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ACRIFLAVINE HYDROCHLORIDE
Safety Data Sheet
Emergency Telephone Number: CHEMTREC 1-800-424-9300
For Information call: DUDLEY 732-886-3100
DUDLEY CORPORATION
125 Kenyon Drive
Lakewood, New Jersey 08701
Effective Date: January 1, 2015
1. PRODUCT IDENTIFICATION:Formula CAS. No: 8063-24-9 Formula: C14H14N3Cl
Weight: 259.74
Synonym: 3,6-Diamino-10-Methylacridinium chloride hydrochloride; Euflavine
2. HAZARDS IDENTIFICATION: GHS Classification: Acute toxicity, Oral (Category 4)Serious eye damage (Category 1)
Acute aquatic toxicity (Category 2) Chronic aquatic toxicity (Category 2)
Pictogram:
Signal Word: DANGER
HAZARD STATEMENT(S): H302: Harmful if swallowed H318: Causes serious eye damage.
H411: Toxic to aquatic life with long lasting effects
PRECAUTIONARY STATEMENT(S) : P273: Avoid release into environment P391: Collect Spillage
P264: wash skin thoroughly after handling
P270: Do not drink, eat, smoke, when using this product.
P280: Wear protective gloves/eye & face protection
P330: Rinse mouth
P301 + P312:If Swallowed: Call Poison Center or doctor/physician if you feel unwell
P305 + P351 + P338: If in Eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present &
easy to do so. Continue Rinsing.
P310: Immediately call Poison Center or doctor/physician.
P501: Dispose of contents/container to an approved waste disposal plant.
HMIS Classification: Health hazard 2, Flammability 0, Physical hazards 0
NFPA Rating: Health hazard 2, Fire 0, Reactivity hazard 0
Potential Health Effects : Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through
the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation: Causes respiratory tract irritation. May be harmful if swallowed. Chronic: No data found.
3. COMPOSITION, INFORMATION ON INGREDIENTS:
Chemical Name
CAS No:
Percent
Acriflavine Hydrochloride
8063-24-9
98 - 105%
4. FIRST AID MEASURES: Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper
and lower eyelids. Consult physician. Skin: Flush skin with plenty of soap and water for at least 15 minutes while
removing contaminated clothing and shoes. Consult physician. Ingestion: Do Not induce vomiting. Consult physician.
Wash mouth out with water. NEVER give anything by mouth to an unconscious person. Inhalation: Remove from
exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Consult
physician. Notes to Physician: Treat symptomatically and supportively.
5. FIRE FIGHTING MEASURES: General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use dry
chemicals, water spray, carbon dioxide, or alcohol-resistant foam. Flash Point: Not available.
Auto-ignition Temperature: Not applicable. Explosion Limits: Not Applicable.
6. ACCIDENTAL RELEASE MEASURES: General Information: Use proper PPE as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.
Avoid generating dusty conditions. Ventilate area and wash spill site after material pick-up is complete.
7. HANDLING AND STORAGE: Handling: Use with adequate ventilation. Do not get on skin and clothing. Do not breathe
dust, vapor, mist, or gas. Minimize dust generation and accumulation. Keep container tightly closed.
Storage: Store in a cool, dry, well-ventilated area away from incompatible substances. Keep container tightly closed.
8. EXPOSURE CONTROLS, PERSONAL PROTECTION:
Engineering Controls: Facility storing or utilizing this material should be equipped with an eyewash facility and a safety
shower. Use adequate ventilation to keep airborne concentrations low.
Chemical Name
ACGIH
NIOSH
IARC
OSHA - Final PELs
Acriflavine Hydrochloride
None listed
None listed None listed
None listed
OSHA Vacated PELs: Acriflavine Hydrochloride: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment : Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described
by OSHA’s eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure. Nitrile Rubber 0.11mm thick
Clothing: Wear appropriate suit of protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 N100(US) or European Standard EN
143. Always use a NIOSH or European Standard approved respirator when necessary.
9. PHYSICAL AND CHEMICAL PROPERTIES: State: Powder.
Odor: Odorless. Evaporation Rate: Not available.
Boiling Point: Not available.
Decomposition Temperature: Not available.
Appearance: Orange-red to dark red.
Specific Gravity/Density: Not available.
Melting Point: 260 ° C (500˚F)
Solubility: Not available
10. STABILITY AND REACTIVITY: Stability: Stable under normal temperatures and pressures. Conditions to Avoid:
Incompatible materials. Incompatibilities: Strong oxidizing agents. Decomposition Products: Hydrogen chloride, carbon
monoxide, oxides of nitrogen, carbon dioxide. Hazardous Polymerization: Will not occur.
11. TOXICOLOGICAL INFORMATION: RTECS#: CAS# 8063-24-9 unlisted.
LD50/LC50: Oral-rat 1,048 mg/kg
Carcinogenicity: CAS# 8063-24-9: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: Rabbit, no skin irritation
Teratogenicity: No data available.
Reproductive Effects: No data found.
Neurotoxicity: No data found.
Mutagenicity: No data available.
Other Studies: Cardiovascular effects; central nervous system depression; respiratory disorders
12. ECOLOGICAL INFORMATION: Environmental Fate: Toxic to aquatic life with long lasting effects.
Environmental Toxicity: Toxicity to Fish – LC50-Leuciscus idus (Golden orfe) -1 -10 mg/l -48.0 h
13. DISPOSAL CONSIDERATIONS:
Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA
guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult
state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed. RCRA U-Series: None listed.
14. TRANSPORT INFORMATION:
DOT: Not regulated.
IMDG: UN 3077, ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S., (Acriflavine hydrochloride), 9, III
Marine pollutant: Marine Pollutant
IATA: UN 3077, Environmentally hazardous substance, solid, n.o.s., (Acriflavine hydrochloride), 9, III
15. REGULATORY INFORMATION: Section 311/312: Acute Health Hazard
SARA Section 302 (RQ & TPQ) None of the chemicals in this material have an RQ or TPQ.
Section 313 No chemicals are reportable under Section 313.
Clean Air Act: This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone
depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act: None of the chemicals in this product are listed as Hazardous Substances under the CWA. None of the
chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as
Toxic Pollutants under the CWA.
OSHA: None of the chemicals in this product are considered highly hazardous by OSHA.
STATE CAS# 8063-24-9 is not present on state lists from CA, MN, MA, FL.
PA Right to Know: Acriflavine hydrochloride CAS#8063-24-9 NJ Right to Know: Acriflavine hydrochloride CAS#8063-24-9
California No Significant Risk Level: None of the chemicals in this product are listed.
EUROPEAN/INTERNATIONAL REGULATIONS European Labeling in Accordance with EC Directives
Hazard Symbols: T WGK (Water Danger/Protection) CAS# 8063-24-9: No information available.
Canada - DSL/NDSL None of the chemicals in this product are listed on the DSL or NDSL list.
Canadian Ingredient Disclosure List CAS# 8063-24-9 is not listed on Canada’s Ingredient Disclosure List.
16. DISCLAIMER INFORMATION: DUDLEY CORPORATION provides the information herein in good faith but makes no
representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate
precautionary handling of the material by a properly trained person using this. Individuals receiving the information must
exercise their independent judgment in determining its appropriateness for a particular purpose. DUDLEY CORPORATION
makes no representations or warranties, either expressed or implied, including without limitation and warranties of
merchantability, fitness for a particular purpose with respect to the information set forth herein or to the product to which the
information refers. Accordingly, DUDLEY CORPORATION will not be responsible for damages resulting from the use of or
reliance upon this information.