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Introduction to Fluids & Electrolytes Learning Objective On completion of this chapter, the learner will be able to: 1. Differentiate between osmosis, diffusion, filtration, and active transport. 2. Describe the role of the kidneys, lungs, and endocrine glands in regulating the body’s fluid composition and volume. 3. Identify the effects of aging on fluid and electrolyte regulation. 4. Plan effective care of patients with the following imbalances: fluid volume deficit and fluid volume excess; sodium deficit (hyponatremia) and sodium excess (hypernatremia); potassium deficit (hypokalemia) and potassium excess (hyperkalemia). . 5. Describe the etiology, clinical manifestations, management, and nursing interventions for the following imbalances: calcium deficit (hypocalcemia) and calcium excess (hypercalcemia); magnesium deficit (hypomagnesemia) and magnesium excess (hypermagnesemia); phosphorus deficit (hypophosphatemia) and phosphorus excess (hyperphosphatemia); chloride deficit (hypochloremia) and chloride excess (hyperchloremia). 6. Explain the role of the lungs, kidneys, and chemical buffers in maintaining acid–base balance. 7. Compare metabolic acidosis and alkalosis with regard to causes, clinical manifestations, diagnosis, and management. 8. Compare respiratory acidosis and alkalosis with regard to causes, clinical manifestations, diagnosis, and management. 9. Interpret arterial blood gas measurements. 10. Demonstrate a safe and effective procedure of venipuncture. 11. Describe measures used for preventing complications of intravenous therapy Nursing Care is directed toward: Assessing for clients at risk Monitoring clients for EARLY manifestations Implement collaborative and nursing interventions to prevent or correct imbalances What segment of the life span is at highest risk of fluid imbalances? Fluid Compartments Intracellular (ICF) fluids contained within the cells Extracellular (ECF) (2/3 of the fluid) (1/3 of the fluid) (Remember blood tests measure extracellular fluid only – that’s why sodium is high and potassium is low!) Interstitial (between the cells) Intravascular (plasma) arteries, veins, capillaries Transcellular misc: urine, digestive secretions, perspiration etc. Theoretical Third Space: trapped ECF in actual or potential body space due to disease or injury Important in burns, shock and cardiovascular Movement of Body Fluids: Important Concept Body fluids are not static. Fluids & electrolytes shift from compartment to compartment. Emphasis is always on maintaining homeostasis FLUID MOVEMENT: review & see Table 11-2, p. 145 (Iggy) Diffusion Osmosis Filtration Active Transport Osmosis Movement of water across a semi-permeable membrane from an area of low solute concentration (lots of water) to an area of high solute concentration (less water) until even distribution (homeostasis) is achieved Osmolarity = number of milli-osmoles in liter of solution Normal = 270 – 300 (or 275 – 295) Osmolality = number of mill-osmoles in kilogram of solution Isotonic Fluids example: normal saline 0.9% NaCl No net fluid (water) shifts occur because the fluids are EQUALLY concentrated Hypotonic Fluids example: 0.45% NaCl When a LESS concentrated fluid is placed next to a MORE concentrated solution, water moves to MORE concentrated solution to equalize the solutions Hypertonic Fluids example: 3% NaCl When a MORE concentrated fluid is placed next to a LESS concentrated solution, water moves to the MORE concentrated solution to equalize the solutions Body Fluids Sources of fluid intake ingested fluids/foods water as byproduct of metabolism Fluid Loss Urine Respiration Perspiration Gastrointestinal tract KIDNEY FUNCTIONS Regulate fluid volume and osmolality Regulate electrolyte levels by selectively retaining & excreting e-lytes Regulate pH (acid/base balance) by selectively retaining & excreting fluids by selectively retaining & excreting H+ Excrete metabolic wastes & toxic substances THE NEPHRON REGULATORY MECHANISMS THIRST KIDNEYS Kidney Function HORMONES Renin-Angiotensin-Aldosterone Anti-Diuretic Hormone Parathormone Anti-Diuretic Hormone (think beer) Parathyroid Hormone Important for Calcium and Phosphorus balance Where are the parathyroid glands???? Dehydration Isotonic dehydration: water & electrolytes lost in equal proportions Hypertonic dehydration: water loss exceeds electrolyte loss Hypotonic dehydration: electrolyte loss exceeds water loss Dehydration Etiology Isotonic: inadequate fluid intake, fluids shifts between compartments, excessive loss of body fluids Hypertonic: excessive perspiration, hyperventilation, fever, diarrhea, ketoacidosis Hypotonic: chronic illness such as renal failure, excessive ingestion hypotonic fluids (babies & water!) DEHYDRATION: FLUID VOLUME DEFICIT nsg dx PATHOPHYSIOLOGY Loss of GI fluids (vomiting, diarrhea, NG suctioning, fistulas, intestinal drainage, chronic abuse of laxatives and/or enemas) Renal loss from diuretics Water loss from sweating or heat Blood loss (hemorrhage) Fluid lost to Third Space (burns, trauma) Dehydration History (risk factors) age (very young & very old) check loss of body weight history of fluid losses Dehydration ASSESSMENT/MANIFESTATIONS Hypotension (decreased systolic, narrowed pulse pressure, postural hypotension) Weak, rapid pulse with collapsed veins Decreased skin turgor, dry membranes Output > Intake (urine high specific gravity) Weight loss (1000 ml = 1000gm or 1 kg (2.2 pounds) ** very important Dehydration Lab Assessment Serum electrolytes abnormal Urine specific gravity high (urine is concentrated) Low central venous pressure Elevated hematocrit and BUN (blood urea nitrogen) Caused by more solute, less water = hemoconcentration Nursing Diagnosis: FLUID VOLUME DEFICIT Diet therapy Oral fluid replacement Oral rehydration therapy Pediatric implications to follow on future slide Drug therapy (varies with type of dehydration) IV = isotonic (safest) 0.9% NaCl, Ringer’s Lactate Meds to treat underlying problem Dehydration: Pediatric Implications Assessment Manifestations FONTANELS (anterior & posterior) Give isotonic fluids Tend to be subtle & happen quickly You have a site to observe on an infant that no longer exists on an adult - ?? Pedialyte (Gatorade) Professional Responsibility Community Based Care: Adults & Children Health teaching Home care management Diet, drugs, & avoidance in the future control environmental temperature & humidification family offers fluids frequently (avoid large amounts plain water in formula fed infant – see under hyponatremia) Health care resources Home care visit Overhydration (nsg dx fluid volume excess) PATHOPHYSIOLOGY Isotonic = hypervolemia Hypotonic = excessive fluid (water intoxication) Hypertonic = rare, excessive sodium intake SUMMARY: TOO MUCH FLUID! Steroids, heart failure, cirrhosis of the liver, renal failure, adrenal gland disorders, excessive intake IV fluids or Sodium (foods, meds, IV solutions) FLUID VOLUME EXCESS ASSESSMENT/MANIFESTATIONS Increased blood pressure Strong, bounding pulse with neck vein distention Taut skin turgor, moist mucous membranes Intake > Output (urine low specific gravity) Weight gain Crackles in lung sounds, orthopnea, irritating cough OVERHYDRATION (FVE) Diagnostic Tests Electrolytes Decreased hematocrit & BUN (Blood urea nitrogen) Caused by more water, less solute = hemodilution Increased central venous pressure Drug therapy Diuretics Sodium & Water Restriction Overhydration Nursing Diagnoses Fluid Volume Excess as above & assess I&O, vital signs, edema daily weights education: sodium Risk for Impaired Skin Integrity Potential: Respiratory Insufficiency