Download Consulta: creatorFacets:"Maalouf, Haifa" Registros recuperados: 7

Consulta: creatorFacets:"Maalouf, Haifa"
Registros recuperados: 7
Data/hora: 09/06/2017 09:16:51
Strain-Dependent Norovirus Bioaccumulation in Oysters
Provedor de dados: 5
Autores: Maalouf, Haifa; Schaeffer, Julien; Parnaudeau, Sylvain; Le Pendu, Jacques; Atmar, Robert L.; Crawford, Sue E.; Le
Guyader, Soizick.
Noroviruses (NoVs) are the main agents of gastroenteritis in humans and the primary pathogens of shellfish-related outbreaks.
Some NoV strains bind to shellfish tissues by using carbohydrate structures similar to their human ligands, leading to the
hypothesis that such ligands may influence bioaccumulation. This study compares the bioaccumulation efficiencies and tissue
distributions in oysters (Crassostrea gigas) of three strains from the two principal human norovirus genogroups. Clear differences
between strains were observed. The GI.1 strain was the most efficiently concentrated strain. Bioaccumulation specifically
occurred in digestive tissues in a dose-dependent manner, and its efficiency paralleled ligand expression, which was highest
during the cold...
Tipo: Text
Ano: 2011
URL: http://archimer.ifremer.fr/doc/00036/14753/12087.pdf
Bovine Norovirus: Carbohydrate Ligand, Environmental Contamination, and Potential Cross-Species
Transmission via Oysters
Provedor de dados: 5
Autores: Zakhour, Maha; Maalouf, Haifa; Di Bartolo, Ilaria; Haugarreau, Larissa; Le Guyader, Francoise; Ruvoen-clouet,
Nathalie; Le Saux, Jean-claude; Ruggeri, Franco Maria; Pommepuy, Monique; Le Pendu, Jacques.
Noroviruses (NoV) are major agents of acute gastroenteritis in humans and the primary pathogens of shellfish-related outbreaks.
Previous studies showed that some human strains bind to oyster tissues through carbohydrate ligands that are similar to their
human receptors. Thus, based on presentation of shared norovirus carbohydrate ligands, oysters could selectively concentrate
animal strains with increased ability to overcome species barriers. In comparison with human GI and GII strains, bovine GIII NoV
strains, although frequently detected in bovine feces and waters of two estuaries of Brittany, were seldom detected in oysters
grown in these estuaries. Characterization of the carbohydrate ligand from a new GIII strain indicated recognition of the...
Tipo: Text
Ano: 2010
URL: http://archimer.ifremer.fr/doc/00014/12534/9527.pdf
Distribution in Tissue and Seasonal Variation of Norovirus Genogroup I and II Ligands in Oysters
Provedor de dados: 5
Autores: Maalouf, Haifa; Zakhour, Maha; Le Pendu, Jacques; Le Saux, Jean-claude; Atmar, Robert L.; Le Guyader, Francoise S.
Bivalve molluscan shellfish, such as oysters, filter large volumes of water as part of their feeding activities and are able to
accumulate and concentrate different types of pathogens, particularly noroviruses, from fecal human pollution. Based on our
previous observation of a specific binding of the Norwalk strain (prototype norovirus genogroup I) to the oyster digestive tract
through an A-like carbohydrate structure indistinguishable from human blood group A antigen and on the large diversity between
strains in terms of carbohydrate-binding specificities, we evaluated the different ligands implicated in attachment to oysters tissues
of strains representative of two main genogroups of human norovirus. The GI.1 and GII.4 strains differed in that the latter...
Tipo: Text
Ano: 2010
URL: http://archimer.ifremer.fr/doc/00011/12215/9045.pdf
Norovirus et huîtres : de la terre à la mer !
Provedor de dados: 5
Autores: Thomas, Adeline; Le Saux, Jean-claude; Ollivier, Joanna; Maalouf, Haifa; Pommepuy, Monique; Le Guyader, Soizick.
Tipo: Text
Ano: 2011
URL: http://archimer.ifremer.fr/doc/00060/17118/14630.pdf
Shellfish contamination by norovirus : strain selection based on ligand expression?
Provedor de dados: 5
Autores: Le Guyader, Soizick; Atmar, Robert; Maalouf, Haifa; Le Pendu, Jacques.
Shellfish can be a vector for human pathogens. Despite regulation based on enteric bacteria, shellfish are still implicated in viral
outbreaks. Oysters are the most common shellfish associated with outbreaks, and noroviruses, which cause acute gastroenteritis,
are the most frequently identified pathogen in these outbreaks. Analysis of shellfish-related outbreak data worldwide shows an
unexpected high proportion of NoV GI strains. Recent studies performed in vitro, in vivo and in the environment indicate that
oysters are not just a passive filter, but can selectively accumulate norovirus strains based on virus carbohydrate ligands shared
with humans. These observations may help explain the GI/GII bias observed in shellfish-related outbreaks compared to...
Tipo: Text
Palavras-chave: Shellfish; Noroviruses; Oyster contamination; Pathogen.
Ano: 2013
URL: http://archimer.ifremer.fr/doc/00150/26093/24313.pdf
Environmental Conditions Leading to Shellfish Contamination and Related Outbreaks
Provedor de dados: 5
Autores: Maalouf, Haifa; Pommepuy, Monique; Le Guyader, Soizick.
Human fecal wastes contain a large variety of viruses that can enter the environment through discharge of waste materials from
infected individuals. Despite the high diversity of viruses that are introduced into the environment by human fecal pollution, only
a few have been recognized to cause disease in association with consumption of contaminated shellfish. To explain bivalve
mollusks contamination, several factors including human epidemiology, virus persistence through sewage treatment plant, and
shellfish uptake may be suggested. Considering different outbreaks described in the literature, the most common route for
transmission is accidental contamination after heavy rainfall, when extra loads cause an overflow, and release of untreated sewage
into the...
Tipo: Text
Palavras-chave: Shellfish; Outbreaks; Norovirus; Environmental conditions.
Ano: 2010
URL: http://archimer.ifremer.fr/doc/00011/12252/9031.pdf
Huîtres et norovirus : une affinité particulière?
Provedor de dados: 5
Autores: Le Guyader, Soizick; Maalouf, Haifa; Le Pendu, Jacques.
Shellfish can be a vector for human pathogens. Despite regulation based on enteric bacteria, shellfish are still implicated in viral
outbreaks. Oysters are the most common shellfish associated with outbreaks, and noroviruses, which cause acute gastroenteritis,
are the most frequently identified pathogen in these outbreaks. Analysis of shellfish-related outbreak data worldwide shows an
unexpected high proportion of genogroup I strains. Recent studies performed in vitro, in vivo and in the environment indicate that
oysters are not just a passive filter, but can selectively accumulate norovirus strains based on virus carbohydrate ligands shared
with humans. These observations may help explain the GI/GII bias observed in shellfish-related outbreaks compared to...
Tipo: Text
Palavras-chave: Huîtres; Norovirus; Ligand; Sélection de souches; Oysters; Norovirus; Ligand; Strain selection.
Ano: 2013
URL: http://archimer.ifremer.fr/doc/00152/26357/24514.pdf