Download PDF - Breast Centres Network

The Netherlands Cancer Institute - Antoni van Leeuwenhoek
Hospital - Amsterdam, Netherlands
General Information
New breast cancer cases treated per year
550
Breast multidisciplinarity team members
28
Radiologists, surgeons, pathologists, medical oncologists, radiotherapists and
nurses
Clinical Director: Hester Oldenburg, MD, PhD
The Netherlands Cancer Institute / Antoni van Leeuwenhoek Hospital (NKI/AVL) is a Comprehensive Cancer
Centre, combining hospital and research laboratories under one roof, in a single independent organization.
The hospital offers 180 beds, a large radiotherapy department and outpatient clinics. Facilities for patient
research include a large patient database, clinical data management and active research groups in
epidemiology and psychosocial oncology.
The breast unit is part of the surgical department at the cancer institute.
The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital
Plesmanlaan 121
1066 CX Amsterdam, Netherlands
Phone: +31205122551
Fax: +31205122554
E-mail: [email protected]
Web-site: www.nki.nl
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The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital
Available services
Radiology
Breast Surgery
Reconstructive/Plastic Surgery
Pathology
Medical Oncology
Radiotherapy
Nuclear Medicine
Rehabilitation
Genetic Counselling
Data Management
Psycho-oncology
Breast Nurses
Social Workers
Nutritional Counselling
Survivorship Groups
Sexual Health Counselling
Supportive and Palliative Care
Integrative Medicine
Radiology
Dedicated Radiologists
8
Mammograms per year
8000
Breast radiographers
Screening program
Available imaging equipment
Mammography
Vacuum assisted biopsy
tomosyntheses
Axillary US/US-guided
Clinical Research
Core Biopsy (Tru-cut)
Magnetic Resonance Imaging (MRI)
non-palpable breast lesions
FNAB
Stereotactic Biopsy (Mammography
guided)
Ultrasound
Verification for
on specimen
Available breast tissue sampling
equipment
Ultrasound-guided biopsy
Available work-up imaging
equipment
Fine-needle aspiration biopsy
(FNAB, cytology)
Computer Tomography
Core Biopsy
Ultrasound
Vacuum assisted biopsy
Magnetic Resonance Imaging (MRI)
PET/CT scan
MRI-guided biopsy
Core Biopsy
tomosyntheses
Vacuum assisted biopsy
Primary technique for localizing
non-palpable lesions
Hook-wire (or needle localization)
Charcoal marking/tattooing
ROLL: radio-guided occult lesion
localization
Breast Surgery
New operated cases per year (benign and malignant) 750
Dedicated Breast Surgeons
5
Surgeons with more than 50 surgeries per year
5
Breast Surgery beds
Breast Nurse specialists
20
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Primary technique for staging the axilla
Axillary lymph node dissection
Sentinel lymph node biopsy:
Blue dye technique
Outpatient surgery
Radio-tracer technique
Intra-operative evaluation of sentinel node
Blue dye + Radio-tracer
Reconstruction performed by Breast Surgeons
Clinical Research
Axillary sampling
Sentinel node biopsy in primary surgery for cN0 and MARI
procedure for cN1
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The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital
Reconstructive/Plastic Surgery
Reconstructive/Plastic surgeons
Immediate Reconstruction available
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Type of breast reconstructive surgery available
Remodelling after breast-conserving surgery
Reconstruction after mastectomy:
Two-stage reconstruction (tissue expander followed by
implant)
One-stage reconstruction
Autogenous tissue flap
Latissimus dorsi flap
Transverse rectus abdominis (TRAM)
Free-flaps (free TRAM, DIEP, SIEA, gluteal, etc.)
