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Centers for Disease Control and Prevention Zika virus disease update Dr Susan Hills Arboviral Diseases Branch September 26, 2016 Laboratory-confirmed Zika virus disease cases reported to ArboNET by states — United States, 2015–2016 (as of Sept 21) Overall 3,358 Zika virus disease cases – Travel-associated cases: 3,314 – Locally acquired mosquito-borne cases: 43 – Laboratory acquired cases: 1 Among the 3,358 cases – Sexually transmitted: 28 – Guillain-Barré syndrome: 8 Laboratory-confirmed Zika virus disease cases reported to ArboNET by territories — United States, 2015–2016 (as of Sept 21) Overall 19,777 Zika virus disease cases – Locally-acquired cases: 19,706 – Travel-associated cases: 71 Among the 19,777 cases – Guillain-Barré syndrome: 37 State of residence for reported Zika virus disease cases — U.S. states, Jan–Jul 2016 (as of Sept 7) State (N=2,382) NY 558 (23%) FL 483 (20%) CA 147 (6%) TX 117 (5%) NJ 90 (4%) PA 74 (3%) Month of illness onset for reported Zika virus disease cases — U.S. states, Jan-Jul 2016 (as of Sept 7) Number of cases 1000 Travel-associated (n=2,354)* 800 Locally-acquired (n=28) 600 400 200 0 Jan Feb Mar Apr May Jun Month of illness onset *Travelers returning from affected areas or their sexual contacts Jul Age group for reported Zika virus disease cases — U.S. states, Jan-Jul 2016 (N=2,382) 600 Number of cases 500 400 300 200 100 0 <10 10–19 20–29 30–39 40–49 Age group (years) 50–59 ≥60 Region where reported U.S. travel-associated Zika virus disease cases were acquired, Jan–Jul 2016* Region Percent Caribbean 65% Central America 18% South America 9% North America Southeast Asia and Pacific Islands 5% <1% *10 persons traveled to >1 region; No direct travel and unknown not listed (<3%) Zika virus reports to PAHO from countries and territories in the Americas Over past 2–4 weeks, most countries have reported a decreasing trend in the numbers of Zika virus disease cases – Unclear how much may be due to changes or delays in reporting Over the full course of the outbreak in 2015–2016 – 15 countries or territories have reported confirmed cases of congenital syndrome associated with Zika virus infection – 7 countries or territories have reported laboratory-confirmed Guillain-Barre syndrome cases associated with Zika virus infection