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Problem or Solution Frame Guiding questions for the problem or solution frame: Problem: (What is the problem?) The need for new antibiotics to to battle resistant bacteria Solution: (What is a possible solution?) Scour nature to find organisms with antibiotic properties. Solution: (What is another possible solution?) Enhance natural germ fighting chemicals to make them more effective or create synthetic antibiotics from scratch using genetics or making a chemical change. Solution: (What is another possible solution?) Restore the effectiveness of older antibiotics by taking away the resistance from bacteria. Solution: (Which solution has the best chance of succeeding?) Possibly restore, because they are already on the market and wouldn't require years of research to approve their use. Scroll to the next page to complete the Summary. Marzano, Robert J. A Handbook for Classroom Instruction that Works, Association for Supervision and Curriculum Development, Alexandria, Virginia, 2001. Summary: The article discusses the problem of finding antibiotics to battle resistant bacteria. It suggests a possible solution as searching nature to find organisms with antibiotic properties. Another suggestion was to create antibiotics through genetics or synthetically. A third suggestions was to restore the effectiveness of current antibiotics. The third suggestion probably has the best chance of succeeding because they are already on the market and wouldn’t require years before approval. Marzano, Robert J. A Handbook for Classroom Instruction that Works, Association for Supervision and Curriculum Development, Alexandria, Virginia, 2001.