Surgery on the contralateral breast for symmetry
Pathology
Dedicated Breast Pathologists
4
Available studies
Other special studies available
Fluorescence in-situ Hybridization for HER-2 gene (FISH)
Cytology
Oncotype Dx (21-gene assay)
Haematoxylin & eosin section (H&E)
MammaPrint (70-gene microarray)
Surgical specimen
Prediction Analysis of Microarray 50-gene set (PAM 50)
Sentinel node
Parameters included in the final pathology report
Core biopsy
Pathology stage (pT and pN)
Frozen section (FS)
Surgical specimen
Tumour size (invasive component in mm)
Sentinel node
Histologic type
Tumor grade
Immunohistochemistry stain (IHC)
Estrogen receptors
ER/PR receptor status
Progesterone receptors
HER-2/neu receptor status
HER-2
Peritumoural/Lymphovascular invasion
Ki-67
Margin status
Ki-67, P-53, Androgen receptor
Medical Oncology
Dedicated Breast Medical Oncologists
5
Outpatient systemic therapy
Clinical Research
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The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital
Radiotherapy
Dedicated Radiation Oncologists
Clinical Research
Available techniques after breast-conserving surgery
(including experimental)
Whole-Breast RT (WBRT)
Partial breast irradiation (PBI):
External beam PBI
Interstitial brachytherapy
Targeted brachytherapy (MammoSite, SAVI applicator,
other devices)
Intra-operative RT (IORT)
breath hold incl. locoregional breath hold, IMRT, VMAT
Multidisciplinary Meeting (MDM) / Tumour Board (TB)
Regular MDM/TB for case management discussion
Specialties/services participating in MDM/TB
Twice a week
Radiology
Weekly
Breast Surgery
Every two weeks
Reconstructive/Plastic Surgery
Other Schedule
Pathology
Cases discussed at MDM/TB
Medical Oncology
Radiotherapy
Preoperative cases
Postoperative cases
Genetic Counselling
Breast Nurse Service
Psycho-oncology
research physicians, research nurses
Further Services and Facilities
Nuclear Medicine
Lymphoscintigraphy
Bone scan
Positron Emission Tomography (PET)
PET/CT scan
dedicated -mammai- PET, Spect CT scanning, Sentinella
probes
Rehabilitation
Genetic Counselling
Specialist Providing Genetic Counselling/Risk assessment
service:
Dedicated Clinical Geneticist
Medical Oncologist
Breast Surgeon
General Surgeon
Gynaecologist
Genetic Testing available
Prosthesis service
Surveillance program for high-risk women
Physiotherapy
Lymph-oedema treatment
Data Management
Database used for clinical information
Data manager available
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The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital
Contact details
Clinical Director
Hester Oldenburg, MD, PhD
Head of the Breast Unit
[email protected]
+31205122551
Claudette Loo, MD
Staff Member of Radiology Dpt.
[email protected]
Gonneke Winter-Warnars, MD
Staff Member of Radiology Dpt.
[email protected]
+31 20-5121500
M. J. Vrancken Peeters
Staff Member of Surgery Dpt.
[email protected]
+31205129111
Emiel Rutgers
Staff Member of Surgery Dpt.
[email protected]
Senior Staff Member
[email protected]
+31205129111
Senior Staff Member
[email protected]
+31205129111
Sjoerd Rodenhuis
Head of Medical Oncology Division
[email protected]
+31205122870
Sabine Linn, MD, PhD
Senior Staff Member
[email protected]
+31205129111
N. Russell
Staff Member of Radiotherapy Dpt.
[email protected]
Paula Elkhuizen, MD, PhD
Senior Staff Member
[email protected]
+31205129111
Astrid Scholten, MD
Staff Member
[email protected]
+31205129111
Radiology
Breast Surgery
Reconstructive Surgery
Leonie Woerdeman, MD, PhD
Pathology
Jelle Wesseling, MD, PhD
Medical Oncology
Radiotherapy
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The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital
How to reach us
The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital
Plesmanlaan 121
1066 CX Amsterdam, Netherlands
Phone: +31205122551
Fax: +31205122554
E-mail: [email protected]
Web-site: www.nki.nl
From airport:
From Schiphol airport: take the train in direction Amsterdam Central Station, get off at Amsterdam Lelylaan
station (10 minutes).
By bus or sub-way/underground:
From Amsterdam Lelylaan station:
• 5-minute bus ride (64), stopping outside the NKI/AVL (get off at Johan Huizingalaan);
• Metro to Heemstedestraat (1 stop), 10-minute walk from there.
From Amsterdam Central Station:
• tram 2 (get off at Johan Huizingalaan) (45 minutes);
• bus 18 (get off at Johan Huizingalaan) (35 minutes).
By car:
From Den Haag/Schiphol direction Amsterdam (A4):
Exit Sloten/Schinkel/x 107 (second exit after Schiphol tunnel);
at end of the exit road, turn right and follow the road with a bend to the left, passing Mercure Hotel, into the
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The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital
Johan Huizingalaan;
at the second traffic lights, turn left into the Plesmanlaan. Entrance to NKI/AvL is immediately on the left.
Last modified: 31 May 2016
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