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Resource Binder SBI 4U E: Homeostasis Alessia, Laura, Paul, & Sheena AGENDA Essential Question Hook Unit Plan Historical Topic: History of Homeostatic Systems Dry Lab Wet Lab STSE Culminating Activity Recent Research: Article Analysis and Forum Essential Question “What is the effect on homeostasis of the introduction of performance-enhancing drugs?” Hook Mouse Party – Introduces homeostasis of neural systems – Important hook for STSE Activity – http://learn.genetics.utah.edu/content/addicti on/drugs/mouse.html – Not meant to endorse drug use! Dry Lab The Urinary System Exposed! – the urinary system – feedback mechanisms – water balance – effects of alcohol links to the STSE activity! Image from http://www.ciccaracas.org/departments/science/Topic12.php Dry lab – Part A H+, NH3 H2O, HCO3-, NaCl, K+, nutrients NaCl, urea, H2O H2O Afferent arteriole Proximal tubule Loop of Henle descending Collecting duct Glomerulus Bowman’s capsule Loop of Henle ascending Distal tubule Efferent arteriole NaCl H+, K+ NaCl, H2O, HCO3- Dry lab – Part B Comparing solutes in plasma, nephron and urine Sample question: What happened to the levels of urea and ammonia after filtration? Explain why this occurs. Table 1. Concentrations of solutes in the Bowman's capsule, glomerulus, loop of Henle and collecting duct in g/100 mL (from Nelson 2003) Solute protein urea glucose chloride (Cl-) ammonia (NH3) substance X Bowman’s capsule Glomerulus Loop of Henle Collecting duct 0 0.8 0 0 0.05 0.05 1.5 2 0.1 no data 0 0 0.37 no data no data 0.6 0.0001 0.0001 0.0001 0.04 0 9.15 0 0 Dry lab – Part C Antidiuretic hormone (ADH) Negative feedback system Effect of alcohol on ADH and urine formation Osmoreceptors detect high pressure Pituitary gland releases ADH Blood osmotic pressure decreases H2O conserved Wet Lab STSE Culminating Activity Article Analysis and Forum