamete formation so that each
gamete gets only one of the two
allels
Copyright © 2008 Pearson Education Inc., publishing as Pearson Benjamin Cummings
Table 14-1
• Mendel identified his second law of
inheritance by following two characters at the
same time
• Crossing two true-breeding parents differing
in two characters produces dihybrids
Copyright © 2008 Pearson Education Inc., publishing as Pearson Benjamin Cummings
EXPERIMENT
P Generation
YYRR
yyrr
Gametes
YR

yr
F1 Generation
YyRr
Hypothesis of
independent
assortment
Hypothesis of
dependent
assortment
Predictions
Sperm
or
Predicted
offspring of
F2 generation
1/
Sperm
1/
1/
2
2
YR
1/
YyRr
YYRR
2
1/
4
YR
1/
4
1/
Yr
4
yR
1/
yr
4
YR
YYRR
YYRr
YyRR
YyRr
YYRr
YYrr
YyRr
Yyrr
YyRR
YyRr
yyRR
yyRr
YyRr
Yyrr
yyRr
yyrr
YR
Eggs
1/
yr
2
4
1/
Yr
4
Eggs
yr
yyrr
YyRr
3/
4
1/
1/
yR
4
4
Phenotypic ratio 3:1
1/
yr
4
9/
16
3/
16
3/
16
Phenotypic ratio 9:3:3:1
1/
16
Fig. 14-8b
RESULTS
315
108
101
32
Phenotypic ratio approximately 9:3:3:1
2. Law of Independent Assortment (The
“Second Law”)
: member of each pair of alleles
segregates independently of members
of another pair of factors.
Therefore, all possible contributions of
factors can occur in gametes
